Wolfgang Enard

Wolfgang Enard

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Wolfgang Enard

Wolfgang Enard

Publications by authors named "Wolfgang Enard"

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Epithelial Planar Bipolarity Emerges from Notch-Mediated Asymmetric Inhibition of Emx2.

Curr Biol 2020 Mar 27;30(6):1142-1151.e6. Epub 2020 Feb 27.

Research Unit of Sensory Biology & Organogenesis, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2020.01.027DOI Listing
March 2020

A systematic evaluation of single cell RNA-seq analysis pipelines.

Nat Commun 2019 10 11;10(1):4667. Epub 2019 Oct 11.

Anthropology and Human Genomics, Department of Biology II, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1038/s41467-019-12266-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789098PMC
October 2019

Studying Cancer Heterogeneity by Single-Cell RNA Sequencing.

Methods Mol Biol 2019 ;1956:305-319

Anthropology & Human Genomics, Department of Biology II, Ludwig-Maximilians-University, Martinsried, Germany.

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http://dx.doi.org/10.1007/978-1-4939-9151-8_14DOI Listing
July 2019

Chivosazole A Modulates Protein-Protein Interactions of Actin.

J Nat Prod 2019 07 1;82(7):1961-1970. Epub 2019 Jul 1.

Department of Pharmacy , Ludwig-Maximilians-University , 81377 Munich , Germany.

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http://dx.doi.org/10.1021/acs.jnatprod.9b00335DOI Listing
July 2019

Neandertal Introgression Sheds Light on Modern Human Endocranial Globularity.

Curr Biol 2019 01 13;29(1):120-127.e5. Epub 2018 Dec 13.

Language and Genetics Department, Max Planck Institute for Psycholinguistics, P.O. Box 310, 6500 AH, Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2018.10.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380688PMC
January 2019

Transcriptional effects of actin-binding compounds: the cytoplasm sets the tone.

Cell Mol Life Sci 2018 Dec 11;75(24):4539-4555. Epub 2018 Sep 11.

Department of Pharmacy, Center for Drug Research, Ludwig-Maximilians-University Munich, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s00018-018-2919-4DOI Listing
December 2018

Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata).

Sci Rep 2018 08 15;8(1):12187. Epub 2018 Aug 15.

Molecular Biology Section, Department of Cellular and Molecular Biology, Primate Research Institute, Kyoto University, Inuyama, Aichi, 484-8506, Japan.

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http://dx.doi.org/10.1038/s41598-018-30734-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093926PMC
August 2018

Quantitative single-cell transcriptomics.

Brief Funct Genomics 2018 07;17(4):220-232

Anthropology and Human Genomics, Department of Biology II, Ludwig-Maximilians University, Großhaderner Str. 2, Martinsried, Germany.

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http://dx.doi.org/10.1093/bfgp/ely009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063296PMC
July 2018

Sensitive and powerful single-cell RNA sequencing using mcSCRB-seq.

Nat Commun 2018 07 26;9(1):2937. Epub 2018 Jul 26.

Anthropology & Human Genomics, Department of Biology II, Ludwig-Maximilians-University, Großhaderner Straße 2, 82152, Martinsried, Germany.

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http://www.nature.com/articles/s41467-018-05347-6
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http://dx.doi.org/10.1038/s41467-018-05347-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062574PMC
July 2018

zUMIs - A fast and flexible pipeline to process RNA sequencing data with UMIs.

Gigascience 2018 06;7(6)

Anthropology and Human Genomics, Department of Biology II, Ludwig-Maximilians University, Grosshaderner Str. 2, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1093/gigascience/giy059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007394PMC
June 2018

Micropatterning as a tool to identify regulatory triggers and kinetics of actin-mediated endothelial mechanosensing.

J Cell Sci 2018 05 29;131(10). Epub 2018 May 29.

Ludwig-Maximilians-University Munich, Department of Pharmacy, Center for Drug Research, 81377 Munich, Germany

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http://dx.doi.org/10.1242/jcs.212886DOI Listing
May 2018

powsimR: power analysis for bulk and single cell RNA-seq experiments.

Bioinformatics 2017 Nov;33(21):3486-3488

Anthropology & Human Genomics, Department of Biology II, Ludwig-Maximilians University, 82152 Munich, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btx435DOI Listing
November 2017

Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes.

Glia 2017 03 29;65(3):474-488. Epub 2016 Dec 29.

Department of Drug Design and Pharmacology, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, 2100, Denmark.

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http://dx.doi.org/10.1002/glia.23105DOI Listing
March 2017

Comparative Analysis of Single-Cell RNA Sequencing Methods.

Mol Cell 2017 Feb;65(4):631-643.e4

Anthropology & Human Genomics, Department of Biology II, Ludwig-Maximilians University, Großhaderner Straße 2, 82152 Martinsried, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.01.023DOI Listing
February 2017

Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia.

Cancer Cell 2016 Dec 1;30(6):849-862. Epub 2016 Dec 1.

Department of Gene Vectors, Helmholtz Zentrum München, German Center for Environmental Health (HMGU), 81377 Munich, Germany; German Consortium for Translational Cancer Research (DKTK), Partnering Site, Munich, 81377 Munich, Germany; Department of Pediatrics, Dr. von Hauner Children's Hospital, Ludwig Maximilians University München, 80337 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156313PMC
December 2016

The Molecular Basis of Human Brain Evolution.

Authors:
Wolfgang Enard

Curr Biol 2016 10;26(20):R1109-R1117

Department of Biology II, Ludwig Maximilian University Munich, Grosshaderner Str. 2, D-82152 Martinsried, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2016.09.030DOI Listing
October 2016

The impact of amplification on differential expression analyses by RNA-seq.

Sci Rep 2016 05 9;6:25533. Epub 2016 May 9.

Anthropology &Human Genomics, Department of Biology II, Ludwig-Maximilians University, Großhaderner Str. 2, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1038/srep25533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860583PMC
May 2016

Human evolution: enhancing the brain.

Authors:
Wolfgang Enard

Curr Biol 2015 May;25(10):R421-3

Department of Biology II, Ludwig Maximilian University Munich, Martinsried, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.03.031DOI Listing
May 2015

Mouse models of human evolution.

Authors:
Wolfgang Enard

Curr Opin Genet Dev 2014 Dec 16;29:75-80. Epub 2014 Sep 16.

Department of Biology II, Ludwig Maximilian University Munich, Martinsried, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2014.08.008DOI Listing
December 2014

Comparative genomics of brain size evolution.

Authors:
Wolfgang Enard

Front Hum Neurosci 2014 21;8:345. Epub 2014 May 21.

Department of Biology II, Ludwig Maximilian University Munich Munich, Germany.

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http://dx.doi.org/10.3389/fnhum.2014.00345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033227PMC
June 2014

Primate iPS cells as tools for evolutionary analyses.

Stem Cell Res 2014 May 8;12(3):622-9. Epub 2014 Feb 8.

Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103 Leipzig, Germany; Department Biology II, Ludwig Maximilian University Munich, D-82152 Martinsried, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2014.02.001DOI Listing
May 2014

Convergent repression of Foxp2 3'UTR by miR-9 and miR-132 in embryonic mouse neocortex: implications for radial migration of neurons.

Development 2012 Sep 8;139(18):3332-42. Epub 2012 Aug 8.

Department of Neuroscience and Brain Technologies, Fondazione Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy.

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http://dx.doi.org/10.1242/dev.078063DOI Listing
September 2012

Functional primate genomics--leveraging the medical potential.

Authors:
Wolfgang Enard

J Mol Med (Berl) 2012 May 4;90(5):471-80. Epub 2012 May 4.

Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1007/s00109-012-0901-4DOI Listing
May 2012

FOXP2 and the role of cortico-basal ganglia circuits in speech and language evolution.

Authors:
Wolfgang Enard

Curr Opin Neurobiol 2011 Jun 16;21(3):415-24. Epub 2011 May 16.

Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103 Leipzig, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S095943881100066
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http://dx.doi.org/10.1016/j.conb.2011.04.008DOI Listing
June 2011

Structural and functional evolution of the trace amine-associated receptors TAAR3, TAAR4 and TAAR5 in primates.

PLoS One 2010 Jun 15;5(6):e11133. Epub 2010 Jun 15.

Institute of Biochemistry, Molecular Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011133PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886124PMC
June 2010

Comment on papers by Evans et al. and Mekel-Bobrov et al. on Evidence for Positive Selection of MCPH1 and ASPM.

Science 2007 Aug;317(5841):1036; author reply 1036

MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK.

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http://dx.doi.org/10.1126/science.1141705DOI Listing
August 2007

FUNC: a package for detecting significant associations between gene sets and ontological annotations.

BMC Bioinformatics 2007 Feb 6;8:41. Epub 2007 Feb 6.

Max-Planck-Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1186/1471-2105-8-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800870PMC
February 2007

Evolution of primate gene expression.

Nat Rev Genet 2006 Sep;7(9):693-702

Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1038/nrg1940DOI Listing
September 2006

Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells.

Proc Natl Acad Sci U S A 2006 Jul 23;103(27):10438-10443. Epub 2006 Jun 23.

*Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D-01307 Dresden, Germany; and

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http://dx.doi.org/10.1073/pnas.0604066103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502476PMC
July 2006

Functional analysis of human and chimpanzee promoters.

Genome Biol 2005 1;6(7):R57. Epub 2005 Jul 1.

Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1186/gb-2005-6-7-r57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175988PMC
June 2006

Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees.

Science 2005 Sep 1;309(5742):1850-4. Epub 2005 Sep 1.

Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103 Leipzig, Germany.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1108296
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http://dx.doi.org/10.1126/science.1108296DOI Listing
September 2005

Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings.

Am J Hum Genet 2005 May 31;76(5):717-28. Epub 2005 Mar 31.

Department of Medical Genetics, Cambridge Institute for Medical Research, Cambridge, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297076072
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http://dx.doi.org/10.1086/429930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199363PMC
May 2005

Comparative primate genomics.

Annu Rev Genomics Hum Genet 2004 ;5:351-78

Max-Planck Institute for Evolutionary Anthropology, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1146/annurev.genom.5.061903.180040DOI Listing
November 2004

A neutral model of transcriptome evolution.

PLoS Biol 2004 May 11;2(5):E132. Epub 2004 May 11.

Max-Planck-Institute for Evolutionary Anthropology, Leipzig, Germany.

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http://dx.doi.org/10.1371/journal.pbio.0020132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC406393PMC
May 2004

Selection on human genes as revealed by comparisons to chimpanzee cDNA.

Genome Res 2003 May;13(5):831-7

Max Planck Institute for Evolutionary Anthropology, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1101/gr.944903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC430916PMC
May 2003

Molecular evolution of FOXP2, a gene involved in speech and language.

Nature 2002 Aug 14;418(6900):869-72. Epub 2002 Aug 14.

Max Planck Institute for Evolutionary Anthropology, Inselstrasse 22, D-04103 Leipzig, Germany.

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http://www.nature.com/articles/nature01025
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http://dx.doi.org/10.1038/nature01025DOI Listing
August 2002