Xiuqing Zhang

Xiuqing Zhang

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Xiuqing Zhang

Publications by authors named "Xiuqing Zhang"

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Selection of potential cytokeratin-18 monoclonal antibodies following IGH repertoire evaluation in mice.

J Immunol Methods 2019 Nov 14;474:112647. Epub 2019 Aug 14.

BGI-Shenzhen, Shenzhen 518083, China; China National GeneBank, BGI-Shenzhen, Shenzhen 518120, China; Complete Genomics, Inc., 2904 Orchard Parkway, San Jose, CA 95134, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2019.112647DOI Listing
November 2019

D-GPM: A Deep Learning Method for Gene Promoter Methylation Inference.

Genes (Basel) 2019 10 14;10(10). Epub 2019 Oct 14.

Department of Computer Science, City University of Hong Kong, Kowloon 999077, Hong Kong.

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http://dx.doi.org/10.3390/genes10100807DOI Listing
October 2019

Re-designing ferritin nanocages for mercuric ion detection.

Analyst 2019 Sep;144(19):5890-5897

Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing Key Laboratory of Functional Food from Plant Resources, Beijing, 100083, China.

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http://dx.doi.org/10.1039/c9an01110bDOI Listing
September 2019

An overview and metanalysis of machine and deep learning-based CRISPR gRNA design tools.

RNA Biol 2019 Sep 27:1-10. Epub 2019 Sep 27.

BGI-Shenzhen , Shenzhen , China.

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http://dx.doi.org/10.1080/15476286.2019.1669406DOI Listing
September 2019

Germline-Encoded TCR-MHC Contacts Promote TCR V Gene Bias in Umbilical Cord Blood T Cell Repertoire.

Front Immunol 2019 30;10:2064. Epub 2019 Aug 30.

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.3389/fimmu.2019.02064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730489PMC
August 2019

LION: a simple and rapid method to achieve CRISPR gene editing.

Cell Mol Life Sci 2019 Jul 18;76(13):2633-2645. Epub 2019 Mar 18.

Lars Bolund Institute of Regenerative Medicine, BGI-Qingdao, BGI-Shenzhen, Qingdao, 266555, China.

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http://dx.doi.org/10.1007/s00018-019-03064-xDOI Listing
July 2019

Structural modulation of gut microbiota reveals Coix seed contributes to weight loss in mice.

Appl Microbiol Biotechnol 2019 Jul 16;103(13):5311-5321. Epub 2019 Apr 16.

BGI Education Center, University of Chinese Academy of Sciences, Main building, Beishan Industrial Zone, Yantian District, Shenzhen, 518083, China.

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http://link.springer.com/10.1007/s00253-019-09786-z
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http://dx.doi.org/10.1007/s00253-019-09786-zDOI Listing
July 2019

Design and site-directed compartmentalization of gold nanoclusters within the intrasubunit interfaces of ferritin nanocage.

J Nanobiotechnology 2019 Jul 5;17(1):79. Epub 2019 Jul 5.

Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science & Nutritional Engineering, Beijing Key Laboratory of Functional Food from Plant Resources, China Agricultural University, Beijing, 100083, China.

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http://dx.doi.org/10.1186/s12951-019-0512-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612197PMC
July 2019

Rift Valley Fever Virus and Yellow Fever Virus in Urine: A Potential Source of Infection.

Virol Sin 2019 06 19;34(3):342-345. Epub 2019 Mar 19.

Beijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, 100015, China.

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http://dx.doi.org/10.1007/s12250-019-00096-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599495PMC
June 2019

Gene pathogenicity prediction of Mendelian diseases via the random forest algorithm.

Hum Genet 2019 Jun 8;138(6):673-679. Epub 2019 May 8.

BGI-Shenzhen, Shenzhen, 518083, China.

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http://dx.doi.org/10.1007/s00439-019-02021-9DOI Listing
June 2019

Immunosuppression Reduces Lung Injury Caused by Mycoplasma pneumoniae Infection.

Sci Rep 2019 May 9;9(1):7147. Epub 2019 May 9.

Department of Respiratory Medicine, Children's Hospital of Nanjing Medical University, Nanjing, 210000, China.

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http://dx.doi.org/10.1038/s41598-019-43451-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509254PMC
May 2019

The Effect of Hemicellulose and Lignin on Properties of Polysaccharides in and Their Antioxidant Evaluation.

Molecules 2019 May 13;24(9). Epub 2019 May 13.

College of Food Science and Nutritional Engineering, China Agricultural University, P. O. Box 40, No.17 Qinghuadonglu, Haidian, Beijing 100083, China.

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https://www.mdpi.com/1420-3049/24/9/1834
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http://dx.doi.org/10.3390/molecules24091834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539561PMC
May 2019

Developing a highly efficient and wildly adaptive CRISPR-SaCas9 toolset for plant genome editing.

Plant Biotechnol J 2019 04 12;17(4):706-708. Epub 2019 Feb 12.

Key Laboratory of Rice Genetic Breeding of Anhui Province, Rice Research Institute, Anhui Academy of Agricultural Sciences, Hefei, China.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/pbi.13047
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http://dx.doi.org/10.1111/pbi.13047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419570PMC
April 2019

Genomic analysis of liver cancer unveils novel driver genes and distinct prognostic features.

Theranostics 2018 12;8(6):1740-1751. Epub 2018 Feb 12.

Institute of Digestive Diseases and Department of Medicine & Therapeutics, State Key Laboratory of Digestive Diseases, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.7150/thno.22010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858179PMC
January 2019

A legacy of the "1% program" - The "Chinese Chapter" of the human genome reference sequence.

J Genet Genomics 2018 11 8;45(11):565-568. Epub 2018 Nov 8.

BGI-Shenzhen, Shenzhen 518083, China. Electronic address:

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http://dx.doi.org/10.1016/j.jgg.2018.10.003DOI Listing
November 2018

MiR-31 Mediates Inflammatory Signaling to Promote Re-Epithelialization during Skin Wound Healing.

J Invest Dermatol 2018 10 30;138(10):2253-2263. Epub 2018 Mar 30.

Beijing Advanced Innovation Center for Food Nutrition and Human Health and State Key Laboratories for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.03.1521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153075PMC
October 2018

Characterizing genomic differences of human cancer stratified by the TP53 mutation status.

Mol Genet Genomics 2018 Jun 12;293(3):737-746. Epub 2018 Jan 12.

BGI Genomics BGI-Shenzhen, Shenzhen, 518083, China.

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http://dx.doi.org/10.1007/s00438-018-1416-7DOI Listing
June 2018

Coexisting genomic aberrations associated with lymph node metastasis in breast cancer.

J Clin Invest 2018 06 23;128(6):2310-2324. Epub 2018 Apr 23.

Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1172/JCI97449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983317PMC
June 2018

De novo transcriptome sequencing and comprehensive analysis of the heat stress response genes in the basidiomycetes fungus Ganoderma lucidum.

Gene 2018 Jun 29;661:139-151. Epub 2018 Mar 29.

Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2018.03.093DOI Listing
June 2018

The landscape of somatic mutation in sporadic Chinese colorectal cancer.

Oncotarget 2018 Jun 8;9(44):27412-27422. Epub 2018 Jun 8.

Beijing Anzhen Hospital, Capital Medical University, The Key Laboratory of Remodeling-Related Cardiovascular Diseases, Ministry of Education, Beijing Collaborative Innovation Center for Cardiovascular Disorders, Beijing Institute of Heart, Lung and Blood Vessel Disease, Beijing, China.

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http://dx.doi.org/10.18632/oncotarget.25287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007951PMC
June 2018

Effect of heat stress on production and in-vitro antioxidant activity of polysaccharides in Ganoderma lucidum.

Bioprocess Biosyst Eng 2018 Jan 10;41(1):135-141. Epub 2017 Oct 10.

Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science and Nutritional Engineering, China Agricultural University, No. 17 Qinghua Donglu, Haidian District, Beijing, 100083, People's Republic of China.

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http://dx.doi.org/10.1007/s00449-017-1850-7DOI Listing
January 2018

Low-Boron Tolerance Strategies Involving Pectin-Mediated Cell Wall Mechanical Properties in Brassica napus.

Plant Cell Physiol 2017 Nov;58(11):1991-2005

National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, 430070, China.

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http://dx.doi.org/10.1093/pcp/pcx130DOI Listing
November 2017

MicroRNA-374c-5p regulates the invasion and migration of cervical cancer by acting on the Foxc1/snail pathway.

Biomed Pharmacother 2017 Oct 12;94:1038-1047. Epub 2017 Aug 12.

Department of Obstetrics and Gynecology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07533322173238
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http://dx.doi.org/10.1016/j.biopha.2017.07.150DOI Listing
October 2017

In silico modeling on ADME properties of natural products: Classification models for blood-brain barrier permeability, its application to traditional Chinese medicine and in vitro experimental validation.

J Mol Graph Model 2017 08 7;75:347-354. Epub 2017 Jun 7.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, No. 866 Yuhangtang Road, Hangzhou, 310058, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10933263173024
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http://dx.doi.org/10.1016/j.jmgm.2017.05.021DOI Listing
August 2017

Synergistic effects between [Si-hemicellulose matrix] ligands and Zn ions in inhibiting Cd ion uptake in rice (Oryza sativa) cells.

Planta 2017 May 30;245(5):965-976. Epub 2017 Jan 30.

College of Resources and Environment, Huazhong Agricultural University, Wuhan, 430070, China.

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http://dx.doi.org/10.1007/s00425-017-2655-2DOI Listing
May 2017

RNA-seq analysis of the hypothalamic transcriptome reveals the networks regulating physiopathological progress in the diabetic GK rat.

Sci Rep 2016 Sep 28;6:34138. Epub 2016 Sep 28.

School of Bioscience &Bioengineering, South China University of Technology, Guangzhou, 510006, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039700PMC
http://dx.doi.org/10.1038/srep34138DOI Listing
September 2016

Comparison of variations detection between whole-genome amplification methods used in single-cell resequencing.

Gigascience 2015 6;4:37. Epub 2015 Aug 6.

BGI-Shenzhen, Shenzhen, 518083 China ; Princess Al Jawhara Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, 21589 Saudi Arabia ; Department of Biology and the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, 1599 Denmark.

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http://dx.doi.org/10.1186/s13742-015-0068-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527218PMC
July 2016

Risk Factors and Early Predictors for Heterotopic Pregnancy after In Vitro Fertilization.

PLoS One 2015 28;10(10):e0139146. Epub 2015 Oct 28.

Center for Reproductive Medicine, Provincial Hospital Affiliated to Shandong University, Jinan 250001, China; National Research Center for Assisted Reproductive Technology and Reproductive Genetic, Jinan, China; The Key laboratory for Reproductive Endocrinology of Ministry of Education, Jinan, China; Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan 250021, China; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139146PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624796PMC
June 2016

A novel splice donor site mutation in EPHA2 caused congenital cataract in a Chinese family.

Indian J Ophthalmol 2016 May;64(5):364-8

BGI-Shenzhen, Shenzhen 518083; The Guangdong Enterprise Key Laboratory of Human Disease Genomics, Shenzhen 518083; Shenzhen Key Laboratory of Genomics, Shenzhen 518083, China.

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http://dx.doi.org/10.4103/0301-4738.185597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966373PMC
May 2016

Synthesis of photoresponsive cholesterol-based azobenzene organogels: dependence on different spacer lengths.

Beilstein J Org Chem 2015 29;11:1089-95. Epub 2015 Jun 29.

Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province of China, China West Normal University, Nanchong 637009, China.

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http://dx.doi.org/10.3762/bjoc.11.122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505088PMC
July 2015

Family-based analysis of eight susceptibility loci in polycystic ovary syndrome.

Sci Rep 2015 Jul 29;5:12619. Epub 2015 Jul 29.

1] Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China [2] Center for Reproductive Medicine, Provincial Hospital Affiliated to Shandong University, Jinan, China; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, China; The Key laboratory for Reproductive Endocrinology of Ministry of Education, China; Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan, China.

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http://dx.doi.org/10.1038/srep12619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518258PMC
July 2015

De novo assembly of a haplotype-resolved human genome.

Nat Biotechnol 2015 Jun 25;33(6):617-22. Epub 2015 May 25.

1] BGI-Shenzhen, Shenzhen, China. [2] Department of Biology, University of Copenhagen, Copenhagen, Denmark. [3] Princess Al Jawhara Albrahim Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia. [4] Macau University of Science and Technology, Taipa, Macau, China. [5] Department of Medicine and State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1038/nbt.3200DOI Listing
June 2015

Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22.

PLoS Genet 2015 May 28;11(5):e1005253. Epub 2015 May 28.

State Key Laboratories for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.1371/journal.pgen.1005253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447420PMC
May 2015

Embryo genome profiling by single-cell sequencing for preimplantation genetic diagnosis in a β-thalassemia family.

Clin Chem 2015 Apr 26;61(4):617-26. Epub 2015 Feb 26.

BGI-Shenzhen, Shenzhen, China; Department of Biology, University of Copenhagen, Copenhagen, Denmark; King Abdulaziz University, Jeddah, Saudi Arabia; The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen.

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http://www.clinchem.org/cgi/doi/10.1373/clinchem.2014.228569
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http://dx.doi.org/10.1373/clinchem.2014.228569DOI Listing
April 2015

Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing.

Gigascience 2014 4;3(1):30. Epub 2014 Dec 4.

Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, China ; National Engineering and Research Center of Human Stem Cell, Changsha, China ; Reproductive & Genetic Hospital of CITIC Xiangya, Changsha, China ; Key Laboratory of Stem Cell and Reproductive Engineering, Ministry of Health, Changsha, China.

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http://dx.doi.org/10.1186/2047-217X-3-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326468PMC
February 2015

Non-invasive fetal sex determination by maternal plasma sequencing and application in X-linked disorder counseling.

J Matern Fetal Neonatal Med 2014 Dec 20;27(18):1829-33. Epub 2014 Feb 20.

School of Bioscience and Bioengineering, South China University of Technology , Guangzhou , China .

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http://dx.doi.org/10.3109/14767058.2014.885942DOI Listing
December 2014

Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA.

Nature 2014 Aug 2;512(7513):194-7. Epub 2014 Jul 2.

1] BGI-Shenzhen, Shenzhen 518083, China [2] Department of Integrative Biology, University of California, Berkeley, California 94720 USA [3] Department of Statistics, University of California, Berkeley, California 94720, USA [4] Department of Biology, University of Copenhagen, 2200 Copenhagen, Denmark.

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http://www.nature.com/articles/nature13408
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http://dx.doi.org/10.1038/nature13408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134395PMC
August 2014

Multilayered molecular profiling supported the monoclonal origin of metastatic renal cell carcinoma.

Int J Cancer 2014 Jul 21;135(1):78-87. Epub 2013 Dec 21.

Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen, China; National-Regional Key Technology Engineering Laboratory for Clinical Application of Cancer Genomics, Shenzhen Key Laboratory of Genitourinary Tumor, Shenzhen, China.

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http://dx.doi.org/10.1002/ijc.28654DOI Listing
July 2014

Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing.

Cell Res 2014 Jun 4;24(6):701-12. Epub 2014 Apr 4.

1] BGI-Shenzhen, Shenzhen, Guangdong 518083, China [2] Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark [3] Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia [4] Macau University of Science and Technology, Avenida Wai long, Taipa, Macau 999078, China.

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http://www.nature.com/articles/cr201443
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http://dx.doi.org/10.1038/cr.2014.43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042168PMC
June 2014

Identification of somatic alterations in stage I lung adenocarcinomas by next-generation sequencing.

Genes Chromosomes Cancer 2014 Apr 22;53(4):289-98. Epub 2014 Jan 22.

Department of Thoracic Surgery, Cancer Institute and Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

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http://dx.doi.org/10.1002/gcc.22138DOI Listing
April 2014

HIVID: an efficient method to detect HBV integration using low coverage sequencing.

Genomics 2013 Oct 15;102(4):338-44. Epub 2013 Jul 15.

BGI-Shenzhen, Shenzhen, 518083, China; School of Bioscience and Bioengineering, South China University of Technology, China.

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http://dx.doi.org/10.1016/j.ygeno.2013.07.002DOI Listing
October 2013

Replication study of RAD54B and GREB1 polymorphisms and risk of PCOS in Han Chinese.

Reprod Biomed Online 2013 Sep 22;27(3):316-21. Epub 2013 May 22.

Center for Reproductive Medicine, Provincial Hospital Affiliated to Shandong University, 324 Jingwu Road, Jinan 250021, China.

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http://dx.doi.org/10.1016/j.rbmo.2013.05.007DOI Listing
September 2013

Integrated detection of both 5-mC and 5-hmC by high-throughput tag sequencing technology highlights methylation reprogramming of bivalent genes during cellular differentiation.

Epigenetics 2013 Apr 15;8(4):421-30. Epub 2013 Mar 15.

Science & Technology Department; BGI-Shenzhen; Shenzhen, China; Department of Biology; University of Copenhagen; Copenhagen, Denmark; King Abdulaziz University; Jeddah, Saudi Arabia; The Novo Nordisk Foundation Center for Basic Metabolic Research; University of Copenhagen; Copenhagen, Denmark.

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http://www.tandfonline.com/doi/abs/10.4161/epi.24280
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http://dx.doi.org/10.4161/epi.24280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674051PMC
April 2013

Rapid detection of aneuploidies on a benchtop sequencing platform.

Prenat Diagn 2013 Mar 28;33(3):232-7. Epub 2013 Jan 28.

BGI-Shenzhen, Shenzhen, China.

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http://dx.doi.org/10.1002/pd.4049DOI Listing
March 2013

Deep sequencing reveals small RNA characterization of invasive micropapillary carcinomas of the breast.

Breast Cancer Res Treat 2012 Nov 14;136(1):77-87. Epub 2012 Sep 14.

Department of Breast Cancer Pathology and Research Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin, People's Republic of China.

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http://dx.doi.org/10.1007/s10549-012-2166-6DOI Listing
November 2012