Xiaochuan Wang

Xiaochuan Wang

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Xiaochuan Wang

Xiaochuan Wang

Publications by authors named "Xiaochuan Wang"

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64Publications

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Phosphorylation of SET mediates apoptosis via P53 hyperactivation and NM23-H1 nuclear import.

Neurobiol Aging 2018 Sep 8;69:38-47. Epub 2018 May 8.

Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, China. Electronic address:

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September 2018

Vasogenic cerebral edema associated with the disability in activities of daily living in patients with chronic obstructive pulmonary disease.

Brain Behav 2018 Jul 13:e01065. Epub 2018 Jul 13.

Department of Neurology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.

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July 2018

Long-term sequelae of hippocampal lesions in patients with transient global amnesia: A multiparametric MRI study.

J Magn Reson Imaging 2018 May 7;47(5):1350-1358. Epub 2017 Sep 7.

Institute of Brain Diseases and Cognition, Medical College of Xiamen University, Xiamen, P.R. China.

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May 2018

Evaluation of the clinical application of multiple tumor marker protein chip in the diagnostic of lung cancer.

J Clin Lab Anal 2018 May 7:e22565. Epub 2018 May 7.

Department of Oncology, No. 150 Central Hospital of PLA, Luoyang, China.

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May 2018

Late distant recurrence of breast carcinoma and metastasis to the main bronchus and choroid: A case report.

Medicine (Baltimore) 2018 May;97(20):e10754

Cancer Center, The First Affiliated Hospital of Guangzhou University of Chinese Medicine.

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May 2018

A Cohort of 169 Chronic Granulomatous Disease Patients Exposed to BCG Vaccination: a Retrospective Study from a Single Center in Shanghai, China (2004-2017).

J Clin Immunol 2018 Apr 20;38(3):260-272. Epub 2018 Mar 20.

Department of Allergy and Clinical Immunology, Children's Hospital of Fudan University, 399 Wanyuan Road, Shanghai, 201102, China.

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April 2018

BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer's disease.

Proc Natl Acad Sci U S A 2018 04 26;115(15):3954-3959. Epub 2018 Mar 26.

Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, 430030 Wuhan, China;

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April 2018

CK2 Phosphorylating I/SET Mediates Tau Pathology and Cognitive Impairment.

Front Mol Neurosci 2018 30;11:146. Epub 2018 Apr 30.

Key Laboratory of Education Ministry of China for Neurological Disorders, Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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April 2018

Regional cerebral blood flow in natives at high altitude: An arterial spin labeled MRI study.

J Magn Reson Imaging 2018 Mar 1. Epub 2018 Mar 1.

Institute of Brain Diseases and Cognition, Medical College of Xiamen University, Xiamen, China.

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March 2018

Long non-coding RNA CASC2 inhibits tumorigenesis via the miR-181a/PLXNC1 axis in melanoma.

Acta Biochim Biophys Sin (Shanghai) 2018 Mar;50(3):263-272

Department of Dermatology, The First People's Hospital of Yunnan Province, Kunming 650032, China.

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March 2018

Ginkgo biloba Extract EGb761 Attenuates Hyperhomocysteinemia-induced AD Like Tau Hyperphosphorylation and Cognitive Impairment in Rats.

Curr Alzheimer Res 2018 ;15(1):89-99

Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030. China.

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January 2018

7,8-Dihydroxyflavone ameliorates high-glucose induced diabetic apoptosis in human retinal pigment epithelial cells by activating TrkB.

Biochem Biophys Res Commun 2018 01 3;495(1):922-927. Epub 2017 Nov 3.

Department of Ophthalmology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510405, China.

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January 2018

Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments.

J Alzheimers Dis 2018 ;63(3):1141-1159

Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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January 2018

AKT2 deficiency induces retardation of myocyte development through EndoG-MEF2A signaling in mouse heart.

Biochem Biophys Res Commun 2017 12 28;493(4):1410-1417. Epub 2017 Sep 28.

State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China. Electronic address:

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December 2017

Interleukin-6 deficiency attenuates angiotensin II-induced cardiac pathogenesis with increased myocyte hypertrophy.

Biochem Biophys Res Commun 2017 12 25;494(3-4):534-541. Epub 2017 Oct 25.

State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China. Electronic address:

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December 2017

Interactions between poly-(phthalazinone ether sulfone ketone) (PPESK) and TNT or TATB in polymer bonded explosives: a molecular dynamic simulation study.

J Mol Model 2017 Nov 7;23(12):334. Epub 2017 Nov 7.

School of Chemistry and Chemical Technology, Beijing Institute of Technology, Beijing, China.

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November 2017

The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD.

BMC Med Genet 2017 11 13;18(1):127. Epub 2017 Nov 13.

Department of Clinical Immunology, Children's Hospital of Fudan University, 399 Wanyuan Road, Shanghai, 201102, China.

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November 2017

Sex Differences in the Cognitive and Hippocampal Effects of Streptozotocin in an Animal Model of Sporadic AD.

Front Aging Neurosci 2017 31;9:347. Epub 2017 Oct 31.

Key Laboratory of Ministry of Education of China for Neurological Disorders, Department of Pathophysiology, School of Basic Medicine and the Collaborative Innovation Center for Brain Science, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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October 2017

Experimental Investigation on Surface Quality Processed by Self-Excited Oscillation Pulsed Waterjet Peening.

Materials (Basel) 2017 Aug 25;10(9). Epub 2017 Aug 25.

Key Laboratory of Hydraulic Machinery Transients, Ministry of Education, Wuhan University, Wuhan 430072, China.

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August 2017

GSK-3β deletion in dentate gyrus excitatory neuron impairs synaptic plasticity and memory.

Sci Rep 2017 Jul 18;7(1):5781. Epub 2017 Jul 18.

Department of Pathophysiology, School of Basic Medicine and the Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, PR China.

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July 2017

Expression of P301L-hTau in mouse MEC induces hippocampus-dependent memory deficit.

Sci Rep 2017 Jun 20;7(1):3914. Epub 2017 Jun 20.

Department of Pathophysiology, School of Basic Medicine and the Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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June 2017

5-Aminolaevulinic Acid-Based Photodynamic Therapy Restrains Pathological Hyperplasia of Fibroblasts.

Med Sci Monit 2017 Jan 4;23:46-56. Epub 2017 Jan 4.

Department of Dermatology, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China (mainland).

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January 2017

Asperterpenes A and B, two unprecedented meroterpenoids from with BACE1 inhibitory activities.

Chem Sci 2016 Oct 27;7(10):6563-6572. Epub 2016 Jun 27.

Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation , School of Pharmacy , Tongji Medical College , Huazhong University of Science and Technology , Wuhan 430030 , China . Email:

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October 2016

Memantine Attenuates Alzheimer's Disease-Like Pathology and Cognitive Impairment.

PLoS One 2015 23;10(12):e0145441. Epub 2015 Dec 23.

Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, United States of America.

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August 2016

Reactive oxygen species generated from skeletal muscles are required for gecko tail regeneration.

Sci Rep 2016 Feb 8;6:20752. Epub 2016 Feb 8.

Key Laboratory of Neuroregeneration, Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226001, PR China.

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February 2016

Inhibition of Protein Phosphatase-2A (PP2A) by I1PP2A Leads to Hyperphosphorylation of Tau, Neurodegeneration, and Cognitive Impairment in Rats.

J Alzheimers Dis 2015 ;45(2):423-35

Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.

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January 2016

Efficacy of allergen-specific immunotherapy for peanut allergy: a meta-analysis of randomized controlled trials.

Allergy Asthma Proc 2014 Mar-Apr;35(2):171-7

Department of Clinical Immunology, Children's Hospital of Fudan University, Shanghai, China.

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December 2014

Clinical characteristics and immunogenetics of BCGosis/BCGitis in Chinese children: a 6 year follow-up study.

PLoS One 2014 10;9(4):e94485. Epub 2014 Apr 10.

Department of Clinical Immunology, Children's Hospital of Fudan University, Shanghai, China.

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December 2014

Heterozygous splice mutation in PIK3R1 causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K.

J Exp Med 2014 Dec 8;211(13):2537-47. Epub 2014 Dec 8.

Molecular Development of the Immune System Section, Laboratory of Immunology; NIAID Clinical Genomics Program; Human Immunological Diseases Unit, Laboratory of Host Defenses; and Intramural Clinical Management and Operations Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 Molecular Development of the Immune System Section, Laboratory of Immunology; NIAID Clinical Genomics Program; Human Immunological Diseases Unit, Laboratory of Host Defenses; and Intramural Clinical Management and Operations Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892

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December 2014

Animal models of the sporadic form of Alzheimer's disease: focus on the disease and not just the lesions.

J Alzheimers Dis 2013 ;37(3):469-74

Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.

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June 2014

Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection.

Acta Neuropathol 2014 Feb 18;127(2):243-56. Epub 2013 Oct 18.

Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research, In Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY, 10314-6399, USA.

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February 2014

Ser9 phosphorylation causes cytoplasmic detention of I2PP2A/SET in Alzheimer disease.

Neurobiol Aging 2013 Jul 29;34(7):1748-58. Epub 2013 Jan 29.

Department of Pathophysiology, Key Laboratory of Neurological Disease of National Education Ministry, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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July 2013

Cleavage of GSK-3β by calpain counteracts the inhibitory effect of Ser9 phosphorylation on GSK-3β activity induced by H₂O₂.

J Neurochem 2013 Jul 30;126(2):234-42. Epub 2013 May 30.

Department of Pathophysiology, Key Laboratory of Neurological Disease of National Education Ministry, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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July 2013

Antioxidant therapies for Alzheimer's disease.

Oxid Med Cell Longev 2012 25;2012:472932. Epub 2012 Jul 25.

Department of Pathophysiology, Key Laboratory of Neurological Disease of National Education Ministry, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

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November 2012

Grey and white matter abnormalities in chronic obstructive pulmonary disease: a case-control study.

BMJ Open 2012 24;2(2):e000844. Epub 2012 Apr 24.

Department of Physiology, Medical College of Xiamen University, Xiamen, China.

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October 2012

Compromised white matter microstructural integrity after mountain climbing: evidence from diffusion tensor imaging.

High Alt Med Biol 2012 Jun;13(2):118-25

Department of Physiology and Neurobiology, Medical College of Xiamen University, Xiamen, China.

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June 2012

An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide.

Acta Neuropathol 2012 Jan 15;123(1):133-51. Epub 2011 Nov 15.

Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA.

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January 2012

Berberine attenuates calyculin A-induced cytotoxicity and Tau hyperphosphorylation in HEK293 cells.

J Alzheimers Dis 2011 ;24(3):525-35

Department of Pathophysiology, Key Laboratory of Neurological Disease of National Education Ministry, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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September 2011

The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment.

FASEB J 2010 Nov 22;24(11):4420-32. Epub 2010 Jul 22.

Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY 10314, USA.

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November 2010

Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries.

Authors:
Ludovic de Beaucoudrey Arina Samarina Jacinta Bustamante Aurélie Cobat Stéphanie Boisson-Dupuis Jacqueline Feinberg Saleh Al-Muhsen Lucile Jannière Yoann Rose Maylis de Suremain Xiao-Fei Kong Orchidée Filipe-Santos Ariane Chapgier Capucine Picard Alain Fischer Figen Dogu Aydan Ikinciogullari Gonul Tanir Sami Al-Hajjar Suliman Al-Jumaah Husn H Frayha Zobaida AlSum Sulaiman Al-Ajaji Abdullah Alangari Abdulaziz Al-Ghonaium Parisa Adimi Davood Mansouri Imen Ben-Mustapha Judith Yancoski Ben-Zion Garty Carlos Rodriguez-Gallego Isabel Caragol Necil Kutukculer Dinakantha S Kumararatne Smita Patel Rainer Doffinger Andrew Exley Olle Jeppsson Janine Reichenbach David Nadal Yaryna Boyko Barbara Pietrucha Suzanne Anderson Michael Levin Liliane Schandené Kinda Schepers André Efira Françoise Mascart Masao Matsuoka Tatsunori Sakai Claire-Anne Siegrist Klara Frecerova Renate Blüetters-Sawatzki Jutta Bernhöft Joachim Freihorst Ulrich Baumann Darko Richter Filomeen Haerynck Frans De Baets Vas Novelli David Lammas Christiane Vermylen David Tuerlinckx Chris Nieuwhof Malgorzata Pac Walther H Haas Ingrid Müller-Fleckenstein Bernhard Fleckenstein Jacob Levy Revathi Raj Aileen Cleary Cohen David B Lewis Steven M Holland Kuender D Yang Xiaochuan Wang Xiaohong Wang Liping Jiang Xiqiang Yang Chaomin Zhu Yuanyuan Xie Pamela Pui Wah Lee Koon Wing Chan Tong-Xin Chen Gabriela Castro Ivelisse Natera Ana Codoceo Alejandra King Liliana Bezrodnik Daniela Di Giovani Maria Isabel Gaillard Dewton de Moraes-Vasconcelos Anete Sevciovic Grumach Alberto Jose da Silva Duarte Ruth Aldana Francisco Javier Espinosa-Rosales Mohammed Bejaoui Ahmed Aziz Bousfiha Jamila El Baghdadi Namik Ozbek Guzide Aksu Melike Keser Ayper Somer Nevin Hatipoglu Cigdem Aydogmus Suna Asilsoy Yildiz Camcioglu Saniye Gülle Tuba T Ozgur Meteran Ozen Matias Oleastro Andrea Bernasconi Setareh Mamishi Nima Parvaneh Sergio Rosenzweig Ridha Barbouche Sigifredo Pedraza Yu Lung Lau Mohammad S Ehlayel Claire Fieschi Laurent Abel Ozden Sanal Jean-Laurent Casanova

Medicine (Baltimore) 2010 Nov;89(6):381-402

Laboratory of Human Genetics of Infectious Diseases U980, Institut National de la Santé et de la Recherche Médicale, Paris, France.

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November 2010

Alzheimer's disease neurofibrillary degeneration: pivotal and multifactorial.

Biochem Soc Trans 2010 Aug;38(4):962-6

Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, New York, NY 10314, USA.

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August 2010

Investigation of selective molecular interactions using two-dimensional Fourier transform IR spectroscopy.

Anal Bioanal Chem 2010 May 19;397(1):339-343. Epub 2010 Jan 19.

State Key Lab of Polymer Materials Engineering, Polymer Research Institute, Sichuan University, Chengdu, 610065, Sichuan, China.

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May 2010

Mutation of the BTK gene and clinical feature of X-linked agammaglobulinemia in mainland China.

J Clin Immunol 2009 May 28;29(3):352-6. Epub 2008 Nov 28.

Department of Clinical Immunology, Jeffrey Modell Diagnostic and Research Center, Children's Hospital of Fudan University, 399 Wanyuan Road, Shanghai 201102, China.

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May 2009

Pi-stacked interactions in explosive crystals: buffers against external mechanical stimuli.

J Am Chem Soc 2008 Jul 5;130(26):8359-65. Epub 2008 Jun 5.

Laboratory of Material Chemistry, Institute of Chemical Materials, China Academy of Engineering Physics, P.O. Box 919-327, Mianyang, Sichuan, PR China 621900.

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July 2008

[Experimental study on role of endotoxin in induction of murine model of allergic asthma].

Wei Sheng Yan Jiu 2008 Jul;37(4):397-404

School of Public Health, Fudan University, Shanghai 200032, China.

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July 2008

Cytotoxic withanolides from the flowers of Datura metel.

J Nat Prod 2007 Jul 21;70(7):1127-32. Epub 2007 Jun 21.

State Key Laboratory of Virology, College of Pharmacy, Wuhan University, Wuhan 430072, People's Republic of China.

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July 2007

Retinoic acid enhances the production of IL-10 while reducing the synthesis of IL-12 and TNF-alpha from LPS-stimulated monocytes/macrophages.

J Clin Immunol 2007 Mar 26;27(2):193-200. Epub 2007 Jan 26.

Children's Hospital, Medical Center of Fudan University, Shanghai, P.R. China.

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March 2007

Indirect laser-induced fluorescence detection of diuretics separated by capillary electrophoresis.

J Sep Sci 2006 Mar;29(5):677-83

Department of Chemistry, Fudan University, Shanghai, China.

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March 2006

A screening library for peptide activated G-protein coupled receptors. 1. The test set.

J Med Chem 2004 Dec;47(27):6864-74

Chemistry Department, Neurocrine Biosciences, 12790 El Camino Real, San Diego, CA 92130, USA.

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December 2004

Expression and regulation of nuclear retinoic acid receptors in human lymphoid cells.

J Clin Immunol 2003 Jan;23(1):46-54

Division of Allergy/Immunology and Pediatric Rheumatology, Department of Pediatrics, Children's Hospital of Buffalo, SUNY Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14222, USA.

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January 2003

Levels of nonphosphorylated and phosphorylated tau in cerebrospinal fluid of Alzheimer's disease patients : an ultrasensitive bienzyme-substrate-recycle enzyme-linked immunosorbent assay.

Am J Pathol 2002 Apr;160(4):1269-78

Pathophysiology Department, Institute forNeuroscience, Tongji Medical School, Huazhong University of Science andTechnology, Wuhan, People's Republic of China.

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April 2002

In vitro analysis of tau phosphorylation sites and its biological activity.

Chin Med Sci J 2002 Mar;17(1):13-6

Tongji Medical College, Hua Zhong University of Science and Technology, Wuhan 430030.

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March 2002