Publications by authors named "Xinru Han"

6 Publications

  • Page 1 of 1

Impacts of China's bioethanol policy on the global maize market: a partial equilibrium analysis to 2030.

Food Secur 2021 Sep 17:1-17. Epub 2021 Sep 17.

Institute of Agricultural Economics and Development, Chinese Academy of Agricultural Sciences, Beijing, 100081 China.

Maize is a major component of China's cereal production. It is also one of the main feedstocks for China's bioethanol production. To ensure food security, there is flexibility in China's ethanol policy. In this paper, we build a multicountry and multisector partial equilibrium model to simulate the possible impacts of biofuel policy on maize markets and food security. Considering normal macroeconomic conditions, China's bioethanol promotion policy would result in a net increase in maize imports to 26 mmt in 2030. Meanwhile, China's maize self-sufficiency ratio would decrease to 92% in 2030 as a result of the country's bioethanol promotion policy. In addition, simulation results indicate that China's bioethanol promotion policy could increase the world maize price index by 5% and the world bioethanol price index by 4% in 2030. Based on this modeling study, the Chinese government may take measures in advance to prepare for large-scale maize imports, adjust its strategy in order to make better use of the international market, and strengthen international trade and stock cooperation with maize import regions and countries.

Supplementary Information: The online version contains supplementary material available at 10.1007/s12571-021-01212-5.
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http://dx.doi.org/10.1007/s12571-021-01212-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446480PMC
September 2021

Antitumor potential of Hedyotis diffusa Willd: A systematic review of bioactive constituents and underlying molecular mechanisms.

Biomed Pharmacother 2020 Oct 12;130:110735. Epub 2020 Sep 12.

Department of Pharmacy, Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250013, China. Electronic address:

Cancer is a major cause of death in the world. Chemotherapy can extend the life of cancer patients to some extent, but the quality of life is reduced. Therefore, the quest for more efficient and less toxic medication strategies is still at the forefront of current research. Hedyotis diffusa Willd (HDW), a Chinese herb medicine, has received great attention in the past two decades and has been well documented in clinics for antitumor activity in a variety of human cancers. This review discussed a total of 58 different kinds of active antitumor components isolated from HDW, including iridoids, flavonoids, flavonol glycosides, anthraquinones, phenolic acids, and their derivatives, sterols, and volatile oils. Their antitumor activities include inhibition of tumor cell proliferation, induction of tumor cell apoptosis and tumor angiogenesis, regulation of the host immune response, anti-inflammatory and antioxidant, and protective autophagy. Besides, we provide up-to-date and systematic evidence for HDW antitumor activities and the possible underlying molecular mechanisms and reference for further development of novel drugs and dosage formulation in control of human cancers.
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http://dx.doi.org/10.1016/j.biopha.2020.110735DOI Listing
October 2020

Internet Access and Nutritional Intake: Evidence from Rural China.

Nutrients 2021 Jun 11;13(6). Epub 2021 Jun 11.

Institute of Agricultural Economics and Development, Chinese Academy of Agricultural Sciences, Beijing 100081, China.

Over the past 4 decades, China has experienced a nutritional transition and has developed the largest population of internet users. In this study, we evaluated the impacts of internet access on the nutritional intake in Chinese rural residents. An IV-Probit-based propensity score matching method was used to determine the impact of internet access on nutritional intake. The data were collected from 10,042 rural households in six Chinese provinces. The results reveal that rural residents with internet access have significantly higher energy, protein, and fat intake than those without. Chinese rural residents with internet access consumed 1.35% (28.62 kcal), 5.02% (2.61 g), and 4.33% (3.30 g) more energy, protein, and fat, respectively. There was heterogeneity in regard to the intake of energy, protein, and fat among those in different income groups. Moreover, non-staple food consumption is the main channel through which internet access affects nutritional intake. The results demonstrate that the local population uses the internet to improve their nutritional status. Further studies are required to investigate the impact of internet use on food consumed away from home and micronutrient intake.
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http://dx.doi.org/10.3390/nu13062015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230947PMC
June 2021

Activation of adenosine A2a receptor accelerates and A2a receptor antagonist reduces intermittent hypoxia induced PC12 cell injury via PKC-KATP pathway.

Brain Res Bull 2019 08 23;150:118-126. Epub 2019 May 23.

Department of Pediatrics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Western Road, Wenzhou, Zhejiang, 325027, PR China; The Second School Of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang, PR China. Electronic address:

Obstructive sleep apnea hypopnea syndrome (OSAHS) is associated with multiple system diseases. Neurocognitive dysfunction resulting from central nervous system complications has been reported, especially in children with OSAHS. Chronic intermittent hypoxia is accepted to be the major pathophysiological mechanism of OSAHS. Adenosine plays an important role in cellular function via interactions with its receptors. A2a receptor has been recognized as a factor involved in neuroprotection. However, the role of adenosine A2a receptor in intermittent hypoxia induced cellular injury is not completely understood. In this study, we aim to investigate the underlying mechanisms of A2a receptor mediated cellular damage caused by intermittent hypoxia in PC12 cells. We found that activated A2a receptor by CGS21680 decreased cellular viability, increased PKC as well as ATP-sensitive potassium channel (KATP) subunits expression Kir6.2 and SUR1. Inhibition of A2a receptor by SCH58261 increased cellular viability, suppressed PKC and SUR1 expression level, ultimately showing a protective role in PC12 cells. Moreover, we observed that CHE, which is an antagonist of PKC, downregulated Kir6.2 and SUR1 expression and increased cellular viability. Additionally, we found that A2a receptor activation induced cell injury was associated with increased Cleaved-Caspase 3 expression, which can be decreased by inhibition of A2a receptor or PKC. In conclusion, our findings indicate that A2a receptor induced KATP expression by PKC activation and plays a role in accelerating PC12 cells injury induced by intermittent hypoxia exposure via A2a-PKC-KATP signal pathway mediated apoptosis.
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http://dx.doi.org/10.1016/j.brainresbull.2019.05.015DOI Listing
August 2019

Direct and indirect effects of wastewater use and herd environment on the occurrence of animal diseases and animal health in Pakistan.

Environ Sci Pollut Res Int 2017 Mar 14;24(7):6819-6832. Epub 2017 Jan 14.

Institute of Agricultural Economics and Development, Chinese Academy of Agricultural Science, Beijing, 100081, China.

The use of wastewater for rearing domestic animals is a common phenomenon in most of the developing countries like Pakistan that face a serious shortage of freshwater resources. However, most of the literature has only focused on the indirect effects of wastewater use on animal health or productivity, and literature on the direct effects of wastewater use is rare. Therefore, this study aims to investigate the direct and indirect effects of wastewater usage on the prevalence of animal diseases and animal health in Pakistan. The study is based on a household-level survey of 360 domestic water buffalo herds collected from 12 districts of Punjab Province, Pakistan. We tested the prevalence of the animal's diseases, animal's health, and wastewater-use preference with various econometric tools, such as the Poisson, negative binomial, and logistic regressions. The findings of the study show that the majority of the farmers use wastewater for buffalo bathing due to the shortage of freshwater resources. Results explore the prevalence of diseases such as clinical mastitis, tick infestation, and foot and mouth disease at the farm level significantly associated with buffalo bathing in the wastewater. Moreover, bathing in wastewater pre- and post-milking also plays a role in the occurrence of diseases. Particularly, if the buffalo's access to wastewater for bathing is within 60 min after milking, the probability of the animals being exposed to mastitis is higher. Furthermore, on investigation, a number of factors are found, such as the distance to the water source, power shortage, groundwater availability, and the education of farmers that influence farmers' behavior of letting their animals take a bath in wastewater. Moreover, the use of different preventive measures improves the animal's health.
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http://dx.doi.org/10.1007/s11356-017-8423-9DOI Listing
March 2017

An assessment of climate change impacts on maize yields in Hebei Province of China.

Sci Total Environ 2017 Mar 4;581-582:507-517. Epub 2017 Jan 4.

National Institute for Agro-Environmental Sciences, 3-1-3 Kannondai, Tsukuba 305-8604, Japan. Electronic address:

The climate change impacts on maize yields are quantified in this paper using statistical models with panel data from 3731 farmers' observations across nine sample villages in Hebei Province of China. The marginal impacts of climate change and the simulated impacts on maize yields based on scenarios of Representative Concentration Pathways 2.6, 4.5, 6.0, and 8.5 from the global climate models of Model for Interdisciplinary Research on Climate version 5 (MIROC5) and Meteorological Research Institute Coupled General Circulation Model version 3 (MRI-CGCM3) were then calculated, analyzed, and explained. The results indicate that, first, the most important finding was that climate change impacts on maize yields were significant and a 1°C warming or a 1mm decrease in precipitation resulted in a 150.255kg or a 1.941kg loss in maize yields per hectare, respectively. Second, villages with latitudes of less than 39.832 and longitudes of more than 114.839 in Hebei province suffered losses due to warm weather. Third, the simulated impacts for the full sample are all negative based on scenarios from MIROC5, and their magnitudes are more than those of MRI-CGCM3 are. Based on scenarios in the 2050s, the biggest loss for maize yields per hectare for the full sample accounts for about one-tenth of the mean maize yield from 2004 to 2010, and all of the villages are impacted. Hence, it is important to help farms adopt an adaptation strategy to tackle the risk of loss for maize yields from climate change, and it is necessary to develop agricultural synthesis services as a public adaptation policy at the village level to interact with the adaptation strategy at the farm level.
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http://dx.doi.org/10.1016/j.scitotenv.2016.12.158DOI Listing
March 2017
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