Publications by authors named "Xudong Wu"

100Publications

MiR-21-5p actions at the Smad7 gene during pig ovarian granulosa cell apoptosis.

Anim Reprod Sci 2020 Nov 2;223:106645. Epub 2020 Nov 2.

College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, PR China; Key Laboratory of Local Animal Genetic Resources Conservation and Bio-Breeding of Anhui Province, Hefei, 230036, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.anireprosci.2020.106645DOI Listing
November 2020

Identification of Signatures of Selection by Whole-Genome Resequencing of a Chinese Native Pig.

Front Genet 2020 17;11:566255. Epub 2020 Sep 17.

Key Laboratory of Pig Molecular Quantitative Genetics of Anhui Academy of Agricultural Sciences, Anhui Provincial Key Laboratory of Livestock and Poultry Product Safety Engineering, Institute of Animal Husbandry and Veterinary Medicine, Anhui Academy of Agricultural Sciences, Hefei, China.

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http://dx.doi.org/10.3389/fgene.2020.566255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527633PMC
September 2020

CircFOXP1/FOXP1 promotes osteogenic differentiation in adipose-derived mesenchymal stem cells and bone regeneration in osteoporosis via miR-33a-5p.

J Cell Mol Med 2020 Nov 30;24(21):12513-12524. Epub 2020 Sep 30.

Department of Orthopaedics, Zhoushan Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University, Zhejiang, China.

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http://dx.doi.org/10.1111/jcmm.15792DOI Listing
November 2020

Organocatalytic asymmetric synthesis of arylindolyl indolin-3-ones with both axial and central chirality.

Chem Commun (Camb) 2020 Oct;56(83):12648-12651

Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China.

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http://dx.doi.org/10.1039/d0cc05432aDOI Listing
October 2020

Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH.

Redox Biol 2020 Sep 8;36:101634. Epub 2020 Jul 8.

State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Drum Tower Hospital, School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing, 210023, China. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2020.101634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369618PMC
September 2020

Typically inhibiting USP14 promotes autophagy in M1-like macrophages and alleviates CLP-induced sepsis.

Cell Death Dis 2020 Aug 20;11(8):666. Epub 2020 Aug 20.

State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Drum Tower Hospital, School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing, 210023, China.

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http://dx.doi.org/10.1038/s41419-020-02898-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441392PMC
August 2020

Triggering a switch from basal- to luminal-like breast cancer subtype by the small-molecule diptoindonesin G via induction of GABARAPL1.

Cell Death Dis 2020 Aug 15;11(8):635. Epub 2020 Aug 15.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Han Kou Road, Nanjing, 210093, China.

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http://dx.doi.org/10.1038/s41419-020-02878-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429843PMC
August 2020

Analysis of Local Chromatin States Reveals Gene Transcription Potential during Mouse Neural Progenitor Cell Differentiation.

Cell Rep 2020 Jul;32(4):107953

National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of the Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107953DOI Listing
July 2020

Comparison of severity scores for COVID-19 patients with pneumonia: a retrospective study.

Eur Respir J 2020 09 10;56(3). Epub 2020 Sep 10.

Institute of Respiratory Medicine, Chinses Academy of Medical Sciences, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Disease, Beijing, China.

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http://dx.doi.org/10.1183/13993003.02113-2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366179PMC
September 2020

Chemodivergent transformations of amides using gem-diborylalkanes as pro-nucleophiles.

Nat Commun 2020 06 19;11(1):3113. Epub 2020 Jun 19.

State Key Laboratory for Oxo Synthesis and Selective Oxidation, Suzhou Research Institute, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, PR China.

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http://dx.doi.org/10.1038/s41467-020-16948-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305144PMC
June 2020

Dynamic growth models for Caragana korshinskii shrub biomass in China.

J Environ Manage 2020 Sep 22;269:110675. Epub 2020 May 22.

Research Institute of Desertification Control, Ningxia Academy of Agriculture and Forestry Science, Yinchuan, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jenvman.2020.110675DOI Listing
September 2020

Serial scanning electron microscopy of anti-PKHD1L1 immuno-gold labeled mouse hair cell stereocilia bundles.

Sci Data 2020 06 17;7(1):182. Epub 2020 Jun 17.

Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1038/s41597-020-0509-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299942PMC
June 2020

Hierarchical Micro-Nano Topography Promotes Cell Adhesion and Osteogenic Differentiation via Integrin α2-PI3K-AKT Signaling Axis.

Front Bioeng Biotechnol 2020 19;8:463. Epub 2020 May 19.

Department of Prosthodontics, School and Hospital of Stomatology, Tianjin Medical University, Tianjin, China.

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http://dx.doi.org/10.3389/fbioe.2020.00463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248375PMC
May 2020

Non-Targeted Metabolomic Profiling of Coronary Heart Disease Patients With Taohong Siwu Decoction Treatment.

Front Pharmacol 2020 8;11:651. Epub 2020 May 8.

Department of Pathophysiology, Chinese PLA General Hospital, Beijing, China.

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http://dx.doi.org/10.3389/fphar.2020.00651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227603PMC
May 2020

Competition between PAF1 and MLL1/COMPASS confers the opposing function of LEDGF/p75 in HIV latency and proviral reactivation.

Sci Adv 2020 May 13;6(20):eaaz8411. Epub 2020 May 13.

State Key Laboratory of Experimental Hematology, Tianjin Key Laboratory of Medical Epigenetics, Tianjin Key Laboratory of Cellular Homeostasis and Human Diseases, Department of Cell Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China.

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http://dx.doi.org/10.1126/sciadv.aaz8411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220354PMC
May 2020

Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.

Science 2020 04;368(6489)

Howard Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/science.aaz2449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380553PMC
April 2020

Comparison of clinical efficacy between laparotomy and laparoscopic radical surgery for gastric cancer and their effects on CRP, CEA and insulin resistance.

J BUON 2020 Jan-Feb;25(1):324-331

Department of Gastroenterological Surgery, Dongying People's Hospital, Dongying 257091, P.R. China.

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April 2020

Comparison of clinical efficacy between laparotomy and laparoscopic radical surgery for gastric cancer and their effects on CRP, CEA and insulin resistance.

J BUON 2020 Jan-Feb;25(1):255-261

Department of Gastroenterological Surgery, Dongying People's Hospital, Dongying 257091, P.R. China.

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April 2020

Deregulation of tumor suppressive ASXL1 - PTEN/AKT axis in myeloid malignancies.

J Mol Cell Biol 2020 Apr 1. Epub 2020 Apr 1.

Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Key Laboratory of Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Cell Biology, Tianjin Medical University, Tianjin 300070, China.

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http://dx.doi.org/10.1093/jmcb/mjaa011DOI Listing
April 2020

RYBP/YAF2-PRC1 complexes and histone H1-dependent chromatin compaction mediate propagation of H2AK119ub1 during cell division.

Nat Cell Biol 2020 04 23;22(4):439-452. Epub 2020 Mar 23.

National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

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http://dx.doi.org/10.1038/s41556-020-0484-1DOI Listing
April 2020

A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.

N Engl J Med 2020 05 18;382(19):1787-1799. Epub 2020 Mar 18.

From the Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases (B.C., Yeming Wang, G.F., F.Z., X.G., Z.L., Y.Z., Hui Li, L.S., C.W.), and the Institute of Clinical Medical Sciences (G.F., X.G.), China-Japan Friendship Hospital, the Institute of Respiratory Medicine, Chinese Academy of Medical Sciences (B.C., Yeming Wang, F.Z., Z.L., Y.Z., Hui Li, C.W.), the Clinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University (Xingwang Li), Peking University Clinical Research Institute, Peking University First Hospital (C.D.), Tsinghua University School of Medicine (Jiuyang Xu), Beijing University of Chinese Medicine (L.S.), NHC Key Laboratory of Systems Biology of Pathogens and Christophe Merieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences (L.G.), and Peking Union Medical College (L.G., C.W.), Beijing, and Jin Yin-tan Hospital, Wuhan (D.W., W.L., Jingli Wang, L.R., B.S., Y.C., M.W., Jiaan Xia, N.C., Jie Xiang, T.Y., T.B., X.X., L.Z., C.L., Y.Y., H.C., Huadong Li, H.H., S.T., F.G., Y.L., Yuan Wei, K.W., K.L., X.Z., X.D., Z.Q., Sixia Lu, X.H., S.R., Shanshan Luo, Jing Wu, Lu Peng, F.C., Lihong Pan, J.Z., C.J., Juan Wang, Xia Liu, S.W., X.W., Q.G., J.H., H.Z., F.Q., C.H., D.Z.) - all in China; Lancaster University, Lancaster (T.J.), and the University of Oxford, Oxford (P.W.H.) - both in the United Kingdom; and the University of Virginia School of Medicine, Charlottesville (F.G.H.).

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http://dx.doi.org/10.1056/NEJMoa2001282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121492PMC
May 2020

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.

Lancet 2020 03 11;395(10229):1054-1062. Epub 2020 Mar 11.

Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China; Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China; Department of Respiratory Medicine, Capital Medical University, Beijing, China; Tsinghua University School of Medicine, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(20)30566-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270627PMC
March 2020

ncHMR detector: a computational framework to systematically reveal non-classical functions of histone modification regulators.

Genome Biol 2020 02 24;21(1):48. Epub 2020 Feb 24.

Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.

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http://dx.doi.org/10.1186/s13059-020-01953-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038559PMC
February 2020

Characteristics and in situ remediation effects of heavy metal immobilizing bacteria on cadmium and nickel co-contaminated soil.

Ecotoxicol Environ Saf 2020 Apr 7;192:110294. Epub 2020 Feb 7.

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610065, Sichuan, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ecoenv.2020.110294DOI Listing
April 2020

Transcriptomic comparison of liver tissue between Anqing six-end-white pigs and Yorkshire pigs based on RNA sequencing.

Genome 2020 Apr 13;63(4):203-214. Epub 2020 Jan 13.

Anhui Provincial Laboratory of Local Animal Genetic Resource Conservation and Bio-Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei, Anhui 230036, China.

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http://dx.doi.org/10.1139/gen-2019-0105DOI Listing
April 2020

Transcriptional analysis of deoxynivalenol-induced apoptosis of sow ovarian granulosa cell.

Reprod Domest Anim 2020 Feb 26;55(2):217-228. Epub 2020 Jan 26.

Anhui Provincial Laboratory of Local Animal Genetic Resource Conservation and Bio-Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei, China.

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http://dx.doi.org/10.1111/rda.13610DOI Listing
February 2020

Fine mapping of the MHC region identifies major independent variants associated with Han Chinese primary biliary cholangitis.

J Autoimmun 2020 02 4;107:102372. Epub 2019 Dec 4.

Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei, China, Key Laboratory of Dermatology (Anhui Medical University), Ministry of Education, Hefei, China, Key Laboratory of Major Autoimmune Diseases, Anhui Province, Hefei, China, 218 Jixi Road, Hefei, Anhui, 230022, China. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2019.102372DOI Listing
February 2020

LDAF1 and Seipin Form a Lipid Droplet Assembly Complex.

Dev Cell 2019 12 7;51(5):551-563.e7. Epub 2019 Nov 7.

Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02124, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2019.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235935PMC
December 2019

Quantifying global CH and NO footprints.

J Environ Manage 2019 Dec 17;251:109566. Epub 2019 Sep 17.

School of Management, China University of Mining & Technology (Beijing), Beijing, 100083, PR China; State Key Laboratory of Coal Resources and Safe Mining, University of Mining & Technology (Beijing), Beijing, 100083, PR China; Harvard China Project, School of Engineering and Applied Sciences, Harvard University, MA, 02138, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jenvman.2019.109566DOI Listing
December 2019

Genome-Wide CRISPR-Cas9 Screening Identifies NF-κB/E2F6 Responsible for EGFRvIII-Associated Temozolomide Resistance in Glioblastoma.

Adv Sci (Weinh) 2019 Sep 24;6(17):1900782. Epub 2019 Jul 24.

Tianjin Neurological Institute Key Laboratory of Post-Neurotrauma Neuro-Repair and Regeneration in Central Nervous System Ministry of Education and Tianjin City Tianjin 300052 China.

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http://dx.doi.org/10.1002/advs.201900782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724471PMC
September 2019

Genomic analysis reveals selection signatures of the Wannan Black pig during domestication and breeding.

Asian-Australas J Anim Sci 2020 May 23;33(5):712-721. Epub 2019 Aug 23.

College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.

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http://ajas.info/journal/view.php?doi=10.5713/ajas.19.0289
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http://dx.doi.org/10.5713/ajas.19.0289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206397PMC
May 2020

PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing.

Nat Commun 2019 08 23;10(1):3801. Epub 2019 Aug 23.

Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA, 02115, USA.

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http://www.nature.com/articles/s41467-019-11712-w
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http://dx.doi.org/10.1038/s41467-019-11712-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707252PMC
August 2019

Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b.

Protein Cell 2020 03 17;11(3):161-186. Epub 2019 Jul 17.

College of Life Sciences, Renmin Hospital of Wuhan University, Medical Research Institute at School of Medicine, Wuhan University, Wuhan, 430072, China.

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http://dx.doi.org/10.1007/s13238-019-0650-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026249PMC
March 2020

Chiral Phosphoric Acid Catalyzed Asymmetric Addition of 2-(Vinyloxy)ethanol to Imines and Applications of the Products.

Org Lett 2019 07 21;21(13):5335-5340. Epub 2019 Jun 21.

Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry , Tsinghua University , Beijing 100084 , China.

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http://dx.doi.org/10.1021/acs.orglett.9b01970DOI Listing
July 2019

Loss of hnRNP A1 in murine skeletal muscle exacerbates high-fat diet-induced onset of insulin resistance and hepatic steatosis.

J Mol Cell Biol 2020 May;12(4):277-290

State Key Laboratory of Pharmaceutical Biotechnology, Department of Biotechnology and Pharmaceutical Sciences, School of Life Sciences, Nanjing University, Nanjing 210023, China.

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http://dx.doi.org/10.1093/jmcb/mjz050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232127PMC
May 2020

Application of a Strontium-Loaded, Phase-Transited Lysozyme Coating to a Titanium Surface to Enhance Osteogenesis and Osteoimmunomodulation.

Med Sci Monit 2019 Apr 11;25:2658-2671. Epub 2019 Apr 11.

Tianjin Medical University School and Hospital of Stomatology, Tianjin, China (mainland).

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http://dx.doi.org/10.12659/MSM.914269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476409PMC
April 2019

Axially Chiral Cyclic Phosphoric Acid Enabled Enantioselective Sequential Additions.

Org Lett 2019 04 3;21(8):2498-2503. Epub 2019 Apr 3.

School of Chemistry and Chemical Engineering , Beijing Institute of Technology , Beijing 100081 , China.

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http://dx.doi.org/10.1021/acs.orglett.8b04012DOI Listing
April 2019

cis-Khellactone Inhibited the Proinflammatory Macrophages via Promoting Autophagy to Ameliorate Imiquimod-Induced Psoriasis.

J Invest Dermatol 2019 09 13;139(9):1946-1956.e3. Epub 2019 Mar 13.

Department of Rheumatology and Immunology, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Drum Tower Hospital, School of Life Sciences, Nanjing University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.02.021DOI Listing
September 2019

ALYREF links 3'-end processing to nuclear export of non-polyadenylated mRNAs.

EMBO J 2019 05 11;38(9). Epub 2019 Mar 11.

State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences University of Chinese Academy of Sciences, Shanghai, China

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http://dx.doi.org/10.15252/embj.201899910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484419PMC
May 2019

NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.

Genes Dev 2019 05 6;33(9-10):536-549. Epub 2019 Mar 6.

State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1101/gad.322602.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499326PMC
May 2019

Relationship between porcine miR-20a and its putative target low-density lipoprotein receptor based on dual luciferase reporter gene assays.

Asian-Australas J Anim Sci 2019 Jul 3;32(7):922-929. Epub 2019 Jan 3.

Anhui Provincial Laboratory of Local Animal Genetic Resource Conservation and Bio-Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei, Anhui 230036, China.

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http://dx.doi.org/10.5713/ajas.18.0510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601058PMC
July 2019

Structure of the post-translational protein translocation machinery of the ER membrane.

Nature 2019 02 31;566(7742):136-139. Epub 2018 Dec 31.

Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41586-018-0856-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367035PMC
February 2019

Knockdown of LINC02465 Suppresses Gastric Cancer Cell Growth and Metastasis Via PI3K/AKT Pathway.

Hum Gene Ther Clin Dev 2019 03 7;30(1):19-28. Epub 2019 Feb 7.

Department of Gastroenterology, First People's Hospital of Yancheng City, Yancheng, Jiangsu Province, China.

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https://www.liebertpub.com/doi/10.1089/humc.2018.177
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http://dx.doi.org/10.1089/humc.2018.177DOI Listing
March 2019

Isosteviol Protects Free Fatty Acid- and High Fat Diet-Induced Hepatic Injury Modulating PKC-β/p66Shc/ROS and Endoplasmic Reticulum Stress Pathways.

Antioxid Redox Signal 2019 06 28;30(17):1949-1968. Epub 2019 Jan 28.

3 Department of Microbiology and Immunology, Virginia Commonwealth University and McGuire Veterans Affairs Medical Center, Richmond, Virginia.

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https://www.liebertpub.com/doi/10.1089/ars.2018.7521
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http://dx.doi.org/10.1089/ars.2018.7521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486675PMC
June 2019

PRMT2 links histone H3R8 asymmetric dimethylation to oncogenic activation and tumorigenesis of glioblastoma.

Nat Commun 2018 10 31;9(1):4552. Epub 2018 Oct 31.

Department of Cell Biology, Tianjin Medical University, 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Key Laboratory of Medical Epigenetics, Qixiangtai Road 22, Tianjin, 300070, China.

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http://www.nature.com/articles/s41467-018-06968-7
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http://dx.doi.org/10.1038/s41467-018-06968-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208368PMC
October 2018

Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages.

Br J Pharmacol 2019 01 4;176(2):317-333. Epub 2018 Dec 4.

State Key Laboratory of Pharmaceutical Biotechnology, Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, School of Life Sciences, Nanjing University, Nanjing, China.

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http://dx.doi.org/10.1111/bph.14521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295420PMC
January 2019

Inducible SHP-2 activation confers resistance to imatinib in drug-tolerant chronic myeloid leukemia cells.

Toxicol Appl Pharmacol 2018 12 2;360:249-256. Epub 2018 Oct 2.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0041008X183045
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http://dx.doi.org/10.1016/j.taap.2018.09.044DOI Listing
December 2018

A multicenter retrospective study of endoscopic submucosal tunnel dissection for large lesser gastric curvature superficial neoplasms.

Surg Endosc 2019 06 27;33(6):1910-1919. Epub 2018 Sep 27.

Department of Gastroenterology, Jiangsu Province People's Hospital, Jiangyin, 214400, China.

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http://dx.doi.org/10.1007/s00464-018-6471-yDOI Listing
June 2019

Dielectrophoretic separation of microalgae cells in ballast water in a microfluidic chip.

Electrophoresis 2019 03 30;40(6):969-978. Epub 2018 Sep 30.

College of Information Science and Technology, Dalian Maritime University, Dalian, P. R. China.

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http://dx.doi.org/10.1002/elps.201800302DOI Listing
March 2019

mRNAs are sorted for export or degradation before passing through nuclear speckles.

Nucleic Acids Res 2018 09;46(16):8404-8416

State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1093/nar/gky650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144872PMC
September 2018

Mechanistic insights into ER-associated protein degradation.

Curr Opin Cell Biol 2018 08 30;53:22-28. Epub 2018 Apr 30.

Howard Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ceb.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131047PMC
August 2018

Low-frequency band gap of locally resonant phononic crystals with a dual-base plate.

J Acoust Soc Am 2018 03;143(3):1326

Clean Energy Automotive Engineering Center, TongJi University, NO.4800, Cao'an Road, Shanghai 201804, China.

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http://dx.doi.org/10.1121/1.5025041DOI Listing
March 2018

A novel combination of astilbin and low-dose methotrexate respectively targeting AAR and its ligand adenosine for the treatment of collagen-induced arthritis.

Biochem Pharmacol 2018 07 2;153:269-281. Epub 2018 Feb 2.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00062952183003
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http://dx.doi.org/10.1016/j.bcp.2018.01.033DOI Listing
July 2018

FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathway.

Cell Death Dis 2018 01 19;9(2):46. Epub 2018 Jan 19.

Department of Cell Biology, 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Key Laboratory of Medical Epigenetics, Tianjin Medical University, Tianjin, 300070, China.

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http://www.nature.com/articles/s41419-017-0066-8
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http://dx.doi.org/10.1038/s41419-017-0066-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833345PMC
January 2018

Iridium-Catalyzed Enantioselective Synthesis of Dihydroimidazoquinazolinones by Elaborate Tuning of Chiral Cyclic Ligands.

Org Lett 2017 12 21;19(23):6376-6379. Epub 2017 Nov 21.

Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University , Beijing 100084, China.

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http://dx.doi.org/10.1021/acs.orglett.7b03230DOI Listing
December 2017

(+)-Borneol improves the efficacy of edaravone against DSS-induced colitis by promoting M2 macrophages polarization via JAK2-STAT3 signaling pathway.

Int Immunopharmacol 2017 Dec 10;53:1-10. Epub 2017 Oct 10.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2017.10.002DOI Listing
December 2017

ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo.

Nucleic Acids Res 2017 Sep;45(16):9640-9653

State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1093/nar/gkx597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766156PMC
September 2017

Small-molecule RL71-triggered excessive autophagic cell death as a potential therapeutic strategy in triple-negative breast cancer.

Cell Death Dis 2017 09 14;8(9):e3049. Epub 2017 Sep 14.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China.

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http://dx.doi.org/10.1038/cddis.2017.444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636988PMC
September 2017

Exosome cofactor hMTR4 competes with export adaptor ALYREF to ensure balanced nuclear RNA pools for degradation and export.

EMBO J 2017 10 11;36(19):2870-2886. Epub 2017 Aug 11.

State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China

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http://dx.doi.org/10.15252/embj.201696139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623860PMC
October 2017

A natural compound jaceosidin ameliorates endoplasmic reticulum stress and insulin resistance via upregulation of SERCA2b.

Biomed Pharmacother 2017 May 17;89:1286-1296. Epub 2017 Mar 17.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2017.03.023DOI Listing
May 2017

Berberine inhibits palmitate-induced NLRP3 inflammasome activation by triggering autophagy in macrophages: A new mechanism linking berberine to insulin resistance improvement.

Biomed Pharmacother 2017 May 6;89:864-874. Epub 2017 Mar 6.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing 210023, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2017.03.003DOI Listing
May 2017

Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV.

Mol Ther 2017 02 9;25(2):379-391. Epub 2017 Jan 9.

Department of Neurology, Massachusetts General Hospital and NeuroDiscovery Center, Harvard Medical School, Building 149, Charlestown, Boston, MA 02129, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2016.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368844PMC
February 2017

CUG-binding protein 1 regulates HSC activation and liver fibrogenesis.

Nat Commun 2016 11 17;7:13498. Epub 2016 Nov 17.

State Key Laboratory of Pharmaceutical Biotechnology and Collaborative Innovation Center of Chemistry for Life Sciences, School of Life Sciences, Nanjing University, Nanjing 210023, China.

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http://dx.doi.org/10.1038/ncomms13498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118555PMC
November 2016

Development of Axially Chiral Cyclo-Biaryldiol Ligands with Adjustable Dihedral Angles.

Chemistry 2016 Nov 13;22(48):17477-17484. Epub 2016 Oct 13.

Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, P.R. China.

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http://dx.doi.org/10.1002/chem.201603706DOI Listing
November 2016

Inhibition of autophagy by andrographolide resensitizes cisplatin-resistant non-small cell lung carcinoma cells via activation of the Akt/mTOR pathway.

Toxicol Appl Pharmacol 2016 Nov 14;310:78-86. Epub 2016 Sep 14.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2016.09.009DOI Listing
November 2016

Prevalent Accumulation of Non-Optimal Codons through Somatic Mutations in Human Cancers.

Authors:
Xudong Wu Guohui Li

PLoS One 2016 11;11(8):e0160463. Epub 2016 Aug 11.

Laboratory of Molecular Modeling and Design, State key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Rd., Dalian 116023, PR China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160463PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981346PMC
July 2017

Stuxnet detected, Pc breaks down.

Authors:
Xudong Wu

Sci China Life Sci 2016 11 28;59(11):1202-1203. Epub 2016 Jul 28.

Department of Cell Biology, 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Key Laboratory of Medical Epigenetics, Tianjin Medical University, Tianjin, 300070, China.

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http://dx.doi.org/10.1007/s11427-016-5108-4DOI Listing
November 2016

Application of novel endoloops to close the defects resulted from endoscopic full-thickness resection with single-channel gastroscope: a multicenter study.

Surg Endosc 2017 02 28;31(2):837-842. Epub 2016 Jun 28.

Department of Gastroenterology, The First People's Hospital of Yancheng City, Yancheng, China.

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http://dx.doi.org/10.1007/s00464-016-5041-4DOI Listing
February 2017

Systems Level Analysis of Histone H3 Post-translational Modifications (PTMs) Reveals Features of PTM Crosstalk in Chromatin Regulation.

Mol Cell Proteomics 2016 08 14;15(8):2715-29. Epub 2016 Jun 14.

From the ‡Centre for Epigenetics and VILLUM Center for Bioanalytical Sciences, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark;

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http://dx.doi.org/10.1074/mcp.M115.054460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974346PMC
August 2016

Isomeranzin suppresses inflammation by inhibiting M1 macrophage polarization through the NF-κB and ERK pathway.

Int Immunopharmacol 2016 Sep 7;38:175-85. Epub 2016 Jun 7.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 163 Xian Lin Road, Nanjing 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2016.05.027DOI Listing
September 2016

Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.

PLoS One 2016 19;11(5):e0155577. Epub 2016 May 19.

Department of Neurobiology, Harvard Medical School and Howard Hughes Medical Institute, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0155577PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873267PMC
July 2017

Obaculactone protects against bleomycin-induced pulmonary fibrosis in mice.

Toxicol Appl Pharmacol 2016 07 11;303:21-29. Epub 2016 May 11.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2016.05.005DOI Listing
July 2016

Acid-Promoted Cross-Dehydrative Aromatization for the Synthesis of Tetraaryl-Substituted Pyrroles.

Org Lett 2016 Jan 18;18(1):56-9. Epub 2015 Dec 18.

College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University , Wuhan 430072, P. R. China.

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http://dx.doi.org/10.1021/acs.orglett.5b03240DOI Listing
January 2016

Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity.

Proc Natl Acad Sci U S A 2015 Dec 14;112(52):15988-93. Epub 2015 Dec 14.

Department of Cell Biology, 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, Laboratory of Epigenetics in Development and Tumorigenesis, Tianjin Research Center of Basic Medical Sciences, Tianjin Key Laboratory of Medical Epigenetics, Tianjin Medical University, Tianjin 300070, China;

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http://dx.doi.org/10.1073/pnas.1521740112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702963PMC
December 2015

Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer.

Oncotarget 2015 Nov;6(35):37613-25

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.

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http://dx.doi.org/10.18632/oncotarget.6068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741952PMC
November 2015

CPT-11 activates NLRP3 inflammasome through JNK and NF-κB signalings.

Toxicol Appl Pharmacol 2015 Dec 30;289(2):133-41. Epub 2015 Sep 30.

Department of Oncology, The First Affiliated Hospital with Nanjing Medical University, 300, Guangzhou Road, Nanjing 210029, China. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2015.09.025DOI Listing
December 2015

Obaculactone exerts a novel ameliorating effect on contact dermatitis through regulating T lymphocyte.

Int Immunopharmacol 2015 Sep 21;28(1):1-9. Epub 2015 May 21.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2015.05.015DOI Listing
September 2015

Decrease of Functional Activated T and B Cells and Treatment of Glomerulonephitis in Lupus-Prone Mice Using a Natural Flavonoid Astilbin.

PLoS One 2015 13;10(4):e0124002. Epub 2015 Apr 13.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124002PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395080PMC
March 2016

Preferential cytotoxicity of bortezomib toward highly malignant human liposarcoma cells via suppression of MDR1 expression and function.

Toxicol Appl Pharmacol 2015 Feb 6;283(1):1-8. Epub 2015 Jan 6.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2014.12.015DOI Listing
February 2015

Novel role of Sarco/endoplasmic reticulum calcium ATPase 2 in development of colorectal cancer and its regulation by F36, a curcumin analog.

Biomed Pharmacother 2014 Oct 29;68(8):1141-8. Epub 2014 Oct 29.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22, Hankou Road, Nanjing 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2014.10.014DOI Listing
October 2014

EGFR inhibitor-driven endoplasmic reticulum stress-mediated injury on intestinal epithelial cells.

Life Sci 2014 Dec 31;119(1-2):28-33. Epub 2014 Oct 31.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2014.10.008DOI Listing
December 2014

Neochromine S5 improves contact hypersensitivity through a selective effect on activated T lymphocytes.

Biochem Pharmacol 2014 Nov 11;92(2):358-68. Epub 2014 Sep 11.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093, China. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2014.08.032DOI Listing
November 2014

HIV protease inhibitors in gut barrier dysfunction and liver injury.

Curr Opin Pharmacol 2014 Dec 6;19:61-6. Epub 2014 Aug 6.

McGuire Veterans Affairs Medical Center, Richmond, VA 23249, United States; School of Pharmacy, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China; Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA 23298, United States. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2014.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253060PMC
December 2014