Winnie S Liang

Winnie S Liang

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Winnie S Liang

Winnie S Liang

Publications by authors named "Winnie S Liang"

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63Publications

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A virome-wide clonal integration analysis platform for discovering cancer viral etiology.

Genome Res 2019 05 14;29(5):819-830. Epub 2019 Mar 14.

Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont 05405, USA.

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http://dx.doi.org/10.1101/gr.242529.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499315PMC
May 2019

Circular RNA expression and function in the brain.

Noncoding RNA Res 2019 Mar 5;4(1):23-29. Epub 2019 Jan 5.

Translational Genomics Research Institute, Phoenix, AZ, USA.

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http://dx.doi.org/10.1016/j.ncrna.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404376PMC
March 2019

Identification of therapeutic targets in chordoma through comprehensive genomic and transcriptomic analyses.

Cold Spring Harb Mol Case Stud 2018 12 17;4(6). Epub 2018 Dec 17.

Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona 85013, USA.

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http://molecularcasestudies.cshlp.org/lookup/doi/10.1101/mcs
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http://dx.doi.org/10.1101/mcs.a003418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318766PMC
December 2018

Amyloid-β Increases Tau by Mediating Sirtuin 3 in Alzheimer's Disease.

Mol Neurobiol 2018 Nov 24;55(11):8592-8601. Epub 2018 Mar 24.

Barrow Neurological Institute, St. Joseph Hospital and Medical Center, Phoenix, AZ, USA.

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http://dx.doi.org/10.1007/s12035-018-0977-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677544PMC
November 2018

Whole Genome Library Construction for Next Generation Sequencing.

Methods Mol Biol 2018 ;1706:151-161

Translational Genomics Research Institute (TGen), 445 N. Fifth Street, Phoenix, AZ, 85004, USA.

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http://dx.doi.org/10.1007/978-1-4939-7471-9_8DOI Listing
October 2018

Whole Exome Library Construction for Next Generation Sequencing.

Methods Mol Biol 2018 ;1706:163-174

Translational Genomics Research Institute (TGen), 445 N. Fifth Street, Phoenix, AZ, 85004, USA.

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http://dx.doi.org/10.1007/978-1-4939-7471-9_9DOI Listing
October 2018

Sirtuin 3 attenuates amyloid-β induced neuronal hypometabolism.

Aging (Albany NY) 2018 10;10(10):2874-2883

Department of Neurology, Barrow Neurological Institute, St. Joseph Hospital and Medical Center, Dignity Health Organization, Phoenix, AZ 85013, USA.

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http://www.aging-us.com/article/101592/text
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http://dx.doi.org/10.18632/aging.101592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224231PMC
October 2018

Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.

Neuron 2018 07 21;99(1):64-82.e7. Epub 2018 Jun 21.

Departments of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute of Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ 85287-5001, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551233PMC
July 2018

Oligomeric amyloid β preferentially targets neuronal and not glial mitochondrial-encoded mRNAs.

Alzheimers Dement 2018 06 23;14(6):775-786. Epub 2018 Jan 23.

ASU-Banner Biodesign Neurodegenerative Disease Research Center, Biodesign Institute, and School of Life Sciences, Arizona State University, Tempe, AZ.

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http://dx.doi.org/10.1016/j.jalz.2017.12.005DOI Listing
June 2018

Laser-captured microglia in the Alzheimer's and Parkinson's brain reveal unique regional expression profiles and suggest a potential role for hepatitis B in the Alzheimer's brain.

Neurobiol Aging 2018 03 1;63:12-21. Epub 2017 Nov 1.

Biodesign, ASU-Banner Biodesign Neurodegenerative Disease Research Center, School of Life Sciences, Arizona State University, Tempe, AZ, USA; Banner Sun Health Research Institute, Sun City, AZ, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686891PMC
March 2018

ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity.

PLoS One 2017 12;12(7):e0177814. Epub 2017 Jul 12.

Biodesign, ASU-Banner Biodesign Neurodegenerative Disease Research Center, and School of Life Sciences, Arizona State University, Tempe, AZ, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177814PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507536PMC
September 2017

Necroptosis activation in Alzheimer's disease.

Nat Neurosci 2017 Sep 24;20(9):1236-1246. Epub 2017 Jul 24.

Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, Arizona, USA.

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http://dx.doi.org/10.1038/nn.4608DOI Listing
September 2017

Next-generation profiling to identify the molecular etiology of Parkinson dementia.

Neurol Genet 2016 Jun 24;2(3):e75. Epub 2016 May 24.

Neurogenomics Division (A.H.-S., J.J.C., M.D.B., L.C., W.S.L., M.H., T.L.D.), Collaborative Sequencing Center (L.C., W.S.L.), Translational Genomics Research Institute, Phoenix; Division of Neurology (C.A., E.D.-D.), Mayo Clinic, Scottsdale; Banner Sun Health Research Institute (T.G.B.), Sun City, AZ.

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http://dx.doi.org/10.1212/NXG.0000000000000075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881621PMC
June 2016

Whole-genome bisulfite sequencing of cell-free DNA identifies signature associated with metastatic breast cancer.

Clin Epigenetics 2015 16;7:100. Epub 2015 Sep 16.

Integrated Cancer Genomics Division, Translational Genomics Research Institute, 445 N Fifth Street, Phoenix, AZ USA.

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http://www.clinicalepigeneticsjournal.com/content/7/1/100
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http://dx.doi.org/10.1186/s13148-015-0135-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573288PMC
September 2015

Evidence Suggesting That Discontinuous Dosing of ALK Kinase Inhibitors May Prolong Control of ALK+ Tumors.

Cancer Res 2015 Jul 27;75(14):2916-27. Epub 2015 May 27.

BIO5 Institute, University of Arizona, Tucson, Arizona. Department of Medicine, University of Arizona, Tucson, Arizona. Department of Pharmacology and Toxicology, University of Arizona, Tucson, Arizona.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506255PMC
July 2015

Alzheimer's disease is associated with altered expression of genes involved in immune response and mitochondrial processes in astrocytes.

Neurobiol Aging 2015 Feb 2;36(2):583-91. Epub 2014 Oct 2.

Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA; Arizona Alzheimer's Consortium, Phoenix, AZ, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.09.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315763PMC
February 2015

Detection of an atypical teratoid rhabdoid brain tumor gene deletion in circulating blood using next-generation sequencing.

J Child Neurol 2014 Sep 17;29(9):NP81-5. Epub 2013 Oct 17.

Phoenix Children's Hospital, Phoenix, Arizona, USA TGen (Translational Genomics Institute), Phoenix, Arizona, USA

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http://dx.doi.org/10.1177/0883073813503904DOI Listing
September 2014

Open-access synthetic spike-in mRNA-seq data for cancer gene fusions.

BMC Genomics 2014 Sep 30;15:824. Epub 2014 Sep 30.

Translational Genomics Research Institute (TGen), 445 N 5th Street, SUITE 600, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1186/1471-2164-15-824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190330PMC
September 2014

A pilot study using next-generation sequencing in advanced cancers: feasibility and challenges.

PLoS One 2013 30;8(10):e76438. Epub 2013 Oct 30.

Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare (VGPCC), Scottsdale, Arizona, United States of America ; The Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076438PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813699PMC
August 2014

Simultaneous characterization of somatic events and HPV-18 integration in a metastatic cervical carcinoma patient using DNA and RNA sequencing.

Int J Gynecol Cancer 2014 Feb;24(2):329-38

*Translational Genomics Research Institute; †Comprehensive Cancer Care, St Joseph's Hospital and Medical Center, Phoenix; ‡Mayo Clinic, Scottsdale; §Department of Obstetrics and Gynecology, St Joseph's Hospital and Medical Center, and ∥Division of Gynecologic Oncology, Creighton University School of Medicine, St Joseph's Hospital and Medical Center, University of Arizona Cancer Center, Phoenix, AZ.

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http://dx.doi.org/10.1097/IGC.0000000000000049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921261PMC
February 2014

Long insert whole genome sequencing for copy number variant and translocation detection.

Nucleic Acids Res 2014 Jan 25;42(2):e8. Epub 2013 Sep 25.

Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA, Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA and Cancer Treatment Centers of America, Medical Oncology, Goodyear, AZ, 85338, USA.

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http://dx.doi.org/10.1093/nar/gkt865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902897PMC
January 2014

Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways.

J Comp Neurol 2009 Feb;512(4):556-72

Department of Psychiatry and the Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, San Francisco, California 94158-2324, USA.

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http://dx.doi.org/10.1002/cne.21854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761428PMC
February 2009

A novel role for cyclooxygenase-2 in regulating vascular channel formation by human breast cancer cells.

Breast Cancer Res 2006 ;8(6):R69

Department of Biochemistry and Molecular Biology, Mayo Clinic, 13400 E, Shea Blvd, Scottsdale, Arizona 85259, USA.

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http://dx.doi.org/10.1186/bcr1626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797025PMC
February 2007