Xiao-Feng Le

Xiao-Feng Le

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Xiao-Feng Le

Xiao-Feng Le

Publications by authors named "Xiao-Feng Le"

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35Publications

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Comparison of the One-Time Accuracy of Simulated Freehand and Navigation Simulated Pedicle Screw Insertion.

World Neurosurg 2019 Apr 25. Epub 2019 Apr 25.

Department of Spine Surgery, Beijing Jishuitan Hospital and Peking University Fourth School of Clinical Medicine, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2019.04.151DOI Listing
April 2019

Jab1/Csn5-Thioredoxin Signaling in Relapsed Acute Monocytic Leukemia under Oxidative Stress.

Clin Cancer Res 2017 Aug 7;23(15):4450-4461. Epub 2017 Mar 7.

Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861712PMC
August 2017

Clinically relevant microRNAs in ovarian cancer.

Mol Cancer Res 2015 Mar 10;13(3):393-401. Epub 2014 Oct 10.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369176PMC
March 2015

ATP directed agent, 8-chloro-adenosine, induces AMP activated protein kinase activity, leading to autophagic cell death in breast cancer cells.

J Hematol Oncol 2014 Mar 14;7:23. Epub 2014 Mar 14.

Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Unit 1950, P,O, Box 301429, Houston, TX 77230-1429, USA.

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http://dx.doi.org/10.1186/1756-8722-7-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007639PMC
March 2014

Preferential inhibition of hepatocellular carcinoma by the flavonoid Baicalein through blocking MEK-ERK signaling.

Int J Oncol 2012 Sep 6;41(3):969-78. Epub 2012 Jun 6.

Department of General Surgery, Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710004, P.R. China.

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http://dx.doi.org/10.3892/ijo.2012.1510DOI Listing
September 2012

iASPP and chemoresistance in ovarian cancers: effects on paclitaxel-mediated mitotic catastrophe.

Clin Cancer Res 2011 Nov 16;17(21):6924-33. Epub 2011 Sep 16.

Department of Pathology, The University of Hong Kong, Hong Kong Special Administrative Region, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-0588DOI Listing
November 2011

A genistein derivative, ITB-301, induces microtubule depolymerization and mitotic arrest in multidrug-resistant ovarian cancer.

Cancer Chemother Pharmacol 2011 Oct 22;68(4):1033-44. Epub 2011 Feb 22.

Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Unit 422, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s00280-011-1575-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180612PMC
October 2011

Modulating microtubule stability enhances the cytotoxic response of cancer cells to Paclitaxel.

Cancer Res 2011 Sep 20;71(17):5806-17. Epub 2011 Jul 20.

Department of Experimental Therapeutics, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-0025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679477PMC
September 2011

The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.

J Natl Cancer Inst 2011 Sep 2;103(18):1403-22. Epub 2011 Aug 2.

Department of Experimental Therapeutics, the University of Texas M. D. Anderson Cancer Center, Unit 354, Rm Y6.5343, 1515 Holcombe Blvd, Houston, TX, USA.

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http://dx.doi.org/10.1093/jnci/djr280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176777PMC
September 2011

Src family kinases and paclitaxel sensitivity.

Cancer Biol Ther 2011 Aug 15;12(4):260-9. Epub 2011 Aug 15.

Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173729PMC
http://dx.doi.org/10.4161/cbt.12.4.16430DOI Listing
August 2011

Stat3 and CCAAT/enhancer binding protein beta (C/EBP-beta) regulate Jab1/CSN5 expression in mammary carcinoma cells.

Breast Cancer Res 2011 Jun 20;13(3):R65. Epub 2011 Jun 20.

Department of Systems Biology, University of Texas - MD Anderson Cancer Center, Houston, 77030, USA.

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http://dx.doi.org/10.1186/bcr2902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218954PMC
June 2011

A novel compound modified from tanshinone inhibits tumor growth in vivo via activation of the intrinsic apoptotic pathway.

Cancer Lett 2010 Nov 21;297(1):18-30. Epub 2010 May 21.

Department of Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.

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http://dx.doi.org/10.1016/j.canlet.2010.04.020DOI Listing
November 2010

Dasatinib induces autophagic cell death in human ovarian cancer.

Cancer 2010 Nov;116(21):4980-90

Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4009, USA.

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http://dx.doi.org/10.1002/cncr.25426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975555PMC
November 2010

MEKK3 expression correlates with nuclear factor kappa B activity and with expression of antiapoptotic genes in serous ovarian carcinoma.

Cancer 2009 Sep;115(17):3897-908

Department of Biochemistry and Molecular Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1002/cncr.24445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061353PMC
September 2009

[Challenges and expectations for early diagnosis of lung cancer].

Zhonghua Yi Xue Za Zhi 2009 Jun;89(24):1659-61

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June 2009

Specific blockade of VEGF and HER2 pathways results in greater growth inhibition of breast cancer xenografts that overexpress HER2.

Cell Cycle 2008 Dec 16;7(23):3747-58. Epub 2008 Dec 16.

Department of Experimental Therapeutics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757147PMC
http://dx.doi.org/10.4161/cc.7.23.7212DOI Listing
December 2008

Role of PELP1/MNAR signaling in ovarian tumorigenesis.

Cancer Res 2008 Jun;68(12):4902-9

Department of Obstetrics and Gynecology and Cancer Research and Therapy Center at The University of Texas Health Science Center, San Antonio, Texas, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-5698DOI Listing
June 2008

Roles of human epidermal growth factor receptor 2, c-jun NH2-terminal kinase, phosphoinositide 3-kinase, and p70 S6 kinase pathways in regulation of cyclin G2 expression in human breast cancer cells.

Mol Cancer Ther 2007 Nov;6(11):2843-57

Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-0109DOI Listing
November 2007

Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway.

Cell Cycle 2006 Aug 1;5(15):1654-61. Epub 2006 Aug 1.

Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas 77030-4009, USA.

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http://dx.doi.org/10.4161/cc.5.15.3007DOI Listing
August 2006

Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling.

J Biol Chem 2005 Jan 25;280(3):2092-104. Epub 2004 Oct 25.

Department of Experimental Therapeutics, the University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M403080200
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http://dx.doi.org/10.1074/jbc.M403080200DOI Listing
January 2005

HER2-targeting antibodies modulate the cyclin-dependent kinase inhibitor p27Kip1 via multiple signaling pathways.

Cell Cycle 2005 Jan 10;4(1):87-95. Epub 2005 Jan 10.

Department of Experimental Therapeutics, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.4161/cc.4.1.1360DOI Listing
January 2005

The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition.

J Biol Chem 2003 Jun 16;278(26):23441-50. Epub 2003 Apr 16.

Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1074/jbc.M300848200DOI Listing
June 2003

Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis.

Oncogene 2003 Jan;22(4):484-97

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston 77030, USA.

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http://dx.doi.org/10.1038/sj.onc.1206175DOI Listing
January 2003

Reexpression of the tumor suppressor gene ARHI induces apoptosis in ovarian and breast cancer cells through a caspase-independent calpain-dependent pathway.

Cancer Res 2002 Dec;62(24):7264-72

Department of Experimental Therapeutics, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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December 2002