Xu Shen

Xu Shen

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Molecular evolution in large steps - Codon substitutions under positive selection.

Mol Biol Evol 2019 May 11. Epub 2019 May 11.

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.

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http://dx.doi.org/10.1093/molbev/msz108DOI Listing
May 2019

Brucine alleviates neuropathic pain in mice via reducing the current of the sodium channel.

J Ethnopharmacol 2019 Apr 30;233:56-63. Epub 2018 Dec 30.

School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023 Jiangsu, China; Key Laboratory for Chinese Medicine of Prevention and Treatment in Neurological Diseases, Nanjing University of Chinese Medicine, 138 Xian in Rd, Nanjing, 210023 Jiangsu, China; State Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing 210023, China; Key Laboratory of Drug Target and Drug for Degenerative Disease of Jiangsu Province, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2018.12.045DOI Listing
April 2019

Oral cholecalciferol supplementation alleviates lipopolysaccharide-induced preterm delivery partially through regulating placental steroid hormones and prostaglandins in mice.

Int Immunopharmacol 2019 Apr 7;69:235-244. Epub 2019 Feb 7.

Department of Toxicology, Anhui Medical University, Hefei 230032, China; Key Laboratory of Environmental Toxicology, Anhui Higher Education Institutes, Anhui Medical University, Hefei 230032, China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei 230032, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2019.01.052DOI Listing
April 2019

TGF-β1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM.

EBioMedicine 2019 Apr 27;42:458-469. Epub 2019 Mar 27.

Department of Analytical Chemistry, CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; E-Institute of Shanghai Municipal Education Committee, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.03.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491716PMC
April 2019

Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice.

Acta Pharmacol Sin 2019 Apr 18. Epub 2019 Apr 18.

Center for Drug Safety Evaluation and Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.

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http://dx.doi.org/10.1038/s41401-019-0220-1DOI Listing
April 2019

Adolescent cocaine exposure enhances the GABAergic transmission in the prelimbic cortex of adult mice.

FASEB J 2019 Apr 29:fj201802192RR. Epub 2019 Apr 29.

Department of Human Anatomy and Histoembryology, School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, Nanjing, China.

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https://www.fasebj.org/doi/10.1096/fj.201802192RR
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http://dx.doi.org/10.1096/fj.201802192RRDOI Listing
April 2019

Genetic Load and Potential Mutational Meltdown in Cancer Cell Populations.

Mol Biol Evol 2019 03;36(3):541-552

Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, Beijing, China.

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http://dx.doi.org/10.1093/molbev/msy231DOI Listing
March 2019

Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice.

Acta Pharmacol Sin 2019 Mar 4. Epub 2019 Mar 4.

State Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, Nanjing, 210023, China.

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http://dx.doi.org/10.1038/s41401-018-0208-2DOI Listing
March 2019

Weak regulation of many targets is cumulatively powerful- a reply to Seitz on microRNA functionality.

Mol Biol Evol 2019 Mar 9. Epub 2019 Mar 9.

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.

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http://dx.doi.org/10.1093/molbev/msz055DOI Listing
March 2019

Tumorigenesis as the paradigm of quasi-neutral molecular evolution.

Mol Biol Evol 2019 Mar 26. Epub 2019 Mar 26.

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.

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https://academic.oup.com/mbe/advance-article/doi/10.1093/mol
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http://dx.doi.org/10.1093/molbev/msz075DOI Listing
March 2019

Enantioselective Radical Hydroacylation of Enals with α-Ketoacids Enabled by Photoredox/Amine Cocatalysis.

Org Lett 2019 02 29;21(4):913-916. Epub 2019 Jan 29.

State Key Laboratory of Analytical Chemistry for Life Science, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering , Nanjing University , Nanjing 210023 , China.

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http://dx.doi.org/10.1021/acs.orglett.8b03840DOI Listing
February 2019

Enhanced microbial degradation of benzo[a]pyrene by chemical oxidation.

Sci Total Environ 2019 Feb 3;653:1293-1300. Epub 2018 Nov 3.

Department of Environmental Science, Zhejiang University, Hangzhou, Zhejiang 310058, China; Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, Hangzhou, Zhejiang, 310058, China. Electronic address:

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http://dx.doi.org/10.1016/j.scitotenv.2018.10.444DOI Listing
February 2019

Understanding inter-organizational trust among integrated care service provider networks: A perspective on organizational asymmetries.

Health Policy 2018 Dec 11;122(12):1356-1363. Epub 2018 Sep 11.

Royal Berkshire NHS Foundation Trust, Reading, RG1 5AN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.healthpol.2018.09.003DOI Listing
December 2018

Measurement of the thermal conductivities of suspended MoS and MoSe by nanosecond ET-Raman without temperature calibration and laser absorption evaluation.

Nanoscale 2018 Dec;10(48):23087-23102

Department of Mechanical Engineering, Iowa State University, Ames, Iowa 50011, USA.

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http://dx.doi.org/10.1039/c8nr05641bDOI Listing
December 2018

Comparative Study of Ocular Pharmacokinetics of Gatifloxacin Between Continuous Lavage and Hourly Topical Instillation in Rabbits.

Cornea 2018 Nov;37(11):1457-1462

Department of Ophthalmology and Vision Science, University of Arizona College of Medicine, Tucson, AZ.

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http://dx.doi.org/10.1097/ICO.0000000000001712DOI Listing
November 2018

Farnesoid X receptor agonist obeticholic acid inhibits renal inflammation and oxidative stress during lipopolysaccharide-induced acute kidney injury.

Eur J Pharmacol 2018 Nov 6;838:60-68. Epub 2018 Sep 6.

Department of Toxicology, Anhui Medical University, Hefei, China; Laboratory of Environmental Toxicology, Hefei, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2018.09.009DOI Listing
November 2018

Vincamine as a GPR40 agonist improves glucose homeostasis in type 2 diabetic mice.

J Endocrinol 2018 Nov 1. Epub 2018 Nov 1.

X Shen, School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, Nanjing, China.

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http://dx.doi.org/10.1530/JOE-18-0432DOI Listing
November 2018

Novel technologies in utilization of byproducts of animal food processing: a review.

Crit Rev Food Sci Nutr 2018 Oct 4:1-11. Epub 2018 Oct 4.

b State Key Laboratory of Food Science and Technology , Jiangnan University , Wuxi , Jiangsu , China.

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http://dx.doi.org/10.1080/10408398.2018.1493428DOI Listing
October 2018

Synthesis and Application of Perylene-Embedded Benzoazoles for Small-Molecule Organic Solar Cells.

Org Lett 2018 10 8;20(20):6376-6379. Epub 2018 Oct 8.

Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergistic Innovation Center for Advanced Materials (SICAM) , Nanjing University of Posts & Telecommunications , 9 Wenyuan Road , Nanjing 210023 , China.

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http://pubs.acs.org/doi/10.1021/acs.orglett.8b02650
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http://dx.doi.org/10.1021/acs.orglett.8b02650DOI Listing
October 2018

Continuous Dropout.

IEEE Trans Neural Netw Learn Syst 2018 09 3;29(9):3926-3937. Epub 2017 Oct 3.

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https://ieeexplore.ieee.org/document/8057594/
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http://dx.doi.org/10.1109/TNNLS.2017.2750679DOI Listing
September 2018

Effect of ultrasound dielectric pretreatment on the oxidation resistance of vacuum-fried apple chips.

J Sci Food Agric 2018 Sep 3;98(12):4436-4444. Epub 2018 Apr 3.

Wuxi Delin Boat Equipment Co., Wuxi, Jiangsu, China.

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http://dx.doi.org/10.1002/jsfa.8966DOI Listing
September 2018

Vitamin D deficiency promotes prostatic hyperplasia in middle-age mice through exacerbating local inflammation.

J Steroid Biochem Mol Biol 2018 Sep 20;182:14-20. Epub 2018 Apr 20.

Department of Toxicology, Anhui Medical University, Hefei, China; Anhui Provincial Key Laboratory of Population Health and Aristogenics, Hefei, China; Laboratory of Environmental Toxicology, Anhui Medical University, Hefei, China. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2018.04.006DOI Listing
September 2018

miR-142-5p in Bone Marrow-Derived Mesenchymal Stem Cells Promotes Osteoporosis Involving Targeting Adhesion Molecule VCAM-1 and Inhibiting Cell Migration.

Biomed Res Int 2018 29;2018:3274641. Epub 2018 Mar 29.

Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA 5001, Australia.

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http://dx.doi.org/10.1155/2018/3274641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896351PMC
September 2018

The characteristics of beta 2-glycoprotein I-dependent anticardiolipin antibody and blood coagulation status in subjects with classical biological false-positive syphilis reactions.

Int Immunopharmacol 2018 Sep 10;62:132-138. Epub 2018 Jul 10.

Center of Clinical Laboratory, Zhongshan Hospital, Medical College of Xiamen University, Xiamen, Fujian Province, China; Institute of Infectious Disease, Medical College of Xiamen University, Xiamen, Fujian Province, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2018.05.033DOI Listing
September 2018

Death of new microRNA genes in via gradual loss of fitness advantages.

Genome Res 2018 09 26;28(9):1309-1318. Epub 2018 Jul 26.

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, Guangdong, China.

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http://dx.doi.org/10.1101/gr.233809.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120634PMC
September 2018

Photoredox-Catalyzed Intermolecular Remote C-H and C-C Vinylation via Iminyl Radicals.

Org Lett 2018 09 23;20(17):5523-5527. Epub 2018 Aug 23.

State Key Laboratory of Analytical Chemistry for Life Science, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering , Nanjing University , Nanjing 210023 , China.

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http://dx.doi.org/10.1021/acs.orglett.8b02540DOI Listing
September 2018

HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1α promoter.

Metabolism 2018 08 22;85:126-138. Epub 2018 Mar 22.

Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China; State Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing 210023, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00260495183008
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http://dx.doi.org/10.1016/j.metabol.2018.03.016DOI Listing
August 2018

[Clinical evaluation of short implants in atrophic posterior region].

Shanghai Kou Qiang Yi Xue 2018 Aug;27(4):401-406

Yantai Stomatological Hospital Affiliated to Binzhou Medical University. Yantai 264000, Shandong Province, China.

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August 2018

miR-29b regulates Ang II-induced EMT of rat renal tubular epithelial cells via targeting PI3K/AKT signaling pathway.

Int J Mol Med 2018 Jul 22;42(1):453-460. Epub 2018 Mar 22.

Department of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China.

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http://dx.doi.org/10.3892/ijmm.2018.3579DOI Listing
July 2018

Origin of Nontreponemal Antibodies During Treponema pallidum Infection: Evidence From a Rabbit Model.

J Infect Dis 2018 Jul;218(5):835-843

Zhongshan Hospital, Institute of Infectious Disease, Medical College of Xiamen University.

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http://dx.doi.org/10.1093/infdis/jiy241DOI Listing
July 2018

TSPA as a novel ATF6α translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice.

Biochem Biophys Res Commun 2018 05 9;499(4):948-953. Epub 2018 Apr 9.

CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; State Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing 210023, China.

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http://dx.doi.org/10.1016/j.bbrc.2018.04.025DOI Listing
May 2018

Vector Analysis of Cytoskeletal Structural Tension and the Mechanisms that Underpin Spectrin-Related Forces in Pyroptosis.

Antioxid Redox Signal 2018 May 30. Epub 2018 May 30.

4 Department of Biomedical Engineering, University of Alabama at Birmingham (UAB) , Birmingham, Alabama.

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http://dx.doi.org/10.1089/ars.2017.7366DOI Listing
May 2018

Discovery and structure-activity relationships study of thieno[2,3-b]pyridine analogues as hepatic gluconeogenesis inhibitors.

Eur J Med Chem 2018 May 24;152:307-317. Epub 2018 Apr 24.

Jiangsu Key Laboratory for Functional Substance of Chinese Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Stake Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.04.028DOI Listing
May 2018

Application of Data Provenance in Healthcare Analytics Software: Information Visualisation of User Activities.

AMIA Jt Summits Transl Sci Proc 2018 18;2017:263-272. Epub 2018 May 18.

King's College London, London, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961786PMC
May 2018

Dissemination and Molecular Characterization of at a Tertiary Referral Hospital in Xiamen City, China.

Biomed Res Int 2017 5;2017:1367179. Epub 2017 Jul 5.

Zhongshan Hospital, Xiamen University, Xiamen, Fujian Province 361004, China.

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http://dx.doi.org/10.1155/2017/1367179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516767PMC
April 2018

Transformation of tetrabromobisphenol A by Rhodococcus jostii RHA1: Effects of heavy metals.

Chemosphere 2018 Apr 28;196:206-213. Epub 2017 Dec 28.

State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing, Jiangsu Province, 210023, China. Electronic address:

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http://dx.doi.org/10.1016/j.chemosphere.2017.12.173DOI Listing
April 2018

Regulation of Large Number of Weak Targets-New Insights from Twin-microRNAs.

Genome Biol Evol 2018 04;10(5):1255-1264

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.

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http://dx.doi.org/10.1093/gbe/evy079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963297PMC
April 2018

Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy.

Neuropharmacology 2018 03 29;130:77-91. Epub 2017 Nov 29.

State Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, Nanjing 210023, China; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Key Laboratory of Drug Target and Drug for Degenerative Disease, Jiangsu Province, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00283908173056
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http://dx.doi.org/10.1016/j.neuropharm.2017.11.033DOI Listing
March 2018

Identification and characterization of evolutionarily conserved alternative splicing events in a mangrove genus Sonneratia.

Sci Rep 2018 Mar 13;8(1):4425. Epub 2018 Mar 13.

State Key Laboratory of Biocontrol and Guangdong Provincial Key Laboratory of Plant Resources, Sun Yat-sen University, Guangzhou, 510275, China.

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http://dx.doi.org/10.1038/s41598-018-22406-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849712PMC
March 2018

Design, synthesis and biological evaluation of LX2343 derivatives as neuroprotective agents for the treatment of Alzheimer's disease.

Eur J Med Chem 2018 Feb 2;145:622-633. Epub 2018 Jan 2.

Jiangsu Key Laboratory for Functional Substance of Chinese Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Stake Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, PR China; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.12.080DOI Listing
February 2018

ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP.

FEBS Lett 2018 02 13;592(4):599-609. Epub 2018 Feb 13.

College of Life Sciences, Shandong Agricultural University, Tai'an, Shandong, China.

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http://dx.doi.org/10.1002/1873-3468.12986DOI Listing
February 2018

Organophosphate pesticide in agricultural soils from the Yangtze River Delta of China: concentration, distribution, and risk assessment.

Environ Sci Pollut Res Int 2018 Jan 29;25(1):4-11. Epub 2016 Sep 29.

Department of Environmental Science, Zhejiang University, Hangzhou, Zhejiang, 310058, China.

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http://link.springer.com/10.1007/s11356-016-7664-3
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http://dx.doi.org/10.1007/s11356-016-7664-3DOI Listing
January 2018

Electrochemical aptamer-based nanosensor fabricated on single Au nanowire electrodes for adenosine triphosphate assay.

Biosens Bioelectron 2018 Jan 9;99:431-437. Epub 2017 Aug 9.

Anhui Key Laboratory of Chemo/Biosensing, College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2017.08.020DOI Listing
January 2018

Correlation between polymorphisms in toll-like receptor genes and the activity of hepatitis B virus among treatment-naïve patients: a case-control study in a Han Chinese population.

BMC Infect Dis 2018 01 10;18(1):28. Epub 2018 Jan 10.

Center of Clinical Laboratory, Zhongshan Hospital, Medical College of Xiamen University, 201-209 Hubin South Road, Siming District, Xiamen City, 361004, Fujian Province, People's Republic of China.

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-2943-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764005PMC
January 2018

Fusion or Not for Degenerative Lumbar Spinal Stenosis: A Meta-Analysis and Systematic Review.

Pain Physician 2018 01;21(1):1-8

The First Affiliated Hospital of Chongqing Medical University Dept. of Orthopaedics, Chongqing, China.

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January 2018

Knockdown of MPP8 suppresses cell proliferation via regulation of HOXA5 in non-small cell lung cancer cells.

Cell Mol Biol (Noisy-le-grand) 2018 Jan 31;64(1):27-31. Epub 2018 Jan 31.

Department of Pathology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou Fujian 350014, China.

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https://www.cellmolbiol.org/index.php/CMB/article/view/1573
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http://dx.doi.org/10.14715/cmb/2018.64.1.6DOI Listing
January 2018

Risk factors and molecular epidemiology of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in Xiamen, China.

J Glob Antimicrob Resist 2017 12 23;11:23-27. Epub 2017 Aug 23.

Zhongshan Hospital, Medical College of Xiamen University, Xiamen, China; Xiamen Zhongshan Hospital, Fujian Medical University, Xiamen, China. Electronic address:

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http://dx.doi.org/10.1016/j.jgar.2017.04.015DOI Listing
December 2017

Weak Regulation of Many Targets Is Cumulatively Powerful-An Evolutionary Perspective on microRNA Functionality.

Mol Biol Evol 2017 Dec;34(12):3041-3046

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.

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http://dx.doi.org/10.1093/molbev/msx260DOI Listing
December 2017

Allosteric inhibitor remotely modulates the conformation of the orthestric pockets in mutant IDH2/R140Q.

Sci Rep 2017 Nov 28;7(1):16458. Epub 2017 Nov 28.

Key Laboratory of Drug Targets and Drug Leads for Degenerative Diseases, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.

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http://dx.doi.org/10.1038/s41598-017-16427-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705638PMC
November 2017

Vitamin D deficiency impairs testicular development and spermatogenesis in mice.

Reprod Toxicol 2017 10 26;73:241-249. Epub 2017 Jun 26.

Department of Toxicology, Anhui Medical University, Hefei, China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei, China; Laboratory of Environmental Toxicology, Anhui Medical University, Hefei, China. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2017.06.047DOI Listing
October 2017

Vitamin D deficiency impairs neurobehavioral development in male mice.

Physiol Behav 2017 Oct 9;179:333-339. Epub 2017 Jul 9.

Department of Toxicology, Anhui Medical University, Hefei, China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei, China. Electronic address:

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http://dx.doi.org/10.1016/j.physbeh.2017.07.017DOI Listing
October 2017

Identifying the Crystalline Orientation of Black Phosphorus by Using Optothermal Raman Spectroscopy.

Chemphyschem 2017 Oct 25;18(20):2828-2834. Epub 2017 Aug 25.

Department of Mechanical Engineering, Iowa State University, 2025 Black Engineering Building, Ames, IA, 50010, USA.

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http://dx.doi.org/10.1002/cphc.201700788DOI Listing
October 2017

Discovery of cycloalkyl-fused N-thiazol-2-yl-benzamides as tissue non-specific glucokinase activators: Design, synthesis, and biological evaluation.

Eur J Med Chem 2017 Oct 25;139:128-152. Epub 2017 Jul 25.

Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.07.051DOI Listing
October 2017

DMT efficiently inhibits hepatic gluconeogenesis by regulating the Gαq signaling pathway.

J Mol Endocrinol 2017 08 21;59(2):151-169. Epub 2017 Jun 21.

Key Laboratory of Receptor ResearchShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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http://dx.doi.org/10.1530/JME-17-0121DOI Listing
August 2017

LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy.

Acta Pharmacol Sin 2017 Aug 26;38(8):1104-1119. Epub 2017 Jun 26.

CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

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http://dx.doi.org/10.1038/aps.2016.128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547549PMC
August 2017

The clinical characteristics of posterior reversible encephalopathy syndrome in patients with chronic renal failure.

Exp Ther Med 2017 Jul 8;14(1):881-887. Epub 2017 Jun 8.

Department of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China.

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http://dx.doi.org/10.3892/etm.2017.4570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488738PMC
July 2017

Synthesis and glucose-stimulate insulin secretion (GSIS) evaluation of vindoline derivatives.

Bioorg Med Chem Lett 2017 03 28;27(5):1316-1318. Epub 2016 Sep 28.

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.09.064DOI Listing
March 2017

Single gold nanowire electrodes and single Pt@Au nanowire electrodes: electrochemistry and applications.

Chem Commun (Camb) 2017 Mar;53(19):2850-2853

Anhui Key Laboratory of Chemo/Biosensing, College of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241000, P. R. China.

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http://xlink.rsc.org/?DOI=C6CC09854A
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http://dx.doi.org/10.1039/c6cc09854aDOI Listing
March 2017

Low vitamin D status is associated with inflammation in patients with prostate cancer.

Oncotarget 2017 Mar;8(13):22076-22085

Department of Urology, Second Affiliated Hospital, Anhui Medical University, Hefei 230022, China.

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http://dx.doi.org/10.18632/oncotarget.16195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400647PMC
March 2017

Aggregation Reverses the Carrier Effects of TiO Nanoparticles on Cadmium Accumulation in the Waterflea Daphnia magna.

Environ Sci Technol 2017 01 30;51(2):932-939. Epub 2016 Dec 30.

State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University , Nanjing, Jiangsu Province 210023, China.

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http://dx.doi.org/10.1021/acs.est.6b03951DOI Listing
January 2017

, a Transcriptionally Active Ty1/Copia-Like Retrotransposon Has Colonized the Genome of through Horizontal Transfer.

Front Plant Sci 2017 24;8:45. Epub 2017 Jan 24.

State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Plant Resources School of Life Sciences, Key Laboratory of Biodiversity Dynamics and Conservation of Guangdong Higher Education Institutes, Sun Yat-sen University Guangzhou, China.

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http://journal.frontiersin.org/article/10.3389/fpls.2017.000
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http://dx.doi.org/10.3389/fpls.2017.00045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258746PMC
January 2017

Excited State Modulation for Organic Afterglow: Materials and Applications.

Adv Mater 2016 Dec 16;28(45):9920-9940. Epub 2016 Sep 16.

Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University (Nanjing Tech), Nanjing, 211816, P. R. China.

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http://dx.doi.org/10.1002/adma.201602604DOI Listing
December 2016

Isolation, characterization, and marker utility of KCRE1, a transcriptionally active Ty1/copia retrotransposon from Kandelia candel.

Mol Genet Genomics 2016 Dec 4;291(6):2031-2042. Epub 2016 Aug 4.

State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Plant Resources and Key Laboratory of Biodiversity Dynamics and Conservation of Guangdong Higher Education Institutes, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, Guangdong, People's Republic of China.

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http://dx.doi.org/10.1007/s00438-016-1237-5DOI Listing
December 2016

Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis.

Cell Res 2016 Dec 22;26(12):1330-1344. Epub 2016 Nov 22.

Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1038/cr.2016.136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143422PMC
December 2016

Effect of 1,25(OH)D on transdifferentiation of rat renal tubular epithelial cells induced by high glucose.

Biomed Rep 2016 Dec 1;5(6):699-704. Epub 2016 Nov 1.

Department of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China.

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http://dx.doi.org/10.3892/br.2016.800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228064PMC
December 2016

Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening.

Eur J Med Chem 2016 Nov 11;124:981-991. Epub 2016 Oct 11.

Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.

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http://dx.doi.org/10.1016/j.ejmech.2016.10.019DOI Listing
November 2016

Transcriptome sequencing reveals genetic mechanisms underlying the transition between the laying and brooding phases and gene expression changes associated with divergent reproductive phenotypes in chickens.

Mol Biol Rep 2016 Sep 7;43(9):977-89. Epub 2016 Jul 7.

Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, 510642, Guangdong, People's Republic of China.

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http://dx.doi.org/10.1007/s11033-016-4033-8DOI Listing
September 2016

Calcitriol inhibits tumor necrosis factor alpha and macrophage inflammatory protein-2 during lipopolysaccharide-induced acute lung injury in mice.

Steroids 2016 08 20;112:81-7. Epub 2016 May 20.

The Second Affiliated Hospital, Anhui Medical University, Hefei, China. Electronic address:

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http://dx.doi.org/10.1016/j.steroids.2016.05.005DOI Listing
August 2016

Synthesis and decreasing Aβ content evaluation of arctigenin-4-yl carbamate derivatives.

Bioorg Med Chem Lett 2016 07 10;26(13):2988-2991. Epub 2016 May 10.

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 201203, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.05.028DOI Listing
July 2016

TiO2 Nanoparticle Uptake by the Water Flea Daphnia magna via Different Routes is Calcium-Dependent.

Environ Sci Technol 2016 07 8;50(14):7799-807. Epub 2016 Jul 8.

State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University , Nanjing, Jiangsu Province 210023, China.

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http://pubs.acs.org/doi/10.1021/acs.est.6b01645
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http://dx.doi.org/10.1021/acs.est.6b01645DOI Listing
July 2016

Small RNA transcriptomes of mangroves evolve adaptively in extreme environments.

Sci Rep 2016 06 9;6:27551. Epub 2016 Jun 9.

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Key Laboratory of Biodiversity Dynamics and Conservation of Guangdong Higher Education Institutes, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, Guangdong, China.

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http://dx.doi.org/10.1038/srep27551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899726PMC
June 2016

Thermal conductivity of giant mono- to few-layered CVD graphene supported on an organic substrate.

Nanoscale 2016 May 29;8(19):10298-309. Epub 2016 Apr 29.

2010 Black Engineering Building, Department of Mechanical Engineering, Iowa State University, Ames, IA 50011, USA.

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http://dx.doi.org/10.1039/c6nr02258hDOI Listing
May 2016

Facile synthesis of 3D porous thermally exfoliated g-C3N4 nanosheet with enhanced photocatalytic degradation of organic dye.

J Colloid Interface Sci 2016 Apr 22;468:211-219. Epub 2016 Jan 22.

Chongqing Academy of Science and Technology, Chongqing 401123, China.

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http://dx.doi.org/10.1016/j.jcis.2016.01.048DOI Listing
April 2016

Corrigendum to "Association between cigarette smoking and parkinson's disease: A meta-analysis" [Archives of gerontology and geriatrics, 61 (2015) 510-516].

Arch Gerontol Geriatr 2016 Jul-Aug;65:260. Epub 2016 Apr 15.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China. Electronic address:

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http://dx.doi.org/10.1016/j.archger.2016.04.007DOI Listing
April 2016

Association between cigarette smoking and Parkinson's disease: A meta-analysis.

Arch Gerontol Geriatr 2015 Nov-Dec;61(3):510-6. Epub 2015 Aug 4.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China. Electronic address:

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http://dx.doi.org/10.1016/j.archger.2015.08.004DOI Listing
February 2016

Calcitriol inhibits bleomycin-induced early pulmonary inflammatory response and epithelial-mesenchymal transition in mice.

Toxicol Lett 2016 Jan 28;240(1):161-71. Epub 2015 Oct 28.

Department of Toxicology, Anhui Medical University, Hefei 230032, China. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2015.10.022DOI Listing
January 2016

Cadmium toxicity to Microcystis aeruginosa PCC 7806 and its microcystin-lacking mutant.

PLoS One 2015 15;10(1):e0116659. Epub 2015 Jan 15.

State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing, Jiangsu Province, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116659PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295860PMC
December 2015

Thermal Conductivity of Ultrahigh Molecular Weight Polyethylene Crystal: Defect Effect Uncovered by 0 K Limit Phonon Diffusion.

ACS Appl Mater Interfaces 2015 Dec 4;7(49):27279-88. Epub 2015 Dec 4.

Department of Mechanical Engineering, Iowa State University , 2010 Black Engineering Building, Ames, Iowa 50011, United States.

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http://dx.doi.org/10.1021/acsami.5b08578DOI Listing
December 2015

Discovery and SAR study of 3-(tert-butyl)-4-hydroxyphenyl benzoate and benzamide derivatives as novel farnesoid X receptor (FXR) antagonists.

Bioorg Med Chem 2015 Oct 20;23(19):6427-36. Epub 2015 Aug 20.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, PR China; Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.08.021DOI Listing
October 2015

Small molecule TBTC as a new selective retinoid X receptor α agonist improves behavioral deficit in Alzheimer's disease model mice.

Eur J Pharmacol 2015 Sep 27;762:202-13. Epub 2015 May 27.

School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2015.05.050DOI Listing
September 2015

Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells.

Acta Pharmacol Sin 2015 Sep 17;36(9):1126-36. Epub 2015 Aug 17.

CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

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http://www.nature.com/articles/aps201556
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http://dx.doi.org/10.1038/aps.2015.56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561973PMC
September 2015

Vitamin D3 pretreatment alleviates renal oxidative stress in lipopolysaccharide-induced acute kidney injury.

J Steroid Biochem Mol Biol 2015 Aug 23;152:133-41. Epub 2015 May 23.

The Second Affiliated Hospital, Anhui Medical University, Hefei, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09600760150014
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http://dx.doi.org/10.1016/j.jsbmb.2015.05.009DOI Listing
August 2015

Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor α (FXRα) in Stabilizing the Homodimerization of the Receptor.

J Biol Chem 2015 Aug 22;290(32):19888-99. Epub 2015 Jun 22.

From the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China,

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http://dx.doi.org/10.1074/jbc.M114.630475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528148PMC
August 2015

The defect level and ideal thermal conductivity of graphene uncovered by residual thermal reffusivity at the 0 K limit.

Nanoscale 2015 Jun 18;7(22):10101-10. Epub 2015 May 18.

Department of Mechanical Engineering, Iowa State University, Ames, IA 50011, USA.

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http://xlink.rsc.org/?DOI=C5NR02012C
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http://dx.doi.org/10.1039/c5nr02012cDOI Listing
June 2015

Impact of Surface-Bound Small Molecules on the Thermoelectric Property of Self-Assembled Ag₂Te Nanocrystal Thin Films.

Nano Lett 2015 Jun 27;15(6):3748-56. Epub 2015 May 27.

†School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian, Liaoning 116024, People's Republic of China.

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http://dx.doi.org/10.1021/acs.nanolett.5b00255DOI Listing
June 2015

Temperature dependence of electrical and thermal conduction in single silver nanowire.

Sci Rep 2015 Jun 2;5:10718. Epub 2015 Jun 2.

1] Department of Mechanical Engineering, 2010 Black Engineering Building, Iowa State University, Ames, Iowa, 50011, USA [2] School of Environmental and Municipal Engineering, Qingdao Technological University, Qingdao, Shandong, 266033, P.R. China.

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http://dx.doi.org/10.1038/srep10718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451791PMC
June 2015

In Silico Estimation of Chemical Carcinogenicity with Binary and Ternary Classification Methods.

Mol Inform 2015 04 27;34(4):228-35. Epub 2015 Mar 27.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China phone: +86-21-6425-1052; fax: +86-21-6425-1033.

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http://dx.doi.org/10.1002/minf.201400127DOI Listing
April 2015

BBT improves glucose homeostasis by ameliorating β-cell dysfunction in type 2 diabetic mice.

J Endocrinol 2015 Mar 8;224(3):327-41. Epub 2015 Jan 8.

Key Laboratory of Receptor ResearchShanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, ChinaCollege of Life and Environmental SciencesShanghai Normal University, 100 Guilin Road, Shanghai 200234, ChinaDepartment of PharmacologyChina Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China

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https://joe.bioscientifica.com/view/journals/joe/224/3/327.x
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http://dx.doi.org/10.1530/JOE-14-0721DOI Listing
March 2015

FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach.

Sci Rep 2015 Jan 29;5:8114. Epub 2015 Jan 29.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.

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http://www.nature.com/articles/srep08114
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http://dx.doi.org/10.1038/srep08114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310094PMC
January 2015