Wouter A van der Linden

Wouter A van der Linden

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Wouter A van der Linden

Wouter A van der Linden

Publications by authors named "Wouter A van der Linden"

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31Publications

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Development of an activity-based probe for acyl-protein thioesterases.

PLoS One 2018 24;13(1):e0190255. Epub 2018 Jan 24.

Cancer Biology Program, Stanford University School of Medicine, Stanford, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190255PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783350PMC
February 2018

Legumain is activated in macrophages during pancreatitis.

Am J Physiol Gastrointest Liver Physiol 2016 09 11;311(3):G548-60. Epub 2016 Aug 11.

Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia; Department of Pharmacology, University of Melbourne, Parkville, Victoria, Australia; and ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, Victoria, Australia.

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http://www.physiology.org/doi/10.1152/ajpgi.00047.2016
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http://dx.doi.org/10.1152/ajpgi.00047.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075999PMC
September 2016

Bifunctional Probes of Cathepsin Protease Activity and pH Reveal Alterations in Endolysosomal pH during Bacterial Infection.

Cell Chem Biol 2016 07 14;23(7):793-804. Epub 2016 Jul 14.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2016.05.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982764PMC
July 2016

Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death.

Elife 2016 Mar 24;5:e13663. Epub 2016 Mar 24.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, United States.

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http://dx.doi.org/10.7554/eLife.13663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846378PMC
March 2016

Cysteine Cathepsin Inhibitors as Anti-Ebola Agents.

ACS Infect Dis 2016 Mar 20;2(3):173-179. Epub 2016 Jan 20.

Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305, United States.

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http://dx.doi.org/10.1021/acsinfecdis.5b00130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918641PMC
March 2016

The novel β2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells.

Haematologica 2015 Oct 11;100(10):1350-60. Epub 2015 Jun 11.

Experimental Oncology and Hematology, Department of Oncology and Hematology, Kantonsspital St.Gallen, Switzerland Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, the Netherlands

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http://dx.doi.org/10.3324/haematol.2014.109421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591768PMC
October 2015

Global Analysis of Palmitoylated Proteins in Toxoplasma gondii.

Cell Host Microbe 2015 Oct;18(4):501-11

Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://www.cell.com/cell-host-microbe/pdf/S1931-3128(15)0037
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http://linkinghub.elsevier.com/retrieve/pii/S193131281500375
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http://dx.doi.org/10.1016/j.chom.2015.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694575PMC
October 2015

Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2.

Mol Cell Proteomics 2015 Aug 3;14(8):2177-93. Epub 2015 Jun 3.

From the ‡Department of Cell Biology and Histology, Academic Medical Centre- University of Amsterdam, Meibergdreef 15, 1105AZ Amsterdam, The Netherlands;

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http://dx.doi.org/10.1074/mcp.M114.043331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528246PMC
August 2015

Design and Synthesis of Activity-Based Probes and Inhibitors for Bleomycin Hydrolase.

Chem Biol 2015 Aug 6;22(8):995-1001. Epub 2015 Aug 6.

Departments of Pathology and Microbiology and Immunology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2015.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546515PMC
August 2015

Detection of intestinal cancer by local, topical application of a quenched fluorescence probe for cysteine cathepsins.

Chem Biol 2015 Jan 8;22(1):148-58. Epub 2015 Jan 8.

Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2014.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353655PMC
January 2015

Assessing subunit dependency of the Plasmodium proteasome using small molecule inhibitors and active site probes.

ACS Chem Biol 2014 Aug 19;9(8):1869-76. Epub 2014 Jun 19.

Department of Chemical and Systems Biology and ‡Department of Pathology, Stanford University School of Medicine , 300 Pasteur Drive, Stanford, California 94305-5324, United States.

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http://dx.doi.org/10.1021/cb5001263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136710PMC
August 2014

Improved quenched fluorescent probe for imaging of cysteine cathepsin activity.

J Am Chem Soc 2013 Oct 19;135(39):14726-30. Epub 2013 Sep 19.

Departments of †Pathology, ‡Cancer Biology Program, and §Microbiology and Immunology, Stanford School of Medicine , 300 Pasteur Drive, Stanford, California 94305-5324, United States.

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http://dx.doi.org/10.1021/ja4056068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826460PMC
October 2013

Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS.

Nat Protoc 2013 Jun 23;8(6):1155-68. Epub 2013 May 23.

Gorlaeus Laboratories, Leiden Institute of Chemistry and Netherlands Proteomics Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/nprot.2013.065DOI Listing
June 2013

Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: a comparative study.

Bioorg Med Chem 2012 Jan 23;20(2):662-6. Epub 2011 Jun 23.

Leiden Institute of Chemistry and Netherlands Proteomics Centre, PO Box 9502, 2300 RA, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.bmc.2011.06.037DOI Listing
January 2012

Proteasome inhibitors: an expanding army attacking a unique target.

Chem Biol 2012 Jan;19(1):99-115

Department of Pharmacology and Toxicology, Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.1016/j.chembiol.2012.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503453PMC
January 2012

Bioorthogonal chemistry: applications in activity-based protein profiling.

Acc Chem Res 2011 Sep 28;44(9):718-29. Epub 2011 Jul 28.

Leiden Institute of Chemistry and The Netherlands Proteomics Centre, Einsteinweg 55, 2300 RA Leiden, The Netherlands.

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http://pubs.acs.org/doi/abs/10.1021/ar200125k
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http://dx.doi.org/10.1021/ar200125kDOI Listing
September 2011

A panel of subunit-selective activity-based proteasome probes.

Org Biomol Chem 2010 Jun 6;8(12):2719-27. Epub 2010 May 6.

Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands.

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http://dx.doi.org/10.1039/c001036gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042124PMC
June 2010

Proteasome selectivity towards Michael acceptor containing oligopeptide-based inhibitors.

Org Biomol Chem 2010 Apr;8(8):1885-93

Leiden Institute of Chemistry and Netherlands Proteomics Centre, P.O. Box 9502, 2300 RA, Leiden, The Netherlands.

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http://dx.doi.org/10.1039/b924134eDOI Listing
April 2010

Mixing of peptides and electrophilic traps gives rise to potent, broad-spectrum proteasome inhibitors.

Org Biomol Chem 2007 May 23;5(9):1416-26. Epub 2007 Mar 23.

Bio-organic synthesis, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300 RA, Leiden, The Netherlands.

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http://dx.doi.org/10.1039/b702268aDOI Listing
May 2007