Publications by authors named "Wouter R Karthaus"

20Publications

Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses.

J Vis Exp 2019 10 24(152). Epub 2019 Oct 24.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center;

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October 2019

Strategies to Identify and Target Cells of Origin in Prostate Cancer.

J Natl Cancer Inst 2019 03;111(3):221-223

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York, USA.

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March 2019

Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon.

Proc Natl Acad Sci U S A 2016 09 29;113(37):E5399-407. Epub 2016 Aug 29.

Hubrecht Institute for Developmental Biology and Stem Cell Research, 3584 CT, Utrecht, The Netherlands; Cancer Genomics Netherlands, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands;

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September 2016

Organoid culture systems for prostate epithelial and cancer tissue.

Nat Protoc 2016 Feb 21;11(2):347-58. Epub 2016 Jan 21.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Utrecht, the Netherlands.

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February 2016

Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors.

Cell Rep 2015 Dec 25;13(10):2147-58. Epub 2015 Nov 25.

Laboratory of Genitourinary Cancer Pathogenesis, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA. Electronic address:

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December 2015

Efficient intracellular delivery of native proteins.

Cell 2015 Apr;161(3):674-690

KNAW-Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands; University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, the Netherlands. Electronic address:

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April 2015

Organoid cultures derived from patients with advanced prostate cancer.

Cell 2014 Sep 4;159(1):176-187. Epub 2014 Sep 4.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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September 2014

Identification of multipotent luminal progenitor cells in human prostate organoid cultures.

Cell 2014 Sep 4;159(1):163-175. Epub 2014 Sep 4.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, 3584 CT, Utrecht, Netherlands. Electronic address:

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September 2014

Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ.

J Exp Med 2014 Jun;211(7):1393-405

Hubrecht Institute for Developmental Biology and Stem Cell Research and University Medical Centre Utrecht, 3584 CT Utrecht, Netherlands

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June 2014