Publications by authors named "Wolfgang Wick"

100Publications

Magnetization transfer ratio - a quantitative imaging biomarker for 5q spinal muscular atrophy.

Eur J Neurol 2020 Sep 12. Epub 2020 Sep 12.

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1111/ene.14528DOI Listing
September 2020

Nintedanib and a bi-specific anti-VEGF/Ang2 nanobody selectively prevent brain metastases of lung adenocarcinoma cells.

Clin Exp Metastasis 2020 Sep 12. Epub 2020 Sep 12.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s10585-020-10055-xDOI Listing
September 2020

TERT and DNMT1 expression predict sensitivity to decitabine in gliomas.

Neuro Oncol 2020 Sep 3. Epub 2020 Sep 3.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, INF, Heidelberg, Germany.

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http://dx.doi.org/10.1093/neuonc/noaa207DOI Listing
September 2020

Noninvasive Characterization of Tumor Angiogenesis and Oxygenation in Bevacizumab-treated Recurrent Glioblastoma by Using Dynamic Susceptibility MRI: Secondary Analysis of the European Organization for Research and Treatment of Cancer 26101 Trial.

Radiology 2020 Jul 28:200978. Epub 2020 Jul 28.

From the Department of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany (P.K., G.B., I.P., M.S., M.F., U.N., S.H., M.B.); Center of Functionally Integrative Neuroscience and MINDLab, Aarhus University Hospital, Aarhus, Denmark (M.B.H., L.Ø.); Neurology Clinic, Heidelberg University Hospital, Heidelberg, Germany (M.N., T.K., A.W., W.W.); Department of Neurology, Medical University Innsbruck, Innsbruck, Austria (M.N.); Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (F.I., K.H.M.H.); Clinical Cooperation Unit Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany (T.K., W.W.); Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany (F.S., A.v.D.); Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany (F.S., A.v.D.); Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland (M.W.); Department of Neurology, Medical Faculty Mannheim, MCTN, University of Heidelberg, Mannheim, Germany (M.P.); Pattern Analysis and Learning Group, Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany (K.H.M.H.); Department of Neuroradiology, Aarhus University Hospital, Aarhus, Denmark (L.Ø.); Brain Tumor Center at Erasmus MC Cancer Institute, Rotterdam, the Netherlands (M.J.v.d.B.); and European Organization for Research and Treatment of Cancer (EORTC), Brussels, Belgium (T.G.).

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http://dx.doi.org/10.1148/radiol.2020200978DOI Listing
July 2020

Current usage of tumor treating fields for glioblastoma.

Neurooncol Adv 2020 Jan-Dec;2(1):vdaa069. Epub 2020 Jun 4.

Neurology Clinic, Heidelberg University Medical Center and Clinical Cooperation Unit Neurooncology, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1093/noajnl/vdaa069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345837PMC
June 2020

Highlights of the inaugural ten - the launch of Neuro-Oncology Advances.

Neurooncol Adv 2019 May-Dec;1(1):vdz016. Epub 2019 Aug 28.

Division of Neurosurgery, University Health Network and MacFeeters-Hamilton Neuro-Oncology Program, Princess Margaret Hospital, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1093/noajnl/vdz016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212904PMC
August 2019

Temozolomide and seizure outcomes in a randomized clinical trial of elderly glioblastoma patients.

J Neurooncol 2020 Aug 6;149(1):65-71. Epub 2020 Jul 6.

Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, 610 University Ave, Toronto, ON, M5G2M9, Canada.

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http://dx.doi.org/10.1007/s11060-020-03573-xDOI Listing
August 2020

Synaptic Input to Brain Tumors: Clinical Implications.

Neuro Oncol 2020 Jul 5. Epub 2020 Jul 5.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, INF, Heidelberg.

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http://dx.doi.org/10.1093/neuonc/noaa158DOI Listing
July 2020

Neuronal signatures in cancer.

Int J Cancer 2020 Jun 8. Epub 2020 Jun 8.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.33138DOI Listing
June 2020

Quantitative Dynamic Oxygen 17 MRI at 7.0 T for the Cerebral Oxygen Metabolism in Glioma.

Radiology 2020 04 18;295(1):181-189. Epub 2020 Feb 18.

From the Division of Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany (D.P., M.N.S., S.R., H.P.S.); Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany (A.M.N., R.U., T.P., M.E.L., S.C.N.); Institute of Radiology, University Hospital Erlangen, Erlangen, Germany (A.M.N.); Departments of Radiation Oncology (S.R.), Neurosurgery (M.S., A.U.), Neurology (A.W., W.W.), and Neuroradiology (M.B.), University Hospital Heidelberg, Heidelberg, Germany; and Faculty of Physics and Astronomy and Faculty of Medicine, University of Heidelberg, Heidelberg, Germany (M.E.L.).

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http://dx.doi.org/10.1148/radiol.2020191711DOI Listing
April 2020

Not Yet Another Negative Trial-ReACTing on Recent Glioblastoma Trials.

Clin Cancer Res 2020 Apr 7;26(7):1535-1537. Epub 2020 Feb 7.

University Medical Center & German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-4032DOI Listing
April 2020

Single-nucleus chromatin accessibility reveals intratumoral epigenetic heterogeneity in IDH1 mutant gliomas.

Acta Neuropathol Commun 2019 12 5;7(1):201. Epub 2019 Dec 5.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, INF 460, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s40478-019-0851-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896263PMC
December 2019

cMyc and ERK activity are associated with resistance to ALK inhibitory treatment in glioblastoma.

J Neurooncol 2020 Jan 28;146(1):9-23. Epub 2019 Nov 28.

Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11060-019-03348-zDOI Listing
January 2020

A Phase Ib/II, open-label, multicenter study of INC280 (capmatinib) alone and in combination with buparlisib (BKM120) in adult patients with recurrent glioblastoma.

J Neurooncol 2020 Jan 27;146(1):79-89. Epub 2019 Nov 27.

Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11060-019-03337-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938467PMC
January 2020

Bevacizumab versus alkylating chemotherapy in recurrent glioblastoma.

J Cancer Res Clin Oncol 2020 Mar 21;146(3):659-670. Epub 2019 Nov 21.

Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Frauenklinikstrasse 26, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00432-019-03086-9DOI Listing
March 2020

Emerging intersections between neuroscience and glioma biology.

Nat Neurosci 2019 12 12;22(12):1951-1960. Epub 2019 Nov 12.

Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, INF 400, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41593-019-0540-yDOI Listing
December 2019

Quantitative MR neurography biomarkers in 5q-linked spinal muscular atrophy.

Neurology 2019 08 10;93(7):e653-e664. Epub 2019 Jul 10.

From the Department of Neuroradiology (J.K., T.H., A.P., M.J., S.H., M.B.), Division of Child Neurology and Metabolic Medicine (A.Z., A.S.), Center for Child and Adolescent Medicine, Department of Neurology (G.S., W.W., M.W.), and Department of Neuroradiology (S.H.), Division of Experimental Radiology, Heidelberg University Hospital, Germany; Department of Neurology (J.M.H.), University of Michigan, Ann Arbor; Medical Faculty (M.J.), University of Tübingen; and German Cancer Consortium (DKTK) within the German Cancer Research Center (DKFZ) (W.W.), Heidelberg, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000007945DOI Listing
August 2019

Imaging necrosis during treatment is associated with worse survival in EORTC 26101 study.

Neurology 2019 06 10;92(24):e2754-e2763. Epub 2019 May 10.

From the University Medical Center & German Cancer Research Center (M.N., F.S., I.H., P.K., M.P., M.B., W.W.), Heidelberg, Germany; EORTC Headquarters (T.G., V.G.), Brussels, Belgium; Brain Tumor Center at Erasmus MC Cancer Institute (J.E.C.B., W.T., M.J.v.d.B.), Rotterdam, the Netherlands; Medical Oncology Department (A.A.B.), AUSL-Bologna-IRCCS Scienze Neurologiche, Bologna, Italy; Haaglanden Medical Center (M.J.B.T.), the Hague; Leiden University Medical Center (M.J.B.T.), the Netherlands; Institut Gustave Roussy (J.D.), Villejuif; Sorbonne Université (A.I.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Service de Neurologie 2-Mazarin, Paris; Institut de Cancerologie de l'Ouest (ICO)-Centre Rene Gauducheau (M.C.), Saint-Herblain, France; Leuven Cancer Institute-KU Leuven (P.M.C.), Belgium; Department of Neurology and Brain Tumor Center (M.W.), University Hospital and University of Zurich, Switzerland; Institut Régional du Cancer Montpellier (M.F.); University of Lille (E.L.R.), U-1192, Inserm; CHU Lille (E.L.R.), General and Stereotaxic Neurosurgery Service; Oscar Lambret Center (E.L.R.), Neurology, Lille, France; Department of Neurology (M.P.), Medical Faculty Mannheim, Heidelberg University, Germany; and Department of Neurology (M.N.), Medical University Innsbruck, Austria.

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http://dx.doi.org/10.1212/WNL.0000000000007643DOI Listing
June 2019

Differential Effects of Ang-2/VEGF-A Inhibiting Antibodies in Combination with Radio- or Chemotherapy in Glioma.

Cancers (Basel) 2019 Mar 6;11(3). Epub 2019 Mar 6.

Neurology Clinic and Neurooncology Program at the National Center for Tumor Disease, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.3390/cancers11030314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468722PMC
March 2019

Susceptibility-weighted imaging in malignant melanoma brain metastasis.

J Magn Reson Imaging 2019 10 21;50(4):1251-1259. Epub 2019 Feb 21.

Department of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/jmri.26692DOI Listing
October 2019

Steroid-Responsive Relapsing-Remitting Neutrophilic Encephalitis: A Case Report.

J Neuropathol Exp Neurol 2018 11;77(11):993-996

Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany.

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https://academic.oup.com/jnen/article/77/11/993/5123646
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http://dx.doi.org/10.1093/jnen/nly088DOI Listing
November 2018

First results on the DCVax phase III trial: raising more questions than providing answers.

Neuro Oncol 2018 09;20(10):1283-1284

Erasmus MC Cancer Institute, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1093/neuonc/noy125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120355PMC
September 2018

Perspectives of immunotherapy in isocitrate dehydrogenase-mutant gliomas.

Curr Opin Oncol 2018 11;30(6):368-374

German Cancer Consortium (DKTK) Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ).

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http://dx.doi.org/10.1097/CCO.0000000000000478DOI Listing
November 2018

Treatment of glioblastoma in adults.

Ther Adv Neurol Disord 2018 25;11:1756286418790452. Epub 2018 Jul 25.

Neurology Clinic, University of Heidelberg, Clinical Cooperation Unit (CCU) Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1177/1756286418790452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071154PMC
July 2018

Understanding and Treating Glioblastoma.

Neurol Clin 2018 08;36(3):485-499

Department of Neurology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ncl.2018.04.006DOI Listing
August 2018

Nonmeasurable Speckled Contrast-Enhancing Lesions Appearing During Course of Disease Are Associated With IDH Mutation in High-Grade Astrocytoma Patients.

Int J Radiat Oncol Biol Phys 2018 12 31;102(5):1472-1480. Epub 2018 Jul 31.

Department of Neurology and Neurooncology Program, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2018.07.2004DOI Listing
December 2018

Gd contrast administration is dispensable in patients with MS without new T2 lesions on follow-up MRI.

Neurol Neuroimmunol Neuroinflamm 2018 Sep 16;5(5):e480. Epub 2018 Jul 16.

Department of Neuroradiology (K.K.-J., D.S., M.B., M.O.B.), University Hospital Heidelberg, Im Neuenheimer Feld 400; Neurology Clinic (B.W., R.D., W.W.), University Hospital Heidelberg, Im Neuenheimer Feld 400; Division of Biostatistics (T.H.), German Cancer Research Center, DKFZ, Im Neuenheimer Feld 280; and Clinical Cooperation Unit Neurooncology (W.W.), German Cancer Consortium, German Cancer Research Center, DKFZ, Im Neuenheimer Feld 280, Heidelberg, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053940PMC
September 2018

Associations of anticoagulant use with outcome in newly diagnosed glioblastoma.

Eur J Cancer 2018 09 20;101:95-104. Epub 2018 Jul 20.

Department of Neurology & Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.ejca.2018.06.029DOI Listing
September 2018

New glioblastoma heterogeneity atlas - a shared resource.

Nat Rev Neurol 2018 Aug;14(8):453-454

Neurology Clinic, University of Heidelberg and Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41582-018-0038-3DOI Listing
August 2018

Regimen of procarbazine, lomustine, and vincristine versus temozolomide for gliomas.

Cancer 2018 07 26;124(13):2674-2676. Epub 2018 Apr 26.

Neurology Clinic, University of Heidelberg; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1002/cncr.31371DOI Listing
July 2018

Vaccine Strategies in Gliomas.

Curr Treat Options Neurol 2018 Mar 28;20(5):11. Epub 2018 Mar 28.

Department of Neurology, Heidelberg Medical Center, University of Heidelberg, INF 400, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11940-018-0498-1DOI Listing
March 2018