Xiaoquan Wen

Xiaoquan Wen

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Xiaoquan Wen

Xiaoquan Wen

Publications by authors named "Xiaoquan Wen"

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35Publications

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False discovery control for penalized variable selections with high-dimensional covariates.

Stat Appl Genet Mol Biol 2018 12 15;17(6). Epub 2018 Dec 15.

Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1515/sagmb-2018-0038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450074PMC
December 2018

High-throughput characterization of genetic effects on DNA-protein binding and gene transcription.

Genome Res 2018 11 25;28(11):1701-1708. Epub 2018 Sep 25.

Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1101/gr.237354.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211638PMC
November 2018

QuASAR-MPRA: accurate allele-specific analysis for massively parallel reporter assays.

Bioinformatics 2018 03;34(5):787-794

Center for Molecular Medicine and Genetics, School of Medicine, Wayne State University, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1093/bioinformatics/btx598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049023PMC
March 2018

Environmental perturbations lead to extensive directional shifts in RNA processing.

PLoS Genet 2017 Oct 12;13(10):e1006995. Epub 2017 Oct 12.

Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667937PMC
October 2017

Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization.

PLoS Genet 2017 Mar 9;13(3):e1006646. Epub 2017 Mar 9.

Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363995PMC
March 2017

Efficient Integrative Multi-SNP Association Analysis via Deterministic Approximation of Posteriors.

Am J Hum Genet 2016 06 26;98(6):1114-1129. Epub 2016 May 26.

Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI 48201, USA; Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1016/j.ajhg.2016.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908152PMC
June 2016

Which Genetics Variants in DNase-Seq Footprints Are More Likely to Alter Binding?

PLoS Genet 2016 Feb 22;12(2):e1005875. Epub 2016 Feb 22.

Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764260PMC
February 2016

Bayesian model comparison in genetic association analysis: linear mixed modeling and SNP set testing.

Authors:
Xiaoquan Wen

Biostatistics 2015 Oct 21;16(4):701-12. Epub 2015 Mar 21.

Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1093/biostatistics/kxv009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570575PMC
October 2015

QuASAR: quantitative allele-specific analysis of reads.

Bioinformatics 2015 Apr 4;31(8):1235-42. Epub 2014 Dec 4.

Center for Molecular Medicine and Genetics, Department of Obstetrics and Gynecology, Wayne State University, 540 E Canfield, Scott Hall, Detroit, MI 48201, USA and Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393517PMC
April 2015

Cross-population joint analysis of eQTLs: fine mapping and functional annotation.

PLoS Genet 2015 Apr 23;11(4):e1005176. Epub 2015 Apr 23.

Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, USA; Department of Clinical and Translational Sciences, Wayne State University, Detroit, MI, USA.

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http://dx.doi.org/10.1371/journal.pgen.1005176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408026PMC
April 2015

The role of environmental heterogeneity in meta-analysis of gene-environment interactions with quantitative traits.

Genet Epidemiol 2014 Jul 6;38(5):416-29. Epub 2014 May 6.

Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.

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http://dx.doi.org/10.1002/gepi.21810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108593PMC
July 2014

Bayesian model selection in complex linear systems, as illustrated in genetic association studies.

Authors:
Xiaoquan Wen

Biometrics 2014 Mar 18;70(1):73-83. Epub 2013 Dec 18.

Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, U.S.A.

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http://dx.doi.org/10.1111/biom.12112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954315PMC
March 2014

BAYESIAN METHODS FOR GENETIC ASSOCIATION ANALYSIS WITH HETEROGENEOUS SUBGROUPS: FROM META-ANALYSES TO GENE-ENVIRONMENT INTERACTIONS.

Ann Appl Stat 2014;8(1):176-203

Department of Statistics and Department of Human Genetics, University of Chicago, 5734 S. University Avenue, Chicago, IL 60637, USA.

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http://projecteuclid.org/euclid.aoas/1396966283
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http://dx.doi.org/10.1214/13-AOAS695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583155PMC
January 2014

A statistical framework for joint eQTL analysis in multiple tissues.

PLoS Genet 2013 May 9;9(5):e1003486. Epub 2013 May 9.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649995PMC
May 2013

USING LINEAR PREDICTORS TO IMPUTE ALLELE FREQUENCIES FROM SUMMARY OR POOLED GENOTYPE DATA.

Ann Appl Stat 2010 Sep;4(3):1158-1182

Department of Statistics, University of Chicago, Chicago, IL 60637, USA,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072818PMC
September 2010

Gene, region and pathway level analyses in whole-genome studies.

Genet Epidemiol 2010 Apr;34(3):222-231

Department of Statistics, The University of Chicago, 5734 S. University Ave., Chicago, IL 60637.

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http://doi.wiley.com/10.1002/gepi.20452
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http://dx.doi.org/10.1002/gepi.20452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061611PMC
April 2010

Broad-scale recombination patterns underlying proper disjunction in humans.

PLoS Genet 2009 Sep 18;5(9):e1000658. Epub 2009 Sep 18.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1000658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734982PMC
September 2009

[Cartilage tissue engineering with acellular cartilage matrix as scaffold in rabbit model].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2008 Jul;22(7):846-50

Division of Plastic Surgery, Xinhua Hospital of Dalian University, Dalian Liaoning, 116021, PR China.

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July 2008

High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans.

Science 2008 Mar 31;319(5868):1395-8. Epub 2008 Jan 31.

Department of Human Genetics, University of Chicago, 920 East 58th Street, Cummings Life Science Center, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1126/science.1151851DOI Listing
March 2008

Association studies for untyped markers with TUNA.

Bioinformatics 2008 Feb 5;24(3):435-7. Epub 2007 Dec 5.

Department of Statistics, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/bioinformatics/btm603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051297PMC
February 2008

A worldwide survey of haplotype variation and linkage disequilibrium in the human genome.

Nat Genet 2006 Nov 22;38(11):1251-60. Epub 2006 Oct 22.

Department of Human Genetics, University of Chicago, 920 East 58th Street, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1038/ng1911DOI Listing
November 2006

Coverage and characteristics of the Affymetrix GeneChip Human Mapping 100K SNP set.

PLoS Genet 2006 May 5;2(5):e67. Epub 2006 May 5.

Department of Statistics, The University of Chicago, Chicago, Illinois, USA.

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https://dx.plos.org/10.1371/journal.pgen.0020067
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http://dx.doi.org/10.1371/journal.pgen.0020067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456318PMC
May 2006

A map of recent positive selection in the human genome.

PLoS Biol 2006 Mar 7;4(3):e72. Epub 2006 Mar 7.

Department of Human Genetics, University of Chicago, Chicago, Illinois, USA.

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https://dx.plos.org/10.1371/journal.pbio.0040072
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http://dx.doi.org/10.1371/journal.pbio.0040072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1382018PMC
March 2006

Association mapping and fine mapping with TreeLD.

Bioinformatics 2005 Jul 26;21(14):3168-70. Epub 2005 Apr 26.

Department of Human Genetics, The University of Chicago 920 East 58th Street-CLSC 507, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/bioinformatics/bti453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587010PMC
July 2005

Evidence for extensive transmission distortion in the human genome.

Am J Hum Genet 2004 Jan 15;74(1):62-72. Epub 2003 Dec 15.

Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1181913PMC
http://dx.doi.org/10.1086/381131DOI Listing
January 2004