Xuerong Wang

Xuerong Wang

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Xuerong Wang

Xuerong Wang

Publications by authors named "Xuerong Wang"

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Glibenclamide Targets Sulfonylurea Receptor 1 to Inhibit p70S6K Activity and Upregulate KLF4 Expression to Suppress Non-Small Cell Lung Carcinoma.

Mol Cancer Ther 2019 11 24;18(11):2085-2096. Epub 2019 Jul 24.

Department of Pharmacology, Nanjing Medical University, Nanjing, Jiangsu Province, China.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-1181DOI Listing
November 2019

AEG-1 promotes the growth of gastric cancer through the upregulation of eIF4E expression.

Onco Targets Ther 2019 22;12:5887-5895. Epub 2019 Jul 22.

Department of Pathology, Nanjing Medical University Affiliated Nanjing Hospital (Nanjing First Hospital), Nanjing, Jiangsu Province 210006, People's Republic of China.

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http://dx.doi.org/10.2147/OTT.S213604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659790PMC
July 2019

Targeting BRD4 proteins suppresses the growth of NSCLC through downregulation of eIF4E expression.

Cancer Biol Ther 2018 05 6;19(5):407-415. Epub 2018 Feb 6.

a Department of Pharmacology , Nanjing Medical University , Nanjing , Jiangsu Province , China.

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http://dx.doi.org/10.1080/15384047.2018.1423923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915014PMC
May 2018

Enhanced Redox State and Efficiency of Glucose Oxidation With miR Based Suppression of Maladaptive NADPH-Dependent Malic Enzyme 1 Expression in Hypertrophied Hearts.

Circ Res 2018 03 31;122(6):836-845. Epub 2018 Jan 31.

From the Department of Internal Medicine and Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus (A.N.C., E.D.L.); Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL (A.N.C., C.E.G., E.D.L.); Center for Cardiovascular Research, University of Illinois College of Medicine at Chicago (R.L., A.N.C., X.W., J.M.O., E.D.L.); and Translational Research Institute for Diabetes and Metabolism (C.E.G., E.D.L.) and Department of Surgery, Florida Hospital Cardiovascular Institute, Florida Hospital Transplant Center (K.D.A., S.S.), Florida Hospital, Orlando.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.312660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463492PMC
March 2018

AEG-1 induces gastric cancer metastasis by upregulation of eIF4E expression.

J Cell Mol Med 2017 Dec 29;21(12):3481-3493. Epub 2017 Jun 29.

Department of Pharmacology, Nanjing Medical University, Nanjing, Jiangsu, China.

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http://dx.doi.org/10.1111/jcmm.13258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706588PMC
December 2017

Inhibition of p70S6K does not mimic the enhancement of Akt phosphorylation by rapamycin.

Heliyon 2017 Aug 8;3(8):e00378. Epub 2017 Aug 8.

Departments of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S24058440173067
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http://dx.doi.org/10.1016/j.heliyon.2017.e00378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552102PMC
August 2017

Multiphasic Regulation of Systemic and Peripheral Organ Metabolic Responses to Cardiac Hypertrophy.

Circ Heart Fail 2017 Apr;10(4)

From the Department of Physiology and Biophysics (C.W.L., S.X., M.M., H.W.K., A.C.C., J.M.O., E.D.L.) and Center for Cardiovascular Research (X.W., A.C.C., J.M.O., E.D.L.), University of Illinois College of Medicine at Chicago; Department of Kinesiology and Nutrition, University of Illinois at Chicago College of Applied Health Sciences (J.P., G.F.); and Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL (A.C.C., E.D.L.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.117.003864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466817PMC
April 2017

Microbial Hydroxylation of 16α, 17α-Epoxyprogesterone by .

Iran J Pharm Res 2017 ;16(3):1161-1166

Key Laboratory of Industrial Fermentation Microbiology,Ministry of Education,Tianjin University of Science & Technology, Tianjin, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610770PMC
January 2017

Acyl CoA synthetase-1 links facilitated long chain fatty acid uptake to intracellular metabolic trafficking differently in hearts of male versus female mice.

J Mol Cell Cardiol 2016 05 16;94:1-9. Epub 2016 Mar 16.

Center for Cardiovascular Research, University of Illinois College of Medicine at Chicago, 909 South Wolcott Avenue, Chicago, IL 60612, USA; Department of Physiology and Biophysics, University of Illinois College of Medicine at Chicago, 835 South Wolcott Avenue, Chicago, IL 60612, USA; Sanford Burnham Prebys Medical Discovery Institute, 6400 Sanger Road, Orlando, FL 32827, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2016.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861690PMC
May 2016

EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer.

PLoS One 2015 30;10(4):e0125402. Epub 2015 Apr 30.

Department of Nutrition and Food Hygiene, Key Laboratory of Toxicology, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125402PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416002PMC
February 2016

Oroxylin A induces autophagy in human malignant glioma cells via the mTOR-STAT3-Notch signaling pathway.

Mol Carcinog 2015 Nov 11;54(11):1363-75. Epub 2014 Sep 11.

Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing, Jiangsu, China.

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http://dx.doi.org/10.1002/mc.22212DOI Listing
November 2015

Oncogenic miR-9 is a target of erlotinib in NSCLCs.

Sci Rep 2015 Nov 23;5:17031. Epub 2015 Nov 23.

Department of Pharmacology, Nanjing Medical University, Nanjing, Jiangsu Province, China, 210029.

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http://dx.doi.org/10.1038/srep17031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655475PMC
November 2015

GSK3 is required for rapalogs to induce degradation of some oncogenic proteins and to suppress cancer cell growth.

Oncotarget 2015 Apr;6(11):8974-87

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496196PMC
http://dx.doi.org/10.18632/oncotarget.3291DOI Listing
April 2015

Dietary fat supply to failing hearts determines dynamic lipid signaling for nuclear receptor activation and oxidation of stored triglyceride.

Circulation 2014 Nov 29;130(20):1790-9. Epub 2014 Sep 29.

From the Center for Cardiovascular Research, University of Illinois at Chicago College of Medicine, Chicago, IL.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.011687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229424PMC
November 2014

AEG-1 is a target of perifosine and is over-expressed in gastric dysplasia and cancers.

Dig Dis Sci 2013 Oct 4;58(10):2873-80. Epub 2013 Aug 4.

Department of Pathology, Nanjing Medical University Affiliated Nanjing Hospital (Nanjing First Hospital), Nanjing, 210006, Jiangsu, China.

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http://dx.doi.org/10.1007/s10620-013-2735-5DOI Listing
October 2013

Oncogenic MicroRNA-27a is a target for genistein in ovarian cancer cells.

Anticancer Agents Med Chem 2013 Sep;13(7):1126-32

Department of Pharmacology, Nanjing Medical University, Jiangsu, China.

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http://dx.doi.org/10.2174/18715206113139990006DOI Listing
September 2013

Upregulation of the eIF4E signaling pathway contributes to the progression of gastric cancer, and targeting eIF4E by perifosine inhibits cell growth.

Oncol Rep 2013 Jun 9;29(6):2422-30. Epub 2013 Apr 9.

Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China.

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http://dx.doi.org/10.3892/or.2013.2397DOI Listing
June 2013

Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylation.

J Biol Chem 2013 May 27;288(19):13215-24. Epub 2013 Mar 27.

Departments of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia 30322, USA.

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http://www.jbc.org/content/288/19/13215.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M113.463679
Publisher Site
http://dx.doi.org/10.1074/jbc.M113.463679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650361PMC
May 2013

A new dimension to Ras function: a novel role for nucleotide-free Ras in Class II phosphatidylinositol 3-kinase beta (PI3KC2β) regulation.

PLoS One 2012 13;7(9):e45360. Epub 2012 Sep 13.

Department of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0045360PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441633PMC
February 2013

MicroRNA-27a inhibitors alone or in combination with perifosine suppress the growth of gastric cancer cells.

Mol Med Rep 2013 Feb 21;7(2):642-8. Epub 2012 Nov 21.

Department of General Surgery, The Second Affiliated Hospital of South-east University, The Second Hospital of Nanjing, Nanjing 210003, P.R. China.

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https://www.spandidos-publications.com/10.3892/mmr.2012.1191
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http://dx.doi.org/10.3892/mmr.2012.1191DOI Listing
February 2013

Multiphasic triacylglycerol dynamics in the intact heart during acute in vivo overexpression of CD36.

J Lipid Res 2013 Jan 25;54(1):97-106. Epub 2012 Oct 25.

Program in Integrative Cardiac Metabolism, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1194/jlr.M029991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520544PMC
January 2013

Perifosine enhances mTORC1-targeted cancer therapy by activation of GSK3β in NSCLC cells.

Cancer Biol Ther 2012 Sep 24;13(11):1009-17. Epub 2012 Jul 24.

Department of Pharmacology, Nanjing Medical University, Nanjing, Jiangsu, China.

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http://www.tandfonline.com/doi/abs/10.4161/cbt.20989
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http://dx.doi.org/10.4161/cbt.20989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461807PMC
September 2012

MicroRNA-9 suppresses uveal melanoma cell migration and invasion through the NF-κB1 pathway.

Oncol Rep 2012 Sep 6;28(3):961-8. Epub 2012 Jul 6.

Department of Pharmacology, Nanjing Medical University, Nanjing, Jiangsu Province, PR China.

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http://dx.doi.org/10.3892/or.2012.1905DOI Listing
September 2012

Downregulation of IRS-1 promotes metastasis of head and neck squamous cell carcinoma.

Oncol Rep 2012 Aug 1;28(2):659-67. Epub 2012 Jun 1.

Department of Pharmacology, Nanjing Medical University, and Department of Pathology, Nanjing First Hospital, Nanjing, Jiangsu, PR China.

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http://dx.doi.org/10.3892/or.2012.1846DOI Listing
August 2012

Protective role of reactive oxygen species in endotoxin-induced lung inflammation through modulation of IL-10 expression.

J Immunol 2012 Jun 30;188(11):5734-40. Epub 2012 Apr 30.

Section of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois, Chicago, IL 60612, USA.

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http://dx.doi.org/10.4049/jimmunol.1101323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358534PMC
June 2012

Functional PU.1 in macrophages has a pivotal role in NF-κB activation and neutrophilic lung inflammation during endotoxemia.

Blood 2011 Nov 21;118(19):5255-66. Epub 2011 Sep 21.

Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Illinois, Chicago, 60612, USA.

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http://dx.doi.org/10.1182/blood-2011-03-341123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217408PMC
November 2011

Intersectin 1 contributes to phenotypes in vivo: implications for Down's syndrome.

Neuroreport 2011 Oct;22(15):767-72

Department of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1097/WNR.0b013e32834ae348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339866PMC
October 2011

Aspirin suppresses growth of human gastric carcinoma cell by inhibiting survivin expression.

J Biomed Res 2011 Jul;25(4):246-53

Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China;

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http://dx.doi.org/10.1016/S1674-8301(11)60033-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597067PMC
July 2011

Enhancing mTOR-targeted cancer therapy.

Expert Opin Ther Targets 2009 Oct;13(10):1193-203

Emory University School of Medicine, Winship Cancer Institute, Department of Hematology, Atlanta, GA 30322, USA.

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http://www.tandfonline.com/doi/full/10.1517/1472822090322500
Publisher Site
http://dx.doi.org/10.1517/14728220903225008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810099PMC
October 2009

Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors' anticancer efficacy.

Cancer Biol Ther 2008 Dec 8;7(12):1952-8. Epub 2008 Dec 8.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762753PMC
http://dx.doi.org/10.4161/cbt.7.12.6944DOI Listing
December 2008

Enhancing mammalian target of rapamycin (mTOR)-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation.

Cancer Res 2008 Sep;68(18):7409-18

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562339PMC
September 2008

An improved LC-MS/MS method for the quantification of prostaglandins E(2) and D(2) production in biological fluids.

Anal Biochem 2008 Jan 29;372(1):41-51. Epub 2007 Sep 29.

Department of Medicinal Chemistry and Pharmacognosy, University of Illinois College of Pharmacy, Chicago, IL 60612, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00032697070063
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http://dx.doi.org/10.1016/j.ab.2007.08.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276632PMC
January 2008

Akt phosphorylation regulates the tumour-suppressor merlin through ubiquitination and degradation.

Nat Cell Biol 2007 Oct 23;9(10):1199-207. Epub 2007 Sep 23.

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1038/ncb1641DOI Listing
October 2007

The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.

Mol Cancer Ther 2007 Jul 29;6(7):2029-38. Epub 2007 Jun 29.

Winship Cancer Institute, Emory University School of Medicine, 1365-C Clifton Road Northeast, C3088, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-0004DOI Listing
July 2007

Inhibitory kappaB kinase 2 activates airway epithelial cells to stimulate bone marrow macrophages.

Am J Respir Cell Mol Biol 2007 May 4;36(5):562-72. Epub 2007 Jan 4.

Section of Pulmoary, Critical Care and Sleep Medicine, Department of Medicine, University of Illinois, and Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60612, USA.

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http://www.atsjournals.org/doi/abs/10.1165/rcmb.2006-0245OC
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http://dx.doi.org/10.1165/rcmb.2006-0245OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899334PMC
May 2007

NIK is involved in nucleosomal regulation by enhancing histone H3 phosphorylation by IKKalpha.

J Biol Chem 2006 Jul 3;281(27):18684-90. Epub 2006 May 3.

Section of Pulmonary, Critical Care, and Sleep Medicine, University of Illinois, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1074/jbc.M600733200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360958PMC
July 2006

Neuronal chemorepellent Slit2 inhibits vascular smooth muscle cell migration by suppressing small GTPase Rac1 activation.

Circ Res 2006 Mar 26;98(4):480-9. Epub 2006 Jan 26.

Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1161/01.RES.0000205764.85931.4bDOI Listing
March 2006

Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.

Cancer Res 2005 Aug;65(16):7052-8

Department of Hematology and Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-0917DOI Listing
August 2005

[The effect of matrine on the expression of P170 LRP and TOPO II of obtained multi-drug resistance of mouse S180's tumour cell].

Zhong Yao Cai 2004 Nov;27(11):838-40

Shandong Acadmy of Chinese Medicine, Jinan.

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November 2004

EVI1 induces myelodysplastic syndrome in mice.

J Clin Invest 2004 Sep;114(5):713-9

Department of Pathology and Cancer Center, University of Illinois at Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1172/JCI21716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514587PMC
September 2004

[Central suspension operation of hyoid and lower jaw for OSAS].

Lin Chuang Er Bi Yan Hou Ke Za Zhi 2003 Sep;17(9):541-2

Department of Otolaryngology, Second Hospital of Xi'an Jiaotong University, Xi'an 710004.

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September 2003