Xiaolong Wan

Xiaolong Wan

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Xiaolong Wan

Xiaolong Wan

Publications by authors named "Xiaolong Wan"

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Inhibition of CTRP6 prevented survival and migration in hepatocellular carcinoma through inactivating the AKT signaling pathway.

J Cell Biochem 2019 Oct 20;120(10):17059-17066. Epub 2019 May 20.

Department of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

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http://dx.doi.org/10.1002/jcb.28967DOI Listing
October 2019

Facilitating the transmetalation step with aryl-zincates in nickel-catalyzed enantioselective arylation of secondary benzylic halides.

Nat Commun 2019 07 4;10(1):2963. Epub 2019 Jul 4.

Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy Sciences, Chinese Academy of Sciences, 345 Lingling Road, 200032, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1038/s41467-019-10851-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609707PMC
July 2019

Enantioselective Trifluoromethylalkynylation of Alkenes via Copper-Catalyzed Radical Relay.

J Am Chem Soc 2018 09 24;140(35):10965-10969. Epub 2018 Aug 24.

State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis , Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road , Shanghai 200032 , China.

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http://dx.doi.org/10.1021/jacs.8b07436DOI Listing
September 2018

Asymmetric Synthesis of Silicon-Stereogenic Vinylhydrosilanes by Cobalt-Catalyzed Regio- and Enantioselective Alkyne Hydrosilylation with Dihydrosilanes.

Angew Chem Int Ed Engl 2018 05 25;57(21):6319-6323. Epub 2018 Apr 25.

State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Rd, Shanghai, 200032, China.

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http://dx.doi.org/10.1002/anie.201802806DOI Listing
May 2018

Copper-Catalyzed Highly Stereoselective Trifluoromethylation and Difluoroalkylation of Secondary Propargyl Sulfonates.

Angew Chem Int Ed Engl 2018 03 21;57(12):3187-3191. Epub 2018 Feb 21.

Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai, 200032, China.

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http://dx.doi.org/10.1002/anie.201711463DOI Listing
March 2018

Enantioselective Construction of Trifluoromethoxylated Stereogenic Centers by a Nickel-Catalyzed Asymmetric Suzuki-Miyaura Coupling of Secondary Benzyl Bromides.

Angew Chem Int Ed Engl 2017 09 21;56(39):11986-11989. Epub 2017 Aug 21.

Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.

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http://dx.doi.org/10.1002/anie.201706868DOI Listing
September 2017

Asymmetric Copper-Catalyzed Intermolecular Aminoarylation of Styrenes: Efficient Access to Optical 2,2-Diarylethylamines.

J Am Chem Soc 2017 05 10;139(20):6811-6814. Epub 2017 May 10.

State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.

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http://dx.doi.org/10.1021/jacs.7b02455DOI Listing
May 2017

Asymmetric Cu-Catalyzed Intermolecular Trifluoromethylarylation of Styrenes: Enantioselective Arylation of Benzylic Radicals.

J Am Chem Soc 2017 03 21;139(8):2904-2907. Epub 2017 Feb 21.

State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.

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http://dx.doi.org/10.1021/jacs.6b13299DOI Listing
March 2017

Enantioselective Copper-Catalyzed Intermolecular Cyanotrifluoromethylation of Alkenes via Radical Process.

J Am Chem Soc 2016 12 21;138(48):15547-15550. Epub 2016 Nov 21.

State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 345 Lingling Road, Shanghai, China , 200032.

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http://pubs.acs.org/doi/10.1021/jacs.6b10468
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http://dx.doi.org/10.1021/jacs.6b10468DOI Listing
December 2016

Enantioselective Bromo-oxycyclization of Silanol.

Org Lett 2016 Jan 14;18(1):80-3. Epub 2015 Dec 14.

Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Science, Northwest A&F University , 22 Xinong Road, Yangling 712100, Shaanxi, China.

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http://dx.doi.org/10.1021/acs.orglett.5b03303DOI Listing
January 2016

Chiral ion-pair organocatalyst promotes highly enantioselective 3- iodo-cycloetherification of allyl alcohols.

Chem Sci 2015 Dec 27;6(12):6986-6990. Epub 2015 Aug 27.

Shaanxi Key Laboratory of Natural Products & Chemical Biology , College of Science , Northwest A&F University , 22 Xinong Road , Yangling 712100 , China . Email:

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http://dx.doi.org/10.1039/c5sc02485dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947518PMC
December 2015

Total Synthesis of (-)-Conolutinine.

Org Lett 2015 Sep 28;17(18):4428-31. Epub 2015 Aug 28.

Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Science, Northwest A&F University , 22 Xinong Road, Yangling 712100, Shaanxi, China.

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http://dx.doi.org/10.1021/acs.orglett.5b02046DOI Listing
September 2015

Synthesis of naked amino-pyrroloindoline via direct aminocyclization of tryptamine.

Org Biomol Chem 2015 May;13(19):5381-4

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China.

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http://dx.doi.org/10.1039/c5ob00546aDOI Listing
May 2015

Cobalt-catalyzed enantioselective hydroboration of 1,1-disubstituted aryl alkenes.

J Am Chem Soc 2014 Nov 21;136(44):15501-4. Epub 2014 Oct 21.

State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry , 345 Lingling Road, Shanghai 200032, China.

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http://dx.doi.org/10.1021/ja5093908DOI Listing
November 2014

Ni-catalyzed asymmetric reductive allylation of aldehydes with allylic carbonates.

Chem Commun (Camb) 2014 Apr 4;50(29):3827-30. Epub 2014 Mar 4.

Department of Chemistry, Innovative Drug Research Center, and School of Materials Science and Engineering, Shanghai University, 99 Shang-Da Road, Shanghai 200444, China.

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http://dx.doi.org/10.1039/c3cc49859jDOI Listing
April 2014

Highly asymmetric bromocyclization of tryptophol: unexpected accelerating effect of DABCO-derived bromine complex.

Org Lett 2014 Apr 25;16(7):1908-11. Epub 2014 Mar 25.

State Key Laboratory of Natural Medicines, Center of Drug Discovery, China Pharmaceutical University , 24 Tongjiaxiang, Nanjing 210009, China.

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http://dx.doi.org/10.1021/ol5004109DOI Listing
April 2014

Highly enantioselective bromocyclization of tryptamines and its application in the synthesis of (-)-chimonanthine.

Angew Chem Int Ed Engl 2013 Dec 10;52(49):12924-7. Epub 2013 Oct 10.

State Key Laboratory of Bioorganic & Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032 (China).

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http://dx.doi.org/10.1002/anie.201306774DOI Listing
December 2013

Novel hybrids of optically active ring-opened 3-n-butylphthalide derivative and isosorbide as potential anti-ischemic stroke agents.

J Med Chem 2013 Apr 2;56(7):3078-89. Epub 2013 Apr 2.

State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, PR China.

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http://dx.doi.org/10.1021/jm4001693DOI Listing
April 2013

Enantioselective synthesis of cyclopropanes that contain fluorinated tertiary stereogenic carbon centers: a chiral α-fluoro carbanion strategy.

Angew Chem Int Ed Engl 2012 Jul 11;51(28):6966-70. Epub 2012 Jun 11.

Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, China.

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http://dx.doi.org/10.1002/anie.201202451DOI Listing
July 2012

Efficient total synthesis of marine alkaloid (-)-nakadomarin A.

Chemistry 2011 Nov 29;17(45):12569-72. Epub 2011 Sep 29.

Hefei National Laboratory for Physical Science at Microscale and Department of Chemistry, University of Science and Technology of China, Hefei, P.R. China.

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http://dx.doi.org/10.1002/chem.201102101DOI Listing
November 2011

Rational design of 2-pyrrolinones as inhibitors of HIV-1 integrase.

Bioorg Med Chem Lett 2011 Nov 20;21(22):6724-7. Epub 2011 Sep 20.

Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, PR China.

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http://dx.doi.org/10.1016/j.bmcl.2011.09.054DOI Listing
November 2011

Chiral N-heterocyclic carbene catalyzed annulation of α,β-unsaturated aldehydes with 1,3-dicarbonyls.

Chem Commun (Camb) 2011 Aug 27;47(30):8670-2. Epub 2011 Jun 27.

Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.

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http://dx.doi.org/10.1039/c1cc12778kDOI Listing
August 2011

Enantioselective Friedel-Crafts alkylation of indoles with trifluoroethylidene malonates by copper-bis(oxazoline) complexes: construction of trifluoromethyl-substituted stereogenic tertiary carbon center.

J Org Chem 2011 Apr 4;76(7):2282-5. Epub 2011 Mar 4.

Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, 345 Lingling Rd., Shanghai, 200032, China.

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http://dx.doi.org/10.1021/jo1024333DOI Listing
April 2011

Pd(OAc)(2) catalyzed olefination of highly electron-deficient perfluoroarenes.

J Am Chem Soc 2010 Apr;132(13):4506-7

Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.

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http://dx.doi.org/10.1021/ja908434eDOI Listing
April 2010