Xiangyun Amy Chen

Xiangyun Amy Chen

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Xiangyun Amy Chen

Xiangyun Amy Chen

Publications by authors named "Xiangyun Amy Chen"

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7Publications

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Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons.

Cell Stem Cell 2015 Dec 17;17(6):735-747. Epub 2015 Oct 17.

Department of Biology, Huck Institutes of Life Sciences, Pennsylvania State University, University Park, PA 16802, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675726PMC
December 2015

ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple-Negative Breast Cancer Cells.

Mol Cancer Ther 2015 Apr 22;14(4):877-88. Epub 2015 Jan 22.

Center for Eukaryotic Gene Regulation, Department of Biochemistry and Molecular Biology, Pennsylvania State University, State College, Pennsylvania.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-1093-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394025PMC
April 2015

A comprehensive and high-resolution genome-wide response of p53 to stress.

Cell Rep 2014 Jul 17;8(2):514-27. Epub 2014 Jul 17.

Center for Eukaryotic Gene Regulation, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA; Center for Comparative Genomics and Bioinformatics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.06.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113076PMC
July 2014

Folded Conformation, Cyclic Pentamer, Nano-Structure and PAD4 Binding Mode of YW3-56.

J Phys Chem C Nanomater Interfaces 2013 May;117(19):10070-10078

College of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, P.R. China.

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http://dx.doi.org/10.1021/jp311726kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685498PMC
May 2013

PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures.

Front Immunol 2012 4;3:307. Epub 2012 Oct 4.

Department of Biochemistry and Molecular Biology, Center for Eukaryotic Gene Regulation, Pennsylvania State University, University Park PA, USA.

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http://dx.doi.org/10.3389/fimmu.2012.00307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463874PMC
October 2012

Anticancer peptidylarginine deiminase (PAD) inhibitors regulate the autophagy flux and the mammalian target of rapamycin complex 1 activity.

J Biol Chem 2012 Jul 17;287(31):25941-53. Epub 2012 May 17.

Center for Eukaryotic Gene Regulation, Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M112.375725
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http://dx.doi.org/10.1074/jbc.M112.375725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406678PMC
July 2012

Cofilin aggregation blocks intracellular trafficking and induces synaptic loss in hippocampal neurons.

J Biol Chem 2012 Feb 19;287(6):3919-29. Epub 2011 Dec 19.

Department of Biology, Huck Institutes of Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://dx.doi.org/10.1074/jbc.M111.301911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281697PMC
February 2012