Publications by authors named "Won Kon Kim"

57Publications

GADD45β Regulates Hepatic Gluconeogenesis via Modulating the Protein Stability of FoxO1.

Biomedicines 2021 Jan 8;9(1). Epub 2021 Jan 8.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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January 2021

Molecular Analysis of the Interaction between Human PTPN21 and the Oncoprotein E7 from Human Papillomavirus Genotype 18.

Mol Cells 2021 Jan 12. Epub 2021 Jan 12.

Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.

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January 2021

Myonectin inhibits adipogenesis in 3T3-L1 preadipocytes by regulating p38 MAPK pathway.

BMB Rep 2021 Jan 7. Epub 2021 Jan 7.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.

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January 2021

The transcription factor PITX1 drives astrocyte differentiation by regulating the SOX9 gene.

J Biol Chem 2020 Sep 5;295(39):13677-13690. Epub 2020 Aug 5.

Biodefence Research Center, Korea Research Institute of Bioscience and Biotechnology, Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea

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September 2020

Nurr1 performs its anti-inflammatory function by regulating RasGRP1 expression in neuro-inflammation.

Sci Rep 2020 07 1;10(1):10755. Epub 2020 Jul 1.

Biodefense Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, Republic of Korea.

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July 2020

GATA3 induces the upregulation of UCP-1 by directly binding to PGC-1α during adipose tissue browning.

Metabolism 2020 08 28;109:154280. Epub 2020 May 28.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon 34141, Republic of Korea. Electronic address:

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August 2020

IDH1-dependent α-KG regulates brown fat differentiation and function by modulating histone methylation.

Metabolism 2020 04 5;105:154173. Epub 2020 Feb 5.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon 34141, Republic of Korea. Electronic address:

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April 2020

Rapid differentiation of astrocytes from human embryonic stem cells.

Neurosci Lett 2020 01 10;716:134681. Epub 2019 Dec 10.

Research Center for Biodefence, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon, Republic of Korea. Electronic address:

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January 2020

Roles of Protein Histidine Phosphatase 1 (PHPT1) in Brown Adipocyte Differentiation.

J Microbiol Biotechnol 2020 Feb;30(2):306-312

Metabolic Regulation Research Center, KRIBB, Daejeon 34141, Republic of Korea.

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February 2020

The Latest Insights into Adipokines in Diabetes.

J Clin Med 2019 Nov 5;8(11). Epub 2019 Nov 5.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.

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November 2019

A reliable approach for assessing size-dependent effects of silica nanoparticles on cellular internalization behavior and cytotoxic mechanisms.

Int J Nanomedicine 2019 10;14:7375-7387. Epub 2019 Sep 10.

Division of Biomedical Research, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.

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January 2020

The Role of Adipose Tissue Mitochondria: Regulation of Mitochondrial Function for the Treatment of Metabolic Diseases.

Int J Mol Sci 2019 Oct 4;20(19). Epub 2019 Oct 4.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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October 2019

Protein Tyrosine Phosphatase, Receptor Type B (PTPRB) Inhibits Brown Adipocyte Differentiation through Regulation of VEGFR2 Phosphorylation.

J Microbiol Biotechnol 2019 Apr;29(4):645-650

Metabolic Regulation Research Center, Division of BioMedical Sciences, KRIBB, Daejeon 34141, Republic of Korea.

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April 2019

Two distinct cellular pathways leading to endothelial cell cytotoxicity by silica nanoparticle size.

J Nanobiotechnology 2019 Feb 5;17(1):24. Epub 2019 Feb 5.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.

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February 2019

Ginkgetin, a biflavone from Ginkgo biloba leaves, prevents adipogenesis through STAT5-mediated PPARγ and C/EBPα regulation.

Pharmacol Res 2019 01 22;139:325-336. Epub 2018 Nov 22.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, Republic of Korea; Department of Biomolecular Science, University of Science & Technology (UST), Daejeon, Republic of Korea. Electronic address:

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January 2019

HDAC11 Inhibits Myoblast Differentiation through Repression of MyoD-Dependent Transcription.

Mol Cells 2017 Sep 20;40(9):667-676. Epub 2017 Sep 20.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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September 2017

Phosphorylation of p53 at threonine 155 is required for Jab1-mediated nuclear export of p53.

BMB Rep 2017 Jul;50(7):373-378

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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July 2017

Metabolic Adaptation in Obesity and Type II Diabetes: Myokines, Adipokines and Hepatokines.

Int J Mol Sci 2016 Dec 22;18(1). Epub 2016 Dec 22.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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December 2016

Methyltransferase and demethylase profiling studies during brown adipocyte differentiation.

BMB Rep 2016 Jul;49(7):388-93

Metabolic Regulation Research Center, KRIBB; Department of Functional Genomics, University of Science and Technology (UST), Daejeon 34141, Korea.

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July 2016

Set7/9, a methyltransferase, regulates the thermogenic program during brown adipocyte differentiation through the modulation of p53 acetylation.

Mol Cell Endocrinol 2016 08 29;431:46-53. Epub 2016 Apr 29.

Metabolic Regulation Research Center, Division of BioMedical Sciences, KRIBB, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon 305-806, Republic of Korea. Electronic address:

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August 2016

High-performance dendritic contrast agents for X-ray computed tomography imaging using potent tetraiodobenzene derivatives.

J Control Release 2016 Mar 23;226:258-67. Epub 2016 Jan 23.

Biomedical Translational Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea; Korea University of Science and Technology (UST), Daejeon 305-350, Republic of Korea. Electronic address:

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March 2016

Profiling analysis of protein tyrosine phosphatases during neuronal differentiation.

Neurosci Lett 2016 Jan 15;612:219-224. Epub 2015 Dec 15.

Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon, Republic of Korea. Electronic address:

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January 2016

c-Jun regulates adipocyte differentiation via the KLF15-mediated mode.

Biochem Biophys Res Commun 2016 01 13;469(3):552-8. Epub 2015 Dec 13.

Functional Genomics Research Center, KRIBB, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST), Daejeon 305-806, Republic of Korea. Electronic address:

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January 2016

Phosphoprotein phosphatase 1CB (PPP1CB), a novel adipogenic activator, promotes 3T3-L1 adipogenesis.

Biochem Biophys Res Commun 2015 Nov 9;467(2):211-7. Epub 2015 Oct 9.

Research Institute of Biomolecular Chemistry, Dongguk University, Seoul 100-715, Republic of Korea. Electronic address:

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November 2015

MAP kinase phosphatase 3 inhibits brown adipocyte differentiation via regulation of Erk phosphorylation.

Mol Cell Endocrinol 2015 Nov 29;416:70-6. Epub 2015 Aug 29.

Functional Genomics Research Center, KRIBB, Daejeon, 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology of Korea, Daejeon, 305-806, Republic of Korea. Electronic address:

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November 2015

Stimulation of angiogenesis and survival of endothelial cells by human monoclonal Tie2 receptor antibody.

Biomaterials 2015 May 17;51:119-128. Epub 2015 Feb 17.

Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

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May 2015

Recent advances in proteomic studies of adipose tissues and adipocytes.

Int J Mol Sci 2015 Feb 27;16(3):4581-99. Epub 2015 Feb 27.

Functional Genomics Research Center, KRIBB, Daejeon 305-806, Korea.

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February 2015

DUSP4 regulates neuronal differentiation and calcium homeostasis by modulating ERK1/2 phosphorylation.

Stem Cells Dev 2015 Mar 23;24(6):686-700. Epub 2014 Dec 23.

1 Department of Biological Sciences, Center for Stem Cell Differentiation, KAIST , Daejeon, Republic of Korea.

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March 2015

Identification of DNA aptamers toward epithelial cell adhesion molecule via cell-SELEX.

Mol Cells 2014 Oct 29;37(10):742-6. Epub 2014 Sep 29.

Research Center for Integrated Cellulomics, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Korea ; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon 305-806, Korea.

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October 2014

Selection of aptamers for mature white adipocytes by cell SELEX using flow cytometry.

PLoS One 2014 20;9(5):e97747. Epub 2014 May 20.

Research Center for Integrated Cellulomics, KRIBB, Daejeon, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon, Republic of Korea.

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January 2015

Proteomic analysis of the effect of retinoic acids on the human breast cancer cell line MCF-7.

Mol Biol Rep 2014 May 11;41(5):3499-507. Epub 2014 Mar 11.

Research Center for Integrated Cellulomics, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 305-806, Korea.

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May 2014

Distinction of white, beige and brown adipocytes derived from mesenchymal stem cells.

World J Stem Cells 2014 Jan;6(1):33-42

Anna Park, Won Kon Kim, Kwang-Hee Bae, Research Center for Integrated Cellulomics, KRIBB, Daejeon 305-806, South Korea.

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January 2014

Protein tyrosine phosphatase profiling studies during brown adipogenic differentiation of mouse primary brown preadipocytes.

BMB Rep 2013 Nov;46(11):539-43

Research Center for Integrated Cellulomics, KRIBB; Department of Functional Genomics, University of Science and Technology (UST), Daejeon 305-806, Korea

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November 2013

Acceleration of adipogenic differentiation via acetylation of malate dehydrogenase 2.

Biochem Biophys Res Commun 2013 Nov 14;441(1):77-82. Epub 2013 Oct 14.

Research Center for Integrated Cellulomics, KRIBB, Daejeon 305-806, South Korea.

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November 2013

Investigation of adipocyte proteome during the differentiation of brown preadipocytes.

J Proteomics 2013 Dec 12;94:327-36. Epub 2013 Oct 12.

Research Center for Integrated Cellulomics, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-806, Republic of Korea.

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December 2013

Retinoic acid inhibits adipogenesis via activation of Wnt signaling pathway in 3T3-L1 preadipocytes.

Biochem Biophys Res Commun 2013 May 10;434(3):455-9. Epub 2013 Apr 10.

Department of Medical System Engineering, Gwangju Institute of Science and Technology, 123 Cheomdan-gwagiro, Buk-gu, Gwangju 500-712, Republic of Korea.

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May 2013

Involvement of protein tyrosine phosphatases in adipogenesis: new anti-obesity targets?

BMB Rep 2012 Dec;45(12):700-6

Medical Proteomics Research Center, KRIBB, Daejeon 305-806, Korea.

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December 2012

Myostatin inhibits brown adipocyte differentiation via regulation of Smad3-mediated β-catenin stabilization.

Int J Biochem Cell Biol 2012 Feb 11;44(2):327-34. Epub 2011 Nov 11.

Medical Proteomics Research Center, KRIBB, Daejeon 305-806, Republic of Korea.

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February 2012

RPTPμ tyrosine phosphatase promotes adipogenic differentiation via modulation of p120 catenin phosphorylation.

Mol Biol Cell 2011 Dec 12;22(24):4883-91. Epub 2011 Oct 12.

Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea.

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December 2011

Differential signatures of protein glycosylation and phosphorylation in human Chang liver cells induced by TCDD treatment.

Toxicol Lett 2008 Apr 15;178(1):20-8. Epub 2008 Feb 15.

Translational Research Center, KRIBB, 52 Eoeun-dong, Yuseong, Daejeon 305-806, Republic of Korea.

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April 2008

Quantitative relationship of dioxin-responsive gene expression to dioxin response element in Hep3B and HepG2 human hepatocarcinoma cell lines.

Toxicol Lett 2006 Aug 18;165(2):174-81. Epub 2006 Apr 18.

Systemic Proteomics Research Center, Korea Research Institute of Bioscience and BioTechnology (KRIBB), Daejeon, South Korea.

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August 2006