Xi Xu

Xi Xu

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Discovery of cyanopyridine scaffold as novel indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors through virtual screening and preliminary hit optimisation.

J Enzyme Inhib Med Chem 2019 Dec;34(1):250-263

a State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Design and Optimization , China Pharmaceutical University , Nanjing , People's Republic of China.

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http://dx.doi.org/10.1080/14756366.2018.1480614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327983PMC
December 2019

Degradation of Androgen Receptor through Small Molecules for Prostate Cancer.

Curr Cancer Drug Targets 2018 ;18(7):652-667

Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China.

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http://dx.doi.org/10.2174/1568009617666171107103936DOI Listing
October 2019

Design, synthesis and evaluation of phthalazinone thiohydantoin-based derivative as potent PARP-1 inhibitors.

Bioorg Chem 2019 Oct 3;91:103181. Epub 2019 Aug 3.

State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China; Department of Medicinal Chemistry, School of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.103181DOI Listing
October 2019

Efficient Mining Template of Predictive Temporal Clinical Event Patterns From Patient Electronic Medical Records.

IEEE J Biomed Health Inform 2019 09 22;23(5):2138-2147. Epub 2018 Oct 22.

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http://dx.doi.org/10.1109/JBHI.2018.2877255DOI Listing
September 2019

Berberine attenuates nonalcoholic hepatic steatosis through the AMPK-SREBP-1c-SCD1 pathway.

Free Radic Biol Med 2019 Sep 18;141:192-204. Epub 2019 Jun 18.

Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China; Fudan Institute for Metabolic Disease, Fudan University, Shanghai, 200032, China.

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http://dx.doi.org/10.1016/j.freeradbiomed.2019.06.019DOI Listing
September 2019

The progress and development of GLUT1 inhibitors targeting cancer energy metabolism.

Future Med Chem 2019 Sep;11(17):2333-2352

Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.

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http://dx.doi.org/10.4155/fmc-2019-0052DOI Listing
September 2019

Adenine nucleotide-mediated regulation of hepatic PTP1B activity in mouse models of type 2 diabetes.

Diabetologia 2019 Aug 13. Epub 2019 Aug 13.

Center for Molecular Metabolism, Nanjing University of Science & Technology, 200 Xiaolingwei, Nanjing, 210094, China.

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http://dx.doi.org/10.1007/s00125-019-04971-1DOI Listing
August 2019

Discovery of phosphonamidate IDO1 inhibitors for the treatment of non-small cell lung cancer.

Eur J Med Chem 2019 Aug 18;182:111629. Epub 2019 Aug 18.

Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.111629DOI Listing
August 2019

An Intermediary Role of Adenine Nucleotides on Free Fatty Acids-Induced Hyperglycemia in Obese Mice.

Front Endocrinol (Lausanne) 2019 6;10:497. Epub 2019 Aug 6.

Center for Molecular Metabolism, Nanjing University of Science and Technology, Nanjing, China.

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http://dx.doi.org/10.3389/fendo.2019.00497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691070PMC
August 2019

Orally administered salecan ameliorates methotrexate-induced intestinal mucositis in mice.

Cancer Chemother Pharmacol 2019 Jul 8;84(1):105-116. Epub 2019 May 8.

Center for Molecular Metabolism, Nanjing University of Science and Technology, 200 Xiaolingwei, Nanjing, 210094, Jiangsu, People's Republic of China.

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http://dx.doi.org/10.1007/s00280-019-03854-xDOI Listing
July 2019

Germline Mutations in Associated With Infantile Spasms.

Front Genet 2019 10;10:605. Epub 2019 Jul 10.

Department of Laboratory Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

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http://dx.doi.org/10.3389/fgene.2019.00605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635550PMC
July 2019

Genome-Wide Profiling of Circular RNAs in the Rapidly Growing Shoots of Moso Bamboo (Phyllostachys edulis).

Plant Cell Physiol 2019 Jun;60(6):1354-1373

College of Life Science, Basic Forestry and Proteomics Research Center, College of Forestry, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Fujian Agriculture and Forestry University, Fuzhou, China.

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https://academic.oup.com/pcp/advance-article/doi/10.1093/pcp
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http://dx.doi.org/10.1093/pcp/pcz043DOI Listing
June 2019

Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3.

FASEB J 2019 Jun 8;33(6):7289-7300. Epub 2019 Mar 8.

Department of Endocrinology and Metabolism, Affiliated Zhongshan Hospital of Fudan University, Shanghai, China.

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https://www.fasebj.org/doi/10.1096/fj.201802316R
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http://dx.doi.org/10.1096/fj.201802316RDOI Listing
June 2019

Signatures of B-cell receptor diversity in B lymphocytes following Epstein-Barr virus transformation.

Physiol Genomics 2019 Jun 19;51(6):197-207. Epub 2019 Apr 19.

Department of Clinical Laboratory, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University , Wenzhou, Zhejiang , China.

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http://dx.doi.org/10.1152/physiolgenomics.00124.2018DOI Listing
June 2019

A wave of Foxp3 regulatory T cell accumulation in the neonatal liver plays unique roles in maintaining self-tolerance.

Cell Mol Immunol 2019 Jun 6. Epub 2019 Jun 6.

Department of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Peking University, Beijing, China.

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http://dx.doi.org/10.1038/s41423-019-0246-9DOI Listing
June 2019

Pancreatic lipase-related protein 2 is responsible for the increased hepatic retinyl ester hydrolase activity in vitamin A-deficient mice.

FEBS J 2019 Jun 14. Epub 2019 Jun 14.

Center for Molecular Metabolism, Nanjing University of Science & Technology, China.

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http://dx.doi.org/10.1111/febs.14958DOI Listing
June 2019

Mesh erosion into urinary bladder with calculi formation after inguinal hernioplasty: A rare case report.

Urol Case Rep 2019 May 2;24:100590. Epub 2018 Feb 2.

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China.

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http://dx.doi.org/10.1016/j.eucr.2018.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562263PMC
May 2019

A hybrid global-local representation CNN model for automatic cataract grading.

IEEE J Biomed Health Inform 2019 May 3. Epub 2019 May 3.

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http://dx.doi.org/10.1109/JBHI.2019.2914690DOI Listing
May 2019

Diagnostic Performance of Perfusion Computed Tomography for Differentiating Lung Cancer from Benign Lesions: A Meta-Analysis.

Med Sci Monit 2019 May 11;25:3485-3494. Epub 2019 May 11.

Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China (mainland).

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https://www.medscimonit.com/abstract/index/idArt/914206
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http://dx.doi.org/10.12659/MSM.914206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526743PMC
May 2019

Liraglutide Attenuates Nonalcoholic Fatty Liver Disease through Adjusting Lipid Metabolism via SHP1/AMPK Signaling Pathway.

Int J Endocrinol 2019 19;2019:1567095. Epub 2019 May 19.

Department of Endocrinology and Metabolism, Jiangxi Institute of Endocrine and Metabolic Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang, China.

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http://dx.doi.org/10.1155/2019/1567095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545813PMC
May 2019

Synthesis of high-performance sodium carboxymethyl cellulose-based adsorbent for effective removal of methylene blue and Pb (II).

Int J Biol Macromol 2019 Apr 14;126:107-117. Epub 2018 Dec 14.

School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.

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http://dx.doi.org/10.1016/j.ijbiomac.2018.12.119DOI Listing
April 2019

The potential role of sucrose transport gene expression in the photosynthetic and yield response of rice cultivars to future CO concentration.

Physiol Plant 2019 Apr 4. Epub 2019 Apr 4.

State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China.

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http://dx.doi.org/10.1111/ppl.12973DOI Listing
April 2019

[Study on acute kidney injury model induced by renal ischemia-reperfusion in rats].

Zhongguo Zhong Yao Za Zhi 2019 Mar;44(5):996-1003

Jiangxi University of Traditional Chinese Medicine Nanchang 330006,China State Key Laboratory of Innovative Drugs and Efficient Energy-saving Pharmaceutical Equipment,Jiangxi University of Traditional Chinese Medicine Nanchang 330006,China.

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http://www.cnki.net/kcms/doi/10.19540/j.cnki.cjcmm.20181218.
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http://dx.doi.org/10.19540/j.cnki.cjcmm.20181218.001DOI Listing
March 2019

Overview of the Development of Glutaminase Inhibitors: Achievements and Future Directions.

J Med Chem 2019 Feb 7;62(3):1096-1115. Epub 2018 Sep 7.

Department of Medicinal Chemistry , China Pharmaceutical University , 24 Tongjiaxiang , Nanjing 210009 , P. R. China.

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http://pubs.acs.org/doi/10.1021/acs.jmedchem.8b00961
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http://dx.doi.org/10.1021/acs.jmedchem.8b00961DOI Listing
February 2019

Engineering of pectin-dopamine nano-conjugates for carrying ruthenium complex: A potential tool for biomedical applications.

J Inorg Biochem 2019 Feb 28;191:135-142. Epub 2018 Nov 28.

Institute of Environmental Toxicology and Environmental Ecology, Yancheng Teachers University, Yancheng City, Jiangsu Province 224007, People's Republic of China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01620134183050
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http://dx.doi.org/10.1016/j.jinorgbio.2018.11.016DOI Listing
February 2019

Discovery and development of small molecule modulators targeting glutamine metabolism.

Eur J Med Chem 2019 Feb 28;163:215-242. Epub 2018 Nov 28.

Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234183102
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http://dx.doi.org/10.1016/j.ejmech.2018.11.066DOI Listing
February 2019

Differential circRNA expression profiles in latent human cytomegalovirus infection and validation using clinical samples.

Physiol Genomics 2019 Feb 21;51(2):51-58. Epub 2018 Dec 21.

Department of Clinical Laboratory, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University , Wenzhou, Zhejiang , China.

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http://dx.doi.org/10.1152/physiolgenomics.00096.2018DOI Listing
February 2019

Cluster expansion based configurational averaging approach to bandgaps of semiconductor alloys.

Authors:
Xi Xu Hong Jiang

J Chem Phys 2019 Jan;150(3):034102

Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

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http://dx.doi.org/10.1063/1.5078399DOI Listing
January 2019

Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity.

Bioorg Chem 2018 12 30;81:373-381. Epub 2018 Aug 30.

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00452068183070
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http://dx.doi.org/10.1016/j.bioorg.2018.08.028DOI Listing
December 2018

Bimetallic Rhodium(II)/Indium(III) Relay Catalysis for Tandem Insertion/Asymmetric Claisen Rearrangement.

Angew Chem Int Ed Engl 2018 Dec 14;57(50):16554-16558. Epub 2018 Nov 14.

Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China.

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http://dx.doi.org/10.1002/anie.201810410DOI Listing
December 2018

MicroRNA-770 affects proliferation and cell cycle transition by directly targeting CDK8 in glioma.

Cancer Cell Int 2018 3;18:195. Epub 2018 Dec 3.

6Department of Cell Biology and Genetics, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061 People's Republic of China.

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http://dx.doi.org/10.1186/s12935-018-0694-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276177PMC
December 2018

Piceatannol attenuates D-GalN/LPS-induced hepatoxicity in mice: Involvement of ER stress, inflammation and oxidative stress.

Int Immunopharmacol 2018 Nov 31;64:131-139. Epub 2018 Aug 31.

Center for Molecular Metabolism, Nanjing University of Science & Technology, 200 Xiaolingwei Street, Nanjing 210094, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2018.08.037DOI Listing
November 2018

In reply to the letter to the editor regarding "Effect of initial body mass index on survival outcome of patients with myelodysplastic syndrome: a single-center retrospective study".

Leuk Lymphoma 2018 11;59(11):2762

a Division of Hematology , The First Affiliated Hospital of Wenzhou Medical University , Wenzhou , PR China.

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http://dx.doi.org/10.1080/10428194.2018.1504942DOI Listing
November 2018

Hierarchical Design of NiOOH@Amorphous Ni-P Bilayer on a 3D Mesh Substrate for High-Efficiency Oxygen Evolution Reaction.

ACS Appl Mater Interfaces 2018 Sep 29;10(36):30273-30282. Epub 2018 Aug 29.

Department of Materials Science and Engineering, Faculty of Engineering , National University of Singapore , 9 Engineering Drive 1 , Singapore 117576 , Singapore.

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http://dx.doi.org/10.1021/acsami.8b06730DOI Listing
September 2018

A Novel Synthetic UV-Curable Fluorinated Siloxane Resin for Low Surface Energy Coating.

Polymers (Basel) 2018 Sep 3;10(9). Epub 2018 Sep 3.

Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.3390/polym10090979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403602PMC
September 2018

Palladium(II)-Catalyzed Reaction of Lawsones and Propargyl Carbonates: Construction of 2,3-Furanonaphthoquinones and Evaluation as Potential Indoleamine 2,3-Dioxygenase Inhibitors.

J Org Chem 2018 08 15;83(15):8003-8010. Epub 2018 Jun 15.

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Design and Optimization , China Pharmaceutical University , Nanjing 210009 , China.

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http://dx.doi.org/10.1021/acs.joc.8b00872DOI Listing
August 2018

Creeping fat in patients with ileo-colonic Crohn's disease correlates with disease activity and severity of inflammation: A preliminary study using energy spectral computed tomography.

J Dig Dis 2018 Aug 9;19(8):475-484. Epub 2018 Sep 9.

Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1111/1751-2980.12652DOI Listing
August 2018

One-step electrodeposition of a hierarchically structured S-doped NiCo film as a highly-efficient electrocatalyst for the hydrogen evolution reaction.

Nanoscale 2018 Aug;10(32):15238-15248

School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China.

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http://dx.doi.org/10.1039/c8nr03944eDOI Listing
August 2018

Nickel(II)-Catalyzed Asymmetric Propargyl [2,3] Wittig Rearrangement of Oxindole Derivatives: A Chiral Amplification Effect.

Angew Chem Int Ed Engl 2018 07 11;57(28):8734-8738. Epub 2018 Jun 11.

Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China.

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http://dx.doi.org/10.1002/anie.201804080DOI Listing
July 2018

-glucan Salecan Improves Exercise Performance and Displays Anti-Fatigue Effects through Regulating Energy Metabolism and Oxidative Stress in Mice.

Nutrients 2018 Jul 3;10(7). Epub 2018 Jul 3.

Center for Molecular Metabolism, Nanjing University of Science & Technology, Nanjing 210094, China.

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http://dx.doi.org/10.3390/nu10070858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073659PMC
July 2018

Hippocampal FXR plays a role in the pathogenesis of depression: A preliminary study based on lentiviral gene modulation.

Psychiatry Res 2018 06 10;264:374-379. Epub 2018 Apr 10.

Department of Internal Medicine, The Second Peoples Hospital of Nantong, No. 43, XingRong Street, Tangzha Town, Nantong, Jiangsu 226002, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2018.04.025DOI Listing
June 2018

Morphometric Analysis of the Uncinate Process as a Landmark for Anterior Controllable Antedisplacement and Fusion Surgery: A Study of Radiologic Anatomy.

World Neurosurg 2018 May 5;113:e101-e107. Epub 2018 Feb 5.

Department of Spine Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China.

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http://dx.doi.org/10.1016/j.wneu.2018.01.181DOI Listing
May 2018

Doubly Screened Hybrid Functional: An Accurate First-Principles Approach for Both Narrow- and Wide-Gap Semiconductors.

J Phys Chem Lett 2018 May 24;9(9):2338-2345. Epub 2018 Apr 24.

Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Rare Earth Material Chemistry and Application, Institute of Theoretical and Computational Chemistry, College of Chemistry and Molecular Engineering , Peking University , 100871 Beijing , China.

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http://dx.doi.org/10.1021/acs.jpclett.8b00919DOI Listing
May 2018

Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme A desaturase 1 expression.

Lipids Health Dis 2018 May 14;17(1):114. Epub 2018 May 14.

Department of Endocrinology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

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http://dx.doi.org/10.1186/s12944-018-0762-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952420PMC
May 2018

Stereodivergent synthesis of vicinal quaternary-quaternary stereocenters and bioactive hyperolactones.

Nat Commun 2018 05 17;9(1):1968. Epub 2018 May 17.

Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China.

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http://www.nature.com/articles/s41467-018-04123-w
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http://dx.doi.org/10.1038/s41467-018-04123-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958103PMC
May 2018

The kinase receptor-interacting protein 1 is required for inflammasome activation induced by endoplasmic reticulum stress.

Cell Death Dis 2018 05 29;9(6):641. Epub 2018 May 29.

Center for Molecular Metabolism, Nanjing University of Science & Technology, 200 Xiaolingwei Street, Nanjing, 210094, China.

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http://www.nature.com/articles/s41419-018-0694-7
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http://dx.doi.org/10.1038/s41419-018-0694-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974395PMC
May 2018

Association between Physical Activity and Telomere Length in a North Chinese Population: A China Suboptimal Health Cohort Study.

Biomed Environ Sci 2018 May;31(5):394-398

Beijing Key Laboratory of Clinical Epidemiology, School of Public Health, Capital Medical University, Beijing 100069, China.

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http://www.besjournal.com/Articles/Archive/2018/No5/201806/t
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http://dx.doi.org/10.3967/bes2018.051DOI Listing
May 2018

Detecting the response of bird communities and biodiversity to habitat loss and fragmentation due to urbanization.

Sci Total Environ 2018 May 28;624:1561-1576. Epub 2017 Dec 28.

Department of Environmental Sciences and Engineering, Fudan University, 220 Handan Road, Shanghai 200433, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00489697173356
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http://dx.doi.org/10.1016/j.scitotenv.2017.12.143DOI Listing
May 2018

Grifolic acid induces mitochondrial membrane potential loss and cell death of RAW264.7 macrophages.

Mol Med Rep 2018 Feb 7;17(2):3281-3287. Epub 2017 Dec 7.

Institute of Basic Medical Sciences, Xi'an Medical University, Xi'an, Shaanxi 710021, P.R. China.

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http://dx.doi.org/10.3892/mmr.2017.8218DOI Listing
February 2018

Newly Generated CD4 T Cells Acquire Metabolic Quiescence after Thymic Egress.

J Immunol 2018 02 29;200(3):1064-1077. Epub 2017 Dec 29.

Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China;

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http://dx.doi.org/10.4049/jimmunol.1700721DOI Listing
February 2018

HMGA2 enhances 5-fluorouracil chemoresistance in colorectal cancer via the Dvl2/Wnt pathway.

Oncotarget 2018 Feb 10;9(11):9963-9974. Epub 2018 Jan 10.

Department of Pathology, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310058, China.

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http://dx.doi.org/10.18632/oncotarget.24133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839414PMC
February 2018

Downregulation of GLUT3 Promotes Apoptosis and Chemosensitivity of Acute Myeloid Leukemia Cells via EGFR Signaling.

Arch Iran Med 2018 02 1;21(2):73-78. Epub 2018 Feb 1.

Department of Hematology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China.

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February 2018

Effect of initial body mass index on survival outcome of patients with myelodysplastic syndrome: a single-center retrospective study.

Leuk Lymphoma 2018 01 2;59(1):129-137. Epub 2017 Jun 2.

a Division of Hematology , The First Affiliated Hospital of Wenzhou Medical University , Wenzhou , PR China.

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http://dx.doi.org/10.1080/10428194.2017.1330477DOI Listing
January 2018

Endocrinal description of two Chinese Kennedy's disease pedigrees.

J Clin Neurosci 2018 Jan 6;47:245-248. Epub 2017 Nov 6.

Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, 200032 Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.jocn.2017.10.037DOI Listing
January 2018

Exploring the tetrahydroisoquinoline thiohydantoin scaffold blockade the androgen receptor as potent anti-prostate cancer agents.

Eur J Med Chem 2018 Jan 14;143:1325-1344. Epub 2017 Oct 14.

Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.

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http://dx.doi.org/10.1016/j.ejmech.2017.10.031DOI Listing
January 2018

Putative identification of components in Zengye Decoction and their effects on glucose consumption and lipogenesis in insulin-induced insulin-resistant HepG2 cells.

J Chromatogr B Analyt Technol Biomed Life Sci 2018 Jan 12;1073:145-153. Epub 2017 Dec 12.

School of Life Sciences, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1016/j.jchromb.2017.12.019DOI Listing
January 2018

Discovery and synthesis of novel Wogonin derivatives with potent antitumor activity in vitro.

Eur J Med Chem 2017 Nov 22;140:421-434. Epub 2017 Sep 22.

Jiangsu Key Laboratory of Drug Design and Optimization, School of Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.09.046DOI Listing
November 2017

Dietary salecan reverts partially the metabolic gene expressions and NMR-based metabolomic profiles from high-fat-diet-induced obese rats.

J Nutr Biochem 2017 09 5;47:53-62. Epub 2017 May 5.

Center for Molecular Metabolism, Nanjing University of Science & Technology, Nanjing, 210094, China. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2017.04.015DOI Listing
September 2017

Berberine ameliorates fatty acid-induced oxidative stress in human hepatoma cells.

Sci Rep 2017 09 12;7(1):11340. Epub 2017 Sep 12.

Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

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http://dx.doi.org/10.1038/s41598-017-11860-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595831PMC
September 2017

Catalytic asymmetric hydroxylative dearomatization of 2-naphthols: synthesis of lacinilene derivatives.

Chem Sci 2017 Sep 24;8(9):6645-6649. Epub 2017 Jul 24.

Key Laboratory of Green Chemistry & Technology , Ministry of Education , College of Chemistry , Sichuan University , Chengdu 610064 , China . Email: ; Email: ; ; Tel: +86 28 85418249.

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http://dx.doi.org/10.1039/c7sc02809aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625263PMC
September 2017

Intestinal microbiota contributes to colonic epithelial changes in simulated microgravity mouse model.

FASEB J 2017 08 11;31(8):3695-3709. Epub 2017 May 11.

Key Laboratory of Medical Immunology, Ministry of Health, Department of Immunology, School of Basic Medical Sciences, Peking University Health Sciences Center, Beijing, China;

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http://dx.doi.org/10.1096/fj.201700034RDOI Listing
August 2017

Loss of the clock protein PER2 shortens the erythrocyte life span in mice.

J Biol Chem 2017 07 12;292(30):12679-12690. Epub 2017 Jun 12.

From the Center for Molecular Metabolism, Nanjing University of Science and Technology, 200 Xiaolingwei, Nanjing 210094, China

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535041PMC
July 2017

Dolutegravir(DTG, S/GSK1349572) combined with other ARTs is superior to RAL- or EFV-based regimens for treatment of HIV-1 infection: a meta-analysis of randomized controlled trials.

AIDS Res Ther 2016 8;13(1):30. Epub 2016 Sep 8.

Guangxi Key Laboratory of AIDS Prevention and Treatment & Guangxi Universities Key Laboratory of Prevention and Control of Highly Prevalent Disease, School of Public Health, Guangxi Medical University, Nanning, 530021 Guangxi China.

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http://dx.doi.org/10.1186/s12981-016-0115-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016965PMC
June 2017

Parthenolide attenuates cerebral ischemia/reperfusion injury via Akt/GSK-3β pathway in PC12 cells.

Biomed Pharmacother 2017 May 24;89:1159-1165. Epub 2017 Mar 24.

College of Life Sciences, Shaanxi Normal University, Xi'an 710062, People's Republic of China.

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http://dx.doi.org/10.1016/j.biopha.2017.03.009DOI Listing
May 2017

Salecan protected against concanavalin A-induced acute liver injury by modulating T cell immune responses and NMR-based metabolic profiles.

Toxicol Appl Pharmacol 2017 02 19;317:63-72. Epub 2017 Jan 19.

Center for Molecular Metabolism, Nanjing University of Science & Technology, Nanjing 210094, PR China.

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http://dx.doi.org/10.1016/j.taap.2017.01.007DOI Listing
February 2017

Design and synthesis of indoline thiohydantoin derivatives based on enzalutamide as antiproliferative agents against prostate cancer.

Eur J Med Chem 2017 Jan 22;125:1002-1022. Epub 2016 Oct 22.

Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.

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http://dx.doi.org/10.1016/j.ejmech.2016.10.049DOI Listing
January 2017

Tuberculosis screening using IGRA and chest computed tomography in patients with inflammatory bowel disease: A retrospective study.

J Dig Dis 2017 Jan;18(1):23-30

Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Inflammatory Bowel Disease Research Center, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai Institute of Digestive Disease, Shanghai, China.

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http://dx.doi.org/10.1111/1751-2980.12437DOI Listing
January 2017

Adenosine 5'-monophosphate blocks acetaminophen toxicity by increasing ubiquitination-mediated ASK1 degradation.

Oncotarget 2017 Jan;8(4):6273-6282

Center for Molecular Metabolism, Nanjing University of Science and Technology, Nanjing, 210094, China.

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http://dx.doi.org/10.18632/oncotarget.14059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351630PMC
January 2017

Evaluation and modeling of HIV based on communication theory in biological systems.

Infect Genet Evol 2016 12 29;46:241-247. Epub 2016 Aug 29.

School of Basic Medical Sciences, Wenzhou Medical University, 325000, China.

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http://dx.doi.org/10.1016/j.meegid.2016.08.032DOI Listing
December 2016

Rab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubes.

Cell Death Dis 2016 12 22;7(12):e2523. Epub 2016 Dec 22.

State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing University, Nanjing, China.

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http://dx.doi.org/10.1038/cddis.2016.441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260982PMC
December 2016

Differential effects of Rhodiola rosea on regulatory T cell differentiation and interferon‑γ production in vitro and in vivo.

Mol Med Rep 2016 Jul 13;14(1):529-36. Epub 2016 May 13.

Key Laboratory of Medical Immunology, Ministry of Health, Department of Immunology, School of Basic Medical Sciences, Peking University Health Sciences Center, Beijing 100191, P.R. China.

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http://dx.doi.org/10.3892/mmr.2016.5278DOI Listing
July 2016

Transcriptional activation of FN1 and IL11 by HMGA2 promotes the malignant behavior of colorectal cancer.

Carcinogenesis 2016 05 10;37(5):511-21. Epub 2016 Mar 10.

Department of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China

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http://dx.doi.org/10.1093/carcin/bgw029DOI Listing
May 2016

Pif1 is a force-regulated helicase.

Nucleic Acids Res 2016 05 20;44(9):4330-9. Epub 2016 Apr 20.

Beijing National Laboratory for Condensed Matter Physics and CAS Key Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China

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http://dx.doi.org/10.1093/nar/gkw295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872122PMC
May 2016

Progress in the mechanism and drug development of castration-resistant prostate cancer.

Future Med Chem 2016 05 5;8(7):765-88. Epub 2016 May 5.

Department of Medicinal Chemistry, China Pharmaceutical University, #24 Tongjiaxiang, Nanjing 210009, PR China.

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http://dx.doi.org/10.4155/fmc.16.12DOI Listing
May 2016

MicroRNA-25 Negatively Regulates Cerebral Ischemia/Reperfusion Injury-Induced Cell Apoptosis Through Fas/FasL Pathway.

J Mol Neurosci 2016 Apr 14;58(4):507-16. Epub 2016 Jan 14.

College of Life Sciences, Shaanxi Normal University, Xi'an, 710062, People's Republic of China.

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http://dx.doi.org/10.1007/s12031-016-0712-0DOI Listing
April 2016

Abbreviated half-lives and impaired fuel utilization in carnitine palmitoyltransferase II variant fibroblasts.

PLoS One 2015 17;10(3):e0119936. Epub 2015 Mar 17.

School of Life Sciences, Key Laboratory of Neuroregeneration, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu, P. R. China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364069PMC
March 2016

Design, synthesis and biological evaluation of 3-substituted indenoisoquinoline derivatives as topoisomerase I inhibitors.

Bioorg Med Chem Lett 2016 Feb 7;26(3):1068-1072. Epub 2015 Dec 7.

Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2015.12.014DOI Listing
February 2016

Role of sul2 gene linked to transposase in resistance to trimethoprim/sulfamethoxazole among Stenotrophomonas maltophilia isolates.

Ann Lab Med 2016 Jan;36(1):73-5

Department of Infectious Diseases, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

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http://synapse.koreamed.org/DOIx.php?id=10.3343/alm.2016.36.
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http://dx.doi.org/10.3343/alm.2016.36.1.73DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697349PMC
January 2016

Liver sinusoidal endothelial cells induce tolerance of autoreactive CD4+ recent thymic emigrants.

Sci Rep 2016 Jan 22;6:19861. Epub 2016 Jan 22.

Key Laboratory of Medical Immunology, Ministry of Health. Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, 38 Xue Yuan Road, Beijing, 100191, P. R. China.

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http://dx.doi.org/10.1038/srep19861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726350PMC
January 2016

Trx1/TrxR1 system regulates post-selected DP thymocytes survival by modulating ASK1-JNK/p38 MAPK activities.

Immunol Cell Biol 2015 Sep 10;93(8):744-52. Epub 2015 Mar 10.

Key Laboratory of Medical Immunology, Department of Immunology, Ministry of Health, School of Basic Medical Sciences, Peking University Health Science Center, 38 Xue Yuan Road, Beijing, China.

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http://dx.doi.org/10.1038/icb.2015.36DOI Listing
September 2015

Simulated microgravity disrupts intestinal homeostasis and increases colitis susceptibility.

FASEB J 2015 Aug 15;29(8):3263-73. Epub 2015 Apr 15.

*Key Laboratory of Medical Immunology, Ministry of Health, Department of Immunology, School of Basic Medical Sciences, and Peking University Medical and Health Analytical Center, Peking University Health Sciences Center, Beijing, China; State Key Laboratory of Space Medicine Fundamentals and Application, Chinese Astronaut Research and Training Center, Beijing, China; and College of Life Sciences and Key Laboratory of Modern Teaching Technology, Shaanxi Normal University, Xian, China

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http://dx.doi.org/10.1096/fj.15-271700DOI Listing
August 2015

An indica rice genotype showed a similar yield enhancement to that of hybrid rice under free air carbon dioxide enrichment.

Sci Rep 2015 Jul 31;5:12719. Epub 2015 Jul 31.

State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Sciences, Chinese Academy of Sciences, East Beijing Road, Nanjing, 210008, PR China.

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http://dx.doi.org/10.1038/srep12719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521144PMC
July 2015

Decreased LINE-1 methylation levels in aldosterone-producing adenoma.

Int J Clin Exp Pathol 2014 15;7(7):4104-11. Epub 2014 Jun 15.

Department of Endocrinology, Zhongshan Hospital, Fudan University Shanghai, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129024PMC
May 2015

High suppressor of cytokine signaling-3 expression impairs STAT3-dependent protective effects of interleukin-22 in ulcerative colitis in remission.

Inflamm Bowel Dis 2015 Feb;21(2):241-50

Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.

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February 2015

Retention and tolerance of autoreactive CD4(+) recent thymic emigrants in the liver.

J Autoimmun 2015 Jan 14;56:87-97. Epub 2014 Nov 14.

Key Laboratory of Medical Immunology, Ministry of Health, Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, 38 Xue Yuan Road, Beijing 100191, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2014.10.006DOI Listing
January 2015

Characterization of biochemical properties of Bacillus subtilis RecQ helicase.

J Bacteriol 2014 Dec 22;196(24):4216-28. Epub 2014 Sep 22.

College of Life Sciences, Northwest A & F University, Yangling, Shaanxi, China Laboratoire de Biologie et Pharmacologie Appliquée, CNRS UMR8113, Ecole Normale Supérieure Cachan, Institut d'Alembert, Cachan, France

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http://dx.doi.org/10.1128/JB.06367-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248853PMC
December 2014

The effects of claudin 14 during early Wallerian degeneration after sciatic nerve injury.

Neural Regen Res 2014 Dec;9(24):2151-8

Jiangsu Key Laboratory of Neuroregeneration, Co-innovation Center of Neuroregeneration, Nantong, Jiangsu Province, China ; School of Life Sciences, Nantong University, Nantong, Jiangsu Province, China.

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http://dx.doi.org/10.4103/1673-5374.147946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316448PMC
December 2014

Three new diphenylpropanes from Celastrus hindsii.

Arch Pharm Res 2014 Nov 30;37(11):1411-5. Epub 2013 Nov 30.

School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China.

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http://dx.doi.org/10.1007/s12272-013-0296-yDOI Listing
November 2014

Developmental profile of neurogenesis in prenatal human hippocampus: an immunohistochemical study.

Int J Dev Neurosci 2014 Nov 3;38:1-9. Epub 2014 Jul 3.

Institute of Neurobiology, Department of Human Anatomy and Histoembryology, Xi'an Jiaotong University College of Medicine, Xi'an, China. Electronic address:

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http://dx.doi.org/10.1016/j.ijdevneu.2014.06.015DOI Listing
November 2014

Maturation and emigration of single-positive thymocytes.

Clin Dev Immunol 2013 29;2013:282870. Epub 2013 Sep 29.

Key Laboratory of Medical Immunology, Department of Immunology, Peking University Health Science Center, Ministry of Health, 38 Xue Yuan Road, Beijing 100191, China.

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http://dx.doi.org/10.1155/2013/282870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804360PMC
June 2014

Maturation and migration of murine CD4 single positive thymocytes and thymic emigrants.

Authors:
Xi Xu Qing Ge

Comput Struct Biotechnol J 2014 30;9:e201403003. Epub 2014 Mar 30.

Key Laboratory of Medical Immunology, Ministry of Health. Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, 38 Xue Yuan Road, Beijing 100191, P R China.

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http://dx.doi.org/10.5936/csbj.201403003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995209PMC
June 2014

mGluR5 promotes the differentiation of rat neural progenitor cells into cholinergic neurons and activation of extracellular signal-related protein kinases.

Neuroreport 2014 Apr;25(6):427-34

aInstitute of Neurobiology bDepartment of Genetics and Cell Biology, Environment and Genes Related to Diseases Key Laboratory of Education Ministry, Xi'an Jiaotong University College of Medicine cDepartment of Anatomy, Xi'an Medical University, Xi'an, People's Republic of China.

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http://dx.doi.org/10.1097/WNR.0000000000000134DOI Listing
April 2014

A new mutation in the CSB gene in a Chinese patient with mild Cockayne syndrome.

Clin Case Rep 2014 Apr 7;2(2):33-6. Epub 2014 Feb 7.

Zhongshan Hospital Fudan University Shanghai, China.

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http://dx.doi.org/10.1002/ccr3.47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184625PMC
April 2014