Xavier Decleves

Xavier Decleves

UNVERIFIED PROFILE

Are you Xavier Decleves?   Register this Author

Register author
Xavier Decleves

Xavier Decleves

Publications by authors named "Xavier Decleves"

Are you Xavier Decleves?   Register this Author

96Publications

3289Reads

5Profile Views

Glucocorticoids dosing in obese subjects: A systematic review.

Therapie 2019 Sep 14;74(4):451-458. Epub 2019 Feb 14.

Groupe Ramsay-Générale de Santé, Hôpital Privé Pays de Savoie, Maladies Nutritionnelles et Métaboliques, 74100 Annemasse, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.therap.2018.11.016DOI Listing
September 2019

CYP450 activities before and after Roux-en-Y gastric bypass: correlation with their intestinal and liver content.

Surg Obes Relat Dis 2019 Aug 20;15(8):1299-1310. Epub 2019 May 20.

Assistance Publique-Hôpitaux de Paris, Hôpital Cochin, Biologie du Médicament et Toxicologie, Paris, France; Inserm, UMR-S 1144 Université Paris Descartes-Paris Diderot, Variabilité de réponse aux psychotropes, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.soard.2019.05.019DOI Listing
August 2019

LC-MS/MS-based quantification of efflux transporter proteins at the BBB.

J Pharm Biomed Anal 2019 Feb 8;164:496-508. Epub 2018 Nov 8.

Inserm, UMR-S 1144, Response Variability to Psychotropics, Paris, France; Université Paris Descartes, Paris, France; Université Paris Diderot, Paris, France; UF Hormonologie, Hôpital Cochin, AP HP, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S07317085183071
Publisher Site
http://dx.doi.org/10.1016/j.jpba.2018.11.013DOI Listing
February 2019

Humanization of the Blood-Brain Barrier Transporter ABCB1 in Mice Disrupts Genomic Locus - Lessons from Three Unsuccessful Approaches.

Eur J Microbiol Immunol (Bp) 2018 Sep 6;8(3):78-86. Epub 2018 Jul 6.

Translational Neurodegeneration Research and Neuropathology Lab, Department of Neuro-Pathology, University of Oslo and Oslo University Hospital, Oslo, Norway.

View Article

Download full-text PDF

Source
https://www.akademiai.com/doi/10.1556/1886.2018.00008
Publisher Site
http://dx.doi.org/10.1556/1886.2018.00008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186017PMC
September 2018

Influence of PLA-PEG nanoparticles manufacturing process on intestinal transporter PepT1 targeting and oxytocin transport.

Eur J Pharm Biopharm 2018 Aug 24;129:122-133. Epub 2018 May 24.

Inserm, U1144, Paris F-75006, France; Université Paris Descartes, UMR-S 1144, Faculté de Pharmacie de Paris, Paris F-75006, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejpb.2018.05.022DOI Listing
August 2018

High brain distribution of a new central nervous system drug candidate despite its P-glycoprotein-mediated efflux at the mouse blood-brain barrier.

Eur J Pharm Sci 2018 May 7;117:68-79. Epub 2018 Feb 7.

Variabilité de Réponse aux Psychotropes, Inserm, U1144, Paris F-75006, France; Faculté de Pharmacie de Paris, Université Paris Descartes, UMR-S 1144, Paris F-75006, France; Université Paris Diderot, UMR-S 1144, Paris F-75013, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejps.2018.02.005DOI Listing
May 2018

Population pharmacokinetics of oral baclofen at steady-state in alcoholic-dependent adult patients.

Fundam Clin Pharmacol 2018 Apr 23;32(2):239-248. Epub 2017 Nov 23.

Inserm, UMR-S 1144, Université Paris Descartes - Paris Diderot, Variabilité de Réponse Aux Psychotropes, Paris, F-75006, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/fcp.12330DOI Listing
April 2018

An observational study of benzodiazepine prescription during inpatient alcohol detoxification for patients with vs. without chronic pretreatment with high-dosage baclofen.

Fundam Clin Pharmacol 2018 Apr 11;32(2):200-205. Epub 2018 Jan 11.

Groupe Hospitalier Saint-Louis- Lariboisière - Fernand Widal, Service de Pharmacie, Assistance Publique - Hôpitaux de Paris, 200 rue du Faubourg Saint Denis, Paris, 75010, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/fcp.12339DOI Listing
April 2018

Double or Simple Emulsion Process to Encapsulate Hydrophilic Oxytocin Peptide in PLA-PEG Nanoparticles.

Pharm Res 2018 Mar 5;35(4):82. Epub 2018 Mar 5.

Technologie Servier, 27 rue Eugène Vignat, Orléans, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11095-018-2358-9DOI Listing
March 2018

Opioids and the Blood-Brain Barrier: A Dynamic Interaction with Consequences on Drug Disposition in Brain.

Curr Neuropharmacol 2017 Nov;15(8):1156-1173

Variabilite de Reponse Aux Psychotropes, INSERM, U1144, 75006 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1570159X15666170504095823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725546PMC
November 2017

Morphine and metabolites plasma levels after administration of sustained release morphine in Roux-en-Y gastric bypass subjects versus matched control subjects.

Surg Obes Relat Dis 2017 Nov 3;13(11):1869-1874. Epub 2017 Aug 3.

Inserm U1144, Paris, France; Therapeutic Research Unit, Department of Internal Medicine, Assistance Publique-Hôpitaux de Paris, Hôpital Lariboisière, Paris, France; Université Paris Diderot, UMR-S 1144, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15507289173035
Publisher Site
http://dx.doi.org/10.1016/j.soard.2017.07.030DOI Listing
November 2017

Imaging Probes and Modalities for the Study of Solute Carrier O (SLCO)-Transport Function In Vivo.

J Pharm Sci 2017 09 25;106(9):2335-2344. Epub 2017 Apr 25.

Imagerie Moléculaire In Vivo, IMIV, CEA, INSERM, CNRS, Université Paris-Sud, Université Paris Saclay, CEA-SHFJ, Orsay, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.xphs.2017.04.031DOI Listing
September 2017

Liquid chromatography high resolution mass spectrometry for the determination of baclofen and its metabolites in plasma: Application to therapeutic drug monitoring.

Biomed Chromatogr 2017 Aug 17;31(8). Epub 2017 Feb 17.

Biologie du Médicament et Toxicologie, Groupe Cochin (Assistance Publique - Hôpitaux de Paris), France.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/bmc.3936
Publisher Site
http://dx.doi.org/10.1002/bmc.3936DOI Listing
August 2017

Functionalized PLA-PEG nanoparticles targeting intestinal transporter PepT1 for oral delivery of acyclovir.

Int J Pharm 2017 Aug 10;529(1-2):357-370. Epub 2017 Jul 10.

Inserm, U1144, Paris, F-75006, France; Université Paris Descartes, UMR-S 1144, Faculté de Pharmacie de Paris, Paris, F-75006, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpharm.2017.07.024DOI Listing
August 2017

Aryl hydrocarbon receptor upregulates IL-1β expression in hCMEC/D3 human cerebral microvascular endothelial cells after TCDD exposure.

Toxicol In Vitro 2017 Jun 8;41:200-204. Epub 2017 Mar 8.

INSERM, UMR-S 1144, Paris F-75006, France; Université Paris Descartes, UMR-S 1144, Paris F-75006, France; Université Paris Diderot, UMR-S 1144, Paris F-75013, France. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08872333173006
Publisher Site
http://dx.doi.org/10.1016/j.tiv.2017.03.001DOI Listing
June 2017

The effect of morbid obesity on morphine glucuronidation.

Pharmacol Res 2017 04 5;118:64-70. Epub 2016 Sep 5.

Inserm, UMR-S 1144 Université Paris Descartes-Paris Diderot, Variabilité de réponse aux psychotropes, France; Assistance Publique-Hôpitaux de Paris, Hôpital Cochin, Pharmacokinetics and Pharmacochemistry Unit, Paris F-75014, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2016.08.031DOI Listing
April 2017

RYGB and Drug Disposition: How to Do Better? Analysis of Pharmacokinetic Studies and Recommendations for Clinical Practice.

Obes Surg 2017 04;27(4):1076-1090

Assistance Publique-Hôpitaux de Paris, Hôpital Lariboisière, Therapeutic Research Unit, Department of Internal Medicine, Paris, F-75010, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11695-016-2535-zDOI Listing
April 2017

Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface.

Cell Discov 2017 28;3:17005. Epub 2017 Mar 28.

Neuroglial Interactions in Cerebral Physiopathology/Collège de France, Center for Interdisciplinary Research in Biology (CIRB)/Centre National de la Recherche Scientifique CNRS, UMR 7241/Institut National de la Santé et de la Recherche Médicale INSERM, U1050/University Pierre et Marie Curie UPMC, ED, No. 158/MEMOLIFE Laboratory of Excellence and PSL Research University , Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/celldisc.2017.5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368712PMC
March 2017

The effect of morbid obesity on morphine glucuronidation.

Pharmacol Res 2016 Dec 28;114:299-300. Epub 2016 Sep 28.

INSERM U1144, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2016.09.034DOI Listing
December 2016

Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model.

Mol Pharmacol 2016 May 18;89(5):492-504. Epub 2016 Feb 18.

DMPK and Bioanalytical Research, Abbvie Deutschland GmbH & Co. KG, Ludwigshafen, Germany (M.M., C.H., L.L.); Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA (L.S., J.P., X.Z.); Drug Metabolism and Pharmacokinetics, GlaxoSmithKline Pharmaceuticals, King of Prussia, Pennsylvania (L.C., C.A., E.P.); Health and Environment Department, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria (T.W., O.L.); Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria (O.L.), Preclinical Development and Safety, Janssen Research and Development, LLC, Spring House, PA (S.D., J.K., K.D., D.S.). Merck Sharp and Dohme Corporation, Whitehouse Station, New Jersey (X.C., T.P., J.Y.); Université Paris Descartes, UMR-S 1144, Paris, France (D.G.-Z., M.-C.M., S.C., X.D.); Taconic Biosciences GmbH, Koeln, Germany (A.R., N.S.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/mol.115.102079DOI Listing
May 2016

Is extracorporeal treatment useful for managing severe baclofen poisoning? - The debate is still open.

Anaesth Crit Care Pain Med 2016 Apr 4;35(2):171-2. Epub 2016 Feb 4.

Inserm UMR-S1144, pharmacocinétique et pharmacochimie, hôpital Cochin, université Paris Descartes, 75014 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.accpm.2016.02.001DOI Listing
April 2016

Population pharmacokinetics and dosing optimization of teicoplanin in children with malignant haematological disease.

Br J Clin Pharmacol 2015 Nov 5;80(5):1197-207. Epub 2015 Sep 5.

Sino-French Pediatric Research Center, Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bcp.12710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631192PMC
November 2015

Usefulness of plasma drug monitoring in severe baclofen poisoning.

Clin Toxicol (Phila) 2015 Nov;53(9):923-4

d Assistance Publique - Hôpitaux de Paris, Hôpital Lariboisière, Réanimation Médicale et Toxicologique and Inserm UMR-S 1144; Université Paris-Diderot , Paris , France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/15563650.2015.1088158DOI Listing
November 2015

Purification of Mouse Brain Vessels.

J Vis Exp 2015 Nov 10(105):e53208. Epub 2015 Nov 10.

Collège de France, Center for Interdisciplinary Research in Biology (CIRB), Centre National de la Recherche Scientifique CNRS, Unité Mixte de Recherche 7241, Institut National de la Santé et de la Recherche Médicale; Centre Interdisciplinaire de Recherche en Biologie; MEMOLIFE Laboratory of Excellence and Paris Science, Lettre Research University;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3791/53208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692710PMC
November 2015

Aryl hydrocarbon receptor regulates CYP1B1 but not ABCB1 and ABCG2 in hCMEC/D3 human cerebral microvascular endothelial cells after TCDD exposure.

Brain Res 2015 Jul 7;1613:27-36. Epub 2015 Apr 7.

INSERM, UMR-S 1144, Paris F-75006, France; Université Paris Descartes, UMR-S 1144, Paris F-75006, France; Université Paris Diderot, UMR-S 1144, Paris F-75013, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2015.03.049DOI Listing
July 2015

Hypoxia interferes with aryl hydrocarbon receptor pathway in hCMEC/D3 human cerebral microvascular endothelial cells.

J Neurochem 2015 Feb 14;132(4):373-83. Epub 2014 Nov 14.

INSERM, UMR-S 1144, Paris, France; Université Paris Descartes, UMR-S 1144, Paris, France; Université Paris Diderot, UMR-S 1144, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jnc.12972DOI Listing
February 2015

Antidepressant agents in short bowel syndrome.

Clin Ther 2014 Dec 29;36(12):2029-2033.e3. Epub 2014 Oct 29.

VariaPsy, Variability of the Response to Psychotropic Drugs, Paris Descartes and Paris Diderot Universities, Paris, France; Unit of Therapeutic Research, Department of Internal Medicine, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinthera.2014.09.018DOI Listing
December 2014

Human ABC transporters at blood-CNS interfaces as determinants of CNS drug penetration.

Curr Pharm Des 2014 ;20(10):1450-62

Neuropsychopharmacologie des addictions (CNRS UMR 8206), Université Paris Descartes, Faculté de Pharmacie, Paris, France

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/13816128113199990466DOI Listing
November 2014

Comparing translational population-PBPK modelling of brain microdialysis with bottom-up prediction of brain-to-plasma distribution in rat and human.

Biopharm Drug Dispos 2014 Nov 17;35(8):485-99. Epub 2014 Sep 17.

Centre de Pharmacocinétique et Métabolisme, Groupe de Recherche Servier, Orléans, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bdd.1908DOI Listing
November 2014

Effect of a Roux-en-Y gastric bypass on the pharmacokinetics of oral morphine using a population approach.

Clin Pharmacokinet 2014 Oct;53(10):919-30

Inserm, UMR-S 1144 Université Paris Descartes-Paris Diderot, Variabilité de réponse aux psychotropes, Paris, France,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40262-014-0163-0DOI Listing
October 2014

Carrier-mediated cocaine transport at the blood-brain barrier as a putative mechanism in addiction liability.

Int J Neuropsychopharmacol 2014 Oct 31;18(1). Epub 2014 Oct 31.

Variabilité de réponse aux psychotropes, INSERM, U1144, 75006 Paris, France (Drs. Chapy, Smirnova, André, Scherrmann, Declèves, Cisternino); Université Paris Descartes, UMR-S 1144, Paris, F-75006, France (Drs. Chapy, Smirnova, André, Scherrmann, Declèves, Cisternino); Université Paris Diderot, UMR-S 1144, Paris, F-75013, France (Drs. Chapy, Smirnova, André, Scherrmann, Declèves, Cisternino); Assistance publique hôpitaux de Paris, AP-HP, Jean Verdier, Bondy, F-93140, France (Drs. Schlatter, Chiadmi, Cisternino); INSERM, U1016, Institut Cochin, 75014, Paris, France (Dr. Couraud); CNRS, UMR8104, Paris, France (Dr. Couraud); Université Paris Descartes, Sorbonne Paris Cité, Paris, France (Dr. Couraud).

View Article

Download full-text PDF

Source
https://academic.oup.com/ijnp/article-lookup/doi/10.1093/ijn
Publisher Site
http://dx.doi.org/10.1093/ijnp/pyu001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368859PMC
October 2014

A physiologically based modeling strategy during preclinical CNS drug development.

Mol Pharm 2014 Mar 29;11(3):836-48. Epub 2014 Jan 29.

Centre de Pharmacocinétique et Métabolisme, Groupe de Recherche Servier , Orléans, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/mp400533qDOI Listing
March 2014

Synthetic lipid nanoparticles targeting steroid organs.

J Nucl Med 2013 Nov 26;54(11):1996-2003. Epub 2013 Sep 26.

Inserm U1023, I2BM/SHFJ, CEA, Orsay, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.113.121657DOI Listing
November 2013

Respiratory effects of diazepam/methadone combination in rats: a study based on concentration/effect relationships.

Drug Alcohol Depend 2013 Aug 15;131(3):298-307. Epub 2013 Jan 15.

INSERM U705, CNRS UMR8206, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Pharmacie, Neuropsychopharmacologie des addictions, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2012.12.020DOI Listing
August 2013

Impact of prescriber's handwriting style and nurse's duty duration on the prevalence of transcription errors in public hospitals.

J Clin Nurs 2013 Feb 10;22(3-4):550-8. Epub 2012 Dec 10.

INSERM U705, Neuropsychopharmacologie des addictions, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2702.2012.04076.xDOI Listing
February 2013

Hurdles with using in vitro models to predict human blood-brain barrier drug permeability: a special focus on transporters and metabolizing enzymes.

Curr Drug Metab 2013 Jan;14(1):120-36

Neuropsychopharmacologie des addictions (CNRS UMR 8206), Université Paris Descartes, Faculté de Pharmacie, Paris, France.

View Article

Download full-text PDF

Source
January 2013

Respiratory toxicity of buprenorphine results from the blockage of P-glycoprotein-mediated efflux of norbuprenorphine at the blood-brain barrier in mice.

Crit Care Med 2012 Dec;40(12):3215-23

INSERM U705, CNRS UMR8206, Université Paris Descartes, Université Paris Diderot, Sorbonne Paris Cité, Faculté de Pharmacie, Neuropsychopharmacologie des addictions, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0b013e318265680aDOI Listing
December 2012

Induction of P-glycoprotein and Bcrp at the rat blood-brain barrier following a subchronic morphine treatment is mediated through NMDA/COX-2 activation.

J Neurochem 2012 Nov 3;123(4):491-503. Epub 2012 Sep 3.

CNRS, UMR 8206, Neuropsychopharmacologie des addictions, Faculté des Sciences Pharmaceutiques et Biologiques, Université Paris Descartes, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1471-4159.2012.07890.xDOI Listing
November 2012

Opioid transport by ATP-binding cassette transporters at the blood-brain barrier: implications for neuropsychopharmacology.

Curr Pharm Des 2011 ;17(26):2829-42

INSERM U705, CNRS UMR 8206, Université Paris Descartes et Université Paris Diderot, Neuropsychopharmacologie des addictions, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/138161211797440203DOI Listing
March 2012

Etonorgestrel concentrations in morbidly obese women following Roux-en-Y gastric bypass surgery: three case reports.

Contraception 2011 Dec 8;84(6):649-51. Epub 2011 May 8.

Department of Nutrition, Pitié-Salpêtrière Hospital (AP-HP), University Pierre et Marie Curie-Paris 6, 75013 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.contraception.2011.03.015DOI Listing
December 2011

Electronic prescribing reduces prescribing error in public hospitals.

J Clin Nurs 2011 Nov 31;20(21-22):3233-45. Epub 2011 May 31.

Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2702.2011.03714.xDOI Listing
November 2011

Interplay of drug metabolizing CYP450 enzymes and ABC transporters in the blood-brain barrier.

Curr Drug Metab 2011 Oct;12(8):732-41

Neuropsychopharmacologie des addictions (CNRS UMR 8206), Université Paris Descartes, Faculté de Pharmacie, Paris, France.

View Article

Download full-text PDF

Source
October 2011

Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels.

Fluids Barriers CNS 2011 Aug 25;8:23. Epub 2011 Aug 25.

Neuropsychopharmacologie des addictions (CNRS UMR 8206), Université Paris Descartes, Sorbonne Paris Cité, Faculté de Pharmacie, Paris, France.

View Article

Download full-text PDF

Source
http://fluidsbarrierscns.biomedcentral.com/articles/10.1186/
Publisher Site
http://dx.doi.org/10.1186/2045-8118-8-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180256PMC
August 2011

Validity of leg-to-leg bioelectrical impedance analysis to estimate body fat in obesity.

Obes Surg 2011 Jul;21(7):917-23

Department of Nutrition, Pitié-Salpêtrière Hospital (AP-HP), University Pierre et Marie Curie-Paris 6, 83, Boulevard de l'Hôpital, 75013, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11695-010-0296-7DOI Listing
July 2011

Population pharmacokinetics of 3,4-methylenedioxymethamphetamine and main metabolites in rats.

Toxicol Sci 2010 Mar 14;114(1):38-47. Epub 2009 Dec 14.

Faculté de Pharmacie, Université Paris Descartes, Paris F-75006, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfp300DOI Listing
March 2010

Influence of development, HIV infection, and antiretroviral therapies on the gene expression profiles of ABC transporters in human lymphocytes.

J Clin Pharmacol 2010 Feb 16;50(2):226-30. Epub 2009 Oct 16.

Centre de Recherche Clinique Paris Descartes, Groupe Hospitalier Cochin-Saint-Vincent-de-Paul, Assistance Publique-Hôpitaux de Paris, Site Hôpital Tarnier, 75006 Paris, France.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1177/0091270009343696
Publisher Site
http://dx.doi.org/10.1177/0091270009343696DOI Listing
February 2010

Mechanisms of respiratory insufficiency induced by methadone overdose in rats.

Addict Biol 2010 Jan;15(1):62-80

Université Paris-Descartes, Faculté de Pharmacie, Neuropsychopharmacologie des addictions, CNRS, UMR 7157, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1369-1600.2009.00184.xDOI Listing
January 2010

Ibogaine labeling with 99mTc-tricarbonyl: synthesis and transport at the mouse blood-brain barrier.

J Pharm Sci 2009 Dec;98(12):4650-60

INSERM U705, CNRS UMR 7157, Université Paris Descartes, Université Paris Diderot, Hôpital F. Widal, 200, rue du Fbg Saint Denis, 75010 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jps.21771DOI Listing
December 2009

Pharmacology of morphine in obese patients: clinical implications.

Clin Pharmacokinet 2009 ;48(10):635-51

Unit of Therapeutic Research, Department of Internal Medicine, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France.

View Article

Download full-text PDF

Source
http://link.springer.com/10.2165/11317150-000000000-00000
Publisher Site
http://dx.doi.org/10.2165/11317150-000000000-00000DOI Listing
December 2009

Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells.

Biochem Pharmacol 2009 Mar 12;77(5):897-909. Epub 2008 Nov 12.

Neuropsychopharmacologie des addictions (CNRS UMR 7157), Université Paris Descartes, Faculté de Pharmacie, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2008.11.001DOI Listing
March 2009

Effect of chronic exposure to morphine on the rat blood-brain barrier: focus on the P-glycoprotein.

J Neurochem 2008 Nov 30;107(3):647-57. Epub 2008 Aug 30.

CNRS, UMR 7157 et Université Paris 7, Neuropsychopharmacologie des addictions, Faculté des Sciences Pharmaceutiques et Biologiques, Université Paris Descartes, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1471-4159.2008.05647.xDOI Listing
November 2008

Squalenoylation favorably modifies the in vivo pharmacokinetics and biodistribution of gemcitabine in mice.

Drug Metab Dispos 2008 Aug 12;36(8):1570-7. Epub 2008 May 12.

Faculté de Pharmacie, Unité Mixte de Recherche Centre National de la Recherche Scientifique 8612, Institut Fédératif de Recherche 141, Université Paris XI, Châtenay-Malabry cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/dmd.108.020735DOI Listing
August 2008

ABC transporters and the accumulation of imatinib and its active metabolite CGP74588 in rat C6 glioma cells.

Pharmacol Res 2008 Mar 2;57(3):214-22. Epub 2008 Feb 2.

Université Paris Descartes, Faculté de Pharmacie, Neuropsychopharmacologie des addictions, CNRS, UMR7157 et Université Paris 7, Paris F-75010, France.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S104366180800016
Publisher Site
http://dx.doi.org/10.1016/j.phrs.2008.01.006DOI Listing
March 2008

Case report: quantification of methadone-induced respiratory depression using toxicokinetic/toxicodynamic relationships.

Crit Care 2007 ;11(1):R5

INSERM U705, CNRS, UMR 7157, Université Paris 7, Assistance Publique--Hôpitaux de Paris, Hôpital Lariboisière, Réanimation Médicale et Toxicologique, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/cc5150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151854PMC
May 2007

Expression of drug transporters at the blood-brain barrier using an optimized isolated rat brain microvessel strategy.

Brain Res 2007 Feb 28;1134(1):1-11. Epub 2006 Dec 28.

INSERM U705, CNRS, UMR 7157, University Paris 5, Neuropsychopharmacology of Addiction, Laboratory of Pharmacokinetics, Faculty of Pharmacy, Hôpital Fernand Widal, Paris, France.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S000689930603467
Publisher Site
http://dx.doi.org/10.1016/j.brainres.2006.11.089DOI Listing
February 2007

Is P-glycoprotein (ABCB1) a phase 0 or a phase 3 colchicine transporter depending on colchicine exposure conditions?

Toxicol Appl Pharmacol 2006 Dec 10;217(2):153-60. Epub 2006 Aug 10.

INSERM U705, 200 rue du Fbg St Denis, 75475 Paris Cedex 10, France.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0041008X0600270
Publisher Site
http://dx.doi.org/10.1016/j.taap.2006.08.004DOI Listing
December 2006

Role of ABC transporters in the chemoresistance of human gliomas.

Curr Cancer Drug Targets 2006 Aug;6(5):433-45

INSERM U705 UMR CNRS 7157, Laboratory of Neuropsychopharmacology, Faculty of Pharmacy, Paris, France.

View Article

Download full-text PDF

Source
August 2006