Xiaoyi Gong

Xiaoyi Gong

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Xiaoyi Gong

Xiaoyi Gong

Publications by authors named "Xiaoyi Gong"

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20Publications

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Analysis of thermolabile residual solvents in a spray dried dispersion using static headspace gas chromatography.

J Sep Sci 2019 Mar 22;42(6):1222-1229. Epub 2019 Jan 22.

Analytical Commercialization Technology, Merck & Co., Inc., Rahway, New Jersey, USA.

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http://dx.doi.org/10.1002/jssc.201801024DOI Listing
March 2019

Assessment of coulometric array electrochemical detection coupled with HPLC-UV for the absolute quantitation of pharmaceuticals.

Analyst 2017 Jan;142(3):525-536

Department of Process & Analytical Chemistry, Merck & Co., Inc., Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1039/c6an02432gDOI Listing
January 2017

Supercritical fluid chromatography for GMP analysis in support of pharmaceutical development and manufacturing activities.

J Pharm Biomed Anal 2016 Jan 15;117:316-24. Epub 2015 Sep 15.

Department of Process & Analytical Chemistry, Merck Research Laboratories, Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1016/j.jpba.2015.09.014DOI Listing
January 2016

Efficient HPLC method development using structure-based database search, physico-chemical prediction and chromatographic simulation.

J Pharm Biomed Anal 2015 Feb 8;104:49-54. Epub 2014 Nov 8.

Merck Research Laboratories, Merck, Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1016/j.jpba.2014.10.032DOI Listing
February 2015

Evaluation of a compact mass spectrometer for routine support of pharmaceutical chemistry.

J Pharm Biomed Anal 2014 Jun 29;94:139-44. Epub 2014 Jan 29.

Analytical Chemistry, Merck Research Laboratories, Rahway, NJ 07065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2014.01.029DOI Listing
June 2014

Systematic approach to conformational sampling for assigning absolute configuration using vibrational circular dichroism.

J Med Chem 2014 Jan 2;57(2):477-94. Epub 2014 Jan 2.

Merck Research Laboratories, Merck & Co., Inc., PO Box 2000, Rahway, New Jersey 07065, United States.

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http://dx.doi.org/10.1021/jm401600uDOI Listing
January 2014

Improved chiral SFC screening for analytical method development.

Chirality 2013 Nov 15;25(11):799-804. Epub 2013 Aug 15.

Analytical Chemistry, Merck Research Laboratories, Rahway, New Jersey.

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http://dx.doi.org/10.1002/chir.22218DOI Listing
November 2013

Analysis of volatile bases by high performance liquid chromatography with aerosol-based detection.

J Chromatogr A 2012 Mar 20;1229:172-9. Epub 2012 Jan 20.

Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1016/j.chroma.2012.01.036DOI Listing
March 2012

Estimating chromatographic enantioselectivity (α) from gradient enantioselective chromatography data.

Chirality 2011 Feb 27;23(2):128-32. Epub 2010 Aug 27.

Separation and Purification Center of Excellence, Merck & Co., Inc., Rahway, New Jersey, USA.

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http://doi.wiley.com/10.1002/chir.20887
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http://dx.doi.org/10.1002/chir.20887DOI Listing
February 2011

Factors influencing the interconversion of a new class of dibenzodiazepine sulfonamide atropisomers.

Chirality 2009 ;21 Suppl 1:E105-9

Merck Research Laboratories, Merck & Co., Inc., Rahway, New Jersey, USA.

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http://dx.doi.org/10.1002/chir.20785DOI Listing
May 2010

Systematic evaluation of new chiral stationary phases for supercritical fluid chromatography using a standard racemate library.

J Chromatogr A 2010 Feb 8;1217(7):1134-8. Epub 2009 Oct 8.

Separation & Purification Center of Excellence, Merck Research Laboratories, Rahway, NJ 07065, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002196730901479
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http://dx.doi.org/10.1016/j.chroma.2009.10.004DOI Listing
February 2010

Microscale HPLC enables a new paradigm for commercialization of complex chiral stationary phases.

Chirality 2008 Jul;20(7):815-9

Separation and Purification Center of Excellence, Merck & Co, Inc., Rahway, New Jersey 07065, USA.

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http://doi.wiley.com/10.1002/chir.20548
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http://dx.doi.org/10.1002/chir.20548DOI Listing
July 2008

Multiparallel microfluidic high-performance liquid chromatography for high-throughput normal-phase chiral analysis.

J Chromatogr A 2007 Mar 26;1145(1-2):149-54. Epub 2007 Jan 26.

Separation & Analysis Technologies, Merck and Co., Inc., Rahway, NJ 07065, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002196730700121
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http://dx.doi.org/10.1016/j.chroma.2007.01.067DOI Listing
March 2007

Multiparallel chiral method development screening using an 8-channel microfluidic HPLC system.

Chirality 2006 Nov;18(10):803-13

Separation & Analysis Technologies, Process Research, Merck & Co. Inc., Rahway, New Jersey 07065, USA.

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http://doi.wiley.com/10.1002/chir.20325
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http://dx.doi.org/10.1002/chir.20325DOI Listing
November 2006

Synthesis of 1-tert-butyl-4-chloropiperidine: generation of an N-tert-butyl group by the reaction of a dimethyliminium salt with methylmagnesium chloride.

J Org Chem 2005 Mar;70(5):1930-3

Department of Process Research, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, USA.

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http://dx.doi.org/10.1021/jo048047gDOI Listing
March 2005

Aligned nanotubes.

Chemphyschem 2003 Nov;4(11):1150-69

Department of Polymer Engineering, College of Polymer Science and Polymer Engineering, University of Akron, Akron, OH44325-0301, USA.

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http://dx.doi.org/10.1002/cphc.200300770DOI Listing
November 2003