Wolfgang Huber

Wolfgang Huber

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Wolfgang Huber

Wolfgang Huber

Publications by authors named "Wolfgang Huber"

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Influence of Sustained Low-Efficiency Dialysis Treatment on Isavuconazole Plasma Levels in Critically Ill Patients.

Antimicrob Agents Chemother 2019 Nov 22;63(11). Epub 2019 Oct 22.

Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität Munich, Munich, Germany.

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http://dx.doi.org/10.1128/AAC.01162-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811396PMC
November 2019

Transpulmonary thermodilution before and during veno-venous extra-corporeal membrane oxygenation ECMO: an observational study on a potential loss of indicator into the extra-corporeal circuit.

J Clin Monit Comput 2019 Nov 5. Epub 2019 Nov 5.

Medizinische Klinik und Poliklinik II, Klinikum rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s10877-019-00398-6DOI Listing
November 2019

Adaptive penalization in high-dimensional regression and classification with external covariates using variational Bayes.

Biostatistics 2019 Oct 9. Epub 2019 Oct 9.

Genome Biology Unit, European Molecular Biology Laboratory, Meyerhofstr. 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1093/biostatistics/kxz034DOI Listing
October 2019

Use of human derived liver cells for the detection of genotoxins in comet assays.

Mutat Res 2019 Sep 10;845:402995. Epub 2018 Dec 10.

Institute of Cancer Research, Department of Internal Medicine 1, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2018.12.003DOI Listing
September 2019

Assessment of a novel, smartglass-based control device for electrically powered wheelchairs.

Disabil Rehabil Assist Technol 2019 Aug 5:1-5. Epub 2019 Aug 5.

a Department of Neurology, Klinikum rechts der Isar, Technische Universität München , München , Germany.

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http://dx.doi.org/10.1080/17483107.2019.1646817DOI Listing
August 2019

Prevalence and outcome of invasive pulmonary aspergillosis in critically ill patients with liver cirrhosis: an observational study.

Sci Rep 2019 Aug 15;9(1):11919. Epub 2019 Aug 15.

Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.

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http://dx.doi.org/10.1038/s41598-019-48183-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695439PMC
August 2019

The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance.

Cell Rep 2019 Jun;27(11):3097-3106.e5

European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.05.039DOI Listing
June 2019

Liver function assessment using indocyanine green plasma disappearance rate in a young male with icteric leptospirosis: a case report.

BMC Infect Dis 2019 May 28;19(1):473. Epub 2019 May 28.

Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technische Universität München, Ismaninger Straße 22, D-81675, Munich, Germany.

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http://dx.doi.org/10.1186/s12879-019-4101-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537418PMC
May 2019

[Treatment of acute necrotizing pancreatitis].

Internist (Berl) 2019 03;60(3):226-234

Medizinische Klinik und Poliklinik II, Universitätsklinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Deutschland.

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http://dx.doi.org/10.1007/s00108-019-0558-yDOI Listing
March 2019

Reporting p Values.

Authors:
Wolfgang Huber

Cell Syst 2019 Mar;8(3):170-171

European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Meyerhofstrasse 1, Heidelberg 69117, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2019.03.001DOI Listing
March 2019

Assessment of Regional Perfusion and Organ Function: Less and Non-invasive Techniques.

Front Med (Lausanne) 2019 22;6:50. Epub 2019 Mar 22.

Medizinische Klinik und Poliklinik II, Klinikum rechts der Isar, Technische Universität München, München, Germany.

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http://dx.doi.org/10.3389/fmed.2019.00050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438879PMC
March 2019

The Small Non-coding Vault RNA1-1 Acts as a Riboregulator of Autophagy.

Cell 2019 Feb 14;176(5):1054-1067.e12. Epub 2019 Feb 14.

European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.01.030DOI Listing
February 2019

Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency.

Cell Syst 2018 11 7;7(5):482-495.e10. Epub 2018 Nov 7.

European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Meyerhofstrasse 1, Heidelberg 69117, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24054712183038
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http://dx.doi.org/10.1016/j.cels.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327227PMC
November 2018

Increased risk of candidemia in patients with necrotising pancreatitis infected with candida species.

Pancreatology 2018 Sep 14;18(6):630-634. Epub 2018 Jul 14.

Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675, München, Germany.

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http://dx.doi.org/10.1016/j.pan.2018.07.005DOI Listing
September 2018

Large-volume paracentesis effects plasma disappearance rate of indo-cyanine green in critically ill patients with decompensated liver cirrhosis and intraabdominal hypertension.

Ann Intensive Care 2018 Jul 6;8(1):78. Epub 2018 Jul 6.

Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1186/s13613-018-0422-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035121PMC
July 2018

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.

Blood 2018 06 13;131(25):2789-2802. Epub 2018 Apr 13.

Molecular Therapy in Haematology and Oncology, Department of Translational Oncology, National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1182/blood-2017-09-806679DOI Listing
June 2018

[Management of Clostridium difficile infections at German intensive care units - results from a survey among intensivists].

Z Gastroenterol 2018 06 11;56(6):551-560. Epub 2018 Jun 11.

Klinik für Gastroenterologie, Stoffwechselerkrankungen und Internistische Intensivmedizin, Uniklinik RWTH Aachen.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-102103
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http://dx.doi.org/10.1055/s-0044-102103DOI Listing
June 2018

Multi-Omics Factor Analysis-a framework for unsupervised integration of multi-omics data sets.

Mol Syst Biol 2018 06 20;14(6):e8124. Epub 2018 Jun 20.

European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, Cambridge, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010767PMC
http://dx.doi.org/10.15252/msb.20178124DOI Listing
June 2018

Proteome-wide identification of ubiquitin interactions using UbIA-MS.

Nat Protoc 2018 03 15;13(3):530-550. Epub 2018 Feb 15.

Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1038/nprot.2017.147DOI Listing
March 2018

Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?

Arch Toxicol 2018 Feb 7;92(2):921-934. Epub 2017 Dec 7.

Department of Internal Medicine I, Institute of Cancer Research, Medical University Vienna, Borschkegasse 8a, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00204-017-2109-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818615PMC
February 2018

Mesenchyme-derived factors enhance preneoplastic growth by non-genotoxic carcinogens in rat liver.

Arch Toxicol 2018 Feb 21;92(2):953-966. Epub 2017 Dec 21.

Department of Medicine I, Comprehensive Cancer Center, Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00204-017-2080-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818586PMC
February 2018

Alternative start and termination sites of transcription drive most transcript isoform differences across human tissues.

Nucleic Acids Res 2018 01;46(2):582-592

European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1093/nar/gkx1165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778607PMC
January 2018

Applicability of stroke volume variation in patients of a general intensive care unit: a longitudinal observational study.

J Clin Monit Comput 2017 Dec 5;31(6):1177-1187. Epub 2016 Nov 5.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s10877-016-9951-4DOI Listing
December 2017

In-parallel connected intermittent hemodialysis through ECMO does not affect hemodynamic parameters derived from transpulmonary thermodilution.

Perfusion 2017 Nov 25;32(8):702-705. Epub 2017 Apr 25.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Germany.

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http://dx.doi.org/10.1177/0267659117707816DOI Listing
November 2017

Upregulation of SPS100 gene expression by an antisense RNA via a switch of mRNA isoforms with different stabilities.

Nucleic Acids Res 2017 Nov;45(19):11144-11158

Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), University of Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/nar/gkx737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737743PMC
November 2017

Questionable Design to Validate the ProAQT/Pulsioflex Device.

Anesth Analg 2017 10;125(4):1417-1420

Medizinische Klinik und Poliklinik II, Klinikum rechts der Isar, Technische Universität München, Munich, Germany,

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http://dx.doi.org/10.1213/ANE.0000000000002333DOI Listing
October 2017

Research Techniques Made Simple: Bioinformatics for Genome-Scale Biology.

J Invest Dermatol 2017 09;137(9):e163-e168

William Harvey Research Institute, Centre for Translational Bioinformatics, Barts and The London School of Medicine and Dentistry, Charterhouse Square, London, UK.

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http://dx.doi.org/10.1016/j.jid.2017.07.095DOI Listing
September 2017

Usefulness of 1,3 Beta-D-Glucan Detection in non-HIV Immunocompromised Mechanical Ventilated Critically Ill Patients with ARDS and Suspected Pneumocystis jirovecii Pneumonia.

Mycopathologia 2017 Aug 4;182(7-8):701-708. Epub 2017 Apr 4.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s11046-017-0132-xDOI Listing
August 2017

Fungal Peritonitis: Underestimated Disease in Critically Ill Patients with Liver Cirrhosis and Spontaneous Peritonitis.

PLoS One 2016 8;11(7):e0158389. Epub 2016 Jul 8.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158389PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938562PMC
July 2017

Consistency of cardiac function index and global ejection fraction with global end-diastolic volume in patients with femoral central venous access for transpulmonary thermodilution: a prospective observational study.

J Clin Monit Comput 2017 Jun 21;31(3):599-605. Epub 2016 Apr 21.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Street 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s10877-016-9880-2DOI Listing
June 2017

[Acute Pancreatitis: What is new?]

Dtsch Med Wochenschr 2017 Apr 7;142(7):525-529. Epub 2017 Apr 7.

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http://dx.doi.org/10.1055/s-0042-100233DOI Listing
April 2017

Advanced Hemodynamic Management in Patients with Septic Shock.

Biomed Res Int 2016 14;2016:8268569. Epub 2016 Sep 14.

Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1155/2016/8268569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039281PMC
March 2017

Functional Outcomes and Quality of Life After Radical Prostatectomy Only Versus a Combination of Prostatectomy with Radiation and Hormonal Therapy.

Eur Urol 2017 03 22;71(3):330-336. Epub 2016 Nov 22.

Martini-Klinik Prostate Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2016.11.015DOI Listing
March 2017

A systematic database-derived approach to improve indexation of transpulmonary thermodilution-derived global end-diastolic volume.

J Clin Monit Comput 2017 Feb 1;31(1):143-151. Epub 2016 Feb 1.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Straße 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s10877-016-9833-9DOI Listing
February 2017

Impact of Therapeutic Plasma Exchange on Hemodynamic Parameters in Medical Intensive Care Unit Patients: An Observational Study.

Artif Organs 2017 Feb 28;41(2):204-209. Epub 2016 Apr 28.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.

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http://dx.doi.org/10.1111/aor.12734DOI Listing
February 2017

Xanthohumol Prevents DNA Damage by Dietary Carcinogens: Results of a Human Intervention Trial.

Cancer Prev Res (Phila) 2017 Feb 6;10(2):153-160. Epub 2016 Dec 6.

Institute of Cancer Research, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1158/1940-6207.CAPR-15-0378DOI Listing
February 2017

First clinical experience in 14 patients treated with ADVOS: a study on feasibility, safety and efficacy of a new type of albumin dialysis.

BMC Gastroenterol 2017 Feb 16;17(1):32. Epub 2017 Feb 16.

Jamaica Hospital Medical Center, 8900 Van Wyck Expy, Jamaica, NY, 11418, USA.

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http://dx.doi.org/10.1186/s12876-017-0569-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312588PMC
February 2017

Usage of 1,3-β-D-Glucan for Early Detection of Invasive Mycoses and Outcome Parameter in Immunocompromised Critically Ill Patients.

Mycopathologia 2016 Dec 12;181(11-12):815-821. Epub 2016 Sep 12.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s11046-016-0061-0DOI Listing
December 2016

Comparison of 1,3-β-d-glucan with galactomannan in serum and bronchoalveolar fluid for the detection of Aspergillus species in immunosuppressed mechanical ventilated critically ill patients.

J Crit Care 2016 12 9;36:259-264. Epub 2016 Jul 9.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität Münche, Munich, Germany.

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http://dx.doi.org/10.1016/j.jcrc.2016.06.026DOI Listing
December 2016

The Shh Topological Domain Facilitates the Action of Remote Enhancers by Reducing the Effects of Genomic Distances.

Dev Cell 2016 12 17;39(5):529-543. Epub 2016 Nov 17.

Developmental Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany; Genome Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2016.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142843PMC
December 2016

Severe hydrocarbon pneumonitis in African refugees after fuel ingestion.

Lancet 2016 11;388(10058):2350-2351

Department of Medicine II, University Hospital Klinikum Rechts der Isar, Munich 81675, Germany.

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http://dx.doi.org/10.1016/S0140-6736(16)32130-4DOI Listing
November 2016

Investigations of the genotoxic properties of two synthetic cathinones (3-MMC, 4-MEC) which are used as psychoactive drugs.

Toxicol Res (Camb) 2016 Sep 22;5(5):1410-1420. Epub 2016 Jul 22.

Institute of Cancer Research , Department of Internal Medicine 1 , Medical University of Vienna , 1090 Vienna , Austria . Email: ; ; Tel: +43-1-40160-57562.

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http://dx.doi.org/10.1039/c6tx00087hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060679PMC
September 2016

Comparison of Serum Galactomannan and 1,3-Beta-D-Glucan Determination for Early Detection of Invasive Pulmonary Aspergillosis in Critically Ill Patients with Hematological Malignancies and Septic Shock.

Mycopathologia 2016 Aug 3;181(7-8):505-11. Epub 2016 May 3.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s11046-016-0011-xDOI Listing
August 2016

Influence of volume administration on Doppler-based renal resistive index, renal hemodynamics and renal function in medical intensive care unit patients with septic-induced acute kidney injury: a pilot study.

Int Urol Nephrol 2016 Aug 18;48(8):1327-1334. Epub 2016 May 18.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der, Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s11255-016-1312-1DOI Listing
August 2016

Data-driven hypothesis weighting increases detection power in genome-scale multiple testing.

Nat Methods 2016 07 30;13(7):577-80. Epub 2016 May 30.

European Molecular Biology Laboratory, Heidelberg, Germany.

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http://dx.doi.org/10.1038/nmeth.3885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930141PMC
July 2016

A clash of cultures in discussions of the P value.

Authors:
Wolfgang Huber

Nat Methods 2016 07;13(8):607

Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

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http://dx.doi.org/10.1038/nmeth.3934DOI Listing
July 2016

Sodium Bicarbonate Prevents Contrast-Induced Nephropathy in Addition to Theophylline: A Randomized Controlled Trial.

Medicine (Baltimore) 2016 May;95(21):e3720

From the II. Medizinische Klinik und Poliklinik (WH, AB, RMS), Klinik für Anaesthesiologie (SS), Klinik und Poliklinik für Vaskuläre und Endovaskuläre Chirurgie (TS) and Krankenhausapotheke (SB), Klinikum rechts der Isar der Technischen Universität München; München; Caritas-Krankenhaus St. Josef, Klinik für Urologie, Regensburg (TH); Kliniken des Landkreises Neumarkt i.d.OPf., Medizinische Klinik I, Neumarkt in der Oberpfalz (CS), Germany; and Universitätsklinik für Innere Medizin I, Landeskrankenhaus, Salzburg (MF), Austria.

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http://dx.doi.org/10.1097/MD.0000000000003720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902357PMC
May 2016

Pseudallescheria boydii with Aspergillus fumigatus and Aspergillus terreus in a Critically Ill Hematopoietic Stem Cell Recipient with ARDS.

Mycopathologia 2016 Apr 11;181(3-4):267-71. Epub 2015 Oct 11.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s11046-015-9952-8DOI Listing
April 2016

Herpes simplex virus in bronchoalveolar lavage fluid of medical intensive care unit patients: Association with lung injury and outcome.

J Crit Care 2016 Apr 8;32:138-44. Epub 2015 Dec 8.

II. Medizinische Klinik und Poliklinik. Klinikum rechts der Isar der Technischen Universität München, 81675 München, Germany.

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http://dx.doi.org/10.1016/j.jcrc.2015.11.019DOI Listing
April 2016

A genetic interaction map of cell cycle regulators.

Mol Biol Cell 2016 Apr 24;27(8):1397-407. Epub 2016 Feb 24.

Division of Signaling and Functional Genomics, German Cancer Research Center, and Department of Cell and Molecular Biology, Heidelberg University, 69120 Heidelberg, Germany

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http://dx.doi.org/10.1091/mbc.E15-07-0467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831891PMC
April 2016

Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause.

Cell 2016 Feb;164(4):668-80

Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; German Cancer Consortium (DKTK), 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.12.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752822PMC
February 2016

TimerQuant: a modelling approach to tandem fluorescent timer design and data interpretation for measuring protein turnover in embryos.

Development 2016 Jan 24;143(1):174-9. Epub 2015 Nov 24.

EMBL Heidelberg, Meyerhofstrasse 1, Heidelberg 69117, Germany.

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http://dx.doi.org/10.1242/dev.125971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725204PMC
January 2016

Influence of echinocandin administration on hemodynamic parameters in medical intensive care unit patients: a single center prospective study.

Infection 2015 Dec 11;43(6):723-7. Epub 2015 Aug 11.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s15010-015-0828-0DOI Listing
December 2015

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins.

Nat Methods 2015 Dec 2;12(12):1129-31. Epub 2015 Nov 2.

Cellzome GmbH, Molecular Discovery Research, GlaxoSmithKline, Heidelberg, Germany.

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http://dx.doi.org/10.1038/nmeth.3652DOI Listing
December 2015

RNA-Seq workflow: gene-level exploratory analysis and differential expression.

F1000Res 2015 14;4:1070. Epub 2015 Oct 14.

European Molecular Biology Laboratory, Heidelberg, Germany.

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http://dx.doi.org/10.12688/f1000research.7035.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670015PMC
December 2015

A chemical-genetic interaction map of small molecules using high-throughput imaging in cancer cells.

Mol Syst Biol 2015 Dec 23;11(12):846. Epub 2015 Dec 23.

Division of Signaling and Functional Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany Department of Cell and Molecular Biology, Heidelberg University, Heidelberg, Germany

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704494PMC
http://dx.doi.org/10.15252/msb.20156400DOI Listing
December 2015

An Optogenetic Method to Modulate Cell Contractility during Tissue Morphogenesis.

Dev Cell 2015 Dec;35(5):646-660

EMBL Heidelberg, Meyerhofstrasse 1, 69117 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2015.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683098PMC
December 2015

SomaticSignatures: inferring mutational signatures from single-nucleotide variants.

Bioinformatics 2015 Nov 10;31(22):3673-5. Epub 2015 Jul 10.

European Molecular Biology Laboratory, Genome Biology Unit, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btv408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817139PMC
November 2015

Outcome prediction, fluid resuscitation, pain management, and antibiotic prophylaxis in severe acute pancreatitis.

Intensive Care Med 2015 Nov 20;41(11):2034-5. Epub 2015 Aug 20.

1. Medizinische Klinik, Klinikum Weiden, Söllnerstr. 16, 92637, Weiden in der Oberpfalz, Germany.

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http://dx.doi.org/10.1007/s00134-015-4022-8DOI Listing
November 2015

Indexation of cardiac output to biometric parameters in critically ill patients: A systematic analysis of a transpulmonary thermodilution-derived database.

J Crit Care 2015 Oct 23;30(5):957-62. Epub 2015 Jun 23.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, 81675 Munich, Germany.

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http://dx.doi.org/10.1016/j.jcrc.2015.06.011DOI Listing
October 2015

Sustained low-efficiency dialysis with regional citrate anticoagulation in medical intensive care unit patients with liver failure: A prospective study.

J Crit Care 2015 Oct 16;30(5):1096-100. Epub 2015 Jun 16.

II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.

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http://dx.doi.org/10.1016/j.jcrc.2015.06.006DOI Listing
October 2015

Mutational landscape and complexity in CLL.

Blood 2015 Oct;126(18):2078-9

EUROPEAN MOLECULAR BIOLOGY LABORATORY.

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http://dx.doi.org/10.1182/blood-2015-09-667584DOI Listing
October 2015

Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells.

Nat Immunol 2015 Sep 3;16(9):933-41. Epub 2015 Aug 3.

1] Department of Genetics, Stanford University, School of Medicine, California, USA. [2] Stanford Genome Technology Center, Stanford University, California, USA. [3] European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany.

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http://dx.doi.org/10.1038/ni.3246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675844PMC
September 2015

Improved binding site assignment by high-resolution mapping of RNA-protein interactions using iCLIP.

Nat Commun 2015 Aug 11;6:7921. Epub 2015 Aug 11.

Department of Pediatric Oncology, Hematology and Immunology, University of Heidelberg, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1038/ncomms8921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918375PMC
August 2015

Comments on Zhang et al.: Effectiveness of treatment based on PiCCO parameters in critically ill patients with septic shock and/or acute respiratory distress syndrome: a randomized controlled trial.

Intensive Care Med 2015 Jul 3;41(7):1389-90. Epub 2015 Jun 3.

II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Ismaningerstraße 22, 81675, Munich, Germany,

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http://dx.doi.org/10.1007/s00134-015-3819-9DOI Listing
July 2015