Publications

ZnAl-Hydrotalcite-Supported Au25 Nanoclusters as Precatalysts for Chemoselective Hydrogenation of 3-Nitrostyrene.
Angew Chem Int Ed Engl 2017 Mar 31;56(10):2709-2713. Epub 2017 Jan 31.
State Key Laboratory of Catalysis, iChEM, Gold Catalysis Research Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.


Discovery of a Highly Potent, Selective, and Metabolically Stable Inhibitor of Receptor-Interacting Protein 1 (RIP1) for the Treatment of Systemic Inflammatory Response Syndrome.
J Med Chem 2017 Feb 5;60(3):972-986. Epub 2017 Jan 5.
National Institute of Biological Sciences , No. 7 Science Park Road, Zhongguancun Life Science Park, Changping District, Beijing 102206, China.

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.
ChemMedChem 2017 Feb 9;12(3):207-213. Epub 2017 Jan 9.
Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.

Ion-Beam-Directed Self-Ordering of Ga Nanodroplets on GaAs Surfaces.
Nanoscale Res Lett 2016 Dec 27;11(1):38. Epub 2016 Jan 27.
Institute of Fundamental and Frontier Science, State Key Laboratory of Electronic Thin Film and Integrated Devices, University of Electronic Science and Technology of China, Chengdu, 610054, People's Republic of China.


Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors.
ACS Med Chem Lett 2016 Dec 13;7(12):1044-1049. Epub 2016 Sep 13.
Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States; Lineberger Comprehensive Cancer Center, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States; Meryx, Inc., 450 West Dr., Chapel Hill, North Carolina 27599, United States.

Metabolomic profiling of prostate cancer by matrix assisted laser desorption/ionization-Fourier transform ion cyclotron resonance mass spectrometry imaging using Matrix Coating Assisted by an Electric Field (MCAEF).
Biochim Biophys Acta 2016 Dec 23. Epub 2016 Dec 23.
University of Victoria-Genome British Columbia Proteomics Centre, Vancouver Island Technology Park, #3101-4464 Markham St., Victoria, BC V8Z 7X8, Canada; Department of Biochemistry and Microbiology, University of Victoria, Petch Building Room 207, 3800 Finnerty Rd., Victoria, BC V8P 5C2, Canada. Electronic address:

Phase II Study of Hepatic Arterial Infusion Chemotherapy with Oxaliplatin and 5-Fluorouracil for Advanced Perihilar Cholangiocarcinoma.
Radiology 2016 Nov 7:160572. Epub 2016 Nov 7.
From the Department of Interventional Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) (X.W., J.H., G.C., X.Z., R.Y., H.C., H.X., P.L.), Departments of Radiology (Y.C.), Medical Statistics (X.J.), and GI Oncology (Jian Li, Jie Li, L.S.), and Department of Hepatic, Biliary & Pancreatic Surgery (C.H., B.X.), Peking University Cancer Hospital & Institute, 52 Fucheng Road, Haidian District, Beijing 100142, China; and Department of Mathematics and Statistics, University of Minnesota-Duluth, Duluth, Minn (X.L.).

Dynamic expression of corticotropin-releasing hormone and urocortin in estrogen induced-cholestasis pregnant rat.
Reprod Toxicol 2016 Oct 1;65:179-186. Epub 2016 Aug 1.
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu 610041, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, China. Electronic address:

Three-dimensional co-culture of mesenchymal stromal cells and differentiated osteoblasts on human bio-derived bone scaffolds supports active multi-lineage hematopoiesis in vitro: Functional implication of the biomimetic HSC niche.
Int J Mol Med 2016 Oct 19;38(4):1141-51. Epub 2016 Aug 19.
Department of Hematology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan 610072, P.R. China.

Lipiodol retention pattern assessed by cone beam computed tomography during conventional transarterial chemoembolization of hepatocellular carcinoma: accuracy and correlation with response.
Cancer Imaging 2016 Oct 3;16(1):32. Epub 2016 Oct 3.
Department of Interventional Radiology, Peking University Cancer Hospital & Institute, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing, 100142, China.

Minimal Residual Disease Detection and Evolved IGH Clones Analysis in Acute B Lymphoblastic Leukemia Using IGH Deep Sequencing.
Front Immunol 2016 4;7:403. Epub 2016 Oct 4.
BGI-Shenzhen, Shenzhen, China; China National Genebank-Shenzhen, BGI-Shenzhen, Shenzhen, China; Department of Biology, University of Copenhagen, Copenhagen, Denmark.

MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme.
PLoS One 2016 26;11(10):e0165107. Epub 2016 Oct 26.
Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Emory University Department of Pediatrics, Atlanta, GA, 30322, United States of America.



Efficient biallelic mutation in porcine parthenotes using a CRISPR-Cas9 system.
Biochem Biophys Res Commun 2016 Aug 21;476(4):225-9. Epub 2016 May 21.
National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, No. 2 Yuan Ming Yuan Xi Lu, Haidian District, Beijing 100193, PR China. Electronic address:

Resistance to docetaxel in prostate cancer is associated with androgen receptor activation and loss of KDM5D expression.
Proc Natl Acad Sci U S A 2016 May 16;113(22):6259-64. Epub 2016 May 16.
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215; Harvard Medical School, Boston, MA 02215

Designing a Beryllium-Free Deep-Ultraviolet Nonlinear Optical Material without a Structural Instability Problem.
J Am Chem Soc 2016 Mar 25;138(9):2961-4. Epub 2016 Feb 25.
State Key Laboratory of Structural Chemistry, and Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences , Fuzhou, Fujian 350002, China.

Impaired imprinted X chromosome inactivation is responsible for the skewed sex ratio following in vitro fertilization.
Proc Natl Acad Sci U S A 2016 Mar 7;113(12):3197-202. Epub 2016 Mar 7.
National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing 100193, People's Republic of China;

The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia.
JCI Insight 2016 Mar;1(3):e85630
Aflac Cancer Center of Children's Healthcare of Atlanta and Emory University Department of Pediatrics, Atlanta, Georgia, USA. ; Winship Cancer Institute, Emory University, Atlanta, GA, USA.

Antitumor activity of a novel small molecule TLR7 agonist via immune response induction and tumor microenvironment modulation.
Oncol Rep 2016 Feb 18;35(2):793-800. Epub 2015 Nov 18.
Cancer Research Center, National‑Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Medicine, Shenzhen University, Shenzhen, Guangdong 518060, P.R. China.

Strongly enhanced ultraviolet emission of an Au@SiO2/ZnO plasmonic hybrid nanostructure.
Nanoscale 2016 Feb;8(7):4030-6
Institute of Microstructure and Property of Advanced Materials, Beijing University of Technology, Beijing, 100124, P.R. China. and Beijing Key Lab of Microstructure and Property of Advanced Material, Beijing University of Technology, Beijing, 100124, P.R. China.

Genome-Wide Identification of QTL for Seed Yield and Yield-Related Traits and Construction of a High-Density Consensus Map for QTL Comparison in Brassica napus.
Front Plant Sci 2016 28;7:17. Epub 2016 Jan 28.
Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and TechnologyWuhan, China; Hubei Collaborative Innovation Center for the Characteristic Resources Exploitation of Dabie Mountains, Huanggang Normal UniversityHuanggang, China.

Natural Product Kongensin A is a Non-Canonical HSP90 Inhibitor that Blocks RIP3-dependent Necroptosis.
Cell Chem Biol 2016 Feb 28;23(2):257-66. Epub 2016 Jan 28.
National Institute of Biological Sciences, 7 Science Park Road, Zhongguancun Life Science Park, Beijing 102206, China; Collaborative Innovation Center of Systems Biomedicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China. Electronic address:

High-Density SNP Map Construction and QTL Identification for the Apetalous Character in Brassica napus L.
Front Plant Sci 2015 23;6:1164. Epub 2015 Dec 23.
Key Laboratory of Cotton and Rapeseed, Ministry of Agriculture, Institute of Industrial Crops, Jiangsu Academy of Agricultural SciencesNanjing, China; Jiangsu Collaborative Innovation Center for Modern Crop ProductionNanjing, China.

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