Xiaochen Gu

Xiaochen Gu

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Xiaochen Gu

Xiaochen Gu

Publications by authors named "Xiaochen Gu"

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Glucose-responsive mesoporous silica nanoparticles to generation of hydrogen peroxide for synergistic cancer starvation and chemistry therapy.

Int J Nanomedicine 2019 2;14:2233-2251. Epub 2019 Apr 2.

Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, , People's Republic of China.

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https://www.dovepress.com/glucose-responsive-mesoporous-sili
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http://dx.doi.org/10.2147/IJN.S195900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498395PMC
July 2019

Hyaluronic acid-functionalized half-generation of sectorial dendrimers for anticancer drug delivery and enhanced biocompatibility.

Carbohydr Polym 2018 Dec 9;202:513-522. Epub 2018 Sep 9.

Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01448617183107
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http://dx.doi.org/10.1016/j.carbpol.2018.09.015DOI Listing
December 2018

Reduction-sensitive mixed micelles for selective intracellular drug delivery to tumor cells and reversal of multidrug resistance.

Int J Pharm 2018 Oct 13;550(1-2):1-13. Epub 2018 Aug 13.

Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2018.08.019DOI Listing
October 2018

Bio-inspired drug delivery systems: an emerging platform for targeted cancer therapy.

Biomater Sci 2018 May;6(5):958-973

State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China.

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http://xlink.rsc.org/?DOI=C8BM00175H
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http://dx.doi.org/10.1039/C8BM00175HDOI Listing
May 2018

Nanostructured Peptidotoxins as Natural Pro-Oxidants Induced Cancer Cell Death via Amplification of Oxidative Stress.

ACS Appl Mater Interfaces 2018 Feb 27;10(5):4569-4581. Epub 2018 Jan 27.

State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University , Nanjing 210009, China.

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http://dx.doi.org/10.1021/acsami.7b18809DOI Listing
February 2018

Simultaneous quantification of reparixin and paclitaxel in plasma and urine using ultra performance liquid chromatography-tandem mass spectroscopy (UHPLC-MS/MS): Application to a preclinical pharmacokinetic study in rats.

J Chromatogr B Analyt Technol Biomed Life Sci 2017 Mar 3;1046:165-171. Epub 2017 Feb 3.

College of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, R3E 0T5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2016.12.015DOI Listing
March 2017

Green design "bioinspired disassembly-reassembly strategy" applied for improved tumor-targeted anticancer drug delivery.

J Control Release 2016 08 27;235:134-146. Epub 2016 May 27.

State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2016.05.055DOI Listing
August 2016

Sorption characteristics of phenanthrene and pyrene to surfactant-modified peat from aqueous solution: the contribution of partition and adsorption.

Water Sci Technol 2015 ;71(2):296-302

Key Laboratory of Coal Gasification and Energy Chemical Engineering of Ministry of Education, East China University of Science and Technology, No. 130, Meilong Road, Shanghai 200237, China E-mail:

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https://iwaponline.com/wst/article/71/2/296/18813/Sorption-c
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http://dx.doi.org/10.2166/wst.2014.517DOI Listing
October 2015

Intracellular delivery and antitumor effects of a redox-responsive polymeric paclitaxel conjugate based on hyaluronic acid.

Acta Biomater 2015 Oct 20;26:274-85. Epub 2015 Aug 20.

Department of Pharmaceutics, China Pharmaceutical University, Nanjing 210009, China. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2015.08.029DOI Listing
October 2015

Nanocarrier-mediated drugs targeting cancer stem cells: an emerging delivery approach.

Expert Opin Drug Deliv 2015 Jul 20;12(7):1177-201. Epub 2015 Jan 20.

University of Manitoba, College of Pharmacy, Faculty of Health Sciences , 750 McDermot Avenue Winnipeg, MB R3E 0H5 , Canada.

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http://www.tandfonline.com/doi/full/10.1517/17425247.2015.99
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http://dx.doi.org/10.1517/17425247.2015.998648DOI Listing
July 2015

Preparation of Hollow N-Chloramine-Functionalized Hemispherical Silica Particles with Enhanced Efficacy against Bacteria in the Presence of Organic Load: Synthesis, Characterization, and Antibacterial Activity.

ACS Appl Mater Interfaces 2015 Jun 21;7(21):11536-46. Epub 2015 May 21.

§College of Pharmacy, University of Manitoba, Winnipeg, Manitoba R3E 0T5, Canada.

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http://dx.doi.org/10.1021/acsami.5b02486DOI Listing
June 2015

Kidney-specific drug delivery system for renal fibrosis based on coordination-driven assembly of catechol-derived chitosan.

Biomaterials 2014 Aug 23;35(25):7157-71. Epub 2014 May 23.

Department of Pharmaceutics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612140051
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http://dx.doi.org/10.1016/j.biomaterials.2014.04.106DOI Listing
August 2014

Direct cytosolic siRNA delivery by reconstituted high density lipoprotein for target-specific therapy of tumor angiogenesis.

Biomaterials 2014 Aug 27;35(25):7214-27. Epub 2014 May 27.

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.

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http://dx.doi.org/10.1016/j.biomaterials.2014.05.009DOI Listing
August 2014

Evaluation of percutaneous permeation of repellent DEET and sunscreen oxybenzone from emulsion-based formulations in artificial membrane and human skin.

Acta Pharm Sin B 2014 Feb 13;4(1):43-51. Epub 2014 Jan 13.

Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba R3E 0T5, Canada.

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http://dx.doi.org/10.1016/j.apsb.2013.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590294PMC
February 2014

pH-dependent stability of creatine ethyl ester: relevance to oral absorption.

J Diet Suppl 2013 Sep;10(3):241-51

College of Pharmacy University of Nebraska Medical Center, Nebraska Medical Center, Omaha, Nebraska 68198-6025, USA.

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http://dx.doi.org/10.3109/19390211.2013.822453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469200PMC
September 2013

Synthesis and characterization of multi-functional linear-dendritic block copolymer for intracellular delivery of antitumor drugs.

Int J Pharm 2013 Aug 13;452(1-2):363-73. Epub 2013 May 13.

Department of Pharmaceutics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.

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http://dx.doi.org/10.1016/j.ijpharm.2013.05.003DOI Listing
August 2013

Metabolic disposition of the insect repellent DEET and the sunscreen oxybenzone following intravenous and skin administration in rats.

Int J Toxicol 2012 Sep-Oct;31(5):467-76

Faculty of Pharmacy, University of Manitoba, 750 McDermot Avenue, Winnipeg, MB R3E 0T5, Canada.

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http://dx.doi.org/10.1177/1091581812459893DOI Listing
March 2013

Tissue disposition of the insect repellent DEET and the sunscreen oxybenzone following intravenous and topical administration in rats.

Biopharm Drug Dispos 2011 Oct 2;32(7):369-79. Epub 2011 Aug 2.

Faculty of Pharmacy, University of Manitoba, Winnipeg, MB R3E0T5, Canada.

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http://dx.doi.org/10.1002/bdd.765DOI Listing
October 2011

Tissue deposition of the insect repellent DEET and the sunscreen oxybenzone from repeated topical skin applications in rats.

Int J Toxicol 2010 Dec 19;29(6):594-603. Epub 2010 Oct 19.

Faculty of Pharmacy, University of Manitoba, 750 McDermot Avenue, Winnipeg, MB R3E 0T5, Canada.

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http://journals.sagepub.com/doi/10.1177/1091581810380147
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http://dx.doi.org/10.1177/1091581810380147DOI Listing
December 2010

In vitro permeation characterization of repellent picaridin and sunscreen oxybenzone.

Pharm Dev Technol 2009 ;14(3):332-40

Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada.

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http://dx.doi.org/10.1080/10837450802647318DOI Listing
October 2010

Physicochemical characterization of creatine N-methylguanidinium salts.

J Diet Suppl 2010 Sep;7(3):240-52

Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, Nebraska, USA.

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http://dx.doi.org/10.3109/19390211.2010.491507DOI Listing
September 2010

Effect of drug solubility on polymer hydration and drug dissolution from polyethylene oxide (PEO) matrix tablets.

AAPS PharmSciTech 2008 8;9(2):437-43. Epub 2008 Mar 8.

Faculty of Pharmacy, University of Manitoba, 50 Sifton Road, Winnipeg, MB R3T2N2, Canada.

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http://dx.doi.org/10.1208/s12249-008-9060-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976924PMC
September 2008

In vitro permeation characterization of the analgesic ibuprofen and the sunscreen oxybenzone.

Drug Dev Ind Pharm 2008 Aug;34(8):845-52

Faculty of Pharmacy, University of Manitoba, Winnipeg, MB, Canada.

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http://dx.doi.org/10.1080/03639040801928697 DOI Listing
August 2008

Axotomy-induced up-regulation of tumor necrosis factor-alpha in the dorsal root ganglia.

Neurol Res 2008 Jul 16;30(6):623-31. Epub 2008 May 16.

Faculty of Pharmacy, University of Manitoba, Winnipeg, Man., Canada.

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http://dx.doi.org/10.1179/174313208X289606DOI Listing
July 2008

Correlation between drug dissolution and polymer hydration: a study using texture analysis.

Int J Pharm 2007 Sep 5;342(1-2):18-25. Epub 2007 May 5.

Faculty of Pharmacy, University of Manitoba, 50 Sifton Road, Winnipeg, Manitoba, Canada R3T 2N2.

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http://dx.doi.org/10.1016/j.ijpharm.2007.04.024DOI Listing
September 2007

Percutaneous characterization of the insect repellent DEET and the sunscreen oxybenzone from topical skin application.

Toxicol Appl Pharmacol 2007 Sep 4;223(2):187-94. Epub 2007 Jun 4.

Faculty of Pharmacy, Department of Animal Science, University of Manitoba, 50 Sifton Road, Winnipeg, MB, Canada R3T 2N2.

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http://dx.doi.org/10.1016/j.taap.2007.05.016DOI Listing
September 2007

In vitro percutaneous permeation of the repellent DEET and the sunscreen oxybenzone across human skin.

J Pharm Pharm Sci 2007 ;10(1):17-25

Faculty of Pharmacy, University of Manitoba, Winnipeg, MB, Canada R3T 2N2.

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https://www.ualberta.ca/~csps/JPPS10_1/MS_1112/MS_1112_Forma
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May 2007

Quantification of antihistamine acrivastine in plasma by solid-phase extraction and high-performance liquid chromatography.

J Pharm Biomed Anal 2007 Jan 22;43(1):293-7. Epub 2006 Aug 22.

Faculty of Pharmacy, University of Manitoba, 50 Sifton Road, Winnipeg, Man., Canada R3T 2N2.

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http://dx.doi.org/10.1016/j.jpba.2006.07.009DOI Listing
January 2007

In vitro permeation of repellent DEET and sunscreen oxybenzone across three artificial membranes.

Int J Pharm 2006 Mar 18;310(1-2):110-7. Epub 2006 Jan 18.

Faculty of Pharmacy, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.

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http://dx.doi.org/10.1016/j.ijpharm.2005.11.039DOI Listing
March 2006

Simultaneous analysis of insect repellent DEET, sunscreen oxybenzone and five relevant metabolites by reversed-phase HPLC with UV detection: application to an in vivo study in a piglet model.

J Chromatogr B Analyt Technol Biomed Life Sci 2005 Aug;822(1-2):271-7

Faculty of Pharmacy, University of Manitoba, 50 Sifton Road, Winnipeg, Man., Canada.

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http://dx.doi.org/10.1016/j.jchromb.2005.06.015DOI Listing
August 2005

Evaluation and comparison of five matrix excipients for the controlled release of acrivastine and pseudoephedrine.

Drug Dev Ind Pharm 2004 ;30(10):1009-17

Faculty of Pharmacy, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.

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http://dx.doi.org/10.1081/ddc-200040237DOI Listing
April 2005

Simultaneous analysis of the H1-antihistamine acrivastine and the decongestant pseudoephedrine hydrochloride by high-performance liquid chromatography.

J Pharm Biomed Anal 2005 Apr 25;37(4):663-7. Epub 2004 Dec 25.

Faculty of Pharmacy, University of Manitoba, 50 Sifton Road, Winnipeg, Manitoba, Canada R3T 2N2.

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http://dx.doi.org/10.1016/j.jpba.2004.10.054DOI Listing
April 2005

Hydroxyzine- and cetirizine-loaded liposomes: effect of duration of thin film hydration, freeze-thawing, and changing buffer pH on encapsulation and stability.

Drug Dev Ind Pharm 2005 Mar;31(3):281-91

Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada.

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http://dx.doi.org/10.1081/ddc-52070DOI Listing
March 2005

Cetirizine from topical phosphatidylcholine liposomes: evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model.

Biopharm Drug Dispos 2004 Nov;25(8):359-66

Faculty of Pharmacy, University of Manitoba, Winnipeg, Canada.

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http://dx.doi.org/10.1002/bdd.419DOI Listing
November 2004

In-vitro permeation of the insect repellent N,N-diethyl-m-toluamide (DEET) and the sunscreen oxybenzone.

J Pharm Pharmacol 2004 May;56(5):621-8

Faculty of Pharmacy, University of Manitoba, 50 Sifton Road, Winnipeg, Manitoba, Canada R3T 2N2.

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http://dx.doi.org/10.1211/0022357023402DOI Listing
May 2004

Clinical pharmacology of H1-antihistamines in the skin.

J Allergy Clin Immunol 2002 Nov;110(5):777-83

Department of Pediatrics & Child Health, Faculty of Medicine, University of Manitoba, Canada.

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http://dx.doi.org/10.1067/mai.2002.129123DOI Listing
November 2002

Is epinephrine administration by sublingual tablet feasible for the first-aid treatment of anaphylaxis? A proof-of-concept study.

Biopharm Drug Dispos 2002 Jul;23(5):213-6

Assistant Professor, Division of Pharmaceutical Sciences, Faculty of Pharmacy, University of Manitoba, Canada R3T 2N2.

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http://doi.wiley.com/10.1002/bdd.312
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http://dx.doi.org/10.1002/bdd.312DOI Listing
July 2002

EpiPen Jr versus EpiPen in young children weighing 15 to 30 kg at risk for anaphylaxis.

J Allergy Clin Immunol 2002 Jan;109(1):171-5

Department of Pediatrics & Child Health, Faculty of Medicine, University of Manitoba, Canada.

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http://dx.doi.org/10.1067/mai.2002.120758DOI Listing
January 2002