Xiangyang Wang

Xiangyang Wang

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Rapid, quantitative determination of aggregation and particle formation for antibody drug conjugate therapeutics with label-free Raman spectroscopy.

Anal Chim Acta 2019 Nov 10;1081:138-145. Epub 2019 Jul 10.

Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, USA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Radiology & Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2019.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750807PMC
November 2019

Activation of Nrf2/HO-1 signal with Myricetin for attenuating ECM degradation in human chondrocytes and ameliorating the murine osteoarthritis.

Int Immunopharmacol 2019 Oct 17;75:105742. Epub 2019 Jul 17.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, West Xueyuan Road 109#, Wenzhou 325027, Zhejiang Province, China; Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang Province, China; The Second School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang Province, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2019.105742DOI Listing
October 2019

SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis.

Int J Biol Sci 2018 20;14(13):1873-1882. Epub 2018 Oct 20.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang, China.

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http://dx.doi.org/10.7150/ijbs.27746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231225PMC
September 2019

Environmental impacts of resource recovery from wastewater treatment plants.

Water Res 2019 Sep 25;160:268-277. Epub 2019 May 25.

Beijing Capital Co., Ltd, 21 Chegongzhuang Street, Xicheng District, Beijing, 100044, PR China.

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http://dx.doi.org/10.1016/j.watres.2019.05.068DOI Listing
September 2019

Isofraxidin attenuates IL-1β-induced inflammatory response in human nucleus pulposus cells.

J Cell Biochem 2019 Aug 19;120(8):13302-13309. Epub 2019 Mar 19.

Spine Area of Orthopedics, Xi'an Hospital of Traditional Chinese Medicine, Xi'an, China.

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http://dx.doi.org/10.1002/jcb.28604DOI Listing
August 2019

Stabilization of Hypoxia Inducible Factor-1α by Dimethyloxalylglycine Promotes Recovery from Acute Spinal Cord Injury by Inhibiting Neural Apoptosis and Enhancing Axon Regeneration.

J Neurotrauma 2019 Aug 1. Epub 2019 Aug 1.

1Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

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http://dx.doi.org/10.1089/neu.2018.6364DOI Listing
August 2019

Troxerutin suppresses the inflammatory response in advanced glycation end-product-administered chondrocytes and attenuates mouse osteoarthritis development.

Food Funct 2019 Aug 30;10(8):5059-5069. Epub 2019 Jul 30.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

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http://dx.doi.org/10.1039/c9fo01089kDOI Listing
August 2019

The homogeneous and heterogeneous risk factors for occurrence and prognosis in lung cancer patients with bone metastasis.

J Bone Oncol 2019 Aug 9;17:100251. Epub 2019 Jul 9.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang, China.

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http://dx.doi.org/10.1016/j.jbo.2019.100251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661364PMC
August 2019

Postmitotic annulate lamellae assembly contributes to nuclear envelope reconstitution in daughter cells.

J Biol Chem 2019 Jul 31;294(27):10383-10391. Epub 2019 May 31.

From the Ministry of Education Key Laboratory of Cell Proliferation and Differentiation and the State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing 100871, China

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http://dx.doi.org/10.1074/jbc.AC119.008171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615687PMC
July 2019

Design of a Purely Mechanical Sensor-Controller Integrated System for Walking Assistance on an Ankle-Foot Exoskeleton.

Sensors (Basel) 2019 Jul 19;19(14). Epub 2019 Jul 19.

Robotics Research Center, School of Mechanical, Electronic and Control Engineering, Beijing Jiaotong University, Beijing 100044, China.

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http://dx.doi.org/10.3390/s19143196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679259PMC
July 2019

BRD4 inhibition regulates MAPK, NF-κB signals, and autophagy to suppress MMP-13 expression in diabetic intervertebral disc degeneration.

FASEB J 2019 Jul 22:fj201900703R. Epub 2019 Jul 22.

Department of Orthopaedics, The Second Affiliated Hospital-Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

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http://dx.doi.org/10.1096/fj.201900703RDOI Listing
July 2019

Berberine suppresses apoptosis and extracellular matrix (ECM) degradation in nucleus pulposus cells and ameliorates disc degeneration in a rodent model.

Int J Biol Sci 2018 30;14(6):682-692. Epub 2018 Apr 30.

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 325027 Wenzhou, China.

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http://dx.doi.org/10.7150/ijbs.24081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001656PMC
June 2019

Incidence and risk factors of facet joint violation following percutaneous kyphoplasty for osteoporotic vertebral compression fractures.

Acta Radiol 2019 Jun 11;60(6):755-761. Epub 2018 Sep 11.

1 Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, PR China.

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http://dx.doi.org/10.1177/0284185118799515DOI Listing
June 2019

Baicalein Inhibits the IL-1β-Induced Inflammatory Response in Nucleus Pulposus Cells and Attenuates Disc Degeneration In vivo.

Inflammation 2019 Jun;42(3):1032-1044

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

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http://dx.doi.org/10.1007/s10753-019-00965-8DOI Listing
June 2019

In Operando Probing of Lithium-Ion Storage on Single-Layer Graphene.

Adv Mater 2019 Jun 11;31(23):e1808091. Epub 2019 Apr 11.

Hefei National Research Center for Physical Sciences at the Microscale, CAS Key Laboratory of Materials for Energy Conversion, Department of Materials Science and Engineering, i-ChEM (Collaborative Innovation Center of Chemistry for Energy Materials), University of Science and Technology of China, 96 Jin Zhai Rd., Hefei, Anhui, 230026, P. R. China.

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http://dx.doi.org/10.1002/adma.201808091DOI Listing
June 2019

MicroRNA-30c abrogation protects against spinal cord ischemia reperfusion injury through modulating SIRT1.

Eur J Pharmacol 2019 May 16;851:80-87. Epub 2019 Feb 16.

Spine Area of Orthopedics, Xi'an Hospital of Traditional Chinese Medicine, 710021 Shaanxi, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2019.02.027DOI Listing
May 2019

BRD4 inhibition attenuates inflammatory response in microglia and facilitates recovery after spinal cord injury in rats.

J Cell Mol Med 2019 May 26;23(5):3214-3223. Epub 2019 Feb 26.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

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http://dx.doi.org/10.1111/jcmm.14196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484335PMC
May 2019

Simultaneous determination of three saponins in human plasma after oral administration of compound danshen dripping pills by LC-MS/MS and its application in a pharmacokinetic study.

J Pharm Biomed Anal 2019 May 5;169:254-259. Epub 2019 Mar 5.

Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin 300410, China; State Key Laboratory of Core Technology in Innovation Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin 300410, China; Tasly Pharmaceuticals Inc, Rockville, MD 20850, USA.

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http://dx.doi.org/10.1016/j.jpba.2019.03.008DOI Listing
May 2019

Polymorphonuclear myeloid-derived suppressor cells attenuate allergic airway inflammation by negatively regulating group 2 innate lymphoid cells.

Immunology 2019 04 17;156(4):402-412. Epub 2019 Jan 17.

Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.

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http://dx.doi.org/10.1111/imm.13040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418421PMC
April 2019

Ligustilide alleviated IL-1β induced apoptosis and extracellular matrix degradation of nucleus pulposus cells and attenuates intervertebral disc degeneration in vivo.

Int Immunopharmacol 2019 Apr 18;69:398-407. Epub 2019 Feb 18.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, West Xueyuan Road 109#, Wenzhou 325027, Zhejiang Province, China; Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang Province, China; The Second School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang Province, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2019.01.004DOI Listing
April 2019

Isolation and identification of nucleosides/nucleotides raising testosterone and NO levels of mice serum from Chinese chive (Allium tuberosum) leaves.

Andrologia 2019 Mar 5;51(2):e13191. Epub 2018 Nov 5.

College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, China.

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http://doi.wiley.com/10.1111/and.13191
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http://dx.doi.org/10.1111/and.13191DOI Listing
March 2019

Melatonin ameliorates intervertebral disc degeneration via the potential mechanisms of mitophagy induction and apoptosis inhibition.

J Cell Mol Med 2019 Mar 4;23(3):2136-2148. Epub 2019 Jan 4.

Department of Orthopaedic Surgery, The Second Afliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

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http://doi.wiley.com/10.1111/jcmm.14125
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http://dx.doi.org/10.1111/jcmm.14125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378230PMC
March 2019

The Presence of Thyroid Cartilage at the Surgical Level Reduces Early Dysphagia after Single-Level Anterior Cervical Surgery: A Retrospective Study.

J Invest Surg 2019 Mar 19:1-10. Epub 2019 Mar 19.

b Department of Orthopaedic Surgery , The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Zhejiang Spine Surgery Centre, , Wenzhou , PR China.

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http://dx.doi.org/10.1080/08941939.2018.1520939DOI Listing
March 2019

TFEB protects nucleus pulposus cells against apoptosis and senescence via restoring autophagic flux.

Osteoarthritis Cartilage 2019 Feb 8;27(2):347-357. Epub 2018 Nov 8.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China; Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou 325000, Zhejiang Province, China; The Second School of Medicine, Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China; Chinese Orthopaedic Regenerative Medicine Society, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10634584183151
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http://dx.doi.org/10.1016/j.joca.2018.10.011DOI Listing
February 2019

Incorporating Flexibility into Stiffness: Self-Grown Carbon Nanotubes in Melamine Sponges Enable A Lithium-Metal-Anode Capacity of 15 mA h cm Cyclable at 15 mA cm.

Adv Mater 2019 Feb 14;31(7):e1805654. Epub 2018 Dec 14.

Hefei National Research Center for Physical Science at the Microscale, CAS Key Laboratory of Materials for Energy Conversion & Department of Materials Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, P. R. China.

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http://dx.doi.org/10.1002/adma.201805654DOI Listing
February 2019

Genistein protects intervertebral discs from degeneration via Nrf2-mediated antioxidant defense system: An in vitro and in vivo study.

J Cell Physiol 2019 Feb 18. Epub 2019 Feb 18.

Department of Orthopaedics Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

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http://doi.wiley.com/10.1002/jcp.28301
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http://dx.doi.org/10.1002/jcp.28301DOI Listing
February 2019

The Expansion of Myeloid-Derived Suppressor Cells Is Associated with Joint Inflammation in Rheumatic Patients with Arthritis.

Biomed Res Int 2018 26;2018:5474828. Epub 2018 Jun 26.

Department of Internal Medicine of Traditional Chinese Medicine, College of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China.

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http://dx.doi.org/10.1155/2018/5474828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038685PMC
January 2019

Schisandrin B attenuates epidural fibrosis in postlaminectomy rats by inhibiting proliferation and extracellular matrix production of fibroblasts.

Phytother Res 2019 Jan 22;33(1):107-116. Epub 2018 Oct 22.

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

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http://dx.doi.org/10.1002/ptr.6204DOI Listing
January 2019

Melatonin protects vertebral endplate chondrocytes against apoptosis and calcification via the Sirt1-autophagy pathway.

J Cell Mol Med 2019 Jan 24;23(1):177-193. Epub 2018 Oct 24.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.

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http://dx.doi.org/10.1111/jcmm.13903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307776PMC
January 2019

Evodiamine inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in mice.

J Cell Mol Med 2019 Jan 19;23(1):522-534. Epub 2018 Nov 19.

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

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http://doi.wiley.com/10.1111/jcmm.13955
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http://dx.doi.org/10.1111/jcmm.13955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307789PMC
January 2019

Comparison of enhanced male mice sexual function among three medicinal materials.

Andrologia 2018 Nov 10;50(9):e13087. Epub 2018 Jul 10.

College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, China.

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http://dx.doi.org/10.1111/and.13087DOI Listing
November 2018

The Impact of Facet Joint Violation on Clinical Outcomes After Percutaneous Kyphoplasty for Osteoporotic Vertebral Compression Fractures.

World Neurosurg 2018 Nov 30;119:e383-e388. Epub 2018 Jul 30.

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2018.07.170DOI Listing
November 2018

Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats.

J Cell Mol Med 2018 11 30;22(11):5720-5731. Epub 2018 Aug 30.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

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http://doi.wiley.com/10.1111/jcmm.13848
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http://dx.doi.org/10.1111/jcmm.13848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201341PMC
November 2018

Small molecule natural compound agonist of SIRT3 as a therapeutic target for the treatment of intervertebral disc degeneration.

Exp Mol Med 2018 11 12;50(11):146. Epub 2018 Nov 12.

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou,, 325027, Zhejiang, China.

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http://dx.doi.org/10.1038/s12276-018-0173-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232087PMC
November 2018

Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice.

Exp Mol Med 2018 11 21;50(11):154. Epub 2018 Nov 21.

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

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http://dx.doi.org/10.1038/s12276-018-0177-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249246PMC
November 2018

Correlation of Interpedicular Distance with Radiographic Parameters, Neurologic Deficit, and Posterior Structures Injury in Thoracolumbar Burst Fractures.

World Neurosurg 2018 Oct 23;118:e72-e78. Epub 2018 Jun 23.

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2018.06.122DOI Listing
October 2018

Therapeutic Potential of Naringin for Intervertebral Disc Degeneration: Involvement of Autophagy Against Oxidative Stress-Induced Apoptosis in Nucleus Pulposus Cells.

Am J Chin Med 2018 Oct 4:1-20. Epub 2018 Oct 4.

* Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's, Hospital of Wenzhou Medical University, 109 West Xueyuan Road, Wenzhou 325027, Zhejiang Province, P. R. China.

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https://www.worldscientific.com/doi/abs/10.1142/S0192415X185
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http://dx.doi.org/10.1142/S0192415X18500805DOI Listing
October 2018

Perilaldehyde activates AMP-activated protein kinase to suppress the growth of gastric cancer via induction of autophagy.

J Cell Biochem 2018 Oct 30. Epub 2018 Oct 30.

Department of Gastroenterology and Clinical Nutrition, The First Affiliated Hospital (People's Hospital of Hunan Province), Hunan Normal University, Changsha, Hunan, China.

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http://doi.wiley.com/10.1002/jcb.27491
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http://dx.doi.org/10.1002/jcb.27491DOI Listing
October 2018

Parkin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.

Cell Death Dis 2018 09 24;9(10):980. Epub 2018 Sep 24.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, West Xueyuan Road 109#, Wenzhou, 325027, Zhejiang Province, China.

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http://www.nature.com/articles/s41419-018-1024-9
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http://dx.doi.org/10.1038/s41419-018-1024-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155159PMC
September 2018

TFEB, a potential therapeutic target for osteoarthritis via autophagy regulation.

Cell Death Dis 2018 08 28;9(9):858. Epub 2018 Aug 28.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China.

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http://dx.doi.org/10.1038/s41419-018-0909-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113230PMC
August 2018

Small bowel gastrointestinal stromal tumor: a retrospective study of 32 cases at a single center and review of the literature.

Ther Clin Risk Manag 2018 22;14:1467-1481. Epub 2018 Aug 22.

Department of Gastroenterology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, Peoples' Republic of China,

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http://dx.doi.org/10.2147/TCRM.S167248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110632PMC
August 2018

Multi-step high-throughput conjugation platform for the development of antibody-drug conjugates.

J Biotechnol 2018 Jul 4;278:48-55. Epub 2018 May 4.

Institute of Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology, Fritz-Haber-Weg 2, 76131 Karlsruhe, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01681656183014
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http://dx.doi.org/10.1016/j.jbiotec.2018.05.004DOI Listing
July 2018

Characterizing the Overall Derivatization of Conjugated Oligomeric Proteins.

PDA J Pharm Sci Technol 2017 Mar-Apr;71(2):115-126. Epub 2017 Mar 13.

Department of Nonclinical Biostatistics,

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http://dx.doi.org/10.5731/pdajpst.2016.006510DOI Listing
June 2018

Spermidine promotes nucleus pulposus autophagy as a protective mechanism against apoptosis and ameliorates disc degeneration.

J Cell Mol Med 2018 06 25;22(6):3086-3096. Epub 2018 Mar 25.

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

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http://dx.doi.org/10.1111/jcmm.13586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980193PMC
June 2018

Marital status and survival in patients with rectal cancer: An analysis of the Surveillance, Epidemiology and End Results (SEER) database.

Cancer Epidemiol 2018 06 16;54:119-124. Epub 2018 May 16.

Department of Coloproctology, The Second Affiliated Hospital of Wenzhou Medical University, China. Electronic address:

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http://dx.doi.org/10.1016/j.canep.2018.04.007DOI Listing
June 2018

Common variants in the GNL3 contribute to the increasing risk of knee osteoarthritis in Han Chinese population.

Sci Rep 2018 Jun 25;8(1):9610. Epub 2018 Jun 25.

The First Department of Orthopaedics, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

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http://dx.doi.org/10.1038/s41598-018-27971-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018215PMC
June 2018

A quality marker study on salvianolic acids for injection.

Phytomedicine 2018 May 10;44:138-147. Epub 2018 Feb 10.

The State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin - 300193, China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2018.02.003DOI Listing
May 2018

Metformin ameliorates BSCB disruption by inhibiting neutrophil infiltration and MMP-9 expression but not direct TJ proteins expression regulation.

J Cell Mol Med 2017 Dec 12;21(12):3322-3336. Epub 2017 Jul 12.

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.

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http://dx.doi.org/10.1111/jcmm.13235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706495PMC
December 2017

Insight into the interaction between chitosan and bovine serum albumin.

Carbohydr Polym 2017 Nov 18;176:75-82. Epub 2017 Aug 18.

Key Laboratory of Fruits and Vegetables Postharvest and Processing Technology, Research of Zhejiang Province, College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.carbpol.2017.08.068DOI Listing
November 2017

Simultaneous determination and pharmacokinetics of danshensu, protocatechuic aldehyde, 4-hydroxy-3-methyloxyphenyl lactic acid and protocatechuic acid in human plasma by LC-MS/MS after oral administration of Compound Danshen Dripping Pills.

J Pharm Biomed Anal 2017 Oct 1;145:860-864. Epub 2017 Jul 1.

Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin 300410, China; Skate Key Laboratory of Core Technology in Innovation Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin 300410, China; Tasly Pharmaceuticals Inc, Rockvill, MD 20850, USA.

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http://dx.doi.org/10.1016/j.jpba.2017.06.014DOI Listing
October 2017

Disease-Related Detection with Electrochemical Biosensors: A Review.

Sensors (Basel) 2017 Oct 17;17(10). Epub 2017 Oct 17.

Chongqing Key Laboratory of Non-linear Circuit and Intelligent Information Processing, College of Electronic and Information Engineering, Southwest University, Chongqing 400715, China.

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http://dx.doi.org/10.3390/s17102375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676665PMC
October 2017

Liraglutide activates autophagy GLP-1R to improve functional recovery after spinal cord injury.

Oncotarget 2017 Oct 8;8(49):85949-85968. Epub 2017 Sep 8.

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

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http://www.oncotarget.com/fulltext/20791
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http://dx.doi.org/10.18632/oncotarget.20791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689659PMC
October 2017

Stepwise resection of the posterior ligamentous complex for stability of a thoracolumbar compression fracture: An in vitro biomechanical investigation.

Medicine (Baltimore) 2017 Sep;96(35):e7873

aDepartment of Orthopedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou bDepartment of Orthopedic Surgery, The Second Affiliated Hospital of Jiaxing College, Jiaxing, China.

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http://Insights.ovid.com/crossref?an=00005792-201709010-0002
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http://dx.doi.org/10.1097/MD.0000000000007873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585492PMC
September 2017

Self-Focusing and the Talbot Effect in Conformal Transformation Optics.

Phys Rev Lett 2017 Jul 18;119(3):033902. Epub 2017 Jul 18.

National Laboratory of Solid State Microstructures and School of Physics, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing, Jiangsu 210093, China.

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http://dx.doi.org/10.1103/PhysRevLett.119.033902DOI Listing
July 2017

Simultaneous determination of tanshinol, protocatechuic aldehyde, protocatechuic acid, notoginsenoside R1, ginsenoside Rg1 and Rb1 in rat plasma by LC-MS/MS and its application.

Biomed Chromatogr 2017 Jun 5;31(6). Epub 2017 Feb 5.

State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin, China.

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http://dx.doi.org/10.1002/bmc.3889DOI Listing
June 2017

Hydrogen sulfide protects against endoplasmic reticulum stress and mitochondrial injury in nucleus pulposus cells and ameliorates intervertebral disc degeneration.

Pharmacol Res 2017 03 10;117:357-369. Epub 2017 Jan 10.

Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2017.01.005DOI Listing
March 2017

Liquid-liquid phase separation causes high turbidity and pressure during low pH elution process in Protein A chromatography.

J Chromatogr A 2017 Mar 28;1488:57-67. Epub 2017 Jan 28.

Purification Process Sciences, Medimmune LLC, One Medimmune Way, Gaithersburg, MD 20878, USA.

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http://dx.doi.org/10.1016/j.chroma.2017.01.067DOI Listing
March 2017

Therapeutic effect of apocynin through antioxidant activity and suppression of apoptosis and inflammation after spinal cord injury.

Exp Ther Med 2017 Mar 25;13(3):952-960. Epub 2017 Jan 25.

Department of TCM Orthopedics and Traumatology, Xi'an City Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi 710021, P.R. China.

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http://dx.doi.org/10.3892/etm.2017.4090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403360PMC
March 2017

Application of the Coflex Interlaminar Stabilization in Patients With L5/S1 Degenerative Diseases: Minimum 4-Year Follow-up.

Am J Ther 2016 Nov/Dec;23(6):e1813-e1818

Department of Orthopaedic Surgery, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

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http://dx.doi.org/10.1097/MJT.0000000000000333DOI Listing
February 2017

Camelid V H affinity ligands enable separation of closely related biopharmaceuticals.

Biotechnol J 2017 Feb 20;12(2). Epub 2016 Oct 20.

MedImmune, Department of Purification Process Sciences, Gaithersburg, MD, USA.

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http://dx.doi.org/10.1002/biot.201600357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333455PMC
February 2017

Complexity Analysis of Electroencephalogram Dynamics in Patients with Parkinson's Disease.

Parkinsons Dis 2017 20;2017:8701061. Epub 2017 Feb 20.

Department of Medical Imaging, Schulich School of Medicine and Dentistry, University of Western Ontario, 1151 Richmond St, London, ON, Canada.

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http://dx.doi.org/10.1155/2017/8701061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338074PMC
February 2017

Synthesis, characterization, and antimicrobial activities of sulfonated chitosan.

Carbohydr Polym 2017 Jan 22;155:321-328. Epub 2016 Aug 22.

Key Laboratory of Fruits and Vegetables Postharvest and Processing Technology Research of Zhejiang Province, College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.carbpol.2016.08.069DOI Listing
January 2017

Simultaneous Determination and Pharmacokinetic Study of Protocatechuic Aldehyde and Its Major Active Metabolite Protocatechuic Acid in Rat Plasma by Liquid Chromatography-Tandem Mass Spectrometry.

J Chromatogr Sci 2016 May-Jun;54(5):697-705. Epub 2016 Mar 10.

Tianjin State Key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.

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http://dx.doi.org/10.1093/chromsci/bmv240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890439PMC
December 2016

Effects of post-harvest stigmasterol treatment on quality-related parameters and antioxidant enzymes of green asparagus (Asparagus officinalis L.).

Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2016 Dec;33(12):1785-1792

b Institute of Food Science , Zhejiang Academy of Agricultural Sciences , Hangzhou , China.

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http://dx.doi.org/10.1080/19440049.2016.1241896DOI Listing
December 2016

Ultrasound assisted, thermally activated persulfate oxidation of coal tar DNAPLs.

J Hazard Mater 2016 Nov 6;318:497-506. Epub 2016 Jul 6.

Guangdong Provincial Key Lab of Functional-materials for Environmental Protection, School of Chemistry and Environment, South China Normal University, Guangzhou, Guangdong 510006, China. Electronic address:

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http://dx.doi.org/10.1016/j.jhazmat.2016.07.014DOI Listing
November 2016

Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer - A comprehensive review.

Eur J Med Chem 2016 Nov 29;123:577-595. Epub 2016 Jul 29.

State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin 300410, China; The State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China.

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http://dx.doi.org/10.1016/j.ejmech.2016.07.070DOI Listing
November 2016

Complete L₅ burst fracture treated by 270-degree decompression and reconstruction using titanium mesh cage via a single posterior vertebrectomy.

Chin J Traumatol 2014 ;17(5):307-10

Department of Orthopaedic Surgery, Taizhou Municipal Hospital, Taizhou 318000, Zhejiang Province, China.

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October 2016

Quantitative determination of periplocymarin in rat plasma and tissue by LC-MS/MS: application to pharmacokinetic and tissue distribution study.

Biomed Chromatogr 2016 Aug 15;30(8):1195-201. Epub 2016 Jan 15.

Tianjin State Key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin, 300193, China.

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http://dx.doi.org/10.1002/bmc.3667DOI Listing
August 2016

UFLC-MS/MS determination and pharmacokinetic studies of six Saikosaponins in rat plasma after oral administration of Bupleurum Dropping Pills.

J Pharm Biomed Anal 2016 May 6;124:288-293. Epub 2016 Mar 6.

Tianjin State Key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China.

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http://dx.doi.org/10.1016/j.jpba.2016.03.009DOI Listing
May 2016

Pyridine-grafted chitosan derivative as an antifungal agent.

Food Chem 2016 Apr 16;196:381-7. Epub 2015 Sep 16.

Key Laboratory of Fruits and Vegetables Postharvest and Processing Technology Research of Zhejiang Province, College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2015.09.053DOI Listing
April 2016

Computed tomography morphometric analysis of anterior instrumentation in the pediatric thoracic spine.

J Neurosurg Pediatr 2016 Apr 11;17(4):504-9. Epub 2015 Dec 11.

Department of Orthopaedic Surgery, Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

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http://dx.doi.org/10.3171/2015.6.PEDS14523DOI Listing
April 2016

Stabilization of HIF-1α by FG-4592 promotes functional recovery and neural protection in experimental spinal cord injury.

Brain Res 2016 Feb 17;1632:19-26. Epub 2015 Dec 17.

Department of Orthopaedics, The Second affiliated hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China; Zhejiang Provincial Key laboratory of orthopaedics, Wenzhou, Zhejiang Province, China. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2015.12.017DOI Listing
February 2016

Silver/chitosan-based Janus particles: Synthesis, characterization, and assessment of antimicrobial activity in vivo and vitro.

Food Res Int 2015 Dec 1;78:433-441. Epub 2015 Sep 1.

Key Laboratory of Fruits and Vegetables Postharvest and Processing Technology Research of Zhejiang Province, College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09639969153016
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http://dx.doi.org/10.1016/j.foodres.2015.08.035DOI Listing
December 2015

Simultaneous determination of ascaridole, p-cymene and α-terpinene in rat plasma after oral administration of Chenopodium ambrosioides L. by GC-MS.

Biomed Chromatogr 2015 Nov 21;29(11):1682-6. Epub 2015 Apr 21.

Tasly Academy, Tasly Holding Group Co. Ltd, Tianjin, 300410, China.

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http://doi.wiley.com/10.1002/bmc.3479
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November 2015

Classification of MRI under the Presence of Disease Heterogeneity using Multi-Task Learning: Application to Bipolar Disorder.

Med Image Comput Comput Assist Interv 2015 Oct 18;9349:125-132. Epub 2015 Nov 18.

Center for Biomedical Image Computing and Analytics, and Department of Radiology, University of Pennsylvania, Philadelphia PA 19104, United States.

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http://dx.doi.org/10.1007/978-3-319-24553-9_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777522PMC
October 2015

Identification of a major metabolite of danshensu in rat urine and simultaneous determination of danshensu and its metabolite in plasma: application to a pharmacokinetic study in rats.

Drug Test Anal 2015 Aug 29;7(8):727-36. Epub 2014 Dec 29.

Tianjin State key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin, 300193, China.

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http://dx.doi.org/10.1002/dta.1750DOI Listing
August 2015

Adsorption equilibrium and kinetics of monomer-dimer monoclonal antibody mixtures on a cation exchange resin.

J Chromatogr A 2015 Jul 23;1402:46-59. Epub 2015 May 23.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2015.05.007DOI Listing
July 2015

Simultaneous determination of caffeic acid and its major pharmacologically active metabolites in rat plasma by LC-MS/MS and its application in pharmacokinetic study.

Biomed Chromatogr 2015 Apr 27;29(4):552-9. Epub 2014 Aug 27.

Tasly R&D Institute, Tianjin Tasly Group Co. Ltd, Tianjin, 300410, People's Republic of China.

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http://dx.doi.org/10.1002/bmc.3313DOI Listing
April 2015

Engineering of novel Staphylococcal Protein A ligands to enable milder elution pH and high dynamic binding capacity.

J Chromatogr A 2014 Oct 19;1362:180-5. Epub 2014 Aug 19.

MedImmune, Purification Process Sciences, One MedImmune Way, Gaithersburg, MD 20878, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2014.08.046DOI Listing
October 2014

Effect of chitosan and its derivatives as antifungal and preservative agents on postharvest green asparagus.

Food Chem 2014 Jul 23;155:105-11. Epub 2014 Jan 23.

Key Laboratory of Fruits and Vegetables Postharvest and Processing Technology Research of Zhejiang Province, College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2014.01.026DOI Listing
July 2014

Lactate down-regulates matrix systhesis and promotes apoptosis and autophagy in rat nucleus pulposus cells.

J Orthop Res 2014 Feb 25;32(2):253-61. Epub 2013 Oct 25.

Department of Orthopaedics, The Second Affiliated Hospital of Wenzhou Medical University, 109 Western Xueyuan Road, Wenzhou, China.

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http://doi.wiley.com/10.1002/jor.22503
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February 2014

Enhanced catalysis of oxime-based bioconjugations by substituted anilines.

Bioconjug Chem 2014 Jan 17;25(1):93-101. Epub 2013 Dec 17.

Department of Purification Process Sciences and ‡Department of Antibody Discovery and Protein Engineering, MedImmune, LLC , Gaithersburg, Maryland 20878, United States.

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http://dx.doi.org/10.1021/bc400380fDOI Listing
January 2014

Process-scale purification and analytical characterization of highly gamma-carboxylated recombinant human prothrombin.

J Chromatogr A 2014 Jan 15;1325:171-8. Epub 2013 Dec 15.

MedImmune LLC, Department of Purification Process Sciences, One MedImmune Way, Gaithersburg, MD 20878, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2013.12.024DOI Listing
January 2014

Label-free fluorescent DNA biosensors based on metallointercalators and nanomaterials.

Methods 2013 Dec 15;64(3):305-14. Epub 2013 Jul 15.

Department of Chemistry, Tongji University, Shanghai 200092, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2013.07.004DOI Listing
December 2013

Codon optimisation improves the expression of Trichoderma viride sp. endochitinase in Pichia pastoris.

Sci Rep 2013 Oct 24;3:3043. Epub 2013 Oct 24.

College of Food Science and Biotechnology, Zhejiang Gongshang University, 149 Jiaogong Road, Hangzhou 310035, Zhejiang Province, People's Republic of China.

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http://dx.doi.org/10.1038/srep03043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807108PMC
October 2013

Collecting duct carcinoma of the kidney: a clinicopathological study of five cases.

Diagn Pathol 2013 Jun 17;8:96. Epub 2013 Jun 17.

Department of Urology, Henan Provincial People's Hospital, Zhengzhou 450003, China.

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http://dx.doi.org/10.1186/1746-1596-8-96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728027PMC
June 2013

Apoptosis, senescence, and autophagy in rat nucleus pulposus cells: Implications for diabetic intervertebral disc degeneration.

J Orthop Res 2013 May 13;31(5):692-702. Epub 2012 Dec 13.

Department of Orthopaedics, The Second Affiliated Hospital of Wenzhou Medical College, 109 Western Xueyuan Road, Wenzhou, China.

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http://dx.doi.org/10.1002/jor.22289DOI Listing
May 2013

Mesogastrium: a fifth route of metastasis in gastric cancer?

Med Hypotheses 2013 Apr 10;80(4):498-500. Epub 2013 Feb 10.

Department of Gastrointestinal Surgery, Tongji Cancer Research Institute, Tongji Hospital, Tongji Medical College in Huazhong University of Science and Technology, Wuhan 430030, PR China.

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http://linkinghub.elsevier.com/retrieve/pii/S030698771200569
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http://dx.doi.org/10.1016/j.mehy.2012.12.020DOI Listing
April 2013

Effect of chitosan coatings on postharvest green asparagus quality.

Carbohydr Polym 2013 Feb 1;92(2):2027-32. Epub 2012 Dec 1.

College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, PR China.

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http://dx.doi.org/10.1016/j.carbpol.2012.11.070DOI Listing
February 2013

Evaluation antibacterial activity of quaternary-based chitin/chitosan derivatives in vitro.

J Food Sci 2013 Jan;78(1):M90-7

College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, PR China.

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http://dx.doi.org/10.1111/j.1750-3841.2012.02999.xDOI Listing
January 2013