Wolfgang R Sperr

Wolfgang R Sperr

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Wolfgang R Sperr

Wolfgang R Sperr

Publications by authors named "Wolfgang R Sperr"

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Redistribution, homing and organ-invasion of neoplastic stem cells in myeloid neoplasms.

Semin Cancer Biol 2019 Aug 10. Epub 2019 Aug 10.

Institute of Anatomy and Experimental Morphology, University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.semcancer.2019.07.025DOI Listing
August 2019

Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML.

Int J Mol Sci 2019 Aug 29;20(17). Epub 2019 Aug 29.

Department of Internal Medicine V (Hematology & Oncology), Medical University of Innsbruck, 1090 Innsbruck, Austria.

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http://dx.doi.org/10.3390/ijms20174233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747233PMC
August 2019

Multidisciplinary Challenges in Mastocytosis and How to Address with Personalized Medicine Approaches.

Int J Mol Sci 2019 Jun 18;20(12). Epub 2019 Jun 18.

Division of Allergy and Clinical Immunology, University of Salerno, 84131 Salerno, Italy.

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http://dx.doi.org/10.3390/ijms20122976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627900PMC
June 2019

Additional prognostic impact of the percentage of erythroid cells in the bone marrow of patients with myelodysplastic syndromes.

Leuk Res 2019 02 28;77:8-13. Epub 2018 Dec 28.

University of Rochester Medical Center, Department of Pathology, Hematopathology Unit and James P. Wilmot Cancer Institute, Rochester, NY, USA.

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http://dx.doi.org/10.1016/j.leukres.2018.12.012DOI Listing
February 2019

Major response of PNH to an AML chemotherapy protocol.

Ann Hematol 2018 Aug 22;97(8):1487-1488. Epub 2018 Mar 22.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00277-018-3307-8DOI Listing
August 2018

Phenotyping and Target Expression Profiling of CD34/CD38 and CD34/CD38 Stem- and Progenitor cells in Acute Lymphoblastic Leukemia.

Neoplasia 2018 06 15;20(6):632-642. Epub 2018 May 15.

Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994777PMC
June 2018

Prevalence of comorbidities in periodontitis patients compared with the general Austrian population.

J Periodontol 2018 01;89(1):19-27

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna.

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http://dx.doi.org/10.1902/jop.2017.170333DOI Listing
January 2018

Risk factors and mechanisms contributing to TKI-induced vascular events in patients with CML.

Leuk Res 2017 08 12;59:47-54. Epub 2017 May 12.

Medical Clinic III for Oncology, Haematology, Immunology and Rheumatology, University Hospital Bonn (UKB), Germany.

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http://dx.doi.org/10.1016/j.leukres.2017.05.008DOI Listing
August 2017

Expression of CD25 on leukemic stem cells in BCR-ABL1 CML: Potential diagnostic value and functional implications.

Exp Hematol 2017 07 27;51:17-24. Epub 2017 Apr 27.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X173013
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http://dx.doi.org/10.1016/j.exphem.2017.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044418PMC
July 2017

Evaluation of efficacy of alemtuzumab in 5 patients with aplastic anemia and/or myelodysplastic neoplasm.

Wien Klin Wochenschr 2017 Jun 14;129(11-12):404-410. Epub 2016 Oct 14.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, AKH, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-016-1091-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486731PMC
June 2017

Karyotype plus NPM1 mutation status defines a group of elderly patients with AML (≥60 years) who benefit from intensive post-induction consolidation therapy.

Am J Hematol 2016 12 8;91(12):1239-1245. Epub 2016 Nov 8.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/ajh.24560DOI Listing
December 2016

Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice.

Haematologica 2016 10;101(10):1133-1143

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Austria Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.

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http://dx.doi.org/10.3324/haematol.2016.146563DOI Listing
October 2016

Critically ill patients with cancer: chances and limitations of intensive care medicine-a narrative review.

ESMO Open 2016 13;1(5):e000018. Epub 2016 Sep 13.

Department of Medicine I, Intensive Care Unit 13i2 , Medical University of Vienna , Vienna , Austria.

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http://dx.doi.org/10.1136/esmoopen-2015-000018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070251PMC
September 2016

Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML.

Clin Cancer Res 2016 Apr 25;22(8):2051-61. Epub 2015 Nov 25.

Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria. Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817228PMC
April 2016

A novel pump-driven veno-venous gas exchange system during extracorporeal CO2-removal.

Intensive Care Med 2015 Oct 14;41(10):1773-80. Epub 2015 Jul 14.

Department of Medicine I, Intensive Care Unit 13i2, General Hospital Vienna, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00134-015-3957-0DOI Listing
October 2015

Haematopoietic stem cell transplantation for treatment of primary CNS lymphoma: single-centre experience and literature review.

Eur J Haematol 2015 Jul 23;95(1):75-82. Epub 2015 Mar 23.

Unit for Bone Marrow and Stem Cell Transplantation, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/ejh.12482DOI Listing
July 2015

Long-lasting complete response to imatinib in a patient with systemic mastocytosis exhibiting wild type KIT.

Am J Blood Res 2014 15;4(2):93-100. Epub 2014 Dec 15.

Ludwig Boltzmann Cluster Oncology, Medical University of Vienna Austria ; Department of Dermatology, Medical University of Vienna Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351647PMC
March 2015

Influenza vaccination perception and coverage among patients with malignant disease.

Vaccine 2015 Mar 24;33(14):1682-7. Epub 2015 Feb 24.

Clinical Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of Vienna, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.02.029DOI Listing
March 2015

10th anniversary of the Austrian MDS Platform: aims and ongoing projects.

Wien Klin Wochenschr 2015 Jan 25;127(1-2):12-5. Epub 2014 Nov 25.

Department of Internal Medicine IV, Klinikum Wels-Grieskirchen, Wels, Austria,

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http://dx.doi.org/10.1007/s00508-014-0627-0DOI Listing
January 2015

Chronic mast cell leukemia: a novel leukemia-variant with distinct morphological and clinical features.

Leuk Res 2015 Jan 30;39(1):1-5. Epub 2014 Sep 30.

Institute of Pathology, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1016/j.leukres.2014.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896385PMC
January 2015

Serum-tryptase at diagnosis: a novel biomarker improving prognostication in Ph(+) CML.

Am J Cancer Res 2015 15;5(1):354-62. Epub 2014 Dec 15.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna Vienna, Austria ; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna Vienna, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300686PMC
January 2015

First experience with a new miniaturized pump-driven venovenous extracorporeal CO2 removal system (iLA Activve): a retrospective data analysis.

ASAIO J 2014 May-Jun;60(3):342-7

From the Department of Medicine I, Intensive Care Unit 13i2, Medical University of Vienna, General Hospital of Vienna, Waehringer Guertel, Vienna, Austria.

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http://dx.doi.org/10.1097/MAT.0000000000000073DOI Listing
December 2014

Azacitidine in 302 patients with WHO-defined acute myeloid leukemia: results from the Austrian Azacitidine Registry of the AGMT-Study Group.

Ann Hematol 2014 Nov 21;93(11):1825-38. Epub 2014 Jun 21.

3rd Medical Department with Hematology and Medical Oncology, Hemostaseology, Rheumatology and Infectious Diseases, Laboratory for Immunological and Molecular Cancer Research, Oncologic Center, Paracelsus Medical University Hospital Salzburg, and Center for Clinical Cancer and Immunology Trials at Salzburg Cancer Research Institute, Müllner Hauptstrasse 48, 5020, Salzburg, Austria,

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http://link.springer.com/content/pdf/10.1007/s00277-014-2126
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http://link.springer.com/10.1007/s00277-014-2126-9
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http://dx.doi.org/10.1007/s00277-014-2126-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176957PMC
November 2014

Hematopoietic stem-cell transplantation for advanced systemic mastocytosis.

J Clin Oncol 2014 Oct 25;32(29):3264-74. Epub 2014 Aug 25.

Celalettin Ustun, Ryan Shanley, Gregory Vercellotti, and Daniel Weisdorf, University of Minnesota, Minneapolis; William J. Hogan, Mayo Clinic, Rochester, MN; Andreas Reiter and Sebastian Kreil, Universitätsmedizin Mannheim, Mannheim; Herrad Baurmann, Stiftung Deutsche Klinik für Diagnostik, Wiesbaden; Bernd Gruhn, Jena University Hospital, Jena; Tanja Gromke, University of Essen, Essen; Eva Maria Wagner, Universitätsmedizin Mainz, Mainz; Martin Bornhäuser, Universitätsklinikum Dresden, Dresden; Christoph Schmid, Klinikum Augsburg, Ausburg, Germany; Bart L. Scott and H. Joachim Deeg, University of Washington, Seattle, WA; Ryotaro Nakamura, City of Hope National Medical Center, Duarte; Vinod Pullarkat, University of Southern California, Los Angeles, CA; Gandhi Damaj, Université de Caen, Faculté de Médecine, Caen; Faezeh Legrand, Nice University Hospital, Nice, and Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC); Ibrahim Yakoub-agha, Centre Hospitalier Régionale Universitaire, Lille; Olivier Hermine, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker Enfants-Malades, Université Paris 5 Faculté de Médecine et AP-HP Necker-Enfants Malades, and Centre de Référence des Mastocytoses, Paris, France; Miguel-Angel Perales and Esperanza B. Papadopoulos, Memorial Sloan-Kettering Cancer Center; Tsiporah Shore, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY; Robert Stuart, Medical University of South Carolina, Charleston, SC; Michael Doubek, Masaryk University, Brno, Czech Republic; Jack W. Hsu, University of Florida, Gainesville, FL; Eleni Tholouli, Manchester Royal Infirmary, Manchester, United Kingdom; Lucy A. Godley, University of Chicago, Chicago, IL; Livio Pagano, Università Cattolica del Sacro Cuore, Milan; Maria Teresa Van Lint, Istituto Di Ricovero e Cura a Carattere Scientifico San Martino-IST, Genova, Italy; Andrew Gilman, Levine Children's Hospital, Charlotte, NC; Tor Shwayder, Henry F

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http://dx.doi.org/10.1200/JCO.2014.55.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876356PMC
October 2014

The serum tryptase test: an emerging robust biomarker in clinical hematology.

Expert Rev Hematol 2014 Oct 28;7(5):683-90. Epub 2014 Aug 28.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1586/17474086.2014.955008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603354PMC
October 2014

Clofarabine/cyclophosphamide for debulking before stem cell transplantation.

Eur J Clin Invest 2014 Aug;44(8):775-83

Bone Marrow Transplantation Unit, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria; Intensive Care Unit, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/eci.12294DOI Listing
August 2014

Clustering of comorbidities is related to age and sex and impacts clinical outcome in myelodysplastic syndromes.

J Geriatr Oncol 2014 Jul 11;5(3):299-306. Epub 2014 Mar 11.

Department of Internal Medicine V (Hematology and Oncology), Innsbruck Medical University, Innsbruck, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jgo.2014.02.002DOI Listing
July 2014

Identification of campath-1 (CD52) as novel drug target in neoplastic stem cells in 5q-patients with MDS and AML.

Clin Cancer Res 2014 Jul 5;20(13):3589-602. Epub 2014 May 5.

Authors' Affiliations: Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Austria; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria;

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2811DOI Listing
July 2014

The role of epigenetics in the regulation of apoptosis in myelodysplastic syndromes and acute myeloid leukemia.

Crit Rev Oncol Hematol 2014 Apr 12;90(1):1-16. Epub 2013 Oct 12.

Ludwig Boltzmann Cluster Oncology, Vienna, Austria; Ludwig Boltzmann Institute for Leukemia Research and Hematology, Hanusch Hospital, Vienna, Austria; 3rd Medical Department, Hanusch Hospital, Vienna, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S10408428130021
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http://dx.doi.org/10.1016/j.critrevonc.2013.10.003DOI Listing
April 2014

Azacitidine in CMML: matched-pair analyses of daily-life patients reveal modest effects on clinical course and survival.

Leuk Res 2014 Apr 18;38(4):475-83. Epub 2014 Jan 18.

3rd Medical Department with Hematology and Medical Oncology, Hemostasiology, Rheumatology and Infectiology, Laboratory for Immunological and Molecular Cancer Research, Paracelsus Medical University Hospital Salzburg, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2014.01.006DOI Listing
April 2014

Clinical evidence for a link between microparticle-associated tissue factor activity and overt disseminated intravascular coagulation in patients with acute myelocytic leukemia.

Thromb Res 2014 Mar 30;133(3):303-5. Epub 2013 Dec 30.

Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Austria; Comprehensive Cancer Center Vienna, Medical University of Vienna - Vienna General Hospital, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2013.12.029DOI Listing
March 2014

Evaluation of treatment responses and colony-forming progenitor cells in 50 patients with aplastic anemia after immunosuppressive therapy or hematopoietic stem cell transplantation: a single-center experience.

Wien Klin Wochenschr 2014 Feb 18;126(3-4):119-25. Epub 2014 Jan 18.

Division of Hematology & Hemostaseology, Department of Internal Medicine I, AKH, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria,

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http://link.springer.com/10.1007/s00508-013-0484-2
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http://dx.doi.org/10.1007/s00508-013-0484-2DOI Listing
February 2014

Long-term follow-up after allogeneic stem cell transplantation in patients with myelodysplastic syndromes or secondary acute myeloid leukemia: a single center experience.

Wien Klin Wochenschr 2014 Jan 19;126(1-2):23-9. Epub 2013 Nov 19.

Department of Internal Medicine I, Bone Marrow Transplantation Unit, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-013-0449-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003401PMC
January 2014

Proposed score for survival of patients with myelodysplastic syndromes.

Eur J Clin Invest 2013 Nov 18;43(11):1120-8. Epub 2013 Sep 18.

Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/eci.12149DOI Listing
November 2013

Guidelines and diagnostic algorithm for patients with suspected systemic mastocytosis: a proposal of the Austrian competence network (AUCNM).

Am J Blood Res 2013 5;3(2):174-80. Epub 2013 May 5.

Department of Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna Austria ; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649810PMC
May 2013

Diagnosis, progression patterns and prognostication in mastocytosis.

Expert Rev Hematol 2012 Jun;5(3):261-74

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria.

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http://www.tandfonline.com/doi/full/10.1586/ehm.12.12
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http://dx.doi.org/10.1586/ehm.12.12DOI Listing
June 2012

Severe life-threatening or disabling anaphylaxis in patients with systemic mastocytosis: a single-center experience.

Int Arch Allergy Immunol 2012 25;157(4):399-405. Epub 2011 Nov 25.

Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000329218DOI Listing
May 2012

Idiopathic cytopenia of undetermined significance (ICUS) and idiopathic dysplasia of uncertain significance (IDUS), and their distinction from low risk MDS.

Leuk Res 2012 Jan 13;36(1):1-5. Epub 2011 Sep 13.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.leukres.2011.08.016DOI Listing
January 2012

Successful allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia during respiratory failure and invasive mechanical ventilation.

Wien Klin Wochenschr 2011 Jun 3;123(11-12):354-8. Epub 2011 Jun 3.

Department of Internal Medicine I, Bone Marrow Transplantation Unit, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-011-1590-7DOI Listing
June 2011