Xiyuan Bai

Measurable genomic changes in subsp. after long-term adaptation in and reduced persistence in macrophages.

Authors:

Nabeeh A Hasan Grant J Norton Ravleen Virdi L Elaine Epperson Charmie K Vang Brandon Hellbusch Xiyuan Bai Edward D Chan Michael Strong Jennifer R Honda

J Bacteriol 2021 Jan 11. Epub 2021 Jan 11.

Center for Genes, Environment and Health, National Jewish Health, Denver, Colorado, USA

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January 2021

Further evidence that cigarette smoke and nicotine compromise host immunity against tuberculosis (invited editorial).

Authors:

Edward D Chan Xiyuan Bai

Tuberculosis (Edinb) 2020 Dec 2:102035. Epub 2020 Dec 2.

Pulmonary Section, Rocky Mountain Regional Veterans Affairs Medical Center, Aurora, CO, USA; Department of Academic Affairs, National Jewish Health, Denver, CO, USA; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address:

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December 2020

Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19.

Authors:

Xiyuan Bai Joseph Hippensteel Alida Leavitt James P Maloney David Beckham Cindy Garcia Qing Li Brian M Freed Diane Ordway Robert A Sandhaus Edward D Chan

Med Hypotheses 2021 Jan 12;146:110394. Epub 2020 Nov 12.

Rocky Mountain Regional Veterans Affairs Medical Center, Aurora, CO, USA; Departments of Academic Affairs and Medicine, National Jewish Health, Denver, CO, USA; Division of Pulmonary Sciences and Critical Care Medicine, USA. Electronic address:

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January 2021

Differential Responses by Human Macrophages to Infection With and Non-tuberculous Mycobacteria.

Authors:

Zhihong Feng Xiyuan Bai Tao Wang Cindy Garcia An Bai Li Li Jennifer R Honda Xiuhong Nie Edward D Chan

Front Microbiol 2020 7;11:116. Epub 2020 Feb 7.

National Jewish Health, Denver, CO, United States.

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February 2020

Transgenic mice expressing human IL-32 develop adipokine profiles resembling those of obesity-induced metabolic changes.

Authors:

Michelle S M A Damen Dov Ballak Zackary Sapinsley Xiyuan Bai Edward D Chan Douglas R Seals Calin D Popa Leo A B Joosten

Cytokine 2020 01 6;125:154793. Epub 2019 Aug 6.

Department of Internal Medicine and Radboud Centre for Infectious Diseases (RCI), 6525GA Nijmegen, the Netherlands.

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January 2020

Alpha-1-Antitrypsin Enhances Primary Human Macrophage Immunity Against Non-tuberculous Mycobacteria.

Authors:

Xiyuan Bai An Bai Jennifer R Honda Charles Eichstaedt Ariel Musheyev Zhihong Feng Gwen Huitt Ronald Harbeck Beata Kosmider Robert A Sandhaus Edward D Chan

Front Immunol 2019 26;10:1417. Epub 2019 Jun 26.

Division of Pulmonary, Critical Care, and Sleep Medicine, National Jewish Health, Denver, CO, United States.

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October 2020

Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis.

Authors:

Elliot W Kim Avelino De Leon Zhichun Jiang Roxana A Radu Adrian R Martineau Edward D Chan Xiyuan Bai Wen-Lin Su Dennis J Montoya Robert L Modlin Philip T Liu

mSphere 2019 06 5;4(3). Epub 2019 Jun 5.

Division of Dermatology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA

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June 2019

Epidemiologic Evidence of and Potential Mechanisms by Which Second-Hand Smoke Causes Predisposition to Latent and Active Tuberculosis.

Authors:

Xiyuan Bai Shanae L Aerts Deepshikha Verma Diane J Ordway Edward D Chan

Immune Netw 2018 Jun 26;18(3):e22. Epub 2018 Jun 26.

Department of Medicine, Denver Veterans Affairs Medical Center, University of Colorado Anschutz Medical Center, Denver, CO 80045, USA.

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June 2018

Acquired and genetic host susceptibility factors and microbial pathogenic factors that predispose to nontuberculous mycobacterial infections.

Authors:

Jennifer R Honda Scott Alper Xiyuan Bai Edward D Chan

Curr Opin Immunol 2018 10 21;54:66-73. Epub 2018 Jun 21.

Medicine and Academic Affairs, National Jewish Health, Denver, CO, United States; Department of Medicine, Denver Veterans Affairs Medical Center, Denver, CO, United States; Division of Pulmonary Sciences and Critical Care Medicine, United States. Electronic address:

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October 2018

Human Interleukin-32γ Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice.

Authors:

Rodrigo Saar Gomes Muriel Vilela Teodoro Silva Jéssica Cristina Dos Santos Christine van Linge Juliana Machado Reis Mauro Martins Teixeira Sebastião Alves Pinto Miriam Leandro Dorta Xiyuan Bai Edward D Chan Charles A Dinarello Milton Adriano Pelli Oliveira Leo A B Joosten Fátima Ribeiro-Dias

Infect Immun 2018 05 23;86(5). Epub 2018 Apr 23.

Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Brazil

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May 2018

Elucidating the Pathogenesis of Nontuberculous Mycobacterial Lung Disease: Lesson from the Six Blind Men and the Elephant.

Authors:

Jennifer R Honda Xiyuan Bai Edward D Chan

Am J Respir Cell Mol Biol 2018 02;58(2):142-143

1 National Jewish Health Denver, Colorado and.

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February 2018

Use of Digital Droplet PCR to Detect DNA in Whole Blood-Derived DNA Samples from Patients with Pulmonary and Extrapulmonary Tuberculosis.

Authors:

Jiaru Yang Xinlin Han Aihua Liu Xiyuan Bai Cuiping Xu Fukai Bao Shi Feng Lvyan Tao Mingbiao Ma Yun Peng

Front Cell Infect Microbiol 2017 11;7:369. Epub 2017 Aug 11.

Yunnan Key Laboratory for Tropical Infectious DiseasesKunming, China.

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April 2018

IL-32-induced Inflammatory Cytokines Are Selectively Suppressed by α1-antitrypsin in Mouse Bone Marrow Cells.

Authors:

Siyoung Lee Dong-Ki Choi Areum Kwak Sinae Kim Tam Thanh Nguyen Gaae Gil Eunhye Kim Kwang Ha Yoo In Ae Kim Youngmin Lee Hyunjhung Jhun Edward D Chan Xiyuan Bai Hyunwoo Kim Yong-Sung Kim Soohyun Kim

Immune Netw 2017 Apr 20;17(2):116-120. Epub 2017 Apr 20.

Laboratory of Cytokine Immunology, Department of Biomedical Science and Technology, Konkuk University, Seoul 05029, Korea.

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April 2017

Nicotine Impairs Macrophage Control of Mycobacterium tuberculosis.

Authors:

Xiyuan Bai Jerry A Stitzel An Bai Cristian A Zambrano Matthew Phillips Philippa Marrack Edward D Chan

Am J Respir Cell Mol Biol 2017 09;57(3):324-333

1 Department of Medicine, Denver Veterans Affairs Medical Center, Denver, Colorado.

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September 2017

Curcumin enhances human macrophage control of Mycobacterium tuberculosis infection.

Authors:

Xiyuan Bai Rebecca E Oberley-Deegan An Bai Alida R Ovrutsky William H Kinney Michael Weaver Gong Zhang Jennifer R Honda Edward D Chan

Respirology 2016 Jul 24;21(5):951-7. Epub 2016 Mar 24.

Department of Medicine, Denver Veterans Affairs Medical Center, Denver, USA.

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July 2016

The role of interleukin-32 against tuberculosis.

Authors:

Xiyuan Bai Charles A Dinarello Edward D Chan

Cytokine 2015 Dec 3;76(2):585-587. Epub 2015 Jul 3.

Denver Veterans Affairs Medical Center, 1055 Clermont St, Denver, CO 80206, United States; Departments of Medicine and Academic Affairs, D509, Neustadt Building, National Jewish Health, 1400 Jackson St, Denver, CO 80206, United States; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver Anschutz Medical Campus, 12700 East 19th Avenue, Aurora, CO 80045-2539, United States. Electronic address:

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December 2015

Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids.

Authors:

Jennifer R Honda Tamara Hess Kenneth C Malcolm Alida R Ovrutsky Xiyuan Bai Vida R Irani Karen M Dobos Edward D Chan Sonia C Flores

PLoS One 2015 18;10(5):e0126994. Epub 2015 May 18.

Department of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.

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April 2016

Caspase-3-independent apoptotic pathways contribute to interleukin-32γ-mediated control of Mycobacterium tuberculosis infection in THP-1 cells.

Authors:

Xiyuan Bai William H Kinney Wen-Lin Su An Bai Alida R Ovrutsky Jennifer R Honda Mihai G Netea Marcela Henao-Tamayo Diane J Ordway Charles A Dinarello Edward D Chan

BMC Microbiol 2015 Feb 21;15:39. Epub 2015 Feb 21.

Department of Medicine, Denver Veterans Affairs Medical Center, Denver, CO, USA.

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February 2015

Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis.

Proc Natl Acad Sci U S A 2015 Apr 27;112(16):5111-6. Epub 2015 Mar 27.

Denver Veterans Affairs Medical Center, Denver, CO 80206; Departments of Medicine and Academic Affairs, Divisions of Pulmonary Sciences and Critical Care Medicine and

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April 2015

Epidemiologic link between tuberculosis and cigarette/biomass smoke exposure: Limitations despite the vast literature.

Authors:

Raju Bishwakarma William H Kinney Jennifer R Honda Jenny Mya Matthew J Strand Avani Gangavelli Xiyuan Bai Diane J Ordway Michael D Iseman Edward D Chan

Respirology 2015 May 25;20(4):556-68. Epub 2015 Mar 25.

Departments of Medicine and Academic Affairs, National Jewish Health, Denver, Colorado, USA; Department of Medicine, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.

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May 2015

Tobacco exposure and susceptibility to tuberculosis: is there a smoking gun?

Authors:

Edward D Chan William H Kinney Jennifer R Honda Raju Bishwakarma Avani Gangavelli Jenny Mya Xiyuan Bai Diane J Ordway

Tuberculosis (Edinb) 2014 Dec 28;94(6):544-50. Epub 2014 Sep 28.

Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, 1682 Campus Delivery, Fort Collins, CO 80523, USA.

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December 2014

A surface with a biomimetic micropattern reduces colonization of Mycobacterium abscessus.

Authors:

Eun Kim William H Kinney Alida R Ovrutsky Danthy Vo Xiyuan Bai Jennifer R Honda Grace Marx Emily Peck Leslie Lindberg Joseph O Falkinham Rhea M May Edward D Chan

FEMS Microbiol Lett 2014 Nov 9;360(1):17-22. Epub 2014 Sep 9.

Department of Medicine and Academic Affairs, National Jewish Health, Denver, CO, USA.

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November 2014

Patients with non-tuberculous mycobacterial lung disease have elevated transforming growth factor-beta following ex vivo stimulation of blood with live Mycobacterium intracellulare.

Authors:

Alida R Ovrutsky Patricia A Merkel Eric Schonteich Xiyuan Bai William Kinney Michael D Iseman Marinka Kartalija Vijaya Knight Edward D Chan

Scand J Infect Dis 2013 Sep 1;45(9):711-4. Epub 2013 Jul 1.

Denver Veterans Affairs Medical Center, Colorado, USA.

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September 2013

Inhibition of nuclear factor-kappa B activation decreases survival of Mycobacterium tuberculosis in human macrophages.

Authors:

Xiyuan Bai Nicole E Feldman Kathryn Chmura Alida R Ovrutsky Wen-Lin Su Laura Griffin Dohun Pyeon Mischa T McGibney Matthew J Strand Mari Numata Seiji Murakami Loretta Gaido Jennifer R Honda William H Kinney Rebecca E Oberley-Deegan Dennis R Voelker Diane J Ordway Edward D Chan

PLoS One 2013 25;8(4):e61925. Epub 2013 Apr 25.

Department of Medicine, Denver Veterans Affairs Medical Center, Denver, Colorado, United States of America.

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November 2013

Cooccurrence of free-living amoebae and nontuberculous Mycobacteria in hospital water networks, and preferential growth of Mycobacterium avium in Acanthamoeba lenticulata.

Authors:

Alida R Ovrutsky Edward D Chan Marinka Kartalija Xiyuan Bai Mary Jackson Sara Gibbs Joseph O Falkinham Michael D Iseman Paul R Reynolds Gerald McDonnell Vincent Thomas

Appl Environ Microbiol 2013 May 8;79(10):3185-92. Epub 2013 Mar 8.

National Jewish Health, Denver, CO, USA.

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May 2013

Patients with nontuberculous mycobacterial lung disease exhibit unique body and immune phenotypes.

Authors:

Marinka Kartalija Alida R Ovrutsky Courtney L Bryan Gregory B Pott Giamila Fantuzzi Jacob Thomas Matthew J Strand Xiyuan Bai Preveen Ramamoorthy Micol S Rothman Vijaya Nagabhushanam Michael McDermott Adrah R Levin Ashley Frazer-Abel Patricia C Giclas Judith Korner Michael D Iseman Leland Shapiro Edward D Chan

Am J Respir Crit Care Med 2013 Jan 9;187(2):197-205. Epub 2012 Nov 9.

Division of Infectious Diseases, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.

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January 2013

IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease.

Authors:

Xiyuan Bai Alida R Ovrutsky Marinka Kartalija Kathryn Chmura Amanda Kamali Jennifer R Honda Rebecca E Oberley-Deegan Charles A Dinarello James D Crapo Ling-Yi Chang Edward D Chan

Int Immunol 2011 Nov 27;23(11):679-91. Epub 2011 Oct 27.

Department of Medicine, Denver Veterans Affairs Medical Center, Denver, CO 80220, USA.

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November 2011

A trojan horse strategy to deliver amikacin to mycobacterial granulomas.

Authors:

Alida R Ovrutsky Marinka Kartalija Xiyuan Bai Edward D Chan

Am J Respir Crit Care Med 2011 Oct;184(7):860; author reply 860-1

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October 2011

Cigarette smoke increases susceptibility to tuberculosis--evidence from in vivo and in vitro models.

Authors:

Shaobin Shang Diane Ordway Marcela Henao-Tamayo Xiyuan Bai Rebecca Oberley-Deegan Crystal Shanley Ian M Orme Stephanie Case Maisha Minor David Ackart Laurel Hascall-Dove Alida R Ovrutsky Pitchaimani Kandasamy Dennis R Voelker Cherie Lambert Brian M Freed Michael D Iseman Randall J Basaraba Edward D Chan

J Infect Dis 2011 May 28;203(9):1240-8. Epub 2011 Feb 28.

Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, USA.

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May 2011

Mycobacterium tuberculosis increases IP-10 and MIG protein despite inhibition of IP-10 and MIG transcription.

Authors:

Xiyuan Bai Kathryn Chmura Alida R Ovrutsky Russell P Bowler Robert I Scheinman Rebecca E Oberley-Deegan Haiying Liu Shaobin Shang Diane Ordway Edward D Chan

Tuberculosis (Edinb) 2011 Jan 16;91(1):26-35. Epub 2010 Dec 16.

Denver Veterans Affair Medical Center, University of Colorado Denver, Aurora, CO, United States.

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January 2011

An oxidative environment promotes growth of Mycobacterium abscessus.

Authors:

Rebecca E Oberley-Deegan Brittany W Rebits Michael R Weaver Angela K Tollefson Xiyuan Bai Mischa McGibney Alida R Ovrutsky Edward D Chan James D Crapo

Free Radic Biol Med 2010 Dec 31;49(11):1666-73. Epub 2010 Aug 31.

Department of Medicine, National Jewish Health, Denver, CO 80206, USA.

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December 2010

IL-32 is a host protective cytokine against Mycobacterium tuberculosis in differentiated THP-1 human macrophages.

Authors:

Xiyuan Bai Soo-Hyun Kim Tania Azam Mischa T McGibney Hua Huang Charles A Dinarello Edward D Chan

J Immunol 2010 Apr 26;184(7):3830-40. Epub 2010 Feb 26.

Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver at Anschutz Medical Center, Denver, CO 80045, USA.

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April 2010

Host immune response to rapidly growing mycobacteria, an emerging cause of chronic lung disease.

Authors:

Edward D Chan Xiyuan Bai Marinka Kartalija Ian M Orme Diane J Ordway

Am J Respir Cell Mol Biol 2010 Oct 15;43(4):387-93. Epub 2010 Jan 15.

Division of Mycobacterial and Respiratory Infections, National Jewish Health, Denver, CO 80206, USA.

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October 2010

Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta.

Authors:

Jaewoo Hong Suyoung Bae Youngsun Kang Doyoung Yoon Xiyuan Bai Edward D Chan Tania Azam Charles A Dinarello Siyoung Lee Erk Her Gyujin Rho Soohyun Kim

Cytokine 2010 Feb 31;49(2):171-6. Epub 2009 Oct 31.

Laboratory of Cytokine Immunology, Medical Immunology Center, Institute of Biomedical Science and Technology, Konkuk University 1 Hwayang dong, Gwangjin-gu, Seoul 143-701, Republic of Korea.

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February 2010

Suppression of IFNgamma+mycobacterial lipoarabinomannan-induced NO by IL-4 is due to decreased IRF-1 expression.

Authors:

Kristin R Morris Ryan D Lutz Xiyuan Bai Mischa T McGibney Danielle Cook Diane Ordway Edward D Chan

Tuberculosis (Edinb) 2009 Jul 24;89(4):294-303. Epub 2009 Jun 24.

Department of Medicine, University of Colorado Health Sciences Center, Denver, CO, USA.

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July 2009

Identification and characterization of a novel testis-specific gene CKT2, which encodes a substrate for protein kinase CK2.

Authors:

Xiyuan Bai Derek Silvius Edward D Chan Denise Escalier Shaun Xin Xu

Nucleic Acids Res 2009 May 9;37(8):2699-711. Epub 2009 Mar 9.

McLaughlin Research Institute for Biomedical Science, Great Falls, MT 59405, USA.

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May 2009

Induction of IL-8 by Mycoplasma pneumoniae membrane in BEAS-2B cells.

Authors:

Kathryn Chmura Xiyuan Bai Mari Nakamura Pitchaimani Kandasamy Mischa McGibney Koji Kuronuma Hiroki Mitsuzawa Dennis R Voelker Edward D Chan

Am J Physiol Lung Cell Mol Physiol 2008 Jul 16;295(1):L220-30. Epub 2008 May 16.

Department of Medicin, National Jewish Medical and Research Center, Denver, Colorado 80206, USA.

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July 2008

Animal model of Mycobacterium abscessus lung infection.

Authors:

Diane Ordway Marcela Henao-Tamayo Erin Smith Crystal Shanley Marisa Harton Jolynn Troudt Xiyuan Bai Randall J Basaraba Ian M Orme Edward D Chan

J Leukoc Biol 2008 Jun 29;83(6):1502-11. Epub 2008 Feb 29.

Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523-1682, USA.

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June 2008