Xiaojiang Xu

Xiaojiang Xu

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Xiaojiang Xu

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Mass spectrometric identification of candidate RNA-binding proteins associated with Transition Nuclear Protein mRNA in the mouse testis.

Sci Rep 2019 Sep 20;9(1):13618. Epub 2019 Sep 20.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1038/s41598-019-50052-zDOI Listing
September 2019

Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure.

J Am Heart Assoc 2019 Aug 17;8(15):e011012. Epub 2019 Jul 17.

Signal Transduction Laboratory National Institute of Environmental Health Sciences National Institutes of Health Department of Health and Human Services Research Triangle Park NC.

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http://dx.doi.org/10.1161/JAHA.118.011012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761632PMC
August 2019

Controllable organic magnetoresistance in polyaniline coated poly(p-phenylene-2,6-benzobisoxazole) short fibers.

Chem Commun (Camb) 2019 Aug;55(68):10068-10071

Shanghai Key Lab of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Shanghai 200092, People's Republic of China.

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http://dx.doi.org/10.1039/c9cc04789aDOI Listing
August 2019

Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice.

Sci Signal 2019 Apr 16;12(577). Epub 2019 Apr 16.

Signal Transduction Laboratory, NIEHS, NIH, DHHS, 111 T.W. Alexander Drive, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1126/scisignal.aau9685DOI Listing
April 2019

Endogenous glucocorticoids prevent gastric metaplasia by suppressing spontaneous inflammation.

J Clin Invest 2019 Mar 18;129(3):1345-1358. Epub 2019 Feb 18.

Molecular Endocrinology Group, Signal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1172/JCI123233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391099PMC
March 2019

A new look at survival times during cold water immersion.

J Therm Biol 2018 Dec 18;78:100-105. Epub 2018 Sep 18.

Laboratory for Exercise and Environmental Medicine, 108 Frank Kennedy, Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Manitoba, Canada R3T 2N2.

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http://dx.doi.org/10.1016/j.jtherbio.2018.08.022DOI Listing
December 2018

A retrospective analysis of 1,231 patients with anemia after surgical treatment of hyperthyroidism.

Exp Ther Med 2018 Dec 14;16(6):4664-4668. Epub 2018 Sep 14.

Department of Neck and Thoracic Surgery, 187th Hospital of People's Liberation Army, Haikou, Hainan 571100, P.R. China.

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http://www.spandidos-publications.com/10.3892/etm.2018.6738
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http://dx.doi.org/10.3892/etm.2018.6738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257823PMC
December 2018

Effect of localized microclimate heating on peripheral skin temperatures and manual dexterity during cold exposure.

J Appl Physiol (1985) 2018 11 23;125(5):1498-1510. Epub 2018 Aug 23.

United States Army Research Institute of Environmental Medicine , Natick, Massachusetts.

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http://dx.doi.org/10.1152/japplphysiol.00513.2018DOI Listing
November 2018

Estimation of core body temperature from skin temperature, heat flux, and heart rate using a Kalman filter.

Comput Biol Med 2018 08 18;99:1-6. Epub 2018 May 18.

Biophysics and Biomedical Modeling Division, U.S. Army Research Institute of Environmental Medicine, 10 General Greene Avenue, Natick, MA, 01760-5007, USA. Electronic address:

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http://dx.doi.org/10.1016/j.compbiomed.2018.05.021DOI Listing
August 2018

A superfast hexavalent chromium scavenger: Magnetic nanocarbon bridged nanomagnetite network with excellent recyclability.

J Hazard Mater 2018 Jul 10;353:166-172. Epub 2018 Apr 10.

MOE Key Laboratory of Space Applied Physics and Chemistry, Shaanxi Key Laboratory of Macromolecular Science and Technology, Department of Applied Chemistry, School of Science, Northwestern Polytechnical University, Xi' an, Shaanxi, 710072, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jhazmat.2018.03.059DOI Listing
July 2018

Estrogen Deficiency Promotes Hepatic Steatosis via a Glucocorticoid Receptor-Dependent Mechanism in Mice.

Cell Rep 2018 03;22(10):2690-2701

Signal Transduction Laboratory, National Institute of Environmental Health Sciences, NIH, Department of Health and Human Services, Research Triangle Park, NC 27709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.02.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875726PMC
March 2018

Synthesis of Fucosylated Chondroitin Sulfate Glycoclusters: A Robust Route to New Anticoagulant Agents.

Chemistry 2018 Feb 28;24(7):1694-1700. Epub 2017 Dec 28.

State Key Laboratory of Natural and Biomimetic Drugs, Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, P.R. China.

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http://dx.doi.org/10.1002/chem.201705177DOI Listing
February 2018

Generating diversity in human glucocorticoid signaling through a racially diverse polymorphism in the beta isoform of the glucocorticoid receptor.

Lab Invest 2017 11 31;97(11):1282-1295. Epub 2017 Jul 31.

Molecular Endocrinology Group, Signal Transduction Laboratory, National Institute of Environmental Health Sciences/NIH, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1038/labinvest.2017.76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759773PMC
November 2017

Reversing SKI-SMAD4-mediated suppression is essential for T17 cell differentiation.

Nature 2017 11 25;551(7678):105-109. Epub 2017 Oct 25.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1038/nature24283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743442PMC
November 2017

Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading.

Arterioscler Thromb Vasc Biol 2017 06 27;37(6):1115-1126. Epub 2017 Apr 27.

From the Division of Medical Oncology, Department of Medicine (H.T., D.H., G.C.B.) and Department of Pharmacology and Cancer Biology (G.C.B.), Duke University Medical Center, Durham, NC; Department of Pathology, Microbiology, and Immunology (T.K., A.Z.) and Department of Cancer Biology (A.Z.), Vanderbilt University, Nashville, TN; Integrative Bioinformatics, National Institute of Environmental Health Sciences, Research Triangle Park, NC (X.X.); Department of Cell Biology, Duke University School of Medicine, Durham, NC (X.G.); and Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN (A.Z.);

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http://dx.doi.org/10.1161/ATVBAHA.116.308859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444426PMC
June 2017

The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice.

EMBO Rep 2017 05 31;18(5):841-857. Epub 2017 Mar 31.

Signal Transduction Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA

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http://dx.doi.org/10.15252/embr.201643803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412809PMC
May 2017

Measured body composition and geometrical data of four "virtual family" members for thermoregulatory modeling.

Int J Biometeorol 2017 Mar 19;61(3):477-486. Epub 2016 Aug 19.

US Army Research Institute of Environmental Medicine, Biophysics and Biomedical Modeling Division, 10 General Greene Avenue, Natick, MA, 01760, USA.

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http://dx.doi.org/10.1007/s00484-016-1227-7DOI Listing
March 2017

Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development.

Curr Biol 2017 Feb 2;27(4):483-494. Epub 2017 Feb 2.

Signal Transduction Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2016.12.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319916PMC
February 2017

Glucocorticoid action in human corneal epithelial cells establishes roles for corticosteroids in wound healing and barrier function of the eye.

Exp Eye Res 2016 11 4;152:10-33. Epub 2016 Sep 4.

Signal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2016.08.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097880PMC
November 2016

Heat strain imposed by personal protective ensembles: quantitative analysis using a thermoregulation model.

Int J Biometeorol 2016 Jul 5;60(7):1065-74. Epub 2015 Dec 5.

Biophysics and Biomedical Modeling Division, US Army Research Institute of Environmental Medicine, 10 General Greene Avenue, Natick, MA, 01760, USA.

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http://link.springer.com/10.1007/s00484-015-1100-0
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http://dx.doi.org/10.1007/s00484-015-1100-0DOI Listing
July 2016

Ebola Response: Modeling the Risk of Heat Stress from Personal Protective Clothing.

PLoS One 2015 17;10(11):e0143461. Epub 2015 Nov 17.

Biophysics and Biomedical Modeling Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts, 01760, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0143461PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648492PMC
June 2016

Biophysical Assessment and Predicted Thermophysiologic Effects of Body Armor.

PLoS One 2015 22;10(7):e0132698. Epub 2015 Jul 22.

Biophysics and Biomedical Modeling Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132698PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511810PMC
April 2016

Reproductive toxicity of low level bisphenol A exposures in a two-generation zebrafish assay: Evidence of male-specific effects.

Aquat Toxicol 2015 Dec 31;169:204-14. Epub 2015 Oct 31.

Zhejiang Provincial Key Laboratory for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, China; Institute of Environmental Safety and Human Health, Wenzhou Medical University, Wenzhou 325035, China. Electronic address:

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http://dx.doi.org/10.1016/j.aquatox.2015.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689195PMC
December 2015

Fabric thermal resistance and ensemble thermal resistances are two different concepts.

J Occup Environ Hyg 2014 ;11(11):D187-8

a Biophysics and Biomedical Modeling Division , U.S. Army Research Institute of Environmental Medicine , Natick , Massachusetts.

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http://dx.doi.org/10.1080/15459624.2014.946517DOI Listing
June 2015

Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment.

PLoS One 2014 4;9(2):e87740. Epub 2014 Feb 4.

Department of Microbiology, Immunology, and Cancer Biology and Carter Immunology Center, University of Virginia School of Medicine, Charlottesville, Virginia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087740PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913631PMC
December 2014

SIRT1-mediated deacetylation of CRABPII regulates cellular retinoic acid signaling and modulates embryonic stem cell differentiation.

Mol Cell 2014 Sep 21;55(6):843-855. Epub 2014 Aug 21.

Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228935PMC
September 2014

Thermoregulatory modeling for cold stress.

Compr Physiol 2014 Jul;4(3):1057-81

Biophysics and Biomedical Modeling Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts.

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http://doi.wiley.com/10.1002/cphy.c130047
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http://dx.doi.org/10.1002/cphy.c130047DOI Listing
July 2014

Thermoregulatory modeling use and application in the military workforce.

Appl Ergon 2014 May 25;45(3):663-70. Epub 2013 Sep 25.

U.S. Army Research Institute of Environmental Medicine (USARIEM), Natick, MA, USA.

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http://dx.doi.org/10.1016/j.apergo.2013.09.010DOI Listing
May 2014

Relationship between core temperature, skin temperature, and heat flux during exercise in heat.

Eur J Appl Physiol 2013 Sep 18;113(9):2381-9. Epub 2013 Jun 18.

Biophysics and Biomedical Modeling Division, US Army Research Institute of Environmental Medicine, 42 Kansas Street, Natick, MA 01760-5007, USA.

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http://link.springer.com/content/pdf/10.1007/s00421-013-2674
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http://link.springer.com/10.1007/s00421-013-2674-z
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http://dx.doi.org/10.1007/s00421-013-2674-zDOI Listing
September 2013

Global gene expression analysis in human uterine epithelial cells defines new targets of glucocorticoid and estradiol antagonism.

Biol Reprod 2013 Sep 27;89(3):66. Epub 2013 Sep 27.

Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina.

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http://dx.doi.org/10.1095/biolreprod.113.111054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435104PMC
September 2013

Epigenetic coordination of signaling pathways during the epithelial-mesenchymal transition.

Epigenetics Chromatin 2013 Sep 2;6(1):28. Epub 2013 Sep 2.

Department of Biochemistry and Molecular Genetics, University of Virginia, 1340 Jefferson Park Ave, P.O. Box 800733, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1186/1756-8935-6-28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847279PMC
September 2013

Ultrasound extraction optimization of Acanthopanax senticosus polysaccharides and its antioxidant activity.

Int J Biol Macromol 2013 Aug 26;59:290-4. Epub 2013 Apr 26.

College of Pharmacy, Harbin Medical University, Harbin 150086, China.

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http://dx.doi.org/10.1016/j.ijbiomac.2013.04.067DOI Listing
August 2013

Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes.

Proc Natl Acad Sci U S A 2012 Dec 10;109(52):21319-24. Epub 2012 Dec 10.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1073/pnas.1218331110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535616PMC
December 2012

Determination of the cooling capacity for body ventilation system.

Eur J Appl Physiol 2011 Dec 1;111(12):3155-60. Epub 2011 Apr 1.

Biophysics and Biomedical Modeling Division, US Army Research Institute of Environmental Medicine, 42 Kansas Street, Natick, MA 01760, USA.

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http://dx.doi.org/10.1007/s00421-011-1941-0DOI Listing
December 2011

Methods of evaluating protective clothing relative to heat and cold stress: thermal manikin, biomedical modeling, and human testing.

J Occup Environ Hyg 2011 Oct;8(10):588-99

Thermal and Mountain Medicine Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760-5007, USA.

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http://dx.doi.org/10.1080/15459624.2011.613291DOI Listing
October 2011

Quantification of histone modification ChIP-seq enrichment for data mining and machine learning applications.

BMC Res Notes 2011 Aug 11;4:288. Epub 2011 Aug 11.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1186/1756-0500-4-288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170335PMC
August 2011

Sweat loss prediction using a multi-model approach.

Int J Biometeorol 2011 Jul 4;55(4):501-8. Epub 2010 Oct 4.

Biophysics and Biomedical Modeling Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA.

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http://dx.doi.org/10.1007/s00484-010-0371-8DOI Listing
July 2011

Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression.

BMC Bioinformatics 2010 Jul 23;11:396. Epub 2010 Jul 23.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1186/1471-2105-11-396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928206PMC
July 2010

Proteomic signatures of epidermal growth factor receptor and survival signal pathways correspond to gefitinib sensitivity in head and neck cancer.

Clin Cancer Res 2009 Apr 24;15(7):2361-72. Epub 2009 Mar 24.

Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-1011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689817PMC
April 2009

Gene Set Expression Comparison kit for BRB-ArrayTools.

Bioinformatics 2008 Jan 15;24(1):137-9. Epub 2007 Nov 15.

Biometric Research Branch, National Cancer Institute, 9000 Rockville Pike, Bethesda, MD 20892-7434, USA.

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http://dx.doi.org/10.1093/bioinformatics/btm541DOI Listing
January 2008

Evaluation of two cold thermoregulatory models for prediction of core temperature during exercise in cold water.

J Appl Physiol (1985) 2007 Dec 20;103(6):2034-41. Epub 2007 Sep 20.

Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760-5007, USA.

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http://jap.physiology.org/content/jap/103/6/2034.full.pdf
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http://jap.physiology.org/content/jap/early/2007/09/20/jappl
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http://jap.physiology.org/cgi/doi/10.1152/japplphysiol.00499
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http://dx.doi.org/10.1152/japplphysiol.00499.2007DOI Listing
December 2007

Thermal responses for men with different fat compositions during immersion in cold water at two depths: prediction versus observation.

Eur J Appl Physiol 2007 May 16;100(1):79-88. Epub 2007 Feb 16.

Biophysics and Biomedical Modeling Division, US Army Research Institute of Environmental Medicine, Kansas St., Natick, MA, 01760, USA.

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http://dx.doi.org/10.1007/s00421-007-0393-zDOI Listing
May 2007

Efficiency of liquid cooling garments: prediction and manikin measurement.

Aviat Space Environ Med 2006 Jun;77(6):644-8

US Army Research Institute of Environmental Medicine, Biophysics and Biomedical Modeling Division, Natick, MA 01760-5007, USA.

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June 2006

[Effects of habitat patch on Lophura nycthemera population].

Ying Yong Sheng Tai Xue Bao 2006 May;17(5):951-3

College of Life Science, Zhejiang University, Hangzhou 310012, China.

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May 2006

Pre-hospital torso-warming modalities for severe hypothermia: a comparative study using a human model.

CJEM 2005 Nov;7(6):378-86

Department of Anesthesia, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.

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November 2005

Thermoregulatory model for prediction of long-term cold exposure.

Comput Biol Med 2005 May;35(4):287-98

Biophysics and Biomedical Modeling Division, US Army Research Institute of Environmental Medicine, Kansas Street, Natick MA01760, USA.

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http://dx.doi.org/10.1016/j.compbiomed.2004.01.004DOI Listing
May 2005

Learning module networks from genome-wide location and expression data.

FEBS Lett 2004 Dec;578(3):297-304

Key Laboratory of Proteomics, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, PR China.

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http://dx.doi.org/10.1016/j.febslet.2004.11.019DOI Listing
December 2004

Model of human thermoregulation for intermittent regional cooling.

Aviat Space Environ Med 2004 Dec;75(12):1065-9

U.S. Army Research Institute of Environmental Medicine, Biophysics and Biomedical Modeling Division, Natick, MA 01760, USA.

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December 2004