Publications by authors named "Wouter W Wiegant"

29Publications

Functional Analysis of Missense Variants in the Putative Breast Cancer Susceptibility Gene XRCC2.

Hum Mutat 2016 09 17;37(9):914-25. Epub 2016 Jun 17.

Department of Human Genetics, Leiden University Medical Center, Leiden, 2300, RC, The Netherlands.

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http://dx.doi.org/10.1002/humu.23019DOI Listing
September 2016

The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.

Nucleic Acids Res 2016 Apr 15;44(6):2976. Epub 2015 Dec 15.

Department of Human Genetics, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands

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http://dx.doi.org/10.1093/nar/gkv1480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824094PMC
April 2016

The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.

Nucleic Acids Res 2015 Aug 22;43(14):6919-33. Epub 2015 Jun 22.

Department of Human Genetics, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands

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http://dx.doi.org/10.1093/nar/gkv613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538816PMC
August 2015

Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling.

J Cell Sci 2013 Feb 21;126(Pt 4):889-903. Epub 2012 Dec 21.

Department of Toxicogenetics, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.

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http://dx.doi.org/10.1242/jcs.109413DOI Listing
February 2013

The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection.

Nature 2012 Sep 9;489(7417):581-4. Epub 2012 Sep 9.

Department of Toxicogenetics, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands.

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http://dx.doi.org/10.1038/nature11353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493121PMC
September 2012

The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage.

J Cell Biol 2010 Sep 30;190(5):741-9. Epub 2010 Aug 30.

Department of Toxicogenetics, Leiden University Medical Center, Leiden 2300RC, Netherlands.

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http://dx.doi.org/10.1083/jcb.201001048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935570PMC
September 2010

Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions.

Proc Natl Acad Sci U S A 2006 Jun 26;103(23):8768-73. Epub 2006 May 26.

Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1073/pnas.0600298103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1482653PMC
June 2006

Chinese hamster cell mutant, V-C8, a model for analysis of Brca2 function.

Mutat Res 2006 Aug 27;600(1-2):79-88. Epub 2006 Apr 27.

Department of Toxicogenetics, Leiden University Medical Center, Einthovenweg 20, Postzone S-6-P, P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.mrfmmm.2006.03.001DOI Listing
August 2006

Inducibility of nuclear Rad51 foci after DNA damage distinguishes all Fanconi anemia complementation groups from D1/BRCA2.

Mutat Res 2006 Feb 8;594(1-2):39-48. Epub 2005 Sep 8.

Department of Toxicogenetics, Leiden University Medical Center, Wassenaarseweg 72, NL-2333 AL Leiden, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S002751070500378
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http://dx.doi.org/10.1016/j.mrfmmm.2005.07.008DOI Listing
February 2006

The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J.

Nat Genet 2005 Sep 21;37(9):934-5. Epub 2005 Aug 21.

Department of Clinical Genetics and Human Genetics, VU University Medical Center, Van der Boechorststraat 7, NL-1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng1625DOI Listing
September 2005

Brca2 (XRCC11) deficiency results in enhanced mutagenesis.

Mutagenesis 2003 Nov;18(6):521-5

Department of Toxicogenetics-MGC, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/mutage/geg032DOI Listing
November 2003

Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability.

Nucleic Acids Res 2002 May;30(10):2172-82

Department of Radiation Genetics and Chemical Mutagenesis, Leiden University Medical Center, Wassenaarseweg 72, 2333 AL, Leiden, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC115287PMC
http://dx.doi.org/10.1093/nar/30.10.2172DOI Listing
May 2002