Publications by authors named "Wolfgang Hartmann"

100Publications

Resistance to avapritinib in PDGFRA-driven GIST is caused by secondary mutations in the PDGFRA kinase domain.

Cancer Discov 2020 Sep 24. Epub 2020 Sep 24.

Department of Medical Oncology, Sarcoma Center, West German Cancer Center, University Duisburg-Essen, Medical School, Essen, Germany; DKTK partner site Essen and German Cancer Consortium (DKTK), Heidelberg, Germany.

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http://dx.doi.org/10.1158/2159-8290.CD-20-0487DOI Listing
September 2020

Analysis of drug sensitivity of human high-grade osteosarcoma in a chick chorioallantoic membrane (CAM) model: a proof of principle study.

BMC Res Notes 2020 Sep 15;13(1):432. Epub 2020 Sep 15.

Department of General and Tumor Orthopedics, University Hospital Muenster, Albert-Schweitzer-Campus 1, Building A1, 48149, Münster, Germany.

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http://dx.doi.org/10.1186/s13104-020-05269-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493185PMC
September 2020

VEGFR2 as a target for CAR T cell therapy of Ewing sarcoma.

Pediatr Blood Cancer 2020 Jul 30:e28313. Epub 2020 Jul 30.

Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.28313DOI Listing
July 2020

Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance.

Acta Neuropathol 2020 05 17;139(5):913-936. Epub 2019 Dec 17.

Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00401-019-02116-7DOI Listing
May 2020

Which Factors Are Associated with Local Control and Survival of Patients with Localized Pelvic Ewing's Sarcoma? A Retrospective Analysis of Data from the Euro-EWING99 Trial.

Clin Orthop Relat Res 2020 02;478(2):290-302

D. Andreou, G. Gosheger, Department of General Orthopedics and Tumor Orthopedics, University Hospital Münster, Westfälische Wilhelms-University, Münster, Germany A. Ranft, U. Dirksen, Pediatrics III, Hematology/Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany B. Timmermann, Clinic for Particle Therapy, West German Proton Therapy Center, University Hospital Essen, Essen, Germany R. Ladenstein, Department of Studies and Statistics on Integrated Research and Projects (S2IRP), Children's Cancer Research Institute, Vienna, Austria W. Hartmann, E. Wardelmann, Gerhard-Domagk-Institute for Pathology, University Hospital Münster, Westfälische Wilhelms-University, Münster, Germany S. Bauer, Department of Medical Oncology, Sarcoma Center, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany D. Baumhoer, Bone Tumor Reference Center, Institute of Pathology, University Hospital Basel, University of Basel, Basel, Switzerland H. van den Berg, Department of Pediatric Oncology, Emma Children's Hospital/Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands P. D. S. Dijkstra, Department of Orthopedic Surgery, Leiden University Medical Center, Leiden, the Netherlands H. R. Dürr, Orthopedic Oncology, Department of Orthopedics, Ludwig-Maximilians University Munich, Campus Grosshadern, Munich, Germany H. Gelderblom, Department of Medical Oncology, Leiden University Medical Center, Leiden, the Netherlands J. Hardes, A Streitbürger, Department of Tumor Orthopedics and Sarcoma Surgery, University Hospital Essen, Essen, Germany L. Hjorth, Department of Paediatrics, Skane University Hospital, Clinical Sciences, Lund University, Lund, Sweden J. Kreyer, Department of Orthopedic and Trauma Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany J. Kruseova, Department of Pediatric Hematology and Oncology, 2nd Medical School, Charles University Prague, Prague, Czech Republic A. Leithner, Department of Orthopedic Surgery, Medical University of Graz, Graz, Austria S. Scobioala, Department of Radiation Oncology, University Hospital Münster, Westfälische Wilhelms-University, Münster, Germany P-U. Tunn, Department of Orthopedic Oncology, HELIOS Klinikum Berlin-Buch, Berlin, Germany R. Windhager, Department of Orthopedics, Medical University of Vienna, Vienna, Austria H. Jürgens, Department of Paediatric Hematology and Oncology, University Hospital Münster, Westfälische Wilhelms-University, Münster, Germany.

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http://dx.doi.org/10.1097/CORR.0000000000000962DOI Listing
February 2020

[Challenges in the diagnosis of cartilage tumors : Morphological spectrum and molecular markers].

Orthopade 2019 Sep;48(9):735-743

Sektion für Translationale Pathologie, Gerhard-Domagk-Institut für Pathologie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, D17, 48149, Münster, Deutschland.

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http://dx.doi.org/10.1007/s00132-019-03787-6DOI Listing
September 2019

EZH2 Inhibition in Ewing Sarcoma Upregulates G Expression for Targeting with Gene-Modified T Cells.

Mol Ther 2019 05 23;27(5):933-946. Epub 2019 Feb 23.

Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, 48149 Münster, Germany; Cells-in-Motion Cluster of Excellence (EXC 1003 - CiM), University of Münster, 48149 Münster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2019.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520468PMC
May 2019

Are formalin-fixed and paraffin-embedded tissues fit for proteomic analysis?

J Mass Spectrom 2020 Aug 10;55(8):e4347. Epub 2019 Apr 10.

Core Unit Proteomics, Interdisciplinary Center for Clinical Research, Medical Faculty, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1002/jms.4347DOI Listing
August 2020

SS18-SSX-Dependent YAP/TAZ Signaling in Synovial Sarcoma.

Clin Cancer Res 2019 06 27;25(12):3718-3731. Epub 2019 Feb 27.

Division of Translational Pathology, Gerhard-Domagk-Institute of Pathology, Münster University Hospital, Münster, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-3553DOI Listing
June 2019

High-Dose Chemotherapy and Blood Autologous Stem-Cell Rescue Compared With Standard Chemotherapy in Localized High-Risk Ewing Sarcoma: Results of Euro-E.W.I.N.G.99 and Ewing-2008.

J Clin Oncol 2018 Sep 6:JCO2018782516. Epub 2018 Sep 6.

Jeremy Whelan, University College Hospital; Ian Judson, Institute of Cancer Research, London; Bernadette Brennan, Royal Manchester Children's Hospital, Manchester; Bruce Morland, Birmingham Children's Hospital; Keith Wheatley, University of Birmingham, Birmingham; Ian Lewis, Leeds Community Healthcare National Health Service Trust, Leeds; Alan Craft, Newcastle University, Newcastle upon Tyne, United Kingdom; Marie-Cecile Le Deley and Cyril Lervat, Centre Oscar Lambret, Lille; Gwénaël Le Teuff, Nathalie Gaspar, and Odile Oberlin, Institut Gustave Roussy, Villejuif; Jean-Yves Blay, Centre Léon Bérard; Perrine Marec-Berard, Institute of Pediatric Onco-Haematology, Lyon; Marie-Pierre Castex, Centre Hospitalier Universitaire de Toulouse, Toulouse; Jean-Claude Gentet, Centre Hospitalier Universitaire La Timone, Marseille; Marta Jimenez, Unicancer; Valerie Laurence and Jean Michon, Institut Curie, Paris; France; Uta Dirksen, Sebastian Bauer, Andreas Ranft, University Hospital Essen, Essen; Susanne Amler, Institut für Biometrie und Klinische Forschung; Wolfgang Hartmann and Heribert Juergens, Universitätsklinikum, Münster, Münster; Stefan Bielack, Klinikum Stuttgart, Stuttgart; Stefan Burdach, Comprehensive Cancer Center, München; Dagmar Dilloo, University-Clinic Bonn, Bonn; Angelika Eggert, Charité University; Peter Reichardt, HELIOS Klinikum Berlin-Buch, Berlin; Wolf-Achim Hassenpflug, University Medical Center Hamburg-Eppendorf, Hamburg; Thomas Klingebiel, Childrens University Hospital, Frankfurt; Udo Kontny, University Medical Center Aachen, Aachen; Michael Paulussen, Children's and Adolescents' Hospital, Datteln; Germany; Douglas S. Hawkins, Seattle Children's Hospital, Seattle, WA; Hans Gelderblom, Leiden University Medical Center, Leiden; Hendrik van den Berg, University of Amsterdam, Amsterdam, the Netherlands; Lars Hjorth, Skane University Hospital, Lund, Sweden; Jarmila Kruseova, Faculty Hospital Motol Prague, Prague, Czech Republic; Ruth Ladenstein, St Anna Children's Hospital and Children's Cancer Research Institute, Vienna, Austria; Sandrine Marreaud, European Organisation for Research and Treatment of Cancer, Brussels, Belgium.

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http://ascopubs.org/doi/10.1200/JCO.2018.78.2516
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http://dx.doi.org/10.1200/JCO.2018.78.2516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209090PMC
September 2018

Y-ibritumomab-tiuxetan as a therapeutic alternative for follicular lymphoma (FL): A single-center experience.

Eur J Haematol 2018 Oct 3;101(4):514-521. Epub 2018 Sep 3.

Department of Medicine A, Hematology, Oncology and Pulmonary Medicine, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1111/ejh.13138DOI Listing
October 2018

Stromal collagen type VI associates with features of malignancy and predicts poor prognosis in salivary gland cancer.

Cell Oncol (Dordr) 2018 Oct 15;41(5):517-525. Epub 2018 Jun 15.

Gerhard-Domagk-Institute of Pathology, University Hospital Münster, Albert Schweitzer Campus 1, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s13402-018-0389-1DOI Listing
October 2018

Are EWSR1-NFATc2-positive sarcomas really Ewing sarcomas?

Mod Pathol 2018 06 12;31(6):997-999. Epub 2018 Jun 12.

Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41379-018-0009-7DOI Listing
June 2018

AAA+ ATPases Reptin and Pontin as potential diagnostic and prognostic biomarkers in salivary gland cancer - a short report.

Cell Oncol (Dordr) 2018 Aug 5;41(4):455-462. Epub 2018 Jun 5.

Gerhard-Domagk-Institute for Pathology, University Hospital of Münster, Albert Schweitzer Campus 1 D17, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s13402-018-0382-8DOI Listing
August 2018

SWOG study shows significant long-term overall survival for advanced gastrointestinal stromal tumor patients with imatinib treatment.

Transl Gastroenterol Hepatol 2018 8;3:10. Epub 2018 Feb 8.

Gerhard-Domagk-Institute of Pathology, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.21037/tgh.2018.01.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847908PMC
February 2018

Programmed cell death ligand 1 (PD-L1) expression is not a predominant feature in Ewing sarcomas.

Pediatr Blood Cancer 2018 Jan 4;65(1). Epub 2017 Sep 4.

Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.26719DOI Listing
January 2018

Successful second allogeneic stem cell transplantation in a patient with T-lymphoblastic leukemia (T-ALL) relapsed as myeloid sarcoma.

Ann Hematol 2017 Jul 27;96(7):1201-1203. Epub 2017 Apr 27.

Department of Medicine A, Hematology and Oncology, University of Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.

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http://link.springer.com/10.1007/s00277-017-3000-3
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http://dx.doi.org/10.1007/s00277-017-3000-3DOI Listing
July 2017

Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G.

Oncoimmunology 2017 28;6(1):e1250050. Epub 2016 Oct 28.

Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany; Cells-in-Motion Cluster of Excellence (EXC 1003 - CiM), University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1080/2162402X.2016.1250050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283645PMC
October 2016

MDM2 gene amplification in esophageal carcinoma.

Oncol Rep 2016 Apr 20;35(4):2223-7. Epub 2016 Jan 20.

Institute for Pathology, University Hospital of Cologne, Cologne 50924, Germany.

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http://dx.doi.org/10.3892/or.2016.4578DOI Listing
April 2016

Regulators of Actin Dynamics in Gastrointestinal Tract Tumors.

Gastroenterol Res Pract 2015 4;2015:930157. Epub 2015 Aug 4.

Gerhard Domagk Institute of Pathology, University Hospital Münster, 48149 Münster, Germany.

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http://dx.doi.org/10.1155/2015/930157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539459PMC
September 2015

Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma.

Clin Cancer Res 2015 Nov 15;21(21):4935-46. Epub 2015 Jul 15.

Department of Medicine A, Hematology, and Oncology, University Hospital of Muenster, Muenster, Germany. Department of Medicine IV, Hematology and Oncology, State Center for Cell and Gene Therapy, University Hospital Halle, Halle (Saale), Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2744DOI Listing
November 2015

Classification of KIT/PDGFRA wild-type gastrointestinal stromal tumors: implications for therapy.

Expert Rev Anticancer Ther 2015 Jun 1;15(6):623-8. Epub 2015 Apr 1.

Gerhard-Domagk-Institute of Pathology, University Hospital Münster, Building D17, Albert-Schweitzer-Campus 1, Münster 48149, Germany.

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http://dx.doi.org/10.1586/14737140.2015.1032941DOI Listing
June 2015

Detection of SMARCB1 loss in ascites cells in the diagnosis of an abdominal rhabdoid tumor.

Pediatr Blood Cancer 2015 May 7;62(5):897-900. Epub 2015 Feb 7.

Pediatric Hematology and Oncology, University Childrens Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1002/pbc.25412DOI Listing
May 2015

TGF-β1-dependent induction and nuclear translocation of FHL2 promotes keratin expression in pilomatricoma.

Virchows Arch 2015 Feb 5;466(2):199-208. Epub 2014 Dec 5.

Institute of Pathology, University of Cologne Medical School, Kerpener Str. 62, 50924, Cologne, Germany.

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http://dx.doi.org/10.1007/s00428-014-1692-5DOI Listing
February 2015

MiR-34a deficiency accelerates medulloblastoma formation in vivo.

Int J Cancer 2015 May 25;136(10):2293-303. Epub 2014 Nov 25.

Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Hufelandstr. 55 45147, Essen, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), D-69120, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29294DOI Listing
May 2015

Gastrointestinal stromal tumors with KIT exon 9 mutations: Update on genotype-phenotype correlation and validation of a high-resolution melting assay for mutational testing.

Am J Surg Pathol 2013 Nov;37(11):1648-59

*Institute of Pathology, University of Cologne Medical Center, Cologne †Gerhard-Domagk-Institute of Pathology, University of Münster Medical Center, Münster ‡Department of General and Abdominal Surgery, University of Mainz Medical Center, Mainz §Division of Surgical Oncology and Thoracic Surgery, University of Mannheim Medical Center, Mannheim ∥Department of Hematology, Oncology and Palliative Care, Sarcoma Center Berlin-Brandenburg, HELIOS Klinikum Bad Saarow, Bad Saarow, Germany.

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http://dx.doi.org/10.1097/PAS.0b013e3182986b88DOI Listing
November 2013

MicroRNA profiling of primary high-grade soft tissue sarcomas.

Genes Chromosomes Cancer 2012 Nov 18;51(11):982-96. Epub 2012 Jul 18.

Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1002/gcc.21980DOI Listing
November 2012

Activating PDGFRA mutations in inflammatory fibroid polyps occur in exons 12, 14 and 18 and are associated with tumour localization.

Histopathology 2012 Jul 6;61(1):59-68. Epub 2012 Mar 6.

Institute of Pathology, University of Cologne Medical Center, Cologne, Germany Institute of Pathology, University of Bonn Medical Center, Bonn, Germany.

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http://dx.doi.org/10.1111/j.1365-2559.2012.04203.xDOI Listing
July 2012