Wolf-Karsten Hofmann

Wolf-Karsten Hofmann

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Wolf-Karsten Hofmann

Wolf-Karsten Hofmann

Publications by authors named "Wolf-Karsten Hofmann"

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DNA Damage and DNA Damage Response in Chronic Myeloid Leukemia.

Int J Mol Sci 2020 Feb 11;21(4). Epub 2020 Feb 11.

Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.

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http://dx.doi.org/10.3390/ijms21041177DOI Listing
February 2020

An increased bone mineral density is an adverse prognostic factor in patients with systemic mastocytosis.

J Cancer Res Clin Oncol 2020 Jan 24. Epub 2020 Jan 24.

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1007/s00432-019-03119-3DOI Listing
January 2020

Magnetic resonance imaging reveals distinct bone marrow patterns in indolent and advanced systemic mastocytosis.

Ann Hematol 2019 Dec 5;98(12):2693-2701. Epub 2019 Nov 5.

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1007/s00277-019-03826-4DOI Listing
December 2019

Cancer patients and music: (prospective) results from a survey to evaluate potential complementary treatment approaches.

J Cancer Res Clin Oncol 2019 Aug 5;145(8):2141-2148. Epub 2019 Jul 5.

Department of Medicine III, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

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http://dx.doi.org/10.1007/s00432-019-02959-3DOI Listing
August 2019

Tolerability and efficacy of deferasirox in patients with transfusional iron overload: results from a German 2-year non-interventional study.

J Cancer Res Clin Oncol 2018 Aug 14;144(8):1531-1538. Epub 2018 May 14.

Department of Hematology and Oncology, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

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http://dx.doi.org/10.1007/s00432-018-2665-xDOI Listing
August 2018

Safety and efficacy of the CD95-ligand inhibitor asunercept in transfusion-dependent patients with low and intermediate risk MDS.

Leuk Res 2018 05 10;68:62-69. Epub 2018 Mar 10.

Department of Hematology and Oncology, University Hospital Mannheim, Mannheim, Germany; Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2018.03.007DOI Listing
May 2018

Enhanced labile plasma iron and outcome in acute myeloid leukaemia and myelodysplastic syndrome after allogeneic haemopoietic cell transplantation (ALLIVE): a prospective, multicentre, observational trial.

Lancet Haematol 2018 May 5;5(5):e201-e210. Epub 2018 Apr 5.

Medizinische Fakultät Carl-Gustav-Carus der Technischen Universität, Medizinische Klinik und Poliklinik I, University Hospital Carl-Gustav-Carus, Dresden, Germany; National Center for Tumor Diseases (NCT)-Partner Site Dresden, Dresden, Germany; German Cancer Consortium (DKTK), Partner Site Dresden, Germany.

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http://dx.doi.org/10.1016/S2352-3026(18)30036-XDOI Listing
May 2018

[Acute Promyelocytic Leukemia - A Rare, Life-Threatening Disease with High Healing Chance].

Dtsch Med Wochenschr 2018 02 6;143(3):152-156. Epub 2018 Feb 6.

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http://dx.doi.org/10.1055/s-0043-122862DOI Listing
February 2018

The evolving landscape of new diagnostic tests for invasive aspergillosis in hematology patients: strengths and weaknesses.

Curr Opin Infect Dis 2017 Dec;30(6):539-544

aDepartment of Internal Medicine - Hematology and Oncology, Mannheim University Hospital, Heidelberg University, Heidelberg bSecond Department of Internal Medicine, Brandenburg University Hospital, Brandenburg, Germany cDivision of Infectious Diseases, Department of Medicine, University of California -San Diego, San Diego, California, USA dSection of Infectious Diseases and Tropical Medicine, Department of Internal Medicine eDivision of Pulmonology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1097/QCO.0000000000000408DOI Listing
December 2017

Immunofluorescence Microscopy of γH2AX and 53BP1 for Analyzing the Formation and Repair of DNA Double-strand Breaks.

J Vis Exp 2017 11 3(129). Epub 2017 Nov 3.

Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University.

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http://dx.doi.org/10.3791/56617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755291PMC
November 2017

[Not Available].

Dtsch Med Wochenschr 2017 Oct 10;142(20):1502-1507. Epub 2017 Oct 10.

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http://dx.doi.org/10.1055/s-0042-116216DOI Listing
October 2017

Infectious complications in patients with myelodysplastic syndromes: A review of the literature with emphasis on patients treated with 5-azacitidine.

Eur J Haematol 2017 Aug 20;99(2):112-118. Epub 2017 Apr 20.

Department of Hematology and Oncology, University Hospital Mannheim, Mannheim, Germany.

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http://doi.wiley.com/10.1111/ejh.12883
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http://dx.doi.org/10.1111/ejh.12883DOI Listing
August 2017

Increase of DNA damage and alteration of the DNA damage response in myelodysplastic syndromes and acute myeloid leukemias.

Leuk Res 2017 06 21;57:112-118. Epub 2017 Mar 21.

Department of Hematology and Oncology, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1016/j.leukres.2017.03.011DOI Listing
June 2017

Evaluating the use of PCR for diagnosing invasive aspergillosis.

Expert Rev Mol Diagn 2017 06 10;17(6):603-610. Epub 2017 May 10.

a Department of Internal Medicine -Hematology and Oncology , Mannheim University Hospital, University of Heidelberg , Mannheim , Germany.

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http://dx.doi.org/10.1080/14737159.2017.1325735DOI Listing
June 2017

Concomitant MDS with isolated 5q deletion and MGUS: case report and review of molecular aspects.

Eur J Haematol 2017 Mar 27;98(3):302-310. Epub 2016 Dec 27.

Medical faculty Mannheim of the University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1111/ejh.12827DOI Listing
March 2017

[Antifungal medication: new substances, new experiences].

Dtsch Med Wochenschr 2016 Nov 30;141(24):1752-1756. Epub 2016 Nov 30.

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http://dx.doi.org/10.1055/s-0042-117166DOI Listing
November 2016

Measurement of separase proteolytic activity in single living cells by a fluorogenic flow cytometry assay.

PLoS One 2015 12;10(8):e0133769. Epub 2015 Aug 12.

III. Medizinische Universitätsklinik, (Hämatologie und Onkologie), Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133769PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534294PMC
May 2016

Impact of centralized evaluation of bone marrow histology in systemic mastocytosis.

Eur J Clin Invest 2016 May 21;46(5):392-7. Epub 2016 Mar 21.

Department of Hematology and Oncology, University Medical Centre Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1111/eci.12607DOI Listing
May 2016

Risk of Infectious Complications in Hemato-Oncological Patients Treated with Kinase Inhibitors.

Biomark Insights 2015 21;10(Suppl 3):55-68. Epub 2016 Apr 21.

Department of Hematology and Oncology, Mannheim University Hospital, University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.4137/BMI.S22430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841329PMC
April 2016

Diagnostic challenges in the work up of hypereosinophilia: pitfalls in bone marrow core biopsy interpretation.

Ann Hematol 2016 Mar 22;95(4):557-62. Epub 2016 Jan 22.

III. Medizinische Klinik, Hämatologie und Onkologie, Universitätsmedizin Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1007/s00277-016-2598-xDOI Listing
March 2016

c-MYB is a transcriptional regulator of ESPL1/Separase in BCR-ABL-positive chronic myeloid leukemia.

Biomark Res 2016 2;4. Epub 2016 Mar 2.

III. Medizinische Klinik (Hämatologie und Onkologie), Wissenschaftliches Labor, Medizinische Fakultät Mannheim der Universität Heidelberg, Pettenkofer Str. 22, 68169 Mannheim, Germany.

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http://dx.doi.org/10.1186/s40364-016-0059-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774018PMC
March 2016

Does physical activity improve quality of life in cancer patients undergoing chemotherapy?

Oncol Res Treat 2015 4;38(5):230-6. Epub 2015 May 4.

III. Medizinische Klinik, Universitätsmedizin Mannheim, Universität Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1159/000381734DOI Listing
February 2016

Direct comparison of galactomannan performance in concurrent serum and bronchoalveolar lavage samples in immunocompromised patients at risk for invasive pulmonary aspergillosis.

Mycoses 2016 Feb 2;59(2):80-5. Epub 2015 Dec 2.

Department of Hematology and Oncology, Mannheim University Hospital, University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1111/myc.12434DOI Listing
February 2016

Biomarker-based diagnostic work-up of invasive pulmonary aspergillosis in immunocompromised paediatric patients--is Aspergillus PCR appropriate?

Mycoses 2016 Feb 14;59(2):67-74. Epub 2015 Dec 14.

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1111/myc.12443DOI Listing
February 2016

Takotsubo cardiomyopathy after systemic consolidation therapy with high-dose intravenous cytarabine in a patient with acute myeloid leukemia.

Oncol Res Treat 2014 11;37(9):487-90. Epub 2014 Jul 11.

First Department of Medicine, Faculty of Medicine Mannheim, University Medical Center Mannheim (UMM), University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1159/000365536DOI Listing
May 2015

Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance.

Exp Hematol 2015 Jan 29;43(1):32-43.e1-35. Epub 2014 Oct 29.

Division of Hematology and Oncology, Cedars Sinai Medical Center, University of California, Los Angeles, School of Medicine, Los Angeles, CA, United States; National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1016/j.exphem.2014.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894481PMC
January 2015

Assessment of acute intestinal graft versus host disease by abdominal magnetic resonance imaging at 3 Tesla.

Eur Radiol 2014 Aug 27;24(8):1835-44. Epub 2014 May 27.

Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany,

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http://dx.doi.org/10.1007/s00330-014-3224-8DOI Listing
August 2014

The risk of infections in hematologic patients treated with rituximab is not influenced by cumulative rituximab dosage - a single center experience.

BMC Infect Dis 2014 Jul 3;14:364. Epub 2014 Jul 3.

Department of Hematology and Oncology, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, Mannheim, Germany.

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http://dx.doi.org/10.1186/1471-2334-14-364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227097PMC
July 2014

Coinfection of Pneumocystis jirovecii and invasive pulmonary aspergillosis in an immunocompromised patient: a diagnostic challenge.

Onkologie 2013 16;36(10):582-4. Epub 2013 Sep 16.

Department of Hematology and Oncology, Mannheim University Hospital, University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1159/000355168DOI Listing
June 2014

Mast cell sarcoma mimicking metastatic colon carcinoma.

Ann Hematol 2014 Jun 19;93(6):1067-9. Epub 2013 Oct 19.

III. Medizinische Klinik, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

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http://dx.doi.org/10.1007/s00277-013-1931-xDOI Listing
June 2014

Characteristics, treatment and prognostic factors of patients with gynaecological malignancies treated in a palliative care unit at a university hospital.

Onkologie 2013 18;36(11):642-8. Epub 2013 Oct 18.

III. Medizinische Klinik, Hämatologie und Onkologie, Universitätsmedizin Mannheim, Universität Heidelberg, Germany.

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http://dx.doi.org/10.1159/000355642DOI Listing
June 2014

Cancer patients and advance directives: a survey of patients in a hematology and oncology outpatient clinic.

Onkologie 2013 8;36(7-8):398-402. Epub 2013 Jul 8.

III. Medizinische Klinik, Universitätsmedizin Mannheim, Universität Heidelberg, Germany.

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http://dx.doi.org/10.1159/000353604DOI Listing
March 2014

Centrosome aberrations in bone marrow cells from patients with myelodysplastic syndromes correlate with chromosomal instability.

Ann Hematol 2013 Oct 5;92(10):1325-33. Epub 2013 May 5.

III. Medizinische Klinik, Hämatologie und Onkologie, Medizinische Fakultät Mannheim der Universität Heidelberg, Universitätsmedizin Mannheim, Pettenkoferstrasse 22, 68169 Mannheim, Germany.

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http://dx.doi.org/10.1007/s00277-013-1772-7DOI Listing
October 2013

Management of elderly patients with acute promyelocytic leukemia: progress and problems.

Ann Hematol 2013 Sep 22;92(9):1181-8. Epub 2013 May 22.

Department of Hematology and Oncology, University Hospital Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1007/s00277-013-1788-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734597PMC
September 2013

Treatment of acute promyelocytic leukemia with arsenic trioxide: clinical results and open questions.

Expert Rev Anticancer Ther 2013 Sep;13(9):1035-43

Department of Hematology and Oncology, University Hospital Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1586/14737140.2013.833681DOI Listing
September 2013

Effects of imatinib mesylate in patients with polycythemia vera: results of a phase II study.

Ann Hematol 2013 Jul 24;92(7):907-15. Epub 2013 Mar 24.

III. Medizinische Klinik, Hämatologie und Onkologie, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

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http://link.springer.com/content/pdf/10.1007/s00277-013-1725
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http://link.springer.com/10.1007/s00277-013-1725-1
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http://dx.doi.org/10.1007/s00277-013-1725-1DOI Listing
July 2013

Acute leukemias of ambiguous lineage in adults: molecular and clinical characterization.

Ann Hematol 2013 Jun 15;92(6):747-58. Epub 2013 Feb 15.

Department of Hematology, Oncology and Tumor Immunology, Charité University Hospital Berlin, Hindenburgdamm 30, 12203, Campus Benjamin Franklin, Berlin, Germany.

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http://dx.doi.org/10.1007/s00277-013-1694-4DOI Listing
June 2013

Globular intracytoplasmic inclusions in a patient with chronic lymphocytic leukaemia.

Br J Haematol 2013 May 25;161(3):302. Epub 2013 Feb 25.

III. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1111/bjh.12273DOI Listing
May 2013