Publications by authors named "Xindi He"

3 Publications

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Clinical characteristics of sinonasal inverted papilloma associated with recurrence and malignant transformation.

Authors:
Xindi He Ying Wang

Auris Nasus Larynx 2021 May 5. Epub 2021 May 5.

Department of Rhinology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. Electronic address:

Objective: Sinonasal inverted papilloma is a benign tumor but has a potential for recurrence and malignant transformation. The aim of this article is to analyze the clinical characteristics of sinonasal inverted papilloma associated with recurrence and malignant transformation.

Material And Methods: A retrospective study was performed in all patients with sinonasal inverted papilloma diagnosed between in our hospital during May 2013 and May 2018.

Results: A total of 151 patients were enrolled in this study. The average age of these patients was 52.24 years, with a male-to-female ratio of 2.775:1, and the most frequent clinical symptom was nasal obstruction. The recurrence rate was 39.07% (59/151), the mean time of recurrence was 35.8 months and most recurrences occur within the first three years after surgery. There was no significant difference in recurrence rate between all four stages and between after endoscopic surgery and a combined endoscopic and external approach. The malignant transformation rate was 5.96% (9/151) and the mean time of malignant transformation was 9.06 months.

Conclusions: Because of its high recurrence rate and the potential of malignant transformation, so it is important to determine the primary site of the tumor and to make a complete removal and a follow-up of at least five years after surgery is recommended.
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http://dx.doi.org/10.1016/j.anl.2021.04.008DOI Listing
May 2021

Neurilemmoma of the Nasal Cavity and Paranasal Sinuses.

Authors:
Xindi He Ying Wang

Ear Nose Throat J 2021 May 5:1455613211007947. Epub 2021 May 5.

Department of Rhinology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Objectives: Neurilemmoma in the nasal cavity and paranasal sinuses is very rare. The study aimed to improve the understanding of neurilemmoma in the nasal cavity and paranasal sinuses.

Materials And Methods: The clinical data of 10 patients with neurilemmoma in the nasal cavity and paranasal sinuses treated from January 2014 to June 2019 in our hospital were retrospectively studied.

Results: There were 6 females and 4 males patients in our study. The mean age was 49.5 years (range 37-77 years), and the most common clinical symptom was unilateral nasal obstruction. The site of tumor included the nasal cavity, maxillary sinus, ethmoid sinus, and sphenoid sinus. There were 2 cases with malignant neurilemmoma. Nine patients underwent functional endoscopic sinus surgery (FESS); however, 1 patient underwent FESS combined with the lateral rhinotomy for complete resection of the tumor. Two patients with malignant neurilemmoma received postoperative radiotherapy. The mean follow-up was 3.82 years (range 2-7 years). There were no incidences of tumor recurrence during the study period.

Conclusions: Neurilemmoma in the nasal cavity and paranasal sinuses is a mainly benign tumor. Complete surgical excision by FESS is the only treatment option for neurilemmoma in the nasal cavity and paranasal sinuses; while malignant neurilemmoma needs postoperative radiotherapy.
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http://dx.doi.org/10.1177/01455613211007947DOI Listing
May 2021

[Clinical analysis of 31 cases of esthesioneuroblastoma].

Authors:
Xindi He Ying Wang

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Apr;35(4):338-340

Department of Rhinology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou,450052,China.

To investigate the clinical characteristics and prognostic factors of esthesioneuroblastoma. The clinical data of 31 patients with esthesioneuroblastoma were retrospectively studied. The average time from first onset to diagnosis in 31 patients was 7.84 months, among which 3 patients(9.68%) had cervical lymph node metastasis at the first visit. By the end of follow-up, there were 25 coexisting cases and 6 deaths. The mean recurrence time of 6 patients was 10.6 months. There were 6 patients with distant metastasis, including 4 patients with cervical lymph node metastasis, 1 patient with liver metastasis and 1 patient with bone metastasis. Modified Kadish stage, different treatment methods, recurrence, first diagnosis of cervical lymph node metastasis, and distant metastasis were all factors affecting the prognosis of the patients. The incidence of esthesioneuroblastoma is low and the comprehensive treatment of surgery combined with radiotherapy is the optimal treatment plan. Patients with low Kadish staging, surgical combined with radiotherapy, no recurrence, no initial cervical lymph node metastasis, and no distant metastasis have a better prognosis.
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http://dx.doi.org/10.13201/j.issn.2096-7993.2021.04.012DOI Listing
April 2021