Xianlin Han

Xianlin Han

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Xianlin Han

Publications by authors named "Xianlin Han"

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Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors.

J Enzyme Inhib Med Chem 2019 Dec;34(1):150-162

a Hubei Province Key Laboratory of Occupational Hazard Identification and Control , Wuhan University of Science and Technology , Wuhan , China.

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https://www.tandfonline.com/doi/full/10.1080/14756366.2018.1
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http://dx.doi.org/10.1080/14756366.2018.1530224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237161PMC
December 2019

Tutorial on lipidomics.

Anal Chim Acta 2019 Jul 1;1061:28-41. Epub 2019 Feb 1.

Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA; Department of Medicine - Diabetes, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2019.01.043DOI Listing
July 2019

Strategies to Improve/Eliminate the Limitations in Shotgun Lipidomics.

Proteomics 2019 Jul 10:e1900070. Epub 2019 Jul 10.

Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.

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http://dx.doi.org/10.1002/pmic.201900070DOI Listing
July 2019

Early detection of cognitive impairment in patients with insulinoma.

Endocrine 2019 Jul 10. Epub 2019 Jul 10.

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1007/s12020-019-01994-xDOI Listing
July 2019

Publisher Correction: Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration.

Nat Immunol 2019 Jun;20(6):765-767

Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

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http://dx.doi.org/10.1038/s41590-019-0401-6DOI Listing
June 2019

Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration.

Nat Immunol 2019 05 1;20(5):626-636. Epub 2019 Apr 1.

Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

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http://dx.doi.org/10.1038/s41590-019-0356-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537107PMC
May 2019

Defective Phosphatidylglycerol Remodeling Causes Hepatopathy, Linking Mitochondrial Dysfunction to Hepatosteatosis.

Cell Mol Gastroenterol Hepatol 2019 1;7(4):763-781. Epub 2019 Mar 1.

Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China; Sam and Ann Barshop Institute for Longevity and Aging Studies, Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jcmgh.2019.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463126PMC
March 2019

Interventional Photothermal Therapy Enhanced Brachytherapy: A New Strategy to Fight Deep Pancreatic Cancer.

Adv Sci (Weinh) 2019 Mar 15;6(5):1801507. Epub 2019 Jan 15.

Beijing Advanced Innovation Center for Soft Matter Science and Engineering State Key Laboratory of Organic-Inorganic Composites Bionanomaterials & Translational Engineering Laboratory Beijing Key Laboratory of Bioprocess Beijing Laboratory of Biomedical Materials Beijing University of Chemical Technology Beijing 100029 China.

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http://dx.doi.org/10.1002/advs.201801507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402393PMC
March 2019

Structural Insights for Anti-Influenza Vaccine Design.

Comput Struct Biotechnol J 2019 23;17:475-483. Epub 2019 Mar 23.

The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, China.

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https://linkinghub.elsevier.com/retrieve/pii/S20010370183030
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http://dx.doi.org/10.1016/j.csbj.2019.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458449PMC
March 2019

Lipidomics Profiling of Myelin.

Methods Mol Biol 2018 ;1791:37-50

Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio, San Antonio, TX, USA.

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http://link.springer.com/10.1007/978-1-4939-7862-5_4
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http://dx.doi.org/10.1007/978-1-4939-7862-5_4DOI Listing
February 2019

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers.

Alzheimers Dement 2019 Feb 15;15(2):232-244. Epub 2018 Oct 15.

Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA; Duke Institute of Brain Sciences, Duke University, Durham, NC, USA; Department of Medicine, Duke University, Durham, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454538PMC
February 2019

Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis.

Cell Metab 2019 Feb 15;29(2):383-398.e7. Epub 2018 Nov 15.

Division of Molecular Medicine, Department of Medicine, University of Minnesota, 401 East River Parkway, MMC 194, Minneapolis, MN 55455, USA; Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827, USA; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131183064
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http://dx.doi.org/10.1016/j.cmet.2018.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559243PMC
February 2019

Is the clinical lipidomics a potential goldmine?

Cell Biol Toxicol 2018 12 21;34(6):421-423. Epub 2018 Jul 21.

Zhongshan Hospital Institute of Clinical Science, Shanghai Institute of Clinical Bioinformatics, Fudan University Shanghai Medical School, Shanghai, China.

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http://link.springer.com/10.1007/s10565-018-9441-1
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http://dx.doi.org/10.1007/s10565-018-9441-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208904PMC
December 2018

Lipidomics reveals a systemic energy deficient state that precedes neurotoxicity in neonatal monkeys after sevoflurane exposure.

Anal Chim Acta 2018 Dec 30;1037:87-96. Epub 2017 Nov 30.

Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, TX 78229, USA; Department of Medicine, Division of Diabetes, University of Texas Health Science Center at San Antonio, TX 78229, USA; Department of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, TX 78229, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00032670173133
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http://dx.doi.org/10.1016/j.aca.2017.11.052DOI Listing
December 2018

SREBP-1a-stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1.

Proc Natl Acad Sci U S A 2018 12 10;115(52):E12228-E12234. Epub 2018 Dec 10.

Institute for Fundamental Biomedical Research, Johns Hopkins University School of Medicine, St. Petersburg, FL 33701;

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http://dx.doi.org/10.1073/pnas.1813458115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310840PMC
December 2018

Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity.

Cell Rep 2018 Dec;25(12):3283-3298.e6

Division of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183185
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http://dx.doi.org/10.1016/j.celrep.2018.11.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377366PMC
December 2018

Isotope Tracing Untargeted Metabolomics Reveals Macrophage Polarization-State-Specific Metabolic Coordination across Intracellular Compartments.

iScience 2018 Nov 2;9:298-313. Epub 2018 Nov 2.

Division of Molecular Medicine, Department of Medicine, University of Minnesota, 401 East River Parkway, MMC 194, Minneapolis, MN 55455, USA; Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827, USA; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S25890042183018
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http://dx.doi.org/10.1016/j.isci.2018.10.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240706PMC
November 2018

Lipidomic analysis reveals significant lipogenesis and accumulation of lipotoxic components in ob/ob mouse organs.

Prostaglandins Leukot Essent Fatty Acids 2018 09 11;136:161-169. Epub 2017 Jan 11.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827, USA. Electronic address:

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http://dx.doi.org/10.1016/j.plefa.2017.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203299PMC
September 2018

Lipid profiling as an effective approach for identifying biomarkers/adverse events associated with pediatric anesthesia.

Toxicol Appl Pharmacol 2018 09 15;354:191-195. Epub 2018 Mar 15.

National Center for Toxicological Research/Food and Drug Administration, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1016/j.taap.2018.03.017DOI Listing
September 2018

Lipidomics Reveals Changes in Metabolism, Indicative of Anesthetic-Induced Neurotoxicity in Developing Brains.

Chem Res Toxicol 2018 09 4;31(9):825-835. Epub 2018 Sep 4.

Department of Anesthesiology , Central Arkansas Veterans Health System , 4300 West Seventh Street, VA 704-110 , Little Rock , Arkansas 72205 , United States.

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http://dx.doi.org/10.1021/acs.chemrestox.8b00186DOI Listing
September 2018

Robotic enucleation for pediatric insulinoma with MEN1 syndrome: a case report and literature review.

BMC Surg 2018 Jun 19;18(1):44. Epub 2018 Jun 19.

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1186/s12893-018-0376-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009035PMC
June 2018

Hepatic ketogenic insufficiency reprograms hepatic glycogen metabolism and the lipidome.

JCI Insight 2018 Jun 21;3(12). Epub 2018 Jun 21.

Division of Molecular Medicine, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1172/jci.insight.99762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124396PMC
June 2018

A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction.

Mol Metab 2018 03 31;9:43-56. Epub 2018 Jan 31.

Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, United States; Gerald J. and Dorothy R. Friedman School of Nutrition Science & Policy, Tufts University, Boston, MA 02111, United States. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2018.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870107PMC
March 2018

Enhanced coverage of lipid analysis and imaging by matrix-assisted laser desorption/ionization mass spectrometry via a strategy with an optimized mixture of matrices.

Anal Chim Acta 2018 Feb 17;1000:155-162. Epub 2017 Oct 17.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827, United States. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2017.09.046DOI Listing
February 2018

The effect of somatostatin analogues on postoperative outcomes following pancreatic surgery: A meta-analysis.

PLoS One 2017 6;12(12):e0188928. Epub 2017 Dec 6.

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0188928PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718483PMC
December 2017

Selection of internal standards for accurate quantification of complex lipid species in biological extracts by electrospray ionization mass spectrometry-What, how and why?

Mass Spectrom Rev 2017 11 15;36(6):693-714. Epub 2016 Jan 15.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827.

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http://dx.doi.org/10.1002/mas.21492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947032PMC
November 2017

Furan fatty acids - Beneficial or harmful to health?

Prog Lipid Res 2017 10 16;68:119-137. Epub 2017 Oct 16.

School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China; Guangdong Research Center of Lipid Science and Applied Engineering Technology, South China University of Technology, Guangzhou 510640, China; Research Institute for Food Nutrition and Human Health, Guangzhou 510640, China. Electronic address:

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http://dx.doi.org/10.1016/j.plipres.2017.10.002DOI Listing
October 2017

MicroRNA-211 Regulates Oxidative Phosphorylation and Energy Metabolism in Human Vitiligo.

J Invest Dermatol 2017 09 11;137(9):1965-1974. Epub 2017 May 11.

Sanford Burnham Prebys Medical Discovery Institute, 6400 Sanger Road, Orlando, Florida, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233982PMC
September 2017

Lipidomics for precision medicine and metabolism: A personal view.

Authors:
Xianlin Han

Biochim Biophys Acta Mol Cell Biol Lipids 2017 Aug 24;1862(8):804-807. Epub 2017 Feb 24.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, 6400 Sanger Road, Orlando, FL 32827, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2017.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476489PMC
August 2017

Shotgun lipidomics in substantiating lipid peroxidation in redox biology: Methods and applications.

Redox Biol 2017 08 24;12:946-955. Epub 2017 Apr 24.

College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China; Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827, USA. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2017.04.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423350PMC
August 2017

Strategy for Quantitative Analysis of Isomeric Bis(monoacylglycero)phosphate and Phosphatidylglycerol Species by Shotgun Lipidomics after One-Step Methylation.

Anal Chem 2017 08 26;89(16):8490-8495. Epub 2017 Jul 26.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute , Orlando, Florida 32827, United States.

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http://dx.doi.org/10.1021/acs.analchem.7b02058DOI Listing
August 2017

A Soluble Fluorescent Binding Assay Reveals PIP Antagonism of TREK-1 Channels.

Cell Rep 2017 08;20(6):1287-1294

Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247173100
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http://dx.doi.org/10.1016/j.celrep.2017.07.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586213PMC
August 2017

Deletion of Nampt in Projection Neurons of Adult Mice Leads to Motor Dysfunction, Neurodegeneration, and Death.

Cell Rep 2017 Aug;20(9):2184-2200

Department of Bioengineering, University of Missouri, Columbia, MO 65211, USA; Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.08.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021762PMC
August 2017

Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A in a spatial-specific manner.

Acta Neuropathol Commun 2017 07 27;5(1):56. Epub 2017 Jul 27.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, 6400 Sanger Road, Orlando, FL, 32827, USA.

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http://dx.doi.org/10.1186/s40478-017-0460-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530945PMC
July 2017

A Novel Curative Treatment Strategy for Patients with Lower Grade Rectal Gastrointestinal Stromal Tumor: Chemoreduction Combined with Transanal Endoscopic Microsurgery.

J Laparoendosc Adv Surg Tech A 2017 Jun 30;27(6):579-585. Epub 2017 Mar 30.

1 Department of General Surgery, Peking Union Medical College Hospital , Beijing, China .

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http://www.liebertpub.com/doi/10.1089/lap.2017.0051
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http://dx.doi.org/10.1089/lap.2017.0051DOI Listing
June 2017

Coexpression Analysis of Transcriptome on AIDS and Other Human Disease Pathways by Canonical Correlation Analysis.

Int J Genomics 2017 14;2017:9163719. Epub 2017 Jun 14.

The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, China.

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https://www.hindawi.com/journals/ijg/2017/9163719/
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http://dx.doi.org/10.1155/2017/9163719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488239PMC
June 2017

High-Throughput Lipidomic and Transcriptomic Analysis To Compare SP2/0, CHO, and HEK-293 Mammalian Cell Lines.

Anal Chem 2017 02 9;89(3):1477-1485. Epub 2017 Jan 9.

Department of Chemical and Biomolecular Engineering, Johns Hopkins University , Baltimore, Maryland 21218, United States.

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http://dx.doi.org/10.1021/acs.analchem.6b02984DOI Listing
February 2017

Lipid profile of platelets and platelet-derived microparticles in ovarian cancer.

BBA Clin 2016 Dec 30;6:76-81. Epub 2016 Jun 30.

Department of Benign Hematology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.bbacli.2016.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941562PMC
December 2016

Oxidative stress leads to reduction of plasmalogen serving as a novel biomarker for systemic lupus erythematosus.

Free Radic Biol Med 2016 12 9;101:475-481. Epub 2016 Nov 9.

College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.11.006DOI Listing
December 2016

Comprehensive and Quantitative Analysis of Polyphosphoinositide Species by Shotgun Lipidomics Revealed Their Alterations in db/db Mouse Brain.

Anal Chem 2016 12 1;88(24):12137-12144. Epub 2016 Dec 1.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute , Orlando, Florida 32827, United States.

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http://dx.doi.org/10.1021/acs.analchem.6b02947DOI Listing
December 2016

Lipidomics for studying metabolism.

Authors:
Xianlin Han

Nat Rev Endocrinol 2016 Nov 29;12(11):668-679. Epub 2016 Jul 29.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, 6400 Sanger Road, Orlando, Florida 32827, USA and College of Basic Medical Sciences, Zhejiang Chinese Medical University, 548 Bingwen Road, Hangzhou, Zhejiang 310053, China.

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http://dx.doi.org/10.1038/nrendo.2016.98DOI Listing
November 2016

Lipidomics: Techniques, Applications, and Outcomes Related to Biomedical Sciences.

Trends Biochem Sci 2016 11 20;41(11):954-969. Epub 2016 Sep 20.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, Florida 32827, USA; College of Basic Medical Sciences, Zhejiang Chinese Medical University, 548 Bingwen Road, Hangzhou, Zhejiang 310053, China. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085849PMC
http://dx.doi.org/10.1016/j.tibs.2016.08.010DOI Listing
November 2016

Novel molecular insights into the critical role of sulfatide in myelin maintenance/function.

J Neurochem 2016 10 15;139(1):40-54. Epub 2016 Aug 15.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, Florida, USA.

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http://dx.doi.org/10.1111/jnc.13738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037006PMC
October 2016

One case of rare gastric cancer combined with lack of factor XI.

Blood Coagul Fibrinolysis 2016 Jul;27(5):583-4

Department of General Surgery, Peking Union Medical College Hospital, Beijing, China.

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http://dx.doi.org/10.1097/MBC.0000000000000495DOI Listing
July 2016

Improved Butanol-Methanol (BUME) Method by Replacing Acetic Acid for Lipid Extraction of Biological Samples.

Lipids 2016 07 31;51(7):887-96. Epub 2016 May 31.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL, 32827, USA.

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http://dx.doi.org/10.1007/s11745-016-4164-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904733PMC
July 2016

Discovering a critical transition state from nonalcoholic hepatosteatosis to nonalcoholic steatohepatitis by lipidomics and dynamical network biomarkers.

J Mol Cell Biol 2016 06 18;8(3):195-206. Epub 2016 Mar 18.

Key Laboratory of Food Safety Research, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), Shanghai 200031, China University of the Chinese Academy of Sciences, CAS, Beijing 100049, China School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China Key Laboratory of Food Safety Risk Assessment, Ministry of Health, Beijing 100021, China

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http://dx.doi.org/10.1093/jmcb/mjw016DOI Listing
June 2016

2015 ASMS Fall Workshop: Lipids and Lipidomics.

J Am Soc Mass Spectrom 2016 May;27(5):753-6

Sanford Burnham Prebys Medical Discovery Institute-Lake Nona, Orlando, Florida, USA.

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http://link.springer.com/10.1007/s13361-016-1373-5
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http://dx.doi.org/10.1007/s13361-016-1373-5DOI Listing
May 2016

Lipidomics Analyses Reveal Temporal and Spatial Lipid Organization and Uncover Daily Oscillations in Intracellular Organelles.

Mol Cell 2016 05 5;62(4):636-48. Epub 2016 May 5.

Department of Biomolecular Sciences, Weizmann Institute of Science, 7610001 Rehovot, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.04.002DOI Listing
May 2016

Advanced Shotgun Lipidomics for Characterization of Altered Lipid Patterns in Neurodegenerative Diseases and Brain Injury.

Methods Mol Biol 2016 ;1303:405-22

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, 6400 Sanger Road, Orlando, FL, 32827, USA.

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http://dx.doi.org/10.1007/978-1-4939-2627-5_24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780753PMC
April 2016

Novel advances in shotgun lipidomics for biology and medicine.

Prog Lipid Res 2016 Jan 15;61:83-108. Epub 2015 Dec 15.

Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute; Orlando, FL 32827, USA; College of Basic Medical Sciences, Zhejiang Chinese Medical University, 548 Bingwen Road, Hangzhou, Zhejiang 310053, China. Electronic address:

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http://dx.doi.org/10.1016/j.plipres.2015.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733395PMC
January 2016

Profiling and relative quantification of phosphatidylethanolamine based on acetone stable isotope derivatization.

Anal Chim Acta 2016 Jan 17;902:142-153. Epub 2015 Nov 17.

Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Key Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture, PR China; Hubei Key Laboratory of Lipid Chemistry and Nutrition, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2015.11.003DOI Listing
January 2016

[Combination of intraoperative ultrasonography for localizing insulinoma under Da Vinci robotic surgical system: experience of a single center in 50 cases].

Zhonghua Wai Ke Za Zhi 2016 Jan;54(1):30-3

Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

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http://dx.doi.org/10.3760/cma.j.issn.0529-5815.2016.01.008DOI Listing
January 2016

Comprehensive and quantitative analysis of lysophospholipid molecular species present in obese mouse liver by shotgun lipidomics.

Anal Chem 2015 22;87(9):4879-87. Epub 2015 Apr 22.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, Orlando, Florida 32827, United States.

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http://dx.doi.org/10.1021/acs.analchem.5b00410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657943PMC
November 2015

Bendavia restores mitochondrial energy metabolism gene expression and suppresses cardiac fibrosis in the border zone of the infarcted heart.

Life Sci 2015 Nov 6;141:170-8. Epub 2015 Oct 6.

Huntington Medical Research Institutes, Pasadena, CA, United States; Heart Institute, Good Samaritan Hospital, Los Angeles, CA, United States; Division of Cardiovascular Medicine of the Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.

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http://dx.doi.org/10.1016/j.lfs.2015.09.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973309PMC
November 2015

Potential Adverse Effects of Prolonged Sevoflurane Exposure on Developing Monkey Brain: From Abnormal Lipid Metabolism to Neuronal Damage.

Toxicol Sci 2015 Oct 23;147(2):562-72. Epub 2015 Jul 23.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute at Lake Nona, Orlando, FL 32827; and.

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http://dx.doi.org/10.1093/toxsci/kfv150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707202PMC
October 2015

Examining influence of violence against physicians on Chinese medical students' career choice.

Chin Med J (Engl) 2014 ;127(24):4287-9

Department of General Surgery, Peking Union Medical College Hospital, Beijing 100730, China. Email:

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August 2015

Improved method for quantitative analysis of methylated phosphatidylethanolamine species and its application for analysis of diabetic-mouse liver samples.

Anal Bioanal Chem 2015 Jul 1;407(17):5021-32. Epub 2015 Mar 1.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, 6400 Sanger Road, Orlando, FL, 32827, USA.

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http://link.springer.com/10.1007/s00216-015-8534-4
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http://dx.doi.org/10.1007/s00216-015-8534-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474753PMC
July 2015

Mitochondria-targeted antioxidant prevents cardiac dysfunction induced by tafazzin gene knockdown in cardiac myocytes.

Oxid Med Cell Longev 2014 27;2014:654198. Epub 2014 Aug 27.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, 6400 Sanger Road, Orlando, FL 32827, USA.

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http://dx.doi.org/10.1155/2014/654198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160652PMC
June 2015

Multidimensional mass spectrometry-based shotgun lipidomics.

Methods Mol Biol 2014 ;1198:203-20

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, 6400 Sanger Road, Orlando, FL, 32827, USA.

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http://dx.doi.org/10.1007/978-1-4939-1258-2_13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261229PMC
June 2015

Impaired mitochondrial fat oxidation induces adaptive remodeling of muscle metabolism.

Proc Natl Acad Sci U S A 2015 Jun 8;112(25):E3300-9. Epub 2015 Jun 8.

Gene Nutrient Interactions Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808; Transgenic Core Facility, Pennington Biomedical Research Center, Baton Rouge, LA 70808;

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http://dx.doi.org/10.1073/pnas.1418560112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485116PMC
June 2015

Muscle-specific deletion of comparative gene identification-58 (CGI-58) causes muscle steatosis but improves insulin sensitivity in male mice.

Endocrinology 2015 May 9;156(5):1648-58. Epub 2015 Mar 9.

Departments of Biochemistry (P.X., Y.M., F.G., L.Y.) and Anesthesiology (L.G.), Wake Forest School of Medicine, Winston-Salem, North Carolina 27157; Department of Animal and Avian Sciences (A.K.G.G., Y.M., L.Y.), University of Maryland, College Park, Maryland 20742; Diabetes and Obesity Research Center (X.H., M.W.), Sanford-Burnham Medical Research Institute, Orlando, Florida 32827; Department of Biology (B.X., H.S.), Georgia State University, Atlanta, Georgia 30303; and The Key Laboratory of Remodeling-Related Cardiovascular Diseases (H.L.), Capital Medical University, Ministry of Education, Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing Anzhen Hospital Affiliated the Capital Medical University, Beijing 100029, People's Republic of China.

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http://dx.doi.org/10.1210/en.2014-1892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398773PMC
May 2015

Lipidomics revealed idiopathic pulmonary fibrosis-induced hepatic lipid disorders corrected with treatment of baicalin in a murine model.

AAPS J 2015 May 12;17(3):711-22. Epub 2015 Mar 12.

College of Basic Medical Sciences, Zhejiang Chinese Medical University, 548 Bingwen Road, Hangzhou, Zhejiang, 310053, China.

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http://dx.doi.org/10.1208/s12248-014-9714-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406959PMC
May 2015

Bis(monoacylglycero)phosphate: a secondary storage lipid in the gangliosidoses.

J Lipid Res 2015 May 20;56(5):1006-13. Epub 2015 Mar 20.

Department of Biology, Boston College, Chestnut Hill, MA 02467.

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http://dx.doi.org/10.1194/jlr.M057851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409277PMC
May 2015

Applications of mass spectrometry for cellular lipid analysis.

Mol Biosyst 2015 Mar 19;11(3):698-713. Epub 2015 Jan 19.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, 6400 Sanger Road, Orlando, Florida 32827, USA.

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http://dx.doi.org/10.1039/c4mb00586dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376555PMC
March 2015

Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver.

J Lipid Res 2014 Dec 11;55(12):2458-70. Epub 2014 Aug 11.

Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107.

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http://dx.doi.org/10.1194/jlr.M046961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242439PMC
December 2014

Accurate mass searching of individual lipid species candidates from high-resolution mass spectra for shotgun lipidomics.

Rapid Commun Mass Spectrom 2014 Oct;28(20):2201-10

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, Orlando, FL, 32827, USA.

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http://dx.doi.org/10.1002/rcm.7015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160105PMC
October 2014

Alterations in mouse brain lipidome after disruption of CST gene: a lipidomics study.

Mol Neurobiol 2014 Aug 7;50(1):88-96. Epub 2014 Jan 7.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, 6400 Sanger Road, Orlando, FL, 32827, USA.

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http://dx.doi.org/10.1007/s12035-013-8626-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085157PMC
August 2014

Synthesis and biological evaluation of antimetastatic agents predicated upon dihydromotuporamine C and its carbocyclic derivatives.

J Med Chem 2014 May 2;57(10):4023-34. Epub 2014 May 2.

Department of Chemistry, University of Central Florida , Orlando, Florida 32816, United States.

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http://dx.doi.org/10.1021/jm401906vDOI Listing
May 2014

Cardiolipin remodeling in diabetic heart.

Authors:
Quan He Xianlin Han

Chem Phys Lipids 2014 Apr 1;179:75-81. Epub 2013 Nov 1.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, Orlando, FL 32827, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chemphyslip.2013.10.007DOI Listing
April 2014

Characterization and quantification of diacylglycerol species in biological extracts after one-step derivatization: a shotgun lipidomics approach.

Anal Chem 2014 Feb 28;86(4):2146-55. Epub 2014 Jan 28.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, Orlando, FL 32827.

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http://dx.doi.org/10.1021/ac403798qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954745PMC
February 2014

Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides.

Cell Metab 2014 Feb;19(2):319-30

Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2013.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261230PMC
February 2014

Quantitative profiling and pattern analysis of triacylglycerol species in Arabidopsis seeds by electrospray ionization mass spectrometry.

Plant J 2014 Jan 29;77(1):160-72. Epub 2013 Nov 29.

Department of Biology, University of Missouri, St. Louis, MO, 63121, USA; Donald Danforth Plant Science Center, St. Louis, MO, 63132, USA.

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http://dx.doi.org/10.1111/tpj.12365DOI Listing
January 2014

Unremodeled and remodeled cardiolipin are functionally indistinguishable in yeast.

J Biol Chem 2014 Jan 27;289(3):1768-78. Epub 2013 Nov 27.

From the Department of Physiology, The Johns Hopkins School of Medicine, Baltimore, Maryland 21205.

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http://dx.doi.org/10.1074/jbc.M113.525733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894353PMC
January 2014

A role for peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1) in the regulation of cardiac mitochondrial phospholipid biosynthesis.

J Biol Chem 2014 Jan 11;289(4):2250-9. Epub 2013 Dec 11.

From the Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, Orlando, Florida 32827.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M113.523654
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http://dx.doi.org/10.1074/jbc.M113.523654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900969PMC
January 2014

Specific changes of sulfatide levels in individuals with pre-clinical Alzheimer's disease: an early event in disease pathogenesis.

J Neurochem 2013 Dec 30;127(6):733-8. Epub 2013 Jul 30.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, Orlando, Florida, USA.

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http://dx.doi.org/10.1111/jnc.12368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844035PMC
December 2013

Rotenone induces reductive stress and triacylglycerol deposition in C2C12 cells.

Int J Biochem Cell Biol 2013 Dec 5;45(12):2749-55. Epub 2013 Oct 5.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, Orlando, FL 32827, USA.

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http://dx.doi.org/10.1016/j.biocel.2013.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846609PMC
December 2013

Tafazzin knockdown interrupts cell cycle progression in cultured neonatal ventricular fibroblasts.

Am J Physiol Heart Circ Physiol 2013 Nov 30;305(9):H1332-43. Epub 2013 Aug 30.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, Orlando, Florida; and.

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http://dx.doi.org/10.1152/ajpheart.00084.2013DOI Listing
November 2013

Fatty acidomics: global analysis of lipid species containing a carboxyl group with a charge-remote fragmentation-assisted approach.

Anal Chem 2013 Oct 9;85(19):9312-20. Epub 2013 Sep 9.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute , Orlando, Florida 32827, United States.

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http://dx.doi.org/10.1021/ac402078pDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826454PMC
October 2013