Wuguo Deng

Wuguo Deng

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Wuguo Deng

Publications by authors named "Wuguo Deng"

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Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.

Biochim Biophys Acta Mol Cell Res 2019 Oct 10;1866(10):1533-1543. Epub 2019 Jul 10.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2019.07.001DOI Listing
October 2019

Panobinostat (LBH589) inhibits Wnt/β-catenin signaling pathway via upregulating APCL expression in breast cancer.

Cell Signal 2019 Jul 14;59:62-75. Epub 2019 Mar 14.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2019.03.014DOI Listing
July 2019

TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.

Cancer Lett 2019 Jun 21;452:1-13. Epub 2019 Mar 21.

The Second Affiliated Hospital of Dalian Medical University, Dalian, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.03.017DOI Listing
June 2019

TFAP2B overexpression contributes to tumor growth and progression of thyroid cancer through the COX-2 signaling pathway.

Cell Death Dis 2019 May 21;10(6):397. Epub 2019 May 21.

Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center of Cancer Medicine, Guangzhou, Guangdong, China.

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http://dx.doi.org/10.1038/s41419-019-1600-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529436PMC
May 2019

Melatonin enhances sorafenib-induced cytotoxicity in FLT3-ITD acute myeloid leukemia cells by redox modification.

Theranostics 2019 31;9(13):3768-3779. Epub 2019 May 31.

Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.

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http://dx.doi.org/10.7150/thno.34327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587355PMC
May 2019

CDK4/6 inhibitor palbociclib enhances the effect of pyrotinib in HER2-positive breast cancer.

Cancer Lett 2019 Apr 21;447:130-140. Epub 2019 Jan 21.

Sun Yat-Sen University Cancer Center, The State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.01.005DOI Listing
April 2019

Sequence-dependent synergistic cytotoxicity of icotinib and pemetrexed in human lung cancer cell lines in vitro and in vivo.

J Exp Clin Cancer Res 2019 Apr 5;38(1):148. Epub 2019 Apr 5.

Department of Clinical Laboratory, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.

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http://dx.doi.org/10.1186/s13046-019-1133-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451286PMC
April 2019

Ku80 promotes melanoma growth and regulates antitumor effect of melatonin by targeting HIF1-α dependent PDK-1 signaling pathway.

Redox Biol 2019 Apr 20:101197. Epub 2019 Apr 20.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101197DOI Listing
April 2019

Melatonin inhibits MLL-rearranged leukemia via RBFOX3/hTERT and NF-κB/COX-2 signaling pathways.

Cancer Lett 2019 Feb 11;443:167-178. Epub 2018 Dec 11.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China; State Key Laboratory of Targeted Drug for Tumors of Guangdong Province, Guangzhou Double Bioproduct Inc., Guangzhou, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835183070
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http://dx.doi.org/10.1016/j.canlet.2018.11.037DOI Listing
February 2019

BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.

Redox Biol 2019 01 25;20:427-441. Epub 2018 Oct 25.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132317183065
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http://dx.doi.org/10.1016/j.redox.2018.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230923PMC
January 2019

Activator Protein-2β Promotes Tumor Growth and Predicts Poor Prognosis in Breast Cancer.

Cell Physiol Biochem 2018 4;47(5):1925-1935. Epub 2018 Jul 4.

Institute of Cancer Stem Cell & The Second Affiliated Hospital, Dalian Medical University, Dalian, China.

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http://dx.doi.org/10.1159/000491463DOI Listing
August 2018

RBFOX3 Regulates the Chemosensitivity of Cancer Cells to 5-Fluorouracil via the PI3K/AKT, EMT and Cytochrome-C/Caspase Pathways.

Cell Physiol Biochem 2018 18;46(4):1365-1380. Epub 2018 Apr 18.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

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http://dx.doi.org/10.1159/000489153DOI Listing
July 2018

RBFOX3 Promotes Tumor Growth and Progression via hTERT Signaling and Predicts a Poor Prognosis in Hepatocellular Carcinoma.

Theranostics 2017 22;7(12):3138-3154. Epub 2017 Jul 22.

Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

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http://dx.doi.org/10.7150/thno.19506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566111PMC
April 2018

MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation.

Mol Oncol 2018 03 13;12(3):391-405. Epub 2018 Feb 13.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

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http://dx.doi.org/10.1002/1878-0261.12173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830628PMC
March 2018

The Tumor-Promoting Role of TRIP4 in Melanoma Progression and its Involvement in Response to BRAF-Targeted Therapy.

J Invest Dermatol 2018 01 9;138(1):159-170. Epub 2017 Sep 9.

Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.07.850DOI Listing
January 2018

KLF4 overcomes tamoxifen resistance by suppressing MAPK signaling pathway and predicts good prognosis in breast cancer.

Cell Signal 2018 Jan 4;42:165-175. Epub 2017 Oct 4.

Department of Surgical Oncology, Sir Run Run Shaw Hospital, Zhejiang University, China. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2017.09.025DOI Listing
January 2018

β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.

Cell Physiol Biochem 2017 15;44(2):467-478. Epub 2017 Nov 15.

Institute of Cancer Stem Cell & The Second Affiliated Hospital, Dalian Medical University, Dalian, China.

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http://dx.doi.org/10.1159/000485013DOI Listing
January 2018

MLN4924 neddylation inhibitor promotes cell death in paclitaxel-resistant human lung adenocarcinoma cells.

Oncol Lett 2018 Jan 1;15(1):515-521. Epub 2017 Nov 1.

Institute of Cancer Stem Cell, Dalian Medical University Cancer Center, Dalian, Liaoning 116044, P.R. China.

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http://dx.doi.org/10.3892/ol.2017.7314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768125PMC
January 2018

XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.

PLoS One 2017 19;12(10):e0186900. Epub 2017 Oct 19.

SunYat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186900PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648251PMC
November 2017

Downregulation of NMI promotes tumor growth and predicts poor prognosis in human lung adenocarcinomas.

Mol Cancer 2017 10 12;16(1):158. Epub 2017 Oct 12.

Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

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http://dx.doi.org/10.1186/s12943-017-0705-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639741PMC
October 2017

PD-1 and PD-L1 expression in 132 recurrent nasopharyngeal carcinoma: the correlation with anemia and outcomes.

Oncotarget 2017 Aug 19;8(31):51210-51223. Epub 2017 Apr 19.

Hubei Key Laboratory of Tumor Biological Behaviors, Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.

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http://dx.doi.org/10.18632/oncotarget.17214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584243PMC
August 2017

Pleiotropic FTY720 Is a Specific and Potent Therapy for Hypertrophic Scars.

J Invest Dermatol 2017 07 10;137(7):1552-1561. Epub 2017 Mar 10.

Department of Burn and Plastic Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.02.978DOI Listing
July 2017

CDC5L Promotes hTERT Expression and Colorectal Tumor Growth.

Cell Physiol Biochem 2017 4;41(6):2475-2488. Epub 2017 May 4.

The First Affiliated Hospital and Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.

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http://dx.doi.org/10.1159/000475916DOI Listing
July 2017

KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway.

Cell Death Dis 2017 07 20;8(7):e2940. Epub 2017 Jul 20.

Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

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http://dx.doi.org/10.1038/cddis.2017.285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550845PMC
July 2017

Keratin 23 promotes telomerase reverse transcriptase expression and human colorectal cancer growth.

Cell Death Dis 2017 07 27;8(7):e2961. Epub 2017 Jul 27.

The First Affiliated Hospital and Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.

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http://dx.doi.org/10.1038/cddis.2017.339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550880PMC
July 2017

A wash-free SNAP-tag fluorogenic probe based on the additive effects of quencher release and environmental sensitivity.

Chem Commun (Camb) 2017 Jun;53(48):6448-6451

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

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http://dx.doi.org/10.1039/c7cc01483jDOI Listing
June 2017

NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer.

Cell Death Dis 2017 05 11;8(5):e2783. Epub 2017 May 11.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

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http://dx.doi.org/10.1038/cddis.2017.200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520720PMC
May 2017

S100A6 promotes cell proliferation in human nasopharyngeal carcinoma via the p38/MAPK signaling pathway.

Mol Carcinog 2017 03 27;56(3):972-984. Epub 2016 Sep 27.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.

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http://dx.doi.org/10.1002/mc.22563DOI Listing
March 2017

Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways.

J Pineal Res 2017 Mar 24;62(2). Epub 2016 Dec 24.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.

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http://dx.doi.org/10.1111/jpi.12380DOI Listing
March 2017

PD-L1 predicts poor prognosis for nasopharyngeal carcinoma irrespective of PD-1 and EBV-DNA load.

Sci Rep 2017 03 3;7:43627. Epub 2017 Mar 3.

Hubei Key Laboratory of Tumour Biological Behaviors, Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.

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http://dx.doi.org/10.1038/srep43627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335261PMC
March 2017

Bufalin Inhibits hTERT Expression and Colorectal Cancer Cell Growth by Targeting CPSF4.

Cell Physiol Biochem 2016 21;40(6):1559-1569. Epub 2016 Dec 21.

The First Affiliated Hospital & Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.

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http://dx.doi.org/10.1159/000453206DOI Listing
February 2017

Targeting NF-κB/AP-2β signaling to enhance antitumor activity of cisplatin by melatonin in hepatocellular carcinoma cells.

Am J Cancer Res 2017 1;7(1):13-27. Epub 2017 Jan 1.

Sun Yat-sen University Cancer Centre; State Key Laboratory of Oncology in South China; Collaborative Innovation Center of Cancer MedicineGuangzhou, China; State Key Laboratory of Targeted Drug for Tumors of Guangdong Province, Guangzhou Double Bioproduct Inc.Guangzhou, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250677PMC
January 2017

Cleavage and polyadenylation specific factor 4 targets NF-κB/cyclooxygenase-2 signaling to promote lung cancer growth and progression.

Cancer Lett 2016 10 20;381(1):1-13. Epub 2016 Jul 20.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China; State Key Laboratory of Targeted Drug for Tumors of Guangdong Province, Guangzhou Double Bioproduct Inc., Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.07.016DOI Listing
October 2016

Proteomics-based identification of VDAC1 as a tumor promoter in cervical carcinoma.

Oncotarget 2016 08;7(32):52317-52328

Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.

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http://dx.doi.org/10.18632/oncotarget.10562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239554PMC
August 2016

Outcomes of Induction Chemotherapy Plus Intensity-Modulated Radiotherapy (IMRT) Versus IMRT Plus Concurrent Chemotherapy for Locoregionally Advanced Nasopharyngeal Carcinoma: A Propensity Matched Study.

Transl Oncol 2016 Aug;9(4):329-35

Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2016.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006810PMC
August 2016

A genome-scale CRISPR-Cas9 screening method for protein stability reveals novel regulators of Cdc25A.

Cell Discov 2016 24;2:16014. Epub 2016 May 24.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China; Guangdong Provincial Key Laboratory of Tumor Targeted Drugs, Guangzhou Doublle Bioproducts Co. Ltd., Guangzhou, China.

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http://dx.doi.org/10.1038/celldisc.2016.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877570PMC
July 2016

Effect of intensity-modulated radiotherapy versus two-dimensional conventional radiotherapy alone in nasopharyngeal carcinoma.

Oncotarget 2016 May;7(22):33408-17

Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China.

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http://dx.doi.org/10.18632/oncotarget.8573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078105PMC
May 2016

High expression of Y-box-binding protein 1 correlates with poor prognosis and early recurrence in patients with small invasive lung adenocarcinoma.

Onco Targets Ther 2016 5;9:2683-92. Epub 2016 May 5.

The First Affiliated Hospital, Institute of Cancer Stem Cell, Lung Cancer Diagnosis and Treatment Center, Dalian Medical University, Dalian, People's Republic of China.

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https://www.dovepress.com/high-expression-of-y-box-binding-p
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http://dx.doi.org/10.2147/OTT.S99939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863593PMC
May 2016

hnRNPA2/B1 activates cyclooxygenase-2 and promotes tumor growth in human lung cancers.

Mol Oncol 2016 Apr 30;10(4):610-24. Epub 2015 Nov 30.

Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, PR China; State Key Laboratory of Targeted Drug for Tumors of Guangdong Province, Guangzhou Double Bioproduct Inc., Guangzhou, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423139PMC
April 2016

MED27 promotes melanoma growth by targeting AKT/MAPK and NF-κB/iNOS signaling pathways.

Cancer Lett 2016 Apr 18;373(1):77-87. Epub 2016 Jan 18.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China; State Key Laboratory of Targeted Drug for Tumors of Guangdong Province, Guangzhou Double Bioproduct Inc., Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.01.005DOI Listing
April 2016

Diabetes, prediabetes and the survival of nasopharyngeal carcinoma: a study of 5,860 patients.

PLoS One 2014 28;9(10):e111073. Epub 2014 Oct 28.

Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111073PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211733PMC
January 2016

Melatonin overcomes gemcitabine resistance in pancreatic ductal adenocarcinoma by abrogating nuclear factor-κB activation.

J Pineal Res 2016 Jan 17;60(1):27-38. Epub 2015 Oct 17.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.

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http://dx.doi.org/10.1111/jpi.12285DOI Listing
January 2016

Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells.

Oncotarget 2016 Jan;7(3):2985-3001

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

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http://dx.doi.org/10.18632/oncotarget.6407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823085PMC
January 2016

Propensity score matching analysis of cisplatin-based concurrent chemotherapy in low risk nasopharyngeal carcinoma in the intensity-modulated radiotherapy era.

Oncotarget 2015 Dec;6(41):44019-29

Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China.

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http://dx.doi.org/10.18632/oncotarget.5806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791283PMC
December 2015

Palbociclib inhibits epithelial-mesenchymal transition and metastasis in breast cancer via c-Jun/COX-2 signaling pathway.

Oncotarget 2015 Dec;6(39):41794-808

Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, China.

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http://dx.doi.org/10.18632/oncotarget.5993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747189PMC
December 2015

Melatonin enhances the anti-tumor effect of fisetin by inhibiting COX-2/iNOS and NF-κB/p300 signaling pathways.

PLoS One 2014 7;9(7):e99943. Epub 2014 Jul 7.

Institute of Cancer Stem Cell, Dalian Medical University Cancer Center, Dalian, China; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China; The First Affiliated Hospital, Dalian Medical University Cancer Center, Dalian, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099943PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085069PMC
November 2015

Expression and prognostic value of GalNAc-T3 in patients with completely resected small (≤2 cm) peripheral lung adenocarcinoma after IASLC/ATS/ERS classification.

Onco Targets Ther 2015 27;8:3143-52. Epub 2015 Oct 27.

Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China ; Lung Cancer Diagnosis and Treatment Center, Dalian, People's Republic of China.

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http://dx.doi.org/10.2147/OTT.S93486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629976PMC
November 2015

RPS3 regulates melanoma cell growth and apoptosis by targeting Cyto C/Ca2+/MICU1 dependent mitochondrial signaling.

Oncotarget 2015 Oct;6(30):29614-25

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

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http://dx.doi.org/10.18632/oncotarget.4868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745750PMC
October 2015

RFPL3 and CBP synergistically upregulate hTERT activity and promote lung cancer growth.

Oncotarget 2015 Sep;6(29):27130-45

The First Affiliated Hospital and Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.

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http://dx.doi.org/10.18632/oncotarget.4825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694978PMC
September 2015

Effusanin E suppresses nasopharyngeal carcinoma cell growth by inhibiting NF-κB and COX-2 signaling.

PLoS One 2014 21;9(10):e109951. Epub 2014 Oct 21.

State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109951PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204824PMC
June 2015

Activating enhancer-binding protein-2α induces cyclooxygenase-2 expression and promotes nasopharyngeal carcinoma growth.

Oncotarget 2015 Mar;6(7):5005-21

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467130PMC
http://dx.doi.org/10.18632/oncotarget.3215DOI Listing
March 2015

Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells.

Oncotarget 2014 Dec;5(23):11909-23

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China. State Key Laboratory of Targeted Drug for Tumors of Guangdong Province, Guangzhou Double Bioproduct Inc., Guangzhou, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322990PMC
http://dx.doi.org/10.18632/oncotarget.2557DOI Listing
December 2014

Melatonin attenuates hypoxic pulmonary hypertension by inhibiting the inflammation and the proliferation of pulmonary arterial smooth muscle cells.

J Pineal Res 2014 Nov 14;57(4):442-50. Epub 2014 Oct 14.

Institute of Cancer Stem Cell, The First Affiliated Hospital, Dalian Medical University Cancer Center, Dalian, China; Department of Anatomy, Qiqihar Medical University, Qiqihar, China.

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http://dx.doi.org/10.1111/jpi.12184DOI Listing
November 2014

Upregulation of cleavage and polyadenylation specific factor 4 in lung adenocarcinoma and its critical role for cancer cell survival and proliferation.

PLoS One 2013 16;8(12):e82728. Epub 2013 Dec 16.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China ; State Key Laboratory of Targeted Drug for Tumors of Guangdong Province, Guangzhou Double Bioproduct Inc., Guangzhou, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082728PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865097PMC
October 2014

Transcriptional coactivator CBP upregulates hTERT expression and tumor growth and predicts poor prognosis in human lung cancers.

Oncotarget 2014 Oct;5(19):9349-61

Institute of Cancer Stem Cell & First Affiliated Hospital, Dalian Medical University, Dalian, China. Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Colaborative Innovation Center of Cancer Medicine, Guangzhou, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253439PMC
http://dx.doi.org/10.18632/oncotarget.2430DOI Listing
October 2014

Combination of EGFR-TKIs and chemotherapy as first-line therapy for advanced NSCLC: a meta-analysis.

PLoS One 2013 13;8(11):e79000. Epub 2013 Nov 13.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China ; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079000PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827342PMC
September 2014

Friend leukemia virus integration 1 expression has prognostic significance in nasopharyngeal carcinoma.

Transl Oncol 2014 Aug;7(4):493-502

State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, China; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, China. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2014.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202802PMC
August 2014

Pharmacological modulation of autophagy enhances Newcastle disease virus-mediated oncolysis in drug-resistant lung cancer cells.

BMC Cancer 2014 Jul 30;14:551. Epub 2014 Jul 30.

Institute of Cancer Stem Cell, Dalian Medical University Cancer Center, 9 Lvshun Road South, Dalian 116044, China.

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http://dx.doi.org/10.1186/1471-2407-14-551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141091PMC
July 2014

Multicenter randomized phase 2 clinical trial of a recombinant human endostatin adenovirus in patients with advanced head and neck carcinoma.

Mol Ther 2014 Jun 25;22(6):1221-1229. Epub 2014 Mar 25.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Science, Beijing, China. Electronic address:

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http://dx.doi.org/10.1038/mt.2014.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048902PMC
June 2014

CPSF4 activates telomerase reverse transcriptase and predicts poor prognosis in human lung adenocarcinomas.

Mol Oncol 2014 May 14;8(3):704-16. Epub 2014 Feb 14.

Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China; State Key Laboratory of Targeted Drug for Tumors of Guangdong Province, Guangzhou Double Bioproduct Inc., Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2014.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528626PMC
May 2014

TFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK and VEGF/PEDF signaling.

Mol Cancer 2014 Apr 26;13:89. Epub 2014 Apr 26.

State Key Laboratory of Oncology in South China, Colaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, China.

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http://dx.doi.org/10.1186/1476-4598-13-89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021500PMC
April 2014

Lin28 mediates radiation resistance of breast cancer cells via regulation of caspase, H2A.X and Let-7 signaling.

PLoS One 2013 20;8(6):e67373. Epub 2013 Jun 20.

Key Laboratory of Biotherapy of Zhejiang Province, Department of Surgical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067373PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688678PMC
February 2014

TFAP2A regulates nasopharyngeal carcinoma growth and survival by targeting HIF-1α signaling pathway.

Cancer Prev Res (Phila) 2014 Feb 12;7(2):266-77. Epub 2013 Dec 12.

Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, China. and Wenlin Huang,

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http://dx.doi.org/10.1158/1940-6207.CAPR-13-0271DOI Listing
February 2014

Prognostic impact of cigarette smoking on the survival of patients with established nasopharyngeal carcinoma.

Cancer Epidemiol Biomarkers Prev 2013 Dec 19;22(12):2285-94. Epub 2013 Nov 19.

Authors' Affiliations: State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine; and Departments of Radiation Oncology and Epidemiology, Sun Yat-sen University Cancer Center, Guangzhou, China.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0546DOI Listing
December 2013

Small interfering RNA-based molecular therapy of cancers.

Chin J Cancer 2013 Sep 18;32(9):488-93. Epub 2013 Jan 18.

State Key Laboratory of Oncology in South China; Research Department, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P. R. China.

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http://dx.doi.org/10.5732/cjc.012.10280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845562PMC
September 2013

Melatonin potentiates the antiproliferative and pro-apoptotic effects of ursolic acid in colon cancer cells by modulating multiple signaling pathways.

J Pineal Res 2013 May 17;54(4):406-16. Epub 2013 Jan 17.

State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, China.

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http://dx.doi.org/10.1111/jpi.12035DOI Listing
May 2013

Lin28 mediates paclitaxel resistance by modulating p21, Rb and Let-7a miRNA in breast cancer cells.

PLoS One 2012 9;7(7):e40008. Epub 2012 Jul 9.

Department of Gastrointestinal Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040008PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392258PMC
March 2013

Identification of unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma by a large-scale synthetic lethal RNAi screening.

Pigment Cell Melanoma Res 2013 Jan 6;26(1):97-112. Epub 2012 Nov 6.

Department of Melanoma Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1111/pcmr.12031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919534PMC
January 2013

Melatonin suppresses proinflammatory mediators in lipopolysaccharide-stimulated CRL1999 cells via targeting MAPK, NF-κB, c/EBPβ, and p300 signaling.

J Pineal Res 2012 Sep 21;53(2):154-65. Epub 2012 Feb 21.

State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, China.

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http://dx.doi.org/10.1111/j.1600-079X.2012.00982.xDOI Listing
September 2012

Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells.

J Pineal Res 2012 Aug 16;53(1):77-90. Epub 2012 Feb 16.

State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, China.

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http://dx.doi.org/10.1111/j.1600-079X.2012.00973.xDOI Listing
August 2012

Quercetin suppresses cyclooxygenase-2 expression and angiogenesis through inactivation of P300 signaling.

PLoS One 2011 8;6(8):e22934. Epub 2011 Aug 8.

State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022934PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152552PMC
February 2012

Tumor suppressor 101F6 and ascorbate synergistically and selectively inhibit non-small cell lung cancer growth by caspase-independent apoptosis and autophagy.

Cancer Res 2007 Jul;67(13):6293-303

Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3884DOI Listing
July 2007