Publications by authors named "Wolfram Ruf"

153Publications

Metabolic and inflammatory reprogramming of macrophages by ONC201 translates in a pro-inflammatory environment even in presence of glioblastoma cells.

Authors:

Carsten Geiß Claudius Witzler Gernot Poschet Wolfram Ruf Anne Régnier-Vigouroux

Eur J Immunol 2021 Jan 13. Epub 2021 Jan 13.

Institute of Developmental Biology and Neurobiology, Johannes Gutenberg University, Mainz, Germany.

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January 2021

Immunomodulatory role of reactive oxygen species and nitrogen species during T cell-driven neutrophil-enriched acute and chronic cutaneous delayed-type hypersensitivity reactions.

Authors:

Roman Mehling Johannes Schwenck Christina Lemberg Christoph Trautwein Laimdota Zizmare Daniela Kramer Anne Müller Birgit Fehrenbacher Irene Gonzalez-Menendez Leticia Quintanilla-Martinez Katrin Schröder Ralph P Brandes Martin Schaller Wolfram Ruf Martin Eichner Kamran Ghoreschi Martin Röcken Bernd J Pichler Manfred Kneilling

Theranostics 2021 1;11(2):470-490. Epub 2021 Jan 1.

Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University, Tübingen, Germany.

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January 2021

Platelet-derived calpain cleaves the endothelial protease-activated receptor 1 to induce vascular inflammation in diabetes.

Authors:

Anastasia Kyselova Amro Elgheznawy Ilka Wittig Juliana Heidler Alexander W Mann Wolfram Ruf Ingrid Fleming Voahanginirina Randriamboavonjy

Basic Res Cardiol 2020 12 1;115(6):75. Epub 2020 Dec 1.

Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Theodor-Stern-Kai 7, 60596, Frankfurt am Main, Germany.

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December 2020

Procoagulant activities of skeletal muscle and cardiac myosins require both myosin protein and myosin-associated anionic phospholipids.

Authors:

Shravan Morla Hiroshi Deguchi José A Fernández Wolfram Ruf Rolf Andrew Brekken John H Griffin

Blood 2020 Nov 24. Epub 2020 Nov 24.

University of California, San Diego, United States.

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November 2020

Macrophage protease-activated receptor 2 regulates fetal liver erythropoiesis in mice.

Authors:

Mona Saffarzadeh Kristin Grunz T Son Nguyen Young K Lee Maki Kitano Sven Danckwardt Carina D S Rodrigues Hartmut Weiler Sabine Reyda Wolfram Ruf

Blood Adv 2020 Nov;4(22):5810-5824

Center for Thrombosis and Hemostasis, Johannes Gutenberg University Medical Center, Mainz, Germany.

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November 2020

Course of D-Dimer and C-Reactive Protein Levels in Survivors and Nonsurvivors with COVID-19 Pneumonia: A Retrospective Analysis of 577 Patients.

Authors:

Luca Valerio Paola Ferrazzi Clara Sacco Wolfram Ruf Nils Kucher Stavros V Konstantinides Stefano Barco Corrado Lodigiani

Thromb Haemost 2021 01 19;121(1):98-101. Epub 2020 Nov 19.

Center for Thrombosis and Hemorrhagic Diseases, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.

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January 2021

Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality.

Haematologica 2020 10 1;105(10):2484-2495. Epub 2020 Oct 1.

Department of Cardiology, University Heart Center, University Hospital, Zurich, Switzerland.

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October 2020

Characterization of Thrombin Generation Curve Shape in Presence of Platelets from Acute Venous Thromboembolism Patients.

Authors:

Jeremy Lagrange Bianca Wagner Markus Nagler Vincent Ten Cate Alejandro Pallares Robles Thomas Koeck Steffen Rapp Jürgen H Prochaska Henri M Spronk Philip Wenzel Wolfram Ruf Hugo Ten Cate Philipp S Wild Marina Panova-Noeva

J Clin Med 2020 Sep 7;9(9). Epub 2020 Sep 7.

Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.

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September 2020

Coagulation signaling and cancer immunotherapy.

Authors:

Wolfram Ruf Claudine Graf

Thromb Res 2020 07;191 Suppl 1:S106-S111

Center for Thrombosis and Hemostasis, Johannes Gutenberg University Medical Center, Mainz, Germany.

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July 2020

Podocyte Integrin- and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy.

J Am Soc Nephrol 2020 08 24;31(8):1762-1780. Epub 2020 Jul 24.

Institute of Clinical Chemistry and Pathobiochemistry, Otto von Guericke University Magdeburg, Magdeburg, Germany

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August 2020

Angiotensin II Infusion Leads to Aortic Dissection in LRP8 Deficient Mice.

Authors:

Jeremy Lagrange Stefanie Finger Sabine Kossmann Venkata Garlapati Wolfram Ruf Philip Wenzel

Int J Mol Sci 2020 Jul 12;21(14). Epub 2020 Jul 12.

Center for Thrombosis and Hemostasis, University Medical Center Mainz, 55131 Mainz, Germany.

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July 2020

Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice.

Authors:

Klytaimnistra Kiouptsi Giulia Pontarollo Hristo Todorov Johannes Braun Sven Jäckel Thomas Koeck Franziska Bayer Cornelia Karwot Angelica Karpi Susanne Gerber Yvonne Jansen Philipp Wild Wolfram Ruf Andreas Daiber Emiel Van Der Vorst Christian Weber Yvonne Döring Christoph Reinhardt

Gut Microbes 2020 Nov 24;11(6):1809-1823. Epub 2020 Jun 24.

Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz , Mainz, Germany.

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November 2020

TRIF turns the switch for DIC in sepsis.

Authors:

Wolfram Ruf

Blood 2020 04;135(14):1073-1074

Johannes Gutenberg University Medical Center Mainz.

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April 2020

Nox2+ myeloid cells drive vascular inflammation and endothelial dysfunction in heart failure after myocardial infarction via angiotensin II receptor type 1.

Authors:

Michael Molitor Wolf-Stephan Rudi Venkata Garlapati Stefanie Finger Rebecca Schüler Sabine Kossmann Jeremy Lagrange Thanh Son Nguyen Johannes Wild Tanja Knopp Susanne H Karbach Maike Knorr Wolfram Ruf Thomas Münzel Philip Wenzel

Cardiovasc Res 2021 Jan;117(1):162-177

Center for Thrombosis and Haemostasis, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany.

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January 2021

Vascular miR-181b controls tissue factor-dependent thrombogenicity and inflammation in type 2 diabetes.

Authors:

Marco Witkowski Mario Witkowski Mona Saffarzadeh Julian Friebel Termeh Tabaraie Loc Ta Bao Aritra Chakraborty Andrea Dörner Bernd Stratmann Diethelm Tschoepe Samantha J Winter Andreas Krueger Wolfram Ruf Ulf Landmesser Ursula Rauch

Cardiovasc Diabetol 2020 02 17;19(1):20. Epub 2020 Feb 17.

Charité Centrum 11, Department of Cardiology, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany.

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February 2020

Neutrophil extracellular traps impair fungal clearance in a mouse model of invasive pulmonary aspergillosis.

Authors:

Astrid Alflen Pamela Aranda Lopez Ann-Kathrin Hartmann Joachim Maxeiner Markus Bosmann Arjun Sharma Johannes Platten Frederic Ries Hendrik Beckert Wolfram Ruf Markus P Radsak

Immunobiology 2020 01 13;225(1):151867. Epub 2019 Nov 13.

Department of Internal Medicine III, University Medical Center of the Johannes Gutenberg University, Mainz, Germany. Electronic address:

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January 2020

Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension.

Authors:

Johanna Helmstädter Katie Frenis Konstantina Filippou Alexandra Grill Mobin Dib Sanela Kalinovic Franziska Pawelke Kamil Kus Swenja Kröller-Schön Matthias Oelze Stefan Chlopicki Detlef Schuppan Philip Wenzel Wolfram Ruf Daniel J Drucker Thomas Münzel Andreas Daiber Sebastian Steven

Arterioscler Thromb Vasc Biol 2020 01 21;40(1):145-158. Epub 2019 Nov 21.

From the Center for Cardiology (J.H., K. Frenis, K. Filippou, M.D., S.K., F.P., S.K.-S., M.O., P.W. T.M., A.D., S.S.), University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.

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January 2020

Rivaroxaban Effects Illustrate the Underestimated Importance of Activated Platelets in Thrombin Generation Assessed by Calibrated Automated Thrombography.

Authors:

Stephanie Makhoul Marina Panova-Noeva Véronique Regnault Wolfram Ruf Philip Wenzel Jeremy Lagrange

J Clin Med 2019 Nov 15;8(11). Epub 2019 Nov 15.

Center for Thrombosis and Hemostasis, University Medical Center Mainz, 55131 Mainz, Germany.

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November 2019

Myeloid cell-synthesized coagulation factor X dampens antitumor immunity.

Authors:

Claudine Graf Petra Wilgenbus Sven Pagel Jennifer Pott Federico Marini Sabine Reyda Maki Kitano Stephan Macher-Göppinger Hartmut Weiler Wolfram Ruf

Sci Immunol 2019 09;4(39)

Center for Thrombosis and Hemostasis, Johannes Gutenberg University Medical Center, Mainz, Germany.

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September 2019

LIM-only protein FHL2 attenuates vascular tissue factor activity, inhibits thrombus formation in mice and genetic variation associates with human venous thrombosis.

Authors:

Chantal Kroone Mariska Vos Timo Rademakers Marijke Kuijpers Mark Hoogenboezem Jaap van Buul Johan W M Heemskerk Wolfram Ruf Astrid van Hylckama Vlieg Henri H Versteeg Marie-José Goumans Carlie J M de Vries Kondababu Kurakula

Haematologica 2020 Jun 29;105(6):1677-1685. Epub 2019 Aug 29.

Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands

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June 2020