Xuemian Lu

Xuemian Lu

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Xuemian Lu

Xuemian Lu

Publications by authors named "Xuemian Lu"

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The role of FGF21 in type 1 diabetes and its complications.

Int J Biol Sci 2018 2;14(9):1000-1011. Epub 2018 Jun 2.

The Center of Cardiovascular Disorders, the First Hospital of Jilin University, Changchun, China.

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http://dx.doi.org/10.7150/ijbs.25026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036735PMC
August 2019

Clopidogrel Reduces Fibronectin Accumulation and Improves Diabetes-Induced Renal Fibrosis.

Int J Biol Sci 2019 1;15(1):239-252. Epub 2019 Jan 1.

Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY 40202, USA.

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http://dx.doi.org/10.7150/ijbs.29063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329922PMC
January 2019

Fibroblast growth factor-21 prevents diabetic cardiomyopathy via AMPK-mediated antioxidation and lipid-lowering effects in the heart.

Cell Death Dis 2018 02 14;9(2):227. Epub 2018 Feb 14.

Ruian Center of Chinese-American Research Institute for Diabetic Complications, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

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http://dx.doi.org/10.1038/s41419-018-0307-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833682PMC
February 2018

A novel compound heterozygous mutation in the CYP17A1 gene in a patient with 17α-hydroxylase/17,20-lyase deficiency.

Discov Med 2017 11;24(133):175-182

Department of Endocrinology, Third Affiliated Hospital of Wenzhou Medical University, Ruian, Zhejiang 325200, China.

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November 2017

Physiological and Pharmacological Roles of FGF21 in Cardiovascular Diseases.

J Diabetes Res 2016 9;2016:1540267. Epub 2016 May 9.

The Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou 325035, China; Ruian Center of the Chinese-American Research Institute for Diabetic Complications, The Third Affiliated Hospital, Wenzhou Medical University, Wenzhou 325200, China; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.

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http://dx.doi.org/10.1155/2016/1540267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876232PMC
May 2017

Up-regulation of Nrf2 is involved in FGF21-mediated fenofibrate protection against type 1 diabetic nephropathy.

Free Radic Biol Med 2016 Apr 2;93:94-109. Epub 2016 Feb 2.

The Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou 325035, China; Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY 40202, USA; The Third Affiliated Hospital of the Wenzhou Medical University, Ruian 325200, China; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.02.002DOI Listing
April 2016

ER stress and autophagy dysfunction contribute to fatty liver in diabetic mice.

Int J Biol Sci 2015 2;11(5):559-68. Epub 2015 Apr 2.

3. Chinese-American Research Institute for Diabetic Complications RuiAn Center, the Department of Endocrinology, The Third Affiliated Hospital of Wenzhou Medical University, Ruian, Zhejiang, China, 325200 ; 4. Kosair Children's Hospital Research Institute, the Department of Pediatrics of the University of Louisville, Louisville, KY 40202, USA.

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http://dx.doi.org/10.7150/ijbs.10690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400387PMC
January 2016

Screening strategies for thyroid disorders in the first and second trimester of pregnancy in China.

PLoS One 2014 12;9(6):e99611. Epub 2014 Jun 12.

Department of Endocrinology, The Third Hospital Affiliate to Wenzhou Medical University, Ruian, Zhejiang, China; Ruian Center of the Chinese-American Research Institute for Diabetic Complications, the Third Affiliated Hospital of the Wenzhou Medical University, Ruian, Zhejiang, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099611PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055732PMC
December 2015

Minireview: Roles of Fibroblast Growth Factors 19 and 21 in Metabolic Regulation and Chronic Diseases.

Mol Endocrinol 2015 Oct 26;29(10):1400-13. Epub 2015 Aug 26.

Ruian Center of the Chinese-American Research Institute for Diabetic Complications (F.Z., L.Y., X.Lin, P.C., L.H., X.Lu, Y.T., H.Y., L.C., C.Z.), Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China 325200; Chinese-American Research Institute for Diabetic Complications (F.Z., X.Lin, P.C., L.H., X.Li, Y.T., L.C., C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, China 325035; School of Pharmaceutical Sciences (F.Z., X.Lin, P.C., L.H., X.Li, Y.T., C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, China 325035; and Department of Pediatrics (Y.T., L.C.), University of Louisville, Louisville, Kentucky 40202.

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http://dx.doi.org/10.1210/me.2015-1155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588730PMC
October 2015

Association of Cancer Stem Cell Markers With Aggressive Tumor Features in Papillary Thyroid Carcinoma.

Cancer Control 2015 Oct;22(4):508-14

The Third Affiliated Hospital of Wenzhou Medical University, Ruian, Zhejiang, China.

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http://dx.doi.org/10.1177/107327481502200418DOI Listing
October 2015

Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway.

Diabetologia 2015 Aug 4;58(8):1937-48. Epub 2015 Jun 4.

Chinese-American Research Institute for Diabetic Complication, School of Pharmaceutical Sciences, Wenzhou Medical University, Chashan University-Town, Wenzhou, 325035, People's Republic of China.

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http://dx.doi.org/10.1007/s00125-015-3630-8DOI Listing
August 2015

Adiponectin gene polymorphism rs2241766 T/G is associated with response to pioglitazone treatment in type 2 diabetic patients from southern China.

PLoS One 2014 18;9(11):e112480. Epub 2014 Nov 18.

Department of Endocrinology, the Third Hospital Affiliate to Wenzhou Medical University, Ruian, Zhejiang, China; Ruian Center of the Chinese-American Research Institute for Diabetic Complications, the Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112480PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236071PMC
July 2015

Additive protection by LDR and FGF21 treatment against diabetic nephropathy in type 2 diabetes model.

Am J Physiol Endocrinol Metab 2015 Jul 12;309(1):E45-54. Epub 2015 May 12.

Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, China; Ruian Center of Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, China; Kosair Children's Hospital Research Institute, Department of Pediatrics, the University of Louisville School of Medicine, Louisville, Kentucky.

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http://dx.doi.org/10.1152/ajpendo.00026.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490332PMC
July 2015

Loss of FGF21 in diabetic mouse during hepatocellular carcinogenetic transformation.

Am J Cancer Res 2015 15;5(5):1762-74. Epub 2015 Apr 15.

Chinese-American Research Institute for Diabetic Complications Ruian Center, The Department of Endocrinology, The Third Affiliated Hospital of Wenzhou Medical University Ruian, Zhejiang 325200, China ; Kosair Children's Hospital Research Institute, The Department of Pediatrics of The University of Louisville Louisville, KY 40202.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497442PMC
July 2015

Fibroblast growth factor 21 deletion aggravates diabetes-induced pathogenic changes in the aorta in type 1 diabetic mice.

Cardiovasc Diabetol 2015 06 11;14(1):77. Epub 2015 Jun 11.

Chinese-American Research Institute for Diabetic Complications at the Wenzhou Medical University, Wenzhou, China.

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http://dx.doi.org/10.1186/s12933-015-0241-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484638PMC
June 2015

Multiple low-dose radiation prevents type 2 diabetes-induced renal damage through attenuation of dyslipidemia and insulin resistance and subsequent renal inflammation and oxidative stress.

PLoS One 2014 20;9(3):e92574. Epub 2014 Mar 20.

Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, China; Kosair Children's Hospital Research Institute at the Department of Pediatrics, University of Louisville, Louisville, Kentucky, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092574PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961432PMC
November 2014

Attenuation of hyperlipidemia- and diabetes-induced early-stage apoptosis and late-stage renal dysfunction via administration of fibroblast growth factor-21 is associated with suppression of renal inflammation.

PLoS One 2013 9;8(12):e82275. Epub 2013 Dec 9.

Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China ; Ruian Center of the Chinese-American Research Institute for Diabetic Complications, Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, Zhejiang, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082275PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857822PMC
October 2014

The prevention of diabetic cardiomyopathy by non-mitogenic acidic fibroblast growth factor is probably mediated by the suppression of oxidative stress and damage.

PLoS One 2013 9;8(12):e82287. Epub 2013 Dec 9.

Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China ; Departments of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky, United States of America ; Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville, Louisville, Kentucky, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082287PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857250PMC
October 2014

Low-dose radiation induces renal SOD1 expression and activity in type 1 diabetic mice.

Int J Radiat Biol 2014 Mar;90(3):224-30

Ruian Center of the Chinese-American Research Institute for Diabetic Complications, the Third Affiliated Hospital of the Wenzhou Medical College , Wenzhou.

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http://www.tandfonline.com/doi/full/10.3109/09553002.2014.87
Publisher Site
http://dx.doi.org/10.3109/09553002.2014.877174DOI Listing
March 2014

Adiponectin and peroxisome proliferator-activated receptor-γ gene polymorphisms and gene-gene interactions with type 2 diabetes.

Life Sci 2014 Mar 15;98(1):55-9. Epub 2014 Jan 15.

Department of Endocrinology, The Third Hospital Affiliate to Wenzhou Medical University, Ruian, Zhejiang 325200, China; Ruian Center of the Chinese-American Research Institute for Diabetic Complications, The Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou 325200, China. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2013.12.232DOI Listing
March 2014

Diabetes-induced hepatic pathogenic damage, inflammation, oxidative stress, and insulin resistance was exacerbated in zinc deficient mouse model.

PLoS One 2012 12;7(12):e49257. Epub 2012 Dec 12.

Ruian Center of the Chinese-American Research Institute for Diabetic Complications, The Third Affiliated Hospital of the Wenzhou Medical College, Wenzhou, Zhejiang, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049257PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520990PMC
June 2013