Publications by authors named "Xin Hu"

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MNPs@anionic MOFs/ERGO with the size selectivity for the electrochemical determination of HO released from living cells.
Biosens Bioelectron 2018 Sep 26;116:81-88. Epub 2018 May 26.
The State Key Laboratory of Natural and Biomimetic Drugs and School of Pharmaceutical Sciences, Peking University, Beijing 100191, People's Republic of China. Electronic address:

PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
Cancer Res 2018 Jun 26;78(12):3190-3206. Epub 2018 Apr 26.
Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.

Simultaneous determination of cyclosporine and tacrolimus in human whole blood by ultra-high performance liquid chromatography tandem mass spectrometry and comparison with a chemiluminescence microparticle immunoassay.
J Chromatogr B Analyt Technol Biomed Life Sci 2018 Jun 13;1087-1088:36-42. Epub 2018 Apr 13.
Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, 6 Tiantan Xili, Dongcheng District, Beijing 100050, PR China; Department of Clinical Pharmacology, College of Pharmaceutical Sciences, Capital Medical University, Beijing 100045, PR China. Electronic address:


Enzymatic Continuous Flow Synthesis of Thiol-Terminated Poly(δ-Valerolactone) and Block Copolymers.
Macromol Rapid Commun 2018 Apr 16;39(8):e1700807. Epub 2018 Feb 16.
College of Biotechnology and Pharmaceutical Engineering, State Key Laboratory of Materials-Oriented Chemical Engineering, Jiangsu National Synergetic Innovation Centre for Advanced Materials, Nanjing Tech University, Nanjing, 211800, China.

Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.
J Med Chem 2018 Apr 23;61(7):3193-3208. Epub 2018 Mar 23.
Department of Molecular and Cellular Oncology , The University of Texas MD Anderson Cancer Center , Houston , Texas 77030 , United States.

In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis.
Proc Natl Acad Sci U S A 2018 Apr 9;115(17):E3978-E3986. Epub 2018 Apr 9.
State Key Laboratory of Cell Biology, Innovation Center for Cell Signaling Network, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China;

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients.
Nat Commun 2018 Apr 10;9(1):1357. Epub 2018 Apr 10.
Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.

IL6 blockade potentiates the anti-tumor effects of γ-secretase inhibitors in Notch3-expressing breast cancer.
Cell Death Differ 2018 Feb 13;25(2):330-339. Epub 2017 Oct 13.
Key Laboratory of Breast Cancer in Shanghai, Cancer Institute, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China.


Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro.
J Pharmacol Exp Ther 2018 Jan 31;364(1):38-45. Epub 2017 Oct 31.
Laboratory of Endocrinology and Receptor Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland (S.N., E.E., A.B., S.J.M., M.C.G.); and Division of Pre-Clinical Innovations, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (E.B., M.F., N.S., D.K., X.H., J.J.M.).



Effects of copyrolysis of sludge with calcium carbonate and calcium hydrogen phosphate on chemical stability of carbon and release of toxic elements in the resultant biochars.
Chemosphere 2017 Dec 8;189:76-85. Epub 2017 Sep 8.
State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering and Center of Material Analysis, 20 Hankou Road, Nanjing University, Nanjing 210093, PR China.

Outcome and risk factors associated with extent of central nervous system injury due to exertional heat stroke.
Medicine (Baltimore) 2017 Nov;96(44):e8417
aDepartment of Critical Care Medicine, Chinese PLA General Hospital, Beijing bDepartment of Orthopedics, Wuhan General Hospital of Guangzhou Command, Guangzhou cDepartment of Critical Care Medicine, Kai Luan General Hospital, Tangshan dDepartment of Critical Care Medicine, The Centre Hospital of Baotou, Baotou eDepartment of Critical Care Medicine, The 251th Hospital of Chinese PLA, Zhangjiakou fDepartment of Critical Care Medicine, The 180th Hospital of Chinese PLA, Quanzhou gDepartment of Critical Care Medicine, People's Hospital Chang Ji Hui Autonomous Prefecture, Xinjiang hDepartment of Critical Care Medicine, Affiliated Hospital of Nan Tong University, Nantong, China iDepartment of Emergency Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.


Development of an Aryloxazole Class of Hepatitis C Virus Inhibitors Targeting the Entry Stage of the Viral Replication Cycle.
J Med Chem 2017 Jul 13;60(14):6364-6383. Epub 2017 Jul 13.
University of Kansas Specialized Chemistry Center, University of Kansas , Lawrence, Kansas 66047, United States.

Menin enhances c-Myc-mediated transcription to promote cancer progression.
Nat Commun 2017 May 5;8:15278. Epub 2017 May 5.
CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Science, University of Science and Technology of China, Hefei, Anhui 230027, China.

PTK7 is a novel oncogenic target for esophageal squamous cell carcinoma.
World J Surg Oncol 2017 May 25;15(1):105. Epub 2017 May 25.
Institute of Tissue Engineering and Stem Cells, The Second Clinical Medical College of North Sichuan Medical College, Nanchong Central Hospital, 637000, Nanchong, Sichuan Province, People's Republic of China.

Impact of hormone receptor status and distant recurrence-free interval on survival benefits from trastuzumab in HER2-positive metastatic breast cancer.
Sci Rep 2017 04 25;7(1):1134. Epub 2017 Apr 25.
Department of Breast Surgery, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.

Establishment and characterization of primary astrocyte culture from adult mouse brain.
Brain Res Bull 2017 06 10;132:10-19. Epub 2017 May 10.
Institute of Neuroscience, Key Laboratory of Molecular Neurobiology of Ministry of Education and the Collaborative Innovation Center for Brain Science, Second Military Medical University, Shanghai, China. Electronic address:

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.
Cancer Cell 2017 07;32(1):42-56.e6
Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. Electronic address:

Increased Number of Beam Angles Is Associated With Higher Cardiac Dose in Adjuvant Fixed Gantry Intensity Modulated Radiation Therapy of Left-Sided Breast Cancer.
Int J Radiat Oncol Biol Phys 2017 12 27;99(5):1137-1145. Epub 2017 Jun 27.
Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut; Cancer Outcomes, Public Policy and Effectiveness Research Center, Yale School of Medicine, New Haven, Connecticut.

Radiation dose and cardiac risk in breast cancer treatment: An analysis of modern radiation therapy including community settings.
Pract Radiat Oncol 2018 May - Jun;8(3):e79-e86. Epub 2017 Jul 20.
Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut; Cancer Outcomes, Public Policy and Effectiveness Research Center, Yale School of Medicine, New Haven, Connecticut. Electronic address:

Risk of myeloid neoplasms after radiotherapy among older women with localized breast cancer: A population-based study.
PLoS One 2017 13;12(9):e0184747. Epub 2017 Sep 13.
Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University, New Haven, Connecticut, United States of America.


CAPG enhances breast cancer metastasis by competing with PRMT5 to modulate STC-1 transcription.
Theranostics 2018 3;8(9):2549-2564. Epub 2018 Apr 3.
Department of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.


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