Xin-Sheng Yao

Xin-Sheng Yao

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Xin-Sheng Yao

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Two new alcohol glycosides from the roots of C. A. Meyer.

J Asian Nat Prod Res 2019 Oct 4:1-7. Epub 2019 Oct 4.

School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University , Shenyang 110016 , China.

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http://dx.doi.org/10.1080/10286020.2019.1666824DOI Listing
October 2019

A new cinnamamide derivative and two new β-carboline alkaloids from the stems of Picrasma quassioides.

Fitoterapia 2019 Oct 16:104375. Epub 2019 Oct 16.

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2019.104375DOI Listing
October 2019

New phthalide derivatives from the Biscogniauxia sp. and their activities.

Fitoterapia 2019 Sep 28;137:104184. Epub 2019 May 28.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2019.104184DOI Listing
September 2019

Nardosinanone N suppresses LPS-induced macrophage activation by modulating the Nrf2 pathway and mPGES-1.

Biochem Pharmacol 2019 Sep 16:113639. Epub 2019 Sep 16.

Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wailong, Taipa, Macau, PR China; State Key Laboratory of Quality Research in Chinese Medicine (Macau University of Science and Technology), Avenida Wailong, Taipa, Macao, PR China; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Macau University of Science and Technology, Avenida Wailong, Taipa, Macao, PR China; Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Zhuhai City, Guangdong Province 519000, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2019.113639DOI Listing
September 2019

Effect and mechanism of psoralidin on promoting osteogenesis and inhibiting adipogenesis.

Phytomedicine 2019 Aug 4;61:152860. Epub 2019 Feb 4.

Translational Medicine R&D Center, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518057, China; Musculoskeletal Research Laboratory of Department of Orthopaedics & Traumatology and Innovative Orthopaedic Biomaterial and Drug Translational Research Laboratory of Li Ka Shing Institute of Health, The Chinese University of Hong Kong, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2019.152860DOI Listing
August 2019

Phenylpropanoid glycosides from the fruit of Lycium barbarum L. and their bioactivity.

Phytochemistry 2019 Aug 13;164:60-66. Epub 2019 May 13.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy / Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00319422193016
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http://dx.doi.org/10.1016/j.phytochem.2019.04.017DOI Listing
August 2019

Monoterpene glycosides with anti-inflammatory activity from Paeoniae Radix.

Fitoterapia 2019 Aug 6;138:104290. Epub 2019 Aug 6.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drug Research, Jinan University, Guangzhou 510632, China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2019.104290DOI Listing
August 2019

Anti-inflammatory glycosides from the roots of C. A. Meyer.

Nat Prod Res 2019 Aug 27:1-7. Epub 2019 Aug 27.

School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University , Shenyang , China.

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http://dx.doi.org/10.1080/14786419.2019.1655020DOI Listing
August 2019

Simultaneous determination of multiple components in rat plasma and pharmacokinetic studies at a pharmacodynamic dose of Xian-Ling-Gu-Bao capsule by UPLC-MS/MS.

J Pharm Biomed Anal 2019 Aug 26;177:112836. Epub 2019 Aug 26.

College of Pharmacy and International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education, Jinan University, Guangzhou 510632, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2019.112836DOI Listing
August 2019

C-Methylated flavanones from the rhizomes of Matteuccia intermedia and their α-glucosidase inhibitory activity.

Fitoterapia 2019 Jul 22;136:104147. Epub 2019 Apr 22.

School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China; Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2019.04.002DOI Listing
July 2019

New phenylpropanoid allopyranosides from the rhizomes of Cimicifuga dahurica.

Bioorg Med Chem Lett 2019 Jul 8;29(14):1774-1778. Epub 2019 May 8.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drug Research, Jinan University, Guangzhou 510632, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X193029
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http://dx.doi.org/10.1016/j.bmcl.2019.05.011DOI Listing
July 2019

NMR Applications for Botanical Mixtures: The Use of HSQC Data to Determine Lignan Content in .

J Nat Prod 2019 Jul 8;82(7):1733-1740. Epub 2019 Jul 8.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy , Jinan University , Guangzhou 510632 , People's Republic of China.

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http://dx.doi.org/10.1021/acs.jnatprod.8b00891DOI Listing
July 2019

Cladosporine A, a new indole diterpenoid alkaloid with antimicrobial activities from sp.

Nat Prod Res 2019 Jul 15:1-7. Epub 2019 Jul 15.

a Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy , Jinan University , Guangzhou , People's Republic of China.

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http://dx.doi.org/10.1080/14786419.2019.1641807DOI Listing
July 2019

Spororrminone A and 2--spororrminone A, two new chromones from an endolichenic fungus .

Nat Prod Res 2019 Jun 26:1-8. Epub 2019 Jun 26.

a Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy , Jinan University , Guangzhou , People's Republic of China.

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http://dx.doi.org/10.1080/14786419.2019.1610758DOI Listing
June 2019

Triangeliphthalides A-D: bioactive phthalide trimers with new skeletons from Angelica sinensis and their production mechanism.

Chem Commun (Camb) 2019 May;55(44):6221-6224

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China.

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http://dx.doi.org/10.1039/c9cc02681aDOI Listing
May 2019

Phenolic acids and their glycosides from the rhizomes of Cimicifuga dahurica.

Fitoterapia 2019 Apr 23;134:485-492. Epub 2019 Mar 23.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drug Research, Jinan University, Guangzhou 510632, China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2019.03.023DOI Listing
April 2019

Discovery of the mechanisms and major bioactive compounds responsible for the protective effects of Gualou Xiebai Decoction on coronary heart disease by network pharmacology analysis.

Phytomedicine 2019 Mar 8;56:261-268. Epub 2018 Nov 8.

Faculty of Chinese Medicine, Macau University of Science and Technology and State Key Laboratory of Quality Research in Chinese Medicine (Macau University of Science and Technology), Taipa, Macau, PR China; Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09447113183056
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http://dx.doi.org/10.1016/j.phymed.2018.11.010DOI Listing
March 2019

Design and synthesis of biotinylated cardiac glycosides for probing Nur77 protein inducting pathway.

Bioorg Med Chem Lett 2019 Mar 16;29(5):707-712. Epub 2019 Jan 16.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.01.015DOI Listing
March 2019

Discovery of cardio-protective constituents of Gualou Xiebai Decoction, a classical traditional Chinese medicinal formula.

Phytomedicine 2019 Feb 18;54:318-327. Epub 2018 Apr 18.

Faculty of Chinese Medicine, Macau University of Science and Technology and State Key Laboratory of Quality Research in Chinese Medicine (Macau University of Science and Technology), Taipa, Macau, PR China; College of Pharmacy, Jinan University, Guangzhou 510632, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2018.04.047DOI Listing
February 2019

Effectiveness and safety of chemotherapy with cytokine-induced killer cells in non-small cell lung cancer: A systematic review and meta-analysis of 32 randomized controlled trials.

Cytotherapy 2019 Feb 14;21(2):125-147. Epub 2018 Dec 14.

Evidence-Based Medicine Center, MOE Virtual Research Center of Evidence-based Medicine at Zunyi Medical College, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China; Department of Respiratory Medicine (Center for Evidence-Based and Translational Medicine of major infectious diseases), Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.

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http://dx.doi.org/10.1016/j.jcyt.2018.10.011DOI Listing
February 2019

Biosynthesis of an anti-tuberculosis sesterterpenoid asperterpenoid A.

Org Biomol Chem 2019 01;17(2):248-251

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China.

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http://xlink.rsc.org/?DOI=C8OB02832J
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http://dx.doi.org/10.1039/c8ob02832jDOI Listing
January 2019

Strengthen the research on the medicinal and edible substances to advance the development of the comprehensive healthcare industry of TCMs.

Chin J Nat Med 2019 Jan;17(1):1-2

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China. Electronic address:

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http://dx.doi.org/10.1016/S1875-5364(19)30002-0DOI Listing
January 2019

Two new ursane-type nortriterpenes from Lonicera macranthoides and their iNOS-inhibitory activities.

Chin J Nat Med 2019 Jan;17(1):27-32

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, China; College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address:

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http://dx.doi.org/10.1016/S1875-5364(19)30006-8DOI Listing
January 2019

Nardochinoids A-C, Three Dimeric Sesquiterpenoids with Specific Fused-Ring Skeletons from Nardostachys chinensis.

Org Lett 2018 09 29;20(18):5813-5816. Epub 2018 Aug 29.

College of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang , 110016 , China.

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http://dx.doi.org/10.1021/acs.orglett.8b02511DOI Listing
September 2018

Antiviral phenolics from Antenoron filiforme var. neofiliforme.

J Asian Nat Prod Res 2018 Aug 21;20(8):763-769. Epub 2017 Nov 21.

a School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education , Shenyang Pharmaceutical University , Shenyang 110016 , China.

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http://dx.doi.org/10.1080/10286020.2017.1351437DOI Listing
August 2018

The Protective Effects of Gardenia jasminoides (Fructus Gardenia) on Amyloid-β-Induced Mouse Cognitive Impairment and Neurotoxicity.

Am J Chin Med 2018 12;46(2):389-405. Epub 2018 Feb 12.

* Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Xian Nong Tan Street, Beijing 100050, P. R. China.

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http://dx.doi.org/10.1142/S0192415X18500192DOI Listing
August 2018

Clinical efficacy and safety of CIK plus radiotherapy for lung cancer: A meta-analysis of 16 randomized controlled trials.

Int Immunopharmacol 2018 Aug 23;61:363-375. Epub 2018 Jun 23.

Outpatient Department of Psychological Counseling Clinic (Center for Evidence-Based and Translational Medicine of major infectious diseases), Affiliated Hospital of Zunyi Medical College, Zunyi 563000, Guizhou, China.

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http://dx.doi.org/10.1016/j.intimp.2018.06.012DOI Listing
August 2018

A Metabolomics Study on the Bone Protective Effects of a Lignan-Rich Fraction From Sambucus Williamsii Ramulus in Aged Rats.

Front Pharmacol 2018 21;9:932. Epub 2018 Aug 21.

State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, China.

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http://dx.doi.org/10.3389/fphar.2018.00932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110923PMC
August 2018

New alkylresorcinols from the fruits of Embelia ribes.

Fitoterapia 2018 Jul 1;128:66-72. Epub 2018 May 1.

School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China; Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2018.04.022DOI Listing
July 2018

Systematic screening and characterization of Qi-Li-Qiang-Xin capsule-related xenobiotics in rats by ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2018 Jul 12;1090:56-64. Epub 2018 May 12.

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China; College of Pharmacy and Guangdong Provincial Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15700232183019
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http://dx.doi.org/10.1016/j.jchromb.2018.05.014DOI Listing
July 2018

A combination of representative compounds, metabolism platform and diagnostic extraction strategy for characterization of metabolites of Shuang-Huang-Lian oral liquid in vivo by ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry.

J Pharm Biomed Anal 2018 Jun 4;155:216-234. Epub 2018 Apr 4.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine & New Drug Research, Jinan University, Guangzhou 510632, China; College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2018.03.066DOI Listing
June 2018

New secoiridoids from the fruits of Ligustrum lucidum.

J Asian Nat Prod Res 2018 May 28;20(5):431-438. Epub 2018 Mar 28.

a Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine & New Drug Research, College of Pharmacy , Jinan University , Guangzhou 510632 , China.

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http://dx.doi.org/10.1080/10286020.2018.1454438DOI Listing
May 2018

Biosynthetic pathway for furanosteroid demethoxyviridin and identification of an unusual pregnane side-chain cleavage.

Nat Commun 2018 05 9;9(1):1838. Epub 2018 May 9.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, 510632, Guangzhou, People's Republic of China.

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http://dx.doi.org/10.1038/s41467-018-04298-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943271PMC
May 2018

Gualou Xiebai Decoction, a Traditional Chinese Medicine, Prevents Cardiac Reperfusion Injury of Hyperlipidemia Rat via Energy Modulation.

Front Physiol 2018 4;9:296. Epub 2018 Apr 4.

State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.

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http://dx.doi.org/10.3389/fphys.2018.00296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895855PMC
April 2018

New lignans attenuating cognitive deterioration of Aβ transgenic flies discovered in Acorus tatarinowii.

Bioorg Med Chem Lett 2018 02 10;28(4):814-819. Epub 2017 Aug 10.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.08.015DOI Listing
February 2018

Synthesis of C-Neoglycosides of digoxigenin and their anticancer activities.

Eur J Med Chem 2018 Feb 2;145:252-262. Epub 2018 Jan 2.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.12.086DOI Listing
February 2018

Triligustilides A and B: Two Pairs of Phthalide Trimers from Angelica sinensis with a Complex Polycyclic Skeleton and Their Activities.

Org Lett 2018 02 23;20(3):884-887. Epub 2018 Jan 23.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, and ‡College of Traditional Chinese Medicine, Jinan University , Guangzhou 510632, People's Republic of China.

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http://dx.doi.org/10.1021/acs.orglett.8b00017DOI Listing
February 2018

Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism.

Nutrients 2018 Feb 22;10(2). Epub 2018 Feb 22.

Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

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http://www.mdpi.com/2072-6643/10/2/247
Publisher Site
http://dx.doi.org/10.3390/nu10020247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852823PMC
February 2018

Phenylisotertronic acids from the TCM endophytic fungus Phyllosticta sp.

Fitoterapia 2018 Jan 23;124:86-91. Epub 2017 Oct 23.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, China; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2017.10.016DOI Listing
January 2018

C-glycosides from the stems of Calophyllum membranaceum.

J Asian Nat Prod Res 2018 Jan 6;20(1):49-54. Epub 2017 Dec 6.

a Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang 110016 , China.

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http://dx.doi.org/10.1080/10286020.2017.1409734DOI Listing
January 2018

Matteucens I-J, phenolics from the rhizomes of Matteuccia orientalis.

J Asian Nat Prod Res 2018 Jan 13;20(1):62-66. Epub 2017 Dec 13.

a School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education , Shenyang Pharmaceutical University , Shenyang 110016 , China.

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http://dx.doi.org/10.1080/10286020.2017.1409735DOI Listing
January 2018

Dimeric Cadinane Sesquiterpenoid Derivatives from Artemisia annua.

Org Lett 2018 01 4;20(2):453-456. Epub 2018 Jan 4.

State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology , AvenidaWailong, Taipa, Macau.

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http://pubs.acs.org/doi/10.1021/acs.orglett.7b03796
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http://dx.doi.org/10.1021/acs.orglett.7b03796DOI Listing
January 2018

Houttuynoid M, an Anti-HSV Active Houttuynoid from Houttuynia cordata Featuring a Bis-houttuynin Chain Tethered to a Flavonoid Core.

J Nat Prod 2017 11 3;80(11):3010-3013. Epub 2017 Nov 3.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University , Guangzhou 510632, People's Republic of China.

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http://dx.doi.org/10.1021/acs.jnatprod.7b00620DOI Listing
November 2017

Bioactive Asarone-Derived Phenylpropanoids from the Rhizome of Acorus tatarinowii Schott.

J Nat Prod 2017 11 8;80(11):2923-2929. Epub 2017 Nov 8.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, and ‡Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University , Guangzhou 510632, People's Republic of China.

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http://pubs.acs.org/doi/10.1021/acs.jnatprod.7b00457
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http://dx.doi.org/10.1021/acs.jnatprod.7b00457DOI Listing
November 2017

Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis.

Nat Commun 2017 11 21;8(1):1644. Epub 2017 Nov 21.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, 510632, People's Republic of China.

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http://dx.doi.org/10.1038/s41467-017-01813-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696383PMC
November 2017

Chiral resolution, absolute configuration, and bioactivity of a new racemic asarone derivative from the rhizome of Acorus tatarinowii.

Fitoterapia 2017 Oct 12;122:7-10. Epub 2017 Aug 12.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2017.08.004DOI Listing
October 2017

Phyllomeroterpenoids A-C, Multi-biosynthetic Pathway Derived Meroterpenoids from the TCM Endophytic Fungus Phyllosticta sp. and their Antimicrobial Activities.

Sci Rep 2017 10 10;7(1):12925. Epub 2017 Oct 10.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, 510632, People's Republic of China.

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http://dx.doi.org/10.1038/s41598-017-13407-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635028PMC
October 2017

Modulation of the Nur77-Bcl-2 apoptotic pathway by p38α MAPK.

Oncotarget 2017 Sep 13;8(41):69731-69745. Epub 2017 Jul 13.

School of Pharmaceutical Sciences, Fujian Provincial Key Laboratory of Innovative Drug Target Research, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.18632/oncotarget.19227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642512PMC
September 2017

Characterization of Methyltransferase AlmCII in Chalcomycin Biosynthesis: The First TylF Family O-Methyltransferase Works on a 4'-Deoxysugar.

Chembiochem 2017 08 28;18(15):1510-1517. Epub 2017 Jun 28.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, No. 601 Huangpu Avenue, Guangzhou, 510632, P. R. China.

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http://dx.doi.org/10.1002/cbic.201700216DOI Listing
August 2017

Synthesis of MeON-neoglycosides of digoxigenin with 6-deoxy- and 2,6-dideoxy-d-glucose derivatives and their anticancer activity.

Bioorg Med Chem Lett 2017 08 3;27(15):3359-3364. Epub 2017 Jun 3.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.06.008DOI Listing
August 2017

Development of a versatile and conventional technique for gene disruption in filamentous fungi based on CRISPR-Cas9 technology.

Sci Rep 2017 08 23;7(1):9250. Epub 2017 Aug 23.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, 510632, China.

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http://dx.doi.org/10.1038/s41598-017-10052-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569088PMC
August 2017

Neuroprotective effects of total flavonoid fraction of the Epimedium koreanum Nakai extract on dopaminergic neurons: In vivo and in vitro.

Biomed Pharmacother 2017 Jul 8;91:656-663. Epub 2017 May 8.

Department of Physiology, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders and State Key Disciplines, Medical College of Qingdao University, Qingdao 266071, PR China; Shandong Provincial Collaborative Innovation Center for Neurodegenerative Disorders, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2017.04.083DOI Listing
July 2017

Six new sesquiterpenoids from Nardostachys chinensis Batal.

Fitoterapia 2017 Jun 5;119:75-82. Epub 2017 Apr 5.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2017.04.004DOI Listing
June 2017

[Simultaneous determination of cordycepin and 2'-deoxyadenosine in Cordyceps genus by online SPE-HPLC].

Zhongguo Zhong Yao Za Zhi 2017 May;42(10):1932-1938

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20170223.025DOI Listing
May 2017

A microbial model of mammalian metabolism: biotransformation of 4,5-dimethoxyl-canthin-6-one using Cunninghamella blakesleeana CGMCC 3.970.

Xenobiotica 2017 Apr 30;47(4):284-289. Epub 2016 May 30.

a Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University , Guangzhou , P.R. China.

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http://dx.doi.org/10.1080/00498254.2016.1184774DOI Listing
April 2017

Delivery of acetylthevetin B, an antitumor cardiac glycoside, using polymeric micelles for enhanced therapeutic efficacy against lung cancer cells.

Acta Pharmacol Sin 2017 Feb 5;38(2):290-300. Epub 2016 Dec 5.

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

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http://dx.doi.org/10.1038/aps.2016.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309751PMC
February 2017

Polyphenols from wolfberry and their bioactivities.

Food Chem 2017 Jan 19;214:644-654. Epub 2016 Jul 19.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2016.07.105DOI Listing
January 2017

A new hetero dimeric terpenoid derivative, japonicaside C, from the flower buds of Lonicera japonica.

Nat Prod Res 2017 Jan 30;31(2):143-148. Epub 2016 Aug 30.

b Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy , Jinan University , Guangzhou , P.R. China.

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http://dx.doi.org/10.1080/14786419.2016.1219859DOI Listing
January 2017

Chiral separation and absolute configurations of two pairs of racemic polyprenylated benzophenones from Hypericum sampsonii.

Fitoterapia 2017 Jan 4;116:39-44. Epub 2016 Nov 4.

Institute of Traditional Chinese Medicine & Natural Products, Jinan University, China; College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2016.10.014DOI Listing
January 2017

Dimericbiscognienyne A: A Meroterpenoid Dimer from Biscogniauxia sp. with New Skeleton and Its Activity.

Org Lett 2017 01 9;19(1):38-41. Epub 2016 Dec 9.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.

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http://dx.doi.org/10.1021/acs.orglett.6b03264DOI Listing
January 2017

Three new triterpenoid saponins from the roots of Ardisia crenata and their cytotoxic activities.

Nat Prod Res 2016 Dec 7;30(23):2694-2703. Epub 2016 Mar 7.

c Department of Natural Products Chemistry , Shenyang Pharmaceutical University , Shenyang , P.R. China.

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http://dx.doi.org/10.1080/14786419.2016.1146889DOI Listing
December 2016

Discovery of a New Class of Cathepsin K Inhibitors in Rhizoma Drynariae as Potential Candidates for the Treatment of Osteoporosis.

Int J Mol Sci 2016 Dec 16;17(12). Epub 2016 Dec 16.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.

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http://www.mdpi.com/1422-0067/17/12/2116
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http://dx.doi.org/10.3390/ijms17122116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187916PMC
December 2016

Aldgamycins J-O, 16-Membered Macrolides with a Branched Octose Unit from Streptomycetes sp. and Their Antibacterial Activities.

J Nat Prod 2016 10 30;79(10):2446-2454. Epub 2016 Sep 30.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.

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http://dx.doi.org/10.1021/acs.jnatprod.6b00200DOI Listing
October 2016

Cardiac glycosides from the seeds of Thevetia peruviana and their pro-apoptotic activity toward cancer cells.

J Asian Nat Prod Res 2016 Sep 18;18(9):837-47. Epub 2016 Apr 18.

b College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang 110016 , China.

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http://dx.doi.org/10.1080/10286020.2016.1170814DOI Listing
September 2016

Three Pairs of New Isopentenyl Dibenzo[b,e]oxepinone Enantiomers from Talaromyces flavus, a Wetland Soil-Derived Fungus.

Molecules 2016 Sep 7;21(9). Epub 2016 Sep 7.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.

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http://dx.doi.org/10.3390/molecules21091184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274342PMC
September 2016

Phytochemicals and potential health effects of Sambucus williamsii Hance (Jiegumu).

Chin Med 2016 28;11:36. Epub 2016 Jul 28.

State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), Shenzhen Research Institute of The Hong Kong Polytechnic University, Shenzhen, 518057 China ; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.1186/s13020-016-0106-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965893PMC
August 2016

A Single Gene Cluster for Chalcomycins and Aldgamycins: Genetic Basis for Bifurcation of Their Biosynthesis.

Chembiochem 2016 07 18;17(13):1241-9. Epub 2016 May 18.

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, No. 103 Wenhua Road, Shenyang, 110016, China.

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http://dx.doi.org/10.1002/cbic.201600118DOI Listing
July 2016

Anticancer activities of proanthocyanidins from the plant Urceola huaitingii and their synergistic effects in combination with chemotherapeutics.

Fitoterapia 2016 Jul 27;112:175-82. Epub 2016 May 27.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2016.05.015DOI Listing
July 2016

Adeninealkylresorcinol, the first alkylresorcinol tethered with nucleobase from Lasiodiplodia sp.

Fitoterapia 2016 Jul 23;112:254-9. Epub 2016 Jun 23.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0367326X163013
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http://dx.doi.org/10.1016/j.fitote.2016.06.011DOI Listing
July 2016

Phytochemistry and pharmacology of Allii Macrostemonis Bulbus, a traditional Chinese medicine.

Chin J Nat Med 2016 Jul;14(7):481-98

College of Pharmacy, Jinan University, Guangzhou 510632, China; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau, China. Electronic address:

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http://dx.doi.org/10.1016/S1875-5364(16)30058-9DOI Listing
July 2016

Bioactive Nitrogenous Compounds from Acorus tatarinowii.

Magn Reson Chem 2016 May 7;54(5):396-9. Epub 2015 Dec 7.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou, 510632, China.

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http://dx.doi.org/10.1002/mrc.4393DOI Listing
May 2016

Biosynthesis of LL-Z1272β: Discovery of a New Member of NRPS-like Enzymes for Aryl-Aldehyde Formation.

Chembiochem 2016 May 9;17(10):904-7. Epub 2016 Apr 9.

Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1002/cbic.201600087DOI Listing
May 2016

Rapid characterization of Ziziphi Spinosae Semen by UPLC/Qtof MS with novel informatics platform and its application in evaluation of two seeds from Ziziphus species.

J Pharm Biomed Anal 2016 Apr 23;122:59-80. Epub 2016 Jan 23.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2016.01.047DOI Listing
April 2016

Isolation and identification of metabolites of bakuchiol in rats.

Fitoterapia 2016 Mar 14;109:31-8. Epub 2015 Nov 14.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2015.11.006DOI Listing
March 2016

New antibacterial isocoumarin glycosides from a wetland soil derived fungal strain Metarhizium anisopliae.

Bioorg Med Chem Lett 2016 Mar 28;26(5):1391-6. Epub 2016 Jan 28.

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.01.074DOI Listing
March 2016

Lycibarbarspermidines A-O, New Dicaffeoylspermidine Derivatives from Wolfberry, with Activities against Alzheimer's Disease and Oxidation.

J Agric Food Chem 2016 Mar 8;64(11):2223-37. Epub 2016 Mar 8.

Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, ‡Department of Immunobiology, Institute of Tissue Transplantation and Immunology, College of Life Science and Technology, and §Guangdong Medical Key Laboratory of Brain Function and Diseases, GMH Institute of Central Nervous System Regeneration, Jinan University , Guangzhou 510632, PR China.

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http://dx.doi.org/10.1021/acs.jafc.5b05274DOI Listing
March 2016

Novel phthalide derivatives identified from Ligusticum chuanxiong (Chuanxiong).

Chin Med 2016 8;11:10. Epub 2016 Mar 8.

Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou, China.

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http://dx.doi.org/10.1186/s13020-016-0080-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782370PMC
March 2016

Study on chemical profiles and metabolites of Allii Macrostemonis Bulbus as well as its representative steroidal saponins in rats by ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry.

Food Chem 2016 Feb 9;192:499-515. Epub 2015 Jul 9.

College of Pharmacy, Jinan University, Guangzhou 510632, PR China; College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2015.07.040DOI Listing
February 2016

Comparative study of two types of herbal capsules with different species for the prevention of ovariectomised-induced osteoporosis in rats.

J Orthop Translat 2016 Jan 29;4:14-27. Epub 2015 Aug 29.

Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, PR China.

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http://dx.doi.org/10.1016/j.jot.2015.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987012PMC
January 2016

RXRα transcriptional inhibitors from the stems of Calophyllum membranaceum.

Fitoterapia 2016 Jan 11;108:66-72. Epub 2015 Nov 11.

College of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, PR China; Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2015.11.001DOI Listing
January 2016

Same data, different structures: diastereoisomers with substantially identical NMR data from nature.

Chem Commun (Camb) 2016 Jan;52(6):1250-3

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China.

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http://dx.doi.org/10.1039/c5cc07141kDOI Listing
January 2016

Cardiac Glycosides from the Seeds of Thevetia peruviana.

J Nat Prod 2016 Jan 29;79(1):38-50. Epub 2015 Dec 29.

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang 110016, People's Republic of China.

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http://dx.doi.org/10.1021/acs.jnatprod.5b00611DOI Listing
January 2016

Two new phenylpropanoids and one new sesquiterpenoid from the bioactive fraction of Sambucus williamsii.

J Asian Nat Prod Res 2015 5;17(6):625-32. Epub 2015 Jun 5.

a Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University , Guangzhou , China.

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http://dx.doi.org/10.1080/10286020.2015.1046448DOI Listing
November 2015

Pericolactines A-C, a New Class of Diterpenoid Alkaloids with Unusual Tetracyclic Skeleton.

Sci Rep 2015 Nov 27;5:17082. Epub 2015 Nov 27.

Institute of Traditional Chinese Medicine &Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China.

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http://www.nature.com/articles/srep17082
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http://dx.doi.org/10.1038/srep17082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661464PMC
November 2015

Nodulisporisteroids C-L, new 4-methyl-progesteroid derivatives from Nodulisporium sp.

Steroids 2015 Oct 6;102:101-9. Epub 2015 Aug 6.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.steroids.2015.08.004DOI Listing
October 2015

¹H and ¹³C NMR spectral assignments of 2-pyrone derivatives from an endophytic fungus of sarcosomataceae.

Magn Reson Chem 2015 Oct 10;53(10):866-71. Epub 2015 Aug 10.

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, PR China.

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http://dx.doi.org/10.1002/mrc.4282DOI Listing
October 2015

Stachybisbins A and B, the first cases of seco-bisabosquals from Stachybotrys bisbyi.

Fitoterapia 2015 Sep 3;105:151-5. Epub 2015 Jul 3.

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2015.06.022DOI Listing
September 2015

[Two new polyesters from wetland soil-derived fungus Talaromyces flavus].

Zhongguo Zhong Yao Za Zhi 2015 Sep;40(17):3347-51

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September 2015

Spiroalkaloids from Shensong Yangxin capsule.

J Asian Nat Prod Res 2015 May;17(5):559-66

a Guangdong Institute for Food and Drug Control , Guangzhou 510180 , China.

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http://dx.doi.org/10.1080/10286020.2015.1047354DOI Listing
May 2015