Xue-Qian Zhang

Xue-Qian Zhang

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Xue-Qian Zhang

Xue-Qian Zhang

Publications by authors named "Xue-Qian Zhang"

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52Publications

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The central role of protein kinase C epsilon in cyanide cardiotoxicity and its treatment.

Toxicol Sci 2019 Jun 7. Epub 2019 Jun 7.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Pennsylvania State University College of Medicine, Hershey, PA.

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http://dx.doi.org/10.1093/toxsci/kfz137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735853PMC
June 2019

Methylene Blue Counteracts HS-Induced Cardiac Ion Channel Dysfunction and ATP Reduction.

Cardiovasc Toxicol 2018 10;18(5):407-419

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.

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http://dx.doi.org/10.1007/s12012-018-9451-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126975PMC
October 2018

Methylene blue counteracts cyanide cardiotoxicity: cellular mechanisms.

J Appl Physiol (1985) 2018 05 8;124(5):1164-1176. Epub 2018 Feb 8.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Pennsylvania State University College of Medicine , Hershey, Pennsylvania.

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http://dx.doi.org/10.1152/japplphysiol.00967.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050200PMC
May 2018

Uremic encephalopathy with isolated brainstem involvement revealed by magnetic resonance image: a case report.

BMC Neurol 2017 Aug 8;17(1):154. Epub 2017 Aug 8.

Department of Neurology, The Second Hospital of Hebei Medical University, Hebei, Shijiazhuang, 050000, People's Republic of China.

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http://dx.doi.org/10.1186/s12883-017-0936-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549307PMC
August 2017

Methylene blue counteracts H2S toxicity-induced cardiac depression by restoring L-type Ca channel activity.

Am J Physiol Regul Integr Comp Physiol 2016 06 9;310(11):R1030-44. Epub 2016 Mar 9.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania;

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http://dx.doi.org/10.1152/ajpregu.00527.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935501PMC
June 2016

BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes.

J Mol Cell Cardiol 2016 Mar 19;92:10-20. Epub 2016 Jan 19.

Center of Translational Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA; Department of Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2016.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789075PMC
March 2016

Cardiac Dysfunction in HIV-1 Transgenic Mouse: Role of Stress and BAG3.

Clin Transl Sci 2015 Aug 24;8(4):305-10. Epub 2015 Aug 24.

Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/cts.12331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841629PMC
August 2015

Regulation of L-type calcium channel by phospholemman in cardiac myocytes.

J Mol Cell Cardiol 2015 Jul 25;84:104-11. Epub 2015 Apr 25.

Center of Translational Medicine, Temple University School of Medicine, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468006PMC
July 2015

Ca²⁺ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance.

Am J Physiol Heart Circ Physiol 2015 Mar 9;308(6):H637-50. Epub 2015 Jan 9.

Center of Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania; Division of Nephrology, Temple University School of Medicine, Philadelphia, Pennsylvania;

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http://dx.doi.org/10.1152/ajpheart.00720.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360055PMC
March 2015

Induced overexpression of phospholemman S68E mutant improves cardiac contractility and mortality after ischemia-reperfusion.

Am J Physiol Heart Circ Physiol 2014 Apr 31;306(7):H1066-77. Epub 2014 Jan 31.

Center of Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania;

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http://dx.doi.org/10.1152/ajpheart.00861.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962630PMC
April 2014

[Protective effects of crude polysaccharides from Chroogomphus rutilus on SH-SY5Y cells impaired by MPP(+)].

Sheng Li Xue Bao 2013 Apr;65(2):210-6

College of Life Sciences, Hebei Normal University, Shijiazhuang 050024, China.

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April 2013

Cardioprotection of controlled and cardiac-specific over-expression of A(2A)-adenosine receptor in the pressure overload.

PLoS One 2012 6;7(7):e39919. Epub 2012 Jul 6.

Department of Physiology, Cardiovascular Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039919PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391213PMC
March 2013

Coordinated regulation of cardiac Na(+)/Ca (2+) exchanger and Na (+)-K (+)-ATPase by phospholemman (FXYD1).

Adv Exp Med Biol 2013 ;961:175-90

Center of Translational Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1007/978-1-4614-4756-6_15DOI Listing
March 2013

Phospholemman deficiency in postinfarct hearts: enhanced contractility but increased mortality.

Clin Transl Sci 2012 Jun 27;5(3):235-42. Epub 2012 Mar 27.

Cardiovascular Division, Department of Medicine, University of Virginia Medical Center, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1111/j.1752-8062.2012.00403.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891564PMC
June 2012

Residues 248-252 and 300-304 of the cardiac Na+/Ca2+ exchanger are involved in its regulation by phospholemman.

Am J Physiol Cell Physiol 2011 Oct 6;301(4):C833-40. Epub 2011 Jul 6.

Division of Nephrology, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1152/ajpcell.00069.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191572PMC
October 2011

Regulation of in vivo cardiac contractility by phospholemman: role of Na+/Ca2+ exchange.

Am J Physiol Heart Circ Physiol 2011 Mar 30;300(3):H859-68. Epub 2010 Dec 30.

Division of Nephrology and Center of Translational Medicine, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1152/ajpheart.00894.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064295PMC
March 2011

Phospholemman: a novel cardiac stress protein.

Clin Transl Sci 2010 Aug;3(4):189-96

Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/j.1752-8062.2010.00213.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013348PMC
August 2010

Effects of cardiac-restricted overexpression of the A(2A) adenosine receptor on adriamycin-induced cardiotoxicity.

Am J Physiol Heart Circ Physiol 2010 Jun 2;298(6):H1738-47. Epub 2010 Apr 2.

Center for Translational Medicine, Dept. of Medicine, Jefferson Medical College, 1025 Walnut St, Suite 822 College, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1152/ajpheart.00688.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886639PMC
June 2010

Phospholemman and beta-adrenergic stimulation in the heart.

Am J Physiol Heart Circ Physiol 2010 Mar 11;298(3):H807-15. Epub 2009 Dec 11.

Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1152/ajpheart.00877.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838560PMC
March 2010

Induced overexpression of Na+/Ca2+ exchanger transgene: altered myocyte contractility, [Ca2+]i transients, SR Ca2+ contents, and action potential duration.

Am J Physiol Heart Circ Physiol 2009 Aug 12;297(2):H590-601. Epub 2009 Jun 12.

Department of Medicine, Division of Nephrology, Center of Translational Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1152/ajpheart.00190.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724197PMC
August 2009

Phospholemman regulates cardiac Na+/Ca2+ exchanger by interacting with the exchanger's proximal linker domain.

Am J Physiol Cell Physiol 2009 Apr 21;296(4):C911-21. Epub 2009 Jan 21.

Division of Nephrology, Thomas Jefferson Univ., 833 Chestnut St., Suite 700, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1152/ajpcell.00196.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670646PMC
April 2009

Regulation of cardiac myocyte contractility by phospholemman: Na+/Ca2+ exchange versus Na+ -K+ -ATPase.

Am J Physiol Heart Circ Physiol 2008 Oct 15;295(4):H1615-25. Epub 2008 Aug 15.

Division of Nephrology, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1152/ajpheart.00287.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593504PMC
October 2008

Regulation of cardiac Na+/Ca2+ exchanger by phospholemman.

Ann N Y Acad Sci 2007 Mar;1099:119-34

Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA.

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http://dx.doi.org/10.1196/annals.1387.004DOI Listing
March 2007

Altered contractility and [Ca2+]i homeostasis in phospholemman-deficient murine myocytes: role of Na+/Ca2+ exchange.

Am J Physiol Heart Circ Physiol 2006 Nov 2;291(5):H2199-209. Epub 2006 Jun 2.

Dept. of Cellular and Molecular Physiology, Milton S. Hershey Medical Center, MC-H166, Hershey, PA 17003, USA.

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http://dx.doi.org/10.1152/ajpheart.01181.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1593220PMC
November 2006

Cytoplasmic tail of phospholemman interacts with the intracellular loop of the cardiac Na+/Ca2+ exchanger.

J Biol Chem 2006 Oct 18;281(42):32004-14. Epub 2006 Aug 18.

Department of Cellular and Molecular Physiology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, Pennsylvania 17033, USA.

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http://dx.doi.org/10.1074/jbc.M606876200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1613256PMC
October 2006

Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation.

J Biol Chem 2006 Mar 23;281(12):7784-92. Epub 2006 Jan 23.

Department of Cellular and Molecular Physiology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, Pennsylvania 17033, USA.

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http://dx.doi.org/10.1074/jbc.M512092200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1405234PMC
March 2006

Effects of sarcoplasmic reticulum Ca2+-ATPase overexpression in postinfarction rat myocytes.

J Appl Physiol (1985) 2005 Jun 27;98(6):2169-76. Epub 2005 Jan 27.

Dept. of Cellular & Molecular Physiology, Milton S. Hershey Medical Center, MC-H166, Hershey, PA 17003, USA.

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http://dx.doi.org/10.1152/japplphysiol.00013.2005DOI Listing
June 2005

Serine 68 of phospholemman is critical in modulation of contractility, [Ca2+]i transients, and Na+/Ca2+ exchange in adult rat cardiac myocytes.

Am J Physiol Heart Circ Physiol 2005 May 14;288(5):H2342-54. Epub 2005 Jan 14.

Department of Cellular and Molecular Physiology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, Pennsylvania 17033, USA.

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http://dx.doi.org/10.1152/ajpheart.01133.2004DOI Listing
May 2005

Identification of an endogenous inhibitor of the cardiac Na+/Ca2+ exchanger, phospholemman.

J Biol Chem 2005 May 17;280(20):19875-82. Epub 2005 Mar 17.

Department of Cellular and Molecular Physiology, Pennsylvania State University, Hershey, 17033, USA.

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http://dx.doi.org/10.1074/jbc.M414703200DOI Listing
May 2005

Sprint training improves contractility in postinfarction rat myocytes: role of Na+/Ca2+ exchange.

J Appl Physiol (1985) 2004 Aug 9;97(2):484-90. Epub 2004 Apr 9.

Weis Center for Research, Geisinger Medical Center, Danville, PA 17822-2619, USA.

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http://dx.doi.org/10.1152/japplphysiol.00061.2004DOI Listing
August 2004

Exercise training improves cardiac function postinfarction: special emphasis on recent controversies on na+/ca2+ exchanger.

Exerc Sport Sci Rev 2004 Jul;32(3):83-9

Weis Center for Research, Geisinger Medical Center, Danville, PA 17822, USA.

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http://dx.doi.org/10.1097/00003677-200407000-00002DOI Listing
July 2004

Effects of phospholemman downregulation on contractility and [Ca(2+)]i transients in adult rat cardiac myocytes.

Am J Physiol Heart Circ Physiol 2004 Apr 18;286(4):H1322-30. Epub 2003 Dec 18.

Department of Medicine, Geisinger Medical Center, Danville, PA 17822-2619, USA.

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http://dx.doi.org/10.1152/ajpheart.00997.2003DOI Listing
April 2004

Phospholemman modulates Na+/Ca2+ exchange in adult rat cardiac myocytes.

Am J Physiol Heart Circ Physiol 2003 Jan 26;284(1):H225-33. Epub 2002 Sep 26.

Weis Center for Research and Department of Medicine, Geisinger Medical Center, Danville, Pennsylvania 17822, USA.

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http://dx.doi.org/10.1152/ajpheart.00698.2002DOI Listing
January 2003

Rescue of contractile abnormalities by Na+/Ca2+ exchanger overexpression in postinfarction rat myocytes.

J Appl Physiol (1985) 2002 Dec 16;93(6):1925-31. Epub 2002 Aug 16.

Weis Center for Research, Geisinger Medical Center, Danville, Pennsylvania 17822, USA.

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http://dx.doi.org/10.1152/japplphysiol.00583.2002DOI Listing
December 2002

Effects of Na(+)/Ca(2+) exchanger downregulation on contractility and [Ca(2+)](i) transients in adult rat myocytes.

Am J Physiol Heart Circ Physiol 2002 Oct 27;283(4):H1616-26. Epub 2002 Jun 27.

Department of Medicine, Geisinger Medical Center, Danville, Pennsylvania 17822, USA.

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http://dx.doi.org/10.1152/ajpheart.00186.2002DOI Listing
October 2002

Effects of sprint training on contractility and [Ca(2+)](i) transients in adult rat myocytes.

J Appl Physiol (1985) 2002 Oct;93(4):1310-7

Weis Center for Research, Geisinger Medical Center, Danville, Pennsylvania 17822, USA.

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http://www.physiology.org/doi/10.1152/japplphysiol.01071.200
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http://dx.doi.org/10.1152/japplphysiol.01071.2001DOI Listing
October 2002

Overexpression of phospholemman alters contractility and [Ca(2+)](i) transients in adult rat myocytes.

Am J Physiol Heart Circ Physiol 2002 Aug;283(2):H576-83

Weis Center for Research, Geisinger Medical Center, Danville, PA 17822, USA.

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http://www.physiology.org/doi/10.1152/ajpheart.00197.2002
Publisher Site
http://dx.doi.org/10.1152/ajpheart.00197.2002DOI Listing
August 2002