Publications by authors named "Xuetao Zhou"

4 Publications

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Minimally invasive surgery rib fracture fixation based on location and anatomical landmarks.

Eur J Trauma Emerg Surg 2021 May 13. Epub 2021 May 13.

Department of Cardiothoracic Surgery, Shijiazhuang Third Hospital, No. 15 Tiyu South Street, Shijiazhuang, 050011, Hebei, China.

Background: Rib fracture is closely related to thoracic injury with high morbidity and mortality. This study aimed to investigate the clinical effect of Zhang ZhiFei (ZZF) zoning method on the selection of incision and approach in minimally invasive surgery for rib fracture.

Methods: A total of 110 patients with rib fractures from July 2017 to July 2019 were enrolled in the study. Preoperative computed tomography and three-dimensional reconstruction of ribs was performed. Then, the rib fractures to be surgically fixed were divided into costal cartilage zone, chest zone, lateral costal zone, high posterior costal zone, low posterior costal subscapular zone, and low posterior costal paraspinal zone, which was called ZZF zoning method. Rib fractures in each zone had unique minimally invasive incision approach, and the open reduction and internal fixation of rib fracture was performed under minimally invasive surgery of corresponding small incision.

Results: The average incision length and number of incisions of the 110 patients were 6.2 cm and 1.3, respectively. The average number of internal fixation was 5.3 and the average operation time was 82 min. The postoperative fracture end was well aligned. After 3 months of follow-up, no internal fixation was displaced or detached.

Conclusion: Based on the anatomical characteristics of different zones of the chest wall, ZZF zoning method provides a new idea and reference for the selection of incision and approach in minimally invasive internal fixation for rib fracture.
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http://dx.doi.org/10.1007/s00068-021-01676-2DOI Listing
May 2021

Application of 3D printing and framework internal fixation technology for high complex rib fractures.

J Cardiothorac Surg 2021 Feb 15;16(1). Epub 2021 Feb 15.

Department of Thoracic Surgery, the Second Hospital of Hebei Medical University, No. 215, Heping west road, Shijiazhuang, 050000, China.

Objective: To explore the clinical effect of 3D printing combined with framework internal fixation technology on the minimally invasive internal fixation of high complex rib fractures.

Methods: Total 16 patients with high complex rib fractures were included in the study. Before the procedure, the 3D rib model was reconstructed based on the thin-layer chest CT scan. According to the 3D model, the rib locking plate was pre-shaped, and the preoperative planning were made including the direction of the locking plate, the location of each nail hole and the length of the screw. During the operation, the locking plate was inserted from the sternum to the outermost fracture lines of ribs with screws at both ends. In addition, the locking plate was used as the frame to sequentially reduce the middle fracture segment and fix with screws or steel wires. Chest x-rays or chest CT scans after surgery were used to assess the ribs recovery. All patients were routinely given non-steroidal anti-inflammatory drugs (NSAIDS) for analgesia, and the pain level was evaluated using numerical rating scale (NRS).

Results: The preoperative planning according to the 3D printed rib model was accurate. The reduction and fixation of each fracture segment were successfully completed through the framework internal fixation technology. No cases of surgical death, and postoperative chest pain was significantly alleviated. Five to 10 months follow up demonstrated neither loosening of screws, nor displacement of fixtures among patients. The lungs of each patients were clear and in good shape.

Conclusion: The application of 3D printing combined with framework internal fixation technology to the high complex rib fractures is beneficial for restoring the inherent shape of the thoracic cage, which can realize the accurate and individualized treatment as well as reduces the operation difficulty.
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http://dx.doi.org/10.1186/s13019-020-01377-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883420PMC
February 2021

Correlation of gene polymorphisms of vascular endothelial growth factor with grade and prognosis of lung cancer.

BMC Med Genet 2020 04 30;21(1):86. Epub 2020 Apr 30.

Department of Thoracic Surgery, the Fourth Hospital of Hebei Medical University, 12 Jiankang Road, Shijiazhuang, 050000, China.

Background: Vascular endothelial growth factor (VEGF) gene is highly polymorphic, and single nucleotide polymorphisms (SNP) of VEGF gene are associate with cancer prognosis. This study aimed to analyze the correlation of VEGF gene polymorphisms with grade and prognosis of lung cancer.

Methods: A total of 458 Chinese patients with primary lung cancer were enrolled from September 2008 to October 2013. The genotypes of -2578C > A, -1154G > A, - 460 T > C, and + 405G > C were analyzed in white blood cells from patients using polymerase chain reaction based restriction fragment length polymorphism.

Results: Our data showed that -1154G > A polymorphism was significantly associated with tumor stages, but all four tested VEGF gene polymorphisms had no significant effect on survival.

Conclusions: VEGF polymorphisms may relate to stage of lung cancer in Chinese population.
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http://dx.doi.org/10.1186/s12881-020-01030-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193393PMC
April 2020

3D printing and thoracoscopy assisted MIPO in treatment of long-range comminuted rib fractures, a case report.

J Cardiothorac Surg 2019 Apr 29;14(1):83. Epub 2019 Apr 29.

Department of Cardiothoracic Surgery, The Third Hospital of Shijiazhuang City, Shijiazhuang, 050000, China.

Background: To investigate the application of 3D printing technology combined with percutaneous Minimally Invasive Plate Oseoynthesis (MIPO) and thoracoscopic techniques in the treatment of long comminuted rib fractures.

Case Presentation: One case of multiple rib fractures with abnormal respiratory disease (including rib 3 and 4 of long comminuted fractures) due to a fall injury was selected. The 3D model of comminuted rib fracture was reconstructed and printed according to the thin-layer CT scan results. After the fracture model was restored to the normal rib anatomy, the metal plate was accurately shaped according to the 3D rib shape.

Conclusions: 3D printing technology combined with MIPO technology under thoracoscopy in the minimally invasive treatment of long-range comminuted rib fractures, greatly reduced the time and improved the accuracy of intraoperative fixation, reduced the difficulty of surgery, patient injury, and perfectly reconstructed the chest wall. Application of the 3D printing technique to make the rib model and pre-mold the metal plate combined the thoracoscopic MIPO technology provides less invasive and accurate individualized treatment for complex rib fractures.
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http://dx.doi.org/10.1186/s13019-019-0892-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489358PMC
April 2019