Wuxian Shi

Wuxian Shi

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Wuxian Shi

Wuxian Shi

Publications by authors named "Wuxian Shi"

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SDS22 selectively recognizes and traps metal-deficient inactive PP1.

Proc Natl Acad Sci U S A 2019 Oct 23;116(41):20472-20481. Epub 2019 Sep 23.

Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721;

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http://dx.doi.org/10.1073/pnas.1908718116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789808PMC
October 2019

Structure of the dihydrolipoamide succinyltransferase catalytic domain from Escherichia coli in a novel crystal form: a tale of a common protein crystallization contaminant.

Acta Crystallogr F Struct Biol Commun 2019 Sep 29;75(Pt 9):616-624. Epub 2019 Aug 29.

National Synchrotron Light Source II, Brookhaven National Laboratory, Upton, NY 11973-5000, USA.

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http://dx.doi.org/10.1107/S2053230X19011488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718150PMC
September 2019

Evidence for distinct rate-limiting steps in the cleavage of alkenes by carotenoid cleavage dioxygenases.

J Biol Chem 2019 07 28;294(27):10596-10606. Epub 2019 May 28.

From the Department of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106,

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http://dx.doi.org/10.1074/jbc.RA119.007535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615678PMC
July 2019

Synchrotron microcrystal native-SAD phasing at a low energy.

IUCrJ 2019 Jul 3;6(Pt 4):532-542. Epub 2019 May 3.

Biology Department, Brookhaven National Laboratory, Upton, NY 11973, USA.

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http://dx.doi.org/10.1107/S2052252519004536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608635PMC
July 2019

A Metastable Contact and Structural Disorder in the Estrogen Receptor Transactivation Domain.

Structure 2019 02 20;27(2):229-240.e4. Epub 2018 Dec 20.

Center for Proteomics and Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA; Department of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2018.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365180PMC
February 2019

Preparation and characterization of metal-substituted carotenoid cleavage oxygenases.

J Biol Inorg Chem 2018 08 26;23(6):887-901. Epub 2018 Jun 26.

Department of Pharmacology, School of Medicine, Case Western Reserve University, 10900 Euclid Ave., Cleveland, OH, 44106, USA.

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http://link.springer.com/10.1007/s00775-018-1586-0
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http://dx.doi.org/10.1007/s00775-018-1586-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060882PMC
August 2018

Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.

Proc Natl Acad Sci U S A 2018 06 11;115(26):6792-6797. Epub 2018 Jun 11.

Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH 44106;

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http://dx.doi.org/10.1073/pnas.1800562115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042100PMC
June 2018

Sample manipulation and data assembly for robust microcrystal synchrotron crystallography.

IUCrJ 2018 May 19;5(Pt 3):238-246. Epub 2018 Apr 19.

Photon Science Directorate, NSLS-II, Brookhaven National Laboratory, Upton, NY 11973, USA.

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http://dx.doi.org/10.1107/S2052252518005389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929371PMC
May 2018

Characterizing monoclonal antibody structure by carboxyl group footprinting.

MAbs 2015 ;7(3):540-52

a Center for Proteomics and Bioinformatics; School of Medicine; Case Western Reserve University ; Cleveland , OH , USA.

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http://dx.doi.org/10.1080/19420862.2015.1023683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622658PMC
March 2016

Crystallization of proteins from crude bovine rod outer segments.

Methods Enzymol 2015 17;557:439-58. Epub 2015 Mar 17.

Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA; Cleveland Center for Membrane and Structural Biology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2014.11.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486017PMC
February 2016

Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.

Nat Chem Biol 2015 Jun 20;11(6):409-15. Epub 2015 Apr 20.

Department of Pharmacology, Cleveland Center for Membrane and Structural Biology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1038/nchembio.1799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433804PMC
June 2015

High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules.

Protein Sci 2014 Nov 25;23(11):1629-39. Epub 2014 Sep 25.

Department of Pharmacology and Cleveland Center for Membrane and Structural Biology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106.

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http://dx.doi.org/10.1002/pro.2543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241113PMC
November 2014

Structural determinants of the 5'-methylthioinosine specificity of Plasmodium purine nucleoside phosphorylase.

PLoS One 2014 8;9(1):e84384. Epub 2014 Jan 8.

Departments of Medicine, Pathology, and of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084384PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885546PMC
September 2014

HIV-1 resistance to maraviroc conferred by a CD4 binding site mutation in the envelope glycoprotein gp120.

J Virol 2013 Jan 7;87(2):923-34. Epub 2012 Nov 7.

Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1128/JVI.01863-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554087PMC
January 2013

Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.

Proc Natl Acad Sci U S A 2012 Oct 24;109(41):E2747-56. Epub 2012 Sep 24.

Department of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1073/pnas.1212025109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478654PMC
October 2012

Characterization of metalloproteins by high-throughput X-ray absorption spectroscopy.

Genome Res 2011 Jun 11;21(6):898-907. Epub 2011 Apr 11.

New York SGX Research Center for Structural Genomics (NYSGXRC), Case Western Reserve University, Center for Proteomics and Bioinformatics, Case Center for Synchrotron Biosciences, Upton, New York 11973, USA.

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http://dx.doi.org/10.1101/gr.115097.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106322PMC
June 2011

Metalloproteomics: forward and reverse approaches in metalloprotein structural and functional characterization.

Curr Opin Chem Biol 2011 Feb 2;15(1):144-8. Epub 2010 Dec 2.

Center for Proteomics and Bioinformatics, Case Western Reserve University, 10900 Euclid Ave, BRB 113, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1016/j.cbpa.2010.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040278PMC
February 2011

Structural analysis of a highly glycosylated and unliganded gp120-based antigen using mass spectrometry.

Biochemistry 2010 Oct;49(42):9032-45

Center for Proteomics and Bioinformatics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi1011332
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http://dx.doi.org/10.1021/bi1011332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957511PMC
October 2010

Structural characterization of HIV gp41 with the membrane-proximal external region.

J Biol Chem 2010 Jul 4;285(31):24290-8. Epub 2010 Jun 4.

Center for Synchrotron Biosciences, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1074/jbc.M110.111351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911339PMC
July 2010

Four generations of transition-state analogues for human purine nucleoside phosphorylase.

Proc Natl Acad Sci U S A 2010 Mar 8;107(11):4805-12. Epub 2010 Mar 8.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0913439107
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http://dx.doi.org/10.1073/pnas.0913439107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841916PMC
March 2010

Neighboring group participation in the transition state of human purine nucleoside phosphorylase.

Biochemistry 2007 May 4;46(17):5038-49. Epub 2007 Apr 4.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1021/bi700147bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526054PMC
May 2007

A high-throughput approach to protein structure analysis.

Genet Eng (N Y) 2007 ;28:105-28

New York Structural GenomiX Research Consortium (NYSGXRC), Center for Synchrotron Biosciences, National Synchrotron Light Source, Brookhaven National Laboratory, Upton, NY 11973, USA.

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http://dx.doi.org/10.1007/978-0-387-34504-8_7DOI Listing
January 2007

Beamline X29: a novel undulator source for X-ray crystallography.

J Synchrotron Radiat 2006 Sep 12;13(Pt 5):365-72. Epub 2006 Aug 12.

Center for Synchrotron Biosciences, Case Proteomics Center, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1107/S0909049506027853DOI Listing
September 2006

The ybeY protein from Escherichia coli is a metalloprotein.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 Nov 20;61(Pt 11):959-63. Epub 2005 Oct 20.

New York Structural Genomics Research Consortium (NYSGXRC), Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1107/S1744309105031131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978141PMC
November 2005

Structure of the actin crosslinking core of fimbrin.

Structure 2004 Jun;12(6):999-1013

Department of Biochemistry, Center for Synchrotron Biosciences, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1016/j.str.2004.04.010DOI Listing
June 2004

Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.

J Biol Chem 2004 Apr 23;279(18):18103-6. Epub 2004 Feb 23.

Department of Biochemistry, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.C400068200
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http://dx.doi.org/10.1074/jbc.C400068200DOI Listing
April 2004

Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.

Biochemistry 2004 Jan;43(1):9-18

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1021/bi0358420DOI Listing
January 2004

Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.

Biochemistry 2003 May;42(20):6057-66

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1021/bi0343830DOI Listing
May 2003

Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.

Biochemistry 2002 Dec;41(49):14489-98

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1021/bi026636fDOI Listing
December 2002

Closed site complexes of adenine phosphoribosyltransferase from Giardia lamblia reveal a mechanism of ribosyl migration.

J Biol Chem 2002 Oct 8;277(42):39981-8. Epub 2002 Aug 8.

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1074/jbc.M205596200DOI Listing
October 2002