Publications by authors named "Xiangfeng Lu"

84Publications

The 17-y spatiotemporal trend of PM and its mortality burden in China.

Proc Natl Acad Sci U S A 2020 Oct 21;117(41):25601-25608. Epub 2020 Sep 21.

Key Laboratory of Cardiovascular Epidemiology, Chinese Academy of Medical Sciences, Beijing 100037, China;

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http://dx.doi.org/10.1073/pnas.1919641117DOI Listing
October 2020

Ambient air pollution and body weight status in adults: A systematic review and meta-analysis.

Environ Pollut 2020 Oct 13;265(Pt A):114999. Epub 2020 Jun 13.

Key Laboratory of Cardiovascular Epidemiology, Chinese Academy of Medical Sciences, Beijing 100037, China; Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China; School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.

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http://dx.doi.org/10.1016/j.envpol.2020.114999DOI Listing
October 2020

Long-Term Effects of High Exposure to Ambient Fine Particulate Matter on Coronary Heart Disease Incidence: A Population-Based Chinese Cohort Study.

Environ Sci Technol 2020 06 15;54(11):6812-6821. Epub 2020 May 15.

Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, P. R. China.

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http://dx.doi.org/10.1021/acs.est.9b06663DOI Listing
June 2020

Associations of egg consumption with incident cardiovascular disease and all-cause mortality.

Sci China Life Sci 2020 Sep 10;63(9):1-11. Epub 2020 Mar 10.

Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.

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http://dx.doi.org/10.1007/s11427-020-1656-8DOI Listing
September 2020

Associations of long-term exposure to ambient PM with mortality in Chinese adults: A pooled analysis of cohorts in the China-PAR project.

Environ Int 2020 May 5;138:105589. Epub 2020 Mar 5.

Key Laboratory of Cardiovascular Epidemiology, Chinese Academy of Medical Sciences; Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China; Medical School, Southern University of Science and Technology, Shenzhen 518055, China. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2020.105589DOI Listing
May 2020

Long-Term Exposure to Fine Particulate Matter and Cardiovascular Disease in China.

J Am Coll Cardiol 2020 02;75(7):707-717

Key Laboratory of Cardiovascular Epidemiology, Chinese Academy of Medical Sciences, Beijing, China; Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Medical School, Southern University of Science and Technology, Shenzhen, China. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2019.12.031DOI Listing
February 2020

Tea consumption and the risk of atherosclerotic cardiovascular disease and all-cause mortality: The China-PAR project.

Eur J Prev Cardiol 2020 Jan 8:2047487319894685. Epub 2020 Jan 8.

Key Laboratory of Cardiovascular Epidemiology and Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, China.

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http://dx.doi.org/10.1177/2047487319894685DOI Listing
January 2020

Long term exposure to ambient fine particulate matter and incidence of stroke: prospective cohort study from the China-PAR project.

BMJ 2019 12 30;367:l6720. Epub 2019 Dec 30.

Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Xicheng District, Beijing 100037, China

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http://dx.doi.org/10.1136/bmj.l6720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190010PMC
December 2019

Association of Lipids With Ischemic and Hemorrhagic Stroke: A Prospective Cohort Study Among 267 500 Chinese.

Stroke 2019 12 29;50(12):3376-3384. Epub 2019 Oct 29.

From the Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (X.G., Yunzhi Li, X.Y., F.L., Ying Li, J.L., J. Cao, J. Chen, J.H., X. Lu, D.G.).

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http://dx.doi.org/10.1161/STROKEAHA.119.026402DOI Listing
December 2019

Predicting 10-Year and Lifetime Stroke Risk in Chinese Population.

Stroke 2019 09 8;50(9):2371-2378. Epub 2019 Aug 8.

From the Department of Epidemiology, Key Laboratory of Cardiovascular Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (X.X., X.Y., F. Liu, J.L., J. Cao, J. Chen, L.Z., Y.L., X. Lu, D.G.).

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http://dx.doi.org/10.1161/STROKEAHA.119.025553DOI Listing
September 2019

Interactive Mobile Health Intervention and Blood Pressure Management in Adults.

Hypertension 2019 09 22;74(3):697-704. Epub 2019 Jul 22.

From the Key Laboratory of Cardiovascular Epidemiology and Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Xiaomei Lu, H.Y., X.X., Xiangfeng Lu, J.L., F.L., .D.G.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13273DOI Listing
September 2019

Identification of circular RNA Hsa_circ_0001879 and Hsa_circ_0004104 as novel biomarkers for coronary artery disease.

Atherosclerosis 2019 07 9;286:88-96. Epub 2019 May 9.

Key Laboratory of Cardiovascular Epidemiology & Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.05.006DOI Listing
July 2019

Long-Term Exposure to Fine Particulate Matter and Hypertension Incidence in China.

Hypertension 2019 06;73(6):1195-1201

From the Department of Epidemiology, Key Laboratory of Cardiovascular Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (K.H., X.Y., F. Liang, F. Liu, J.L., J. Chen, J. Cao, L.Z., Xigui Wu, Y. Li, J.H., X. Lu, D.G.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.12666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656583PMC
June 2019

LncRNA ENST00000602558.1 regulates ABCG1 expression and cholesterol efflux from vascular smooth muscle cells through a p65-dependent pathway.

Atherosclerosis 2019 06 8;285:31-39. Epub 2019 Apr 8.

Key Laboratory of Cardiovascular Epidemiology & Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing 100037, China.

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.04.204DOI Listing
June 2019

Lifetime Risk of Stroke in the Global Burden of Disease Study.

N Engl J Med 2019 04;380(14):1377

Chinese Academy of Medical Sciences, Beijing, China

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http://dx.doi.org/10.1056/NEJMc1900607DOI Listing
April 2019

Long-term exposure to ambient fine particulate matter and incidence of diabetes in China: A cohort study.

Environ Int 2019 05 7;126:568-575. Epub 2019 Mar 7.

Key Laboratory of Cardiovascular Epidemiology & Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

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http://dx.doi.org/10.1016/j.envint.2019.02.069DOI Listing
May 2019

Impact of healthy lifestyles on cancer risk in the Chinese population.

Cancer 2019 06 12;125(12):2099-2106. Epub 2019 Feb 12.

Key Laboratory of Cardiovascular Epidemiology & Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1002/cncr.31971DOI Listing
June 2019

Association of Kir genes with blood pressure responses to dietary sodium intervention: the GenSalt study.

Hypertens Res 2018 Dec 15;41(12):1045-1053. Epub 2018 Oct 15.

Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1038/s41440-018-0113-6DOI Listing
December 2018

Genetic variants of cGMP-dependent protein kinase genes and salt sensitivity of blood pressure: the GenSalt study.

J Hum Hypertens 2019 01 4;33(1):62-68. Epub 2018 Sep 4.

Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1038/s41371-018-0099-1DOI Listing
January 2019

Ideal cardiovascular health and incidence of atherosclerotic cardiovascular disease among Chinese adults: the China-PAR project.

Sci China Life Sci 2018 05 19;61(5):504-514. Epub 2018 Mar 19.

Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.

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http://dx.doi.org/10.1007/s11427-018-9281-6DOI Listing
May 2018

Genome-Wide Association and Functional Studies Identify and as Novel Susceptibility Genes for Coronary Artery Disease.

Arterioscler Thromb Vasc Biol 2018 04 22;38(4):964-975. Epub 2018 Feb 22.

From the Department of Human Population Genetics, Institute of Molecular Medicine, Peking University, Beijing, China (Y.L., J.G., K.X., C.S., F.Y., B.Z., H.Y., W.-J.W., C.W., J.D., G.Z., X.-L.T.); Beijing Anzhen Hospital (Y.L.), Department of Cardiology, Beijing Anzhen Hospital (Y.Y., C.W.), and Department of Cardiology, Beijing Chaoyang Hospital (F.J.), Capital Medical University, China; Beijing Institute of Heart, Lung, and Blood Vessel Disease, China (Y.L.); Department of Internal Medicine, Gene Therapy Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (D.W.W., H.D., S.T.); Department of Cardiology, The General Hospital of Chinese People's Liberation Army, Beijing, China (Y.C., Z.S.); Cardiovascular Medicine Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China (C.C., S.H., J.Z., Y.M., W.C., J.S., W.L.); State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing (S.Z., X.L., X.Y., D.G.); Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, China (L.Z.); Department of Internal Medicine, Hospital of Peking University, Beijing, China (Y.C.); Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, China (L.J.); Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, China (G.L.); Cardiovascular Department, Ningbo First Hospital, Ningbo University, China (H.C., S.W.); Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Germany (J.E.); German Research Centre for Cardiovascular Research, Partner Site Hamburg/Lübeck/Kiel (J.E.); Deutsches Herzzentrum München, Technische Universität München, Germany (L.Z., H.S.); German Centre for Cardiovascular Research, Partner Site Munich Heart Alliance (L.Z., H.S.); Department of Human Population Genetics, Human Aging Research Institute and School of Life Science, Nanchang University, China (S.C., X.-L.T.); and Institute of Medical Systems Biology (S.R.) and School of Public Health (S.R.), Guangdong Medical University, Dongguan, China.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.117.310594
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http://dx.doi.org/10.1161/ATVBAHA.117.310594DOI Listing
April 2018

Exome-wide association study of plasma lipids in >300,000 individuals.

Authors:
Dajiang J Liu Gina M Peloso Haojie Yu Adam S Butterworth Xiao Wang Anubha Mahajan Danish Saleheen Connor Emdin Dewan Alam Alexessander Couto Alves Philippe Amouyel Emanuele Di Angelantonio Dominique Arveiler Themistocles L Assimes Paul L Auer Usman Baber Christie M Ballantyne Lia E Bang Marianne Benn Joshua C Bis Michael Boehnke Eric Boerwinkle Jette Bork-Jensen Erwin P Bottinger Ivan Brandslund Morris Brown Fabio Busonero Mark J Caulfield John C Chambers Daniel I Chasman Y Eugene Chen Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu John M Connell Francesco Cucca L Adrienne Cupples Scott M Damrauer Gail Davies Ian J Deary George Dedoussis Joshua C Denny Anna Dominiczak Marie-Pierre Dubé Tapani Ebeling Gudny Eiriksdottir Tõnu Esko Aliki-Eleni Farmaki Mary F Feitosa Marco Ferrario Jean Ferrieres Ian Ford Myriam Fornage Paul W Franks Timothy M Frayling Ruth Frikke-Schmidt Lars G Fritsche Philippe Frossard Valentin Fuster Santhi K Ganesh Wei Gao Melissa E Garcia Christian Gieger Franco Giulianini Mark O Goodarzi Harald Grallert Niels Grarup Leif Groop Megan L Grove Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Joel N Hirschhorn Oddgeir L Holmen Jennifer Huffman Yong Huo Kristian Hveem Sehrish Jabeen Anne U Jackson Johanna Jakobsdottir Marjo-Riitta Jarvelin Gorm B Jensen Marit E Jørgensen J Wouter Jukema Johanne M Justesen Pia R Kamstrup Stavroula Kanoni Fredrik Karpe Frank Kee Amit V Khera Derek Klarin Heikki A Koistinen Jaspal S Kooner Charles Kooperberg Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo Lakka Claudia Langenberg Anne Langsted Lenore J Launer Torsten Lauritzen David C M Liewald Li An Lin Allan Linneberg Ruth J F Loos Yingchang Lu Xiangfeng Lu Reedik Mägi Anders Malarstig Ani Manichaikul Alisa K Manning Pekka Mäntyselkä Eirini Marouli Nicholas G D Masca Andrea Maschio James B Meigs Olle Melander Andres Metspalu Andrew P Morris Alanna C Morrison Antonella Mulas Martina Müller-Nurasyid Patricia B Munroe Matt J Neville Jonas B Nielsen Sune F Nielsen Børge G Nordestgaard Jose M Ordovas Roxana Mehran Christoper J O'Donnell Marju Orho-Melander Cliona M Molony Pieter Muntendam Sandosh Padmanabhan Colin N A Palmer Dorota Pasko Aniruddh P Patel Oluf Pedersen Markus Perola Annette Peters Charlotta Pisinger Giorgio Pistis Ozren Polasek Neil Poulter Bruce M Psaty Daniel J Rader Asif Rasheed Rainer Rauramaa Dermot F Reilly Alex P Reiner Frida Renström Stephen S Rich Paul M Ridker John D Rioux Neil R Robertson Dan M Roden Jerome I Rotter Igor Rudan Veikko Salomaa Nilesh J Samani Serena Sanna Naveed Sattar Ellen M Schmidt Robert A Scott Peter Sever Raquel S Sevilla Christian M Shaffer Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Albert V Smith Blair H Smith Sangeetha Somayajula Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kathleen E Stirrups Nathan Stitziel Konstantin Strauch Heather M Stringham Praveen Surendran Hayato Tada Alan R Tall Hua Tang Jean-Claude Tardif Kent D Taylor Stella Trompet Philip S Tsao Jaakko Tuomilehto Anne Tybjaerg-Hansen Natalie R van Zuydam Anette Varbo Tibor V Varga Jarmo Virtamo Melanie Waldenberger Nan Wang Nick J Wareham Helen R Warren Peter E Weeke Joshua Weinstock Jennifer Wessel James G Wilson Peter W F Wilson Ming Xu Hanieh Yaghootkar Robin Young Eleftheria Zeggini He Zhang Neil S Zheng Weihua Zhang Yan Zhang Wei Zhou Yanhua Zhou Magdalena Zoledziewska Joanna M M Howson John Danesh Mark I McCarthy Chad A Cowan Goncalo Abecasis Panos Deloukas Kiran Musunuru Cristen J Willer Sekar Kathiresan

Nat Genet 2017 Dec 30;49(12):1758-1766. Epub 2017 Oct 30.

Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709146PMC
December 2017

Blood Pressure Genetic Risk Score Predicts Blood Pressure Responses to Dietary Sodium and Potassium: The GenSalt Study (Genetic Epidemiology Network of Salt Sensitivity).

Hypertension 2017 12 9;70(6):1106-1112. Epub 2017 Oct 9.

From the Department of Epidemiology (J.L.N., C.L., J.H., T.N.K.) and Department of Medicine (J.H.), Tulane University School of Public Health and Tropical Medicine, New Orleans, LA; Department of Epidemiology and Biostatistics, University of Georgia College of Public Health, Athens (C.L.); Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (D.G., J.C., X.L., J.L., X.W.); Department of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, Houston (J.E.H.); and Division of Biostatistics, Washington University School of Medicine, St. Louis, MO (C.C.G., D.C.R.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443381PMC
December 2017

Associations Between Genetic Variants of NADPH Oxidase-Related Genes and Blood Pressure Responses to Dietary Sodium Intervention: The GenSalt Study.

Am J Hypertens 2017 Apr;30(4):427-434

Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1093/ajh/hpw200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191854PMC
April 2017

Coding-sequence variants are associated with blood lipid levels in 14,473 Chinese.

Hum Mol Genet 2016 09 11;25(18):4107-4116. Epub 2016 Aug 11.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China

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http://dx.doi.org/10.1093/hmg/ddw261DOI Listing
September 2016

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.

Authors:
Majid Nikpay Anuj Goel Hong-Hee Won Leanne M Hall Christina Willenborg Stavroula Kanoni Danish Saleheen Theodosios Kyriakou Christopher P Nelson Jemma C Hopewell Thomas R Webb Lingyao Zeng Abbas Dehghan Maris Alver Sebastian M Armasu Kirsi Auro Andrew Bjonnes Daniel I Chasman Shufeng Chen Ian Ford Nora Franceschini Christian Gieger Christopher Grace Stefan Gustafsson Jie Huang Shih-Jen Hwang Yun Kyoung Kim Marcus E Kleber King Wai Lau Xiangfeng Lu Yingchang Lu Leo-Pekka Lyytikäinen Evelin Mihailov Alanna C Morrison Natalia Pervjakova Liming Qu Lynda M Rose Elias Salfati Richa Saxena Markus Scholz Albert V Smith Emmi Tikkanen Andre Uitterlinden Xueli Yang Weihua Zhang Wei Zhao Mariza de Andrade Paul S de Vries Natalie R van Zuydam Sonia S Anand Lars Bertram Frank Beutner George Dedoussis Philippe Frossard Dominique Gauguier Alison H Goodall Omri Gottesman Marc Haber Bok-Ghee Han Jianfeng Huang Shapour Jalilzadeh Thorsten Kessler Inke R König Lars Lannfelt Wolfgang Lieb Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Patrik K Magnusson Nadeem H Mallick Narinder Mehra Thomas Meitinger Fazal-Ur-Rehman Memon Andrew P Morris Markku S Nieminen Nancy L Pedersen Annette Peters Loukianos S Rallidis Asif Rasheed Maria Samuel Svati H Shah Juha Sinisalo Kathleen E Stirrups Stella Trompet Laiyuan Wang Khan S Zaman Diego Ardissino Eric Boerwinkle Ingrid B Borecki Erwin P Bottinger Julie E Buring John C Chambers Rory Collins L Adrienne Cupples John Danesh Ilja Demuth Roberto Elosua Stephen E Epstein Tõnu Esko Mary F Feitosa Oscar H Franco Maria Grazia Franzosi Christopher B Granger Dongfeng Gu Vilmundur Gudnason Alistair S Hall Anders Hamsten Tamara B Harris Stanley L Hazen Christian Hengstenberg Albert Hofman Erik Ingelsson Carlos Iribarren J Wouter Jukema Pekka J Karhunen Bong-Jo Kim Jaspal S Kooner Iftikhar J Kullo Terho Lehtimäki Ruth J F Loos Olle Melander Andres Metspalu Winfried März Colin N Palmer Markus Perola Thomas Quertermous Daniel J Rader Paul M Ridker Samuli Ripatti Robert Roberts Veikko Salomaa Dharambir K Sanghera Stephen M Schwartz Udo Seedorf Alexandre F Stewart David J Stott Joachim Thiery Pierre A Zalloua Christopher J O'Donnell Muredach P Reilly Themistocles L Assimes John R Thompson Jeanette Erdmann Robert Clarke Hugh Watkins Sekar Kathiresan Ruth McPherson Panos Deloukas Heribert Schunkert Nilesh J Samani Martin Farrall

Nat Genet 2015 Oct 7;47(10):1121-1130. Epub 2015 Sep 7.

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.3396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589895PMC
October 2015

Genetic predisposition to higher blood pressure increases risk of incident hypertension and cardiovascular diseases in Chinese.

Hypertension 2015 Oct 17;66(4):786-92. Epub 2015 Aug 17.

From the State Key Laboratory of Cardiovascular Disease (X.L., L.W., S.C., X.Y., J.L., J. Cao, J. Chen, Y.L., L.Z., F.L., C.H., D. Gu) and Hypertension Division (J.H.), Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; National Human Genome Center at Beijing, Beijing, China (L.W., H.L.); Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China (C.S.); Yancheng Municipal Center for Disease Control and Prevention, Yancheng, Jiangsu, China (J.S.); Department of Cardiology, Fujian Provincial People's Hospital, Fuzhou, Fujian, China (L.Y.); Department of Cardiology, the Affiliated Hospital of Beihua University, Beihua University, Jilin, China (L.X.); Department of Cardiology, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, Shannxi, China (J.M.); Center for Chronic and Noncommunicable Disease Control and Prevention, Sichuan Center of Disease Control and Prevention, Chengdu, Sichuan, China (X.W.); Department of Internal Medicine, Xinle Red Cross Hospital, Xinle, Hebei, China (X.J.); Department of Internal Medicine, Yuxian Renmin Hospital, Yuxian, Shanxi, China (D. Guo); Changshu Center of Disease Control and Prevention, Changshu, Jiangsu, China (Z.Z.); Nantong Center of Disease Control and Prevention, Nantong, Jiangsu, China (Z.Y.); Department of Internal Medicine, Shijiazhuang Greatwall Hospital, Shijiazhuang, Hebei, China (R.W.); Department of Cardiology, Hanzhong People's Hospital, Hanzhong, Shannxi, China (J.Y.); and Department of Clinical Epidemiology, Children's Hospital of Fudan University, Shanghai, China (W.Y.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05961DOI Listing
October 2015

Associations Between Genetic Variants of the Natriuretic Peptide System and Blood Pressure Response to Dietary Sodium Intervention: The GenSalt Study.

Am J Hypertens 2016 Mar 29;29(3):397-404. Epub 2015 Jul 29.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;

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http://dx.doi.org/10.1093/ajh/hpv129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757957PMC
March 2016

Plasma miR-122 and miR-3149 Potentially Novel Biomarkers for Acute Coronary Syndrome.

PLoS One 2015 1;10(5):e0125430. Epub 2015 May 1.

Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125430PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416808PMC
February 2016

INMAP overexpression inhibits cell proliferation, induces genomic instability and functions through p53/p21 pathways.

PLoS One 2015 30;10(1):e0115704. Epub 2015 Jan 30.

Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, 100875, P. R. China; Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education, College of Life Sciences, Beijing Normal University, Beijing, 100875, P. R. China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115704PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312054PMC
October 2015

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.

Hum Mol Genet 2015 Mar 26;24(6):1791-800. Epub 2014 Nov 26.

Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA.

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http://hmg.oxfordjournals.org/content/24/6/1791.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddu583
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http://dx.doi.org/10.1093/hmg/ddu583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351379PMC
March 2015

The prognostic significance of atrial fibrillation in heart failure with a preserved and reduced left ventricular function: insights from a meta-analysis.

Eur J Heart Fail 2014 Dec 5;16(12):1317-22. Epub 2014 Nov 5.

State Key Laboratory of Cardiovascular Disease, Department of Evidence Based Medicine, Fuwai Hospital, National Centre for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beili Shi Road 167, Beijing, China.

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http://dx.doi.org/10.1002/ejhf.187DOI Listing
December 2014

Association between the SIRT1 mRNA expression and acute coronary syndrome.

J Atheroscler Thromb 2015 23;22(2):165-82. Epub 2014 Oct 23.

State Key Laboratory of Cardiovascular Disease, Division of Population Genetics, Fuwai Hospital & National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; National Human Genome Center at Beijing, Beijing, China.

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http://dx.doi.org/10.5551/jat.24844DOI Listing
December 2015

Electrocardiographic PR prolongation and atrial fibrillation risk: a meta-analysis of prospective cohort studies.

J Cardiovasc Electrophysiol 2015 Jan 26;26(1):36-41. Epub 2014 Sep 26.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://doi.wiley.com/10.1111/jce.12539
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http://dx.doi.org/10.1111/jce.12539DOI Listing
January 2015

Functional analysis of single-nucleotide polymorphisms in the regulation of coactivator-associated arginine methyltransferase 1 expression and plasma homocysteine levels.

Circ Cardiovasc Genet 2014 Oct 26;7(5):642-9. Epub 2014 Jul 26.

From the State Key Laboratory of Cardiovascular Disease, Division of Population Genetics, Fuwai Hospital and National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (X. Liu, Y.H., L.W., H.L., X. Lu, J.C., Y.H., X.M., D.G.); State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (X.P.); and Department of Cardiovascular Genetics, National Human Genome Center at Beijing, Beijing, China (X. Liu).

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October 2014

Common variants in TGFBR2 and miR-518 genes are associated with hypertension in the Chinese population.

Am J Hypertens 2014 Oct 31;27(10):1268-76. Epub 2014 Mar 31.

Department of Cardiology, Affiliated Yixing People's Hospital of Jiangsu University, People's Hospital of Yixing City, Yixing, China;

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http://dx.doi.org/10.1093/ajh/hpu047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815702PMC
October 2014

Caffeine intake and atrial fibrillation incidence: dose response meta-analysis of prospective cohort studies.

Can J Cardiol 2014 Apr 2;30(4):448-54. Epub 2014 Jan 2.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2013.12.026DOI Listing
April 2014

Coactivator-associated arginine methyltransferase 1 targeted by miR-15a regulates inflammation in acute coronary syndrome.

Atherosclerosis 2014 Apr 30;233(2):349-356. Epub 2014 Jan 30.

State Key Laboratory of Cardiovascular Disease, Division of Population Genetics, Fuwai Hospital & National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.01.039DOI Listing
April 2014

Association study of common variations of FBN1 gene and essential hypertension in Han Chinese population.

Mol Biol Rep 2014 12;41(4):2257-64. Epub 2014 Jan 12.

Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 210029, China.

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http://dx.doi.org/10.1007/s11033-014-3078-9DOI Listing
December 2014

Lipoprotein lipase gene polymorphism rs1059611 functionally influences serum lipid concentrations.

Atherosclerosis 2013 Aug 18;229(2):511-6. Epub 2013 May 18.

State Key Laboratory of Cardiovascular Disease, Division of Population Genetics, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing 100037, China.

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http://dx.doi.org/10.1016/j.atherosclerosis.2013.05.005DOI Listing
August 2013

Genome-wide association study in Han Chinese identifies three novel loci for human height.

Hum Genet 2013 Jun 3;132(6):681-9. Epub 2013 Mar 3.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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June 2013

Association of lipoprotein lipase polymorphism rs2197089 with serum lipid concentrations and LPL gene expression.

J Hum Genet 2013 Mar 24;58(3):160-4. Epub 2013 Jan 24.

State Key Laboratory of Cardiovascular Disease, Division of Population Genetics, Fuwai Hospital & National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

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http://www.nature.com/articles/jhg2012151
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March 2013

[Cloning and characterization of a thermostable urate oxidase from Microbacterium sp. strain ZZJ4-1].

Sheng Wu Gong Cheng Xue Bao 2012 Jul;28(7):813-22

College of Life Sciences, Zhejiang University, Hangzhou 310058, Zhejiang, China.

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July 2012

Adiponectin levels and risk of coronary heart disease: a meta-analysis of prospective studies.

Am J Med Sci 2013 Jun;345(6):455-61

State Key Laboratory of Cardiovascular Disease, Department of Evidence Based Medicine, Fu Wai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences, Beijing, China.

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June 2013

Association of adrenomedullin gene polymorphisms and blood pressure in a Chinese population.

Hypertens Res 2013 Jan 30;36(1):74-8. Epub 2012 Aug 30.

State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Division of Population Genetics, Department of Evidence Based Medicine, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1038/hr.2012.132DOI Listing
January 2013

[Cloning, expression and characterization of a gamma-butyrobetaine hydroxylase gene bbh from Pseudomonas sp. L-1].

Wei Sheng Wu Xue Bao 2012 May;52(5):602-10

Institute of Microbiology, College of Life Science, Zhejiang University, Hangzhou 310058, China.

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May 2012

Polymorphisms of ACE2 are associated with blood pressure response to cold pressor test: the GenSalt study.

Am J Hypertens 2012 Aug 31;25(8):937-42. Epub 2012 May 31.

Department of Evidence Based Medicine and Division of Population Genetics, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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August 2012

Association between genetic variants of the ADD1 and GNB3 genes and blood pressure response to the cold pressor test in a Chinese Han population: the GenSalt Study.

Hypertens Res 2012 Aug 5;35(8):805-10. Epub 2012 Apr 5.

Department of Evidence Based Medicine and Division of Population Genetics, State Key Laboratory of Cardiovascular Disease, Cardiovascular Institute and Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1038/hr.2012.38DOI Listing
August 2012

Effect of omega-3 fatty acids supplementation on endothelial function: a meta-analysis of randomized controlled trials.

Atherosclerosis 2012 Apr 20;221(2):536-43. Epub 2012 Jan 20.

State Key Laboratory of Cardiovascular Disease, Department of Evidence Based Medicine, Fuwai Hospital & National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

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http://linkinghub.elsevier.com/retrieve/pii/S002191501200010
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http://dx.doi.org/10.1016/j.atherosclerosis.2012.01.006DOI Listing
April 2012

Association between polymorphisms in the coagulation factor VII gene and coronary heart disease risk in different ethnicities: a meta-analysis.

BMC Med Genet 2011 Aug 12;12:107. Epub 2011 Aug 12.

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1186/1471-2350-12-107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166910PMC
August 2011

Classical risk factors of cardiovascular disease among Chinese male steel workers: a prospective cohort study for 20 years.

BMC Public Health 2011 Jun 25;11:497. Epub 2011 Jun 25.

Department of Evidence Based Medicine, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1186/1471-2458-11-497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141460PMC
June 2011

Novel genetic variation in exon 28 of FBN1 gene is associated with essential hypertension.

Am J Hypertens 2011 Jun 17;24(6):687-93. Epub 2011 Feb 17.

Division of Population Genetics, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.

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http://ajh.oxfordjournals.org/cgi/doi/10.1038/ajh.2011.21
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June 2011

Association of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) gene polymorphisms and type 2 diabetes mellitus: a meta-analysis.

Diabetes Metab Res Rev 2011 Feb;27(2):177-84

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1002/dmrr.1158DOI Listing
February 2011

PLA2G7 gene polymorphisms and coronary heart disease risk: a meta-analysis.

Thromb Res 2010 Dec;126(6):498-503

Department of Evidence BasedMedicine and Division of Population Genetics, Cardiovascular Institute and FuWai Hospital, Chinese Academy ofMedical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1016/j.thromres.2010.09.009DOI Listing
December 2010

Genetic variants in the renin-angiotensin system and blood pressure reactions to the cold pressor test.

J Hypertens 2010 Dec;28(12):2422-8

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1097/HJH.0b013e32833ea74eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029492PMC
December 2010

Heart rate influence on incidence of cardiovascular disease among adults in China.

Int J Epidemiol 2010 Dec 17;39(6):1638-46. Epub 2010 Aug 17.

Department of Evidence Based Medicine, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1093/ije/dyq119DOI Listing
December 2010

[Purification and characterization of a sarcosine oxidase from Bacillus sp. BSD-8].

Sheng Wu Gong Cheng Xue Bao 2010 Mar;26(3):335-40

College of Life Sciences, Zhejiang University, Hangzhou 310058, China.

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March 2010

Polymorphisms in the GNB3 and ADD1 genes and blood pressure in a Chinese population.

Hum Genet 2010 Aug 16;128(2):137-43. Epub 2010 May 16.

Division of Population Genetics, Department of Evidence Based Medicine, Cardiovascular Institute, Fu Wai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, 167 Beilishi Road, Beijing, 100037, China.

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http://dx.doi.org/10.1007/s00439-010-0834-3DOI Listing
August 2010

Emilin1 gene and essential hypertension: a two-stage association study in northern Han Chinese population.

BMC Med Genet 2009 Nov 18;10:118. Epub 2009 Nov 18.

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College P eople's Republic of China, No, 167 Beilishi Rd, Beijing 100037, PR China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785781PMC
November 2009

Association of an intronic variant of the heme oxygenase-1 gene with hypertension in northern Chinese Han population.

Clin Exp Hypertens 2009 Oct;31(7):534-43

Department of Evidence-Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, PR China.

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http://dx.doi.org/10.3109/10641960902825461DOI Listing
October 2009

Interactions among genetic variants from SREBP2 activating-related pathway on risk of coronary heart disease in Chinese Han population.

Atherosclerosis 2010 Feb 14;208(2):421-6. Epub 2009 Aug 14.

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fu Wai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China.

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http://dx.doi.org/10.1016/j.atherosclerosis.2009.08.011DOI Listing
February 2010

Functional analysis of the C-reactive protein (CRP) gene -717A>G polymorphism associated with coronary heart disease.

BMC Med Genet 2009 Jul 22;10:73. Epub 2009 Jul 22.

Department of Evidence Based Medicine & Division of Population Genetics, Fu Wai Hospital & Cardiovascular Institute, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China.

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http://dx.doi.org/10.1186/1471-2350-10-73DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723087PMC
July 2009

Haplotype analysis of the stromelysin-1 (MMP3) and gelatinase B (MMP9) genes in relation to coronary heart disease.

Ann Hum Genet 2009 Jul 11;73(Pt 4):404-10. Epub 2009 May 11.

Department of Cardiology, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Beijing, China.

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http://dx.doi.org/10.1111/j.1469-1809.2009.00522.xDOI Listing
July 2009

Polymorphisms of MMP-2 gene are associated with systolic heart failure prognosis.

Clin Chim Acta 2009 Jun 28;404(2):119-23. Epub 2009 Mar 28.

Department of Cardiology, Fu Wai Hospital, Beijing, People's Republic of China.

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http://dx.doi.org/10.1016/j.cca.2009.03.030DOI Listing
June 2009

Gender-specific association between the kininogen 1 gene variants and essential hypertension in Chinese Han population.

J Hypertens 2009 Mar;27(3):484-90

Department of Evidence Based Medicine & Division of Population Genetics, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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March 2009

Polymorphisms of MMP-2 gene are associated with systolic heart failure risk in Han Chinese.

Am J Med Sci 2009 May;337(5):344-8

Department of Cardiology, Fu Wai Hospital, Beijing, China.

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http://dx.doi.org/10.1097/MAJ.0b013e31818eb2a2DOI Listing
May 2009

Associations of PLA2G7 gene polymorphisms with plasma lipoprotein-associated phospholipase A2 activity and coronary heart disease in a Chinese Han population: the Beijing atherosclerosis study.

Hum Genet 2009 Feb 26;125(1):11-20. Epub 2008 Nov 26.

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, 100037 Beijing, China.

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http://dx.doi.org/10.1007/s00439-008-0587-4DOI Listing
February 2009

The INSIG1 gene, not the INSIG2 gene, associated with coronary heart disease: tagSNPs and haplotype-based association study. The Beijing Atherosclerosis Study.

Thromb Haemost 2008 Nov;100(5):886-92

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular, Institute, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing, 100037, China.

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November 2008

Polymorphisms of tumor necrosis factor alpha gene and coronary heart disease in a Chinese Han population: interaction with cigarette smoking.

Thromb Res 2009 Apr 23;123(6):822-6. Epub 2008 Sep 23.

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing 100037, People's Republic of China.

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http://dx.doi.org/10.1016/j.thromres.2008.07.016DOI Listing
April 2009

Interactions among genetic variants from contractile pathway of vascular smooth muscle cell in essential hypertension susceptibility of Chinese Han population.

Pharmacogenet Genomics 2008 Jun;18(6):459-66

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.

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June 2008

A functional intronic variant in the tyrosine hydroxylase (TH) gene confers risk of essential hypertension in the Northern Chinese Han population.

Clin Sci (Lond) 2008 Sep;115(5):151-8

Department of Evidence Based Medicine, Division of Population Genetics, Cardiovascular Institute, Fu Wai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1042/CS20070335DOI Listing
September 2008

A coding polymorphism of the kallikrein 1 gene is associated with essential hypertension: a tagging SNP-based association study in a Chinese Han population.

J Hypertens 2007 Sep;25(9):1821-7

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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September 2007

Common variation in KLKB1 and essential hypertension risk: tagging-SNP haplotype analysis in a case-control study.

Hum Genet 2007 May 23;121(3-4):327-35. Epub 2007 Feb 23.

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute, Fu Wai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100037, People's Republic of China.

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May 2007