Xiaolan Shen

Xiaolan Shen

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Xiaolan Shen

Xiaolan Shen

Publications by authors named "Xiaolan Shen"

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32Publications

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Early echocardiographic predictors of outcomes in the mouse transverse aortic constriction heart failure model.

J Pharmacol Toxicol Methods 2017 Mar - Apr;84:93-101. Epub 2016 Dec 9.

In Vivo Pharmacology, MRL, Kenilworth, NJ, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vascn.2016.12.001DOI Listing
July 2017

Duodenal-jejunal bypass surgery induces hepatic lipidomic alterations associated with ameliorated hepatic steatosis in mice.

Obesity (Silver Spring) 2016 09 26;24(9):1938-45. Epub 2016 Jul 26.

Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, New Jersey, USA.

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http://dx.doi.org/10.1002/oby.21583DOI Listing
September 2016

Molecular characterization of cultivated bromeliad accessions with Inter-Simple Sequence Repeat (ISSR) Markers.

Int J Mol Sci 2012 18;13(5):6040-52. Epub 2012 May 18.

Flower Research and Development Centre, Zhejiang Academy of Agricutural Sciences, Hangzhou 311202, China; E-Mails: (Y.G.); (W.W.); (X.Y.); (X.S.); (J.L.); (X.L.); (D.T.); (F.S.); (Y.Y.).

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http://dx.doi.org/10.3390/ijms13056040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382752PMC
October 2015

Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells.

Mol Endocrinol 2015 Sep 28;29(9):1243-53. Epub 2015 Jul 28.

Departments of Metabolic Disorders-Diabetes (J.S., Y.F., N.A.T., A.D.H., Y.-P.Z.) and Target Validation (J.L., H.H.Z.) and Laboratory of Animal Research (X.S.), Merck Research Laboratories, Rahway, New Jersey 07065; Department of Biochemistry (M.P.K., M.R., M.S., A.D.A.), University of Wisconsin, Madison, Wisconsin 53076; Sarah W. Stedman Nutrition and Metabolism Center (H.E.H., C.B.N.), Duke University Medical Center, Durham, North Carolina 27704; and Department of Surgery/Transplant (Y.W.), University of Illinois at Chicago, Chicago, Illinois 60612.

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https://academic.oup.com/mend/article-lookup/doi/10.1210/me.
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http://dx.doi.org/10.1210/me.2014-1335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552436PMC
September 2015

Lymphatic absorption, metabolism, and excretion of a therapeutic peptide in dogs and rats.

Drug Metab Dispos 2013 Dec 2;41(12):2206-14. Epub 2013 Oct 2.

Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism (Y.Z., T.J.B., V.B.G.R.), Safety Assessment and Laboratory Animal Resources (C.A., X.S., P.K.C., B.W., T.T., A.C., X.H., C.N.N., C.V.J.), and Labeled Compound Synthesis (A.S.Z., S.J.S.), Merck Research Laboratories, Rahway, New Jersey.

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http://dx.doi.org/10.1124/dmd.113.051524DOI Listing
December 2013

Evaluation of selective inhibitors of 11β-HSD1 for the treatment of hypertension.

Bioorg Med Chem Lett 2013 Jun 22;23(12):3650-3. Epub 2013 Mar 22.

Department of Medicinal Chemistry, Merck & Co., Inc., PO Box 2000, Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1016/j.bmcl.2013.03.011DOI Listing
June 2013

Differential effects of oxyntomodulin and GLP-1 on glucose metabolism.

Am J Physiol Endocrinol Metab 2012 Jul 22;303(2):E265-71. Epub 2012 May 22.

In Vivo Pharmacology, Merck Sharp & Dohme Corporation, Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1152/ajpendo.00142.2012DOI Listing
July 2012

Lymphatic transport and catabolism of therapeutic proteins after subcutaneous administration to rats and dogs.

Drug Metab Dispos 2012 May 10;40(5):952-62. Epub 2012 Feb 10.

Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism, Merck Sharp and Dohme Corp., West Point, PA 19486, USA.

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http://dx.doi.org/10.1124/dmd.111.043604DOI Listing
May 2012

A portal vein cannulation technique for drug discovery in mice.

Lab Anim (NY) 2008 Jan;37(1):41-4

Department of Laboratory Animal Resources, Merck Research Laboratories, PO Box 2000, RY80B-100, Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1038/laban0108-41DOI Listing
January 2008

Small-molecule insulin mimetic reduces hyperglycemia and obesity in a nongenetic mouse model of type 2 diabetes.

Endocrinology 2004 Nov 5;145(11):5259-68. Epub 2004 Aug 5.

Medizinische Klinik mit Schwerpunkt Hepatologie, Gastroenterologie, Endokrinologie, und Stoffwechsel Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1210/en.2004-0610DOI Listing
November 2004

Exploring the site of anorectic action of peripherally administered synthetic melanocortin peptide MT-II in rats.

Brain Res 2003 Jul;977(2):221-30

Department of Obesity and Metabolic Research, Merck Research Laboratories, P.O. Box 2000, R80M-213, Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1016/s0006-8993(03)02683-0DOI Listing
July 2003

Effect of signal interference from dosing excipients on pharmacokinetic screening of drug candidates by liquid chromatography/mass spectrometry.

Anal Chem 2002 Dec;74(24):6305-13

Basic Chemistry and Comparative Medicine, Merck Research Laboratory, Merck & Co., Inc., P.O. Box 2000, RY800-B205, Rahway, New Jersey 07065, USA.

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http://dx.doi.org/10.1021/ac025988pDOI Listing
December 2002