Publications by authors named "Winand N M Dinjens"

153 Publications

RET FISH analysis is a sensitive but highly unspecific screening method for RET fusions in lung cancer.

Authors:
Teodora Radonic W R R Geurts-Giele Kris G Samsom Guido M J M Roemen Jan H von der Thüsen Erik B J M Thunnissen Isabelle C Meijssen Hein F B M Sleddens Winand N M Dinjens Mirjam C Boelens Karin Weijers Ernst Jan M Speel Stephen P Finn Cathal O'Brien Tom van Wezel Danielle Cohen Kim Monkhorst Paul Roepman H J Dubbink

J Thorac Oncol 2021 Feb 12. Epub 2021 Feb 12.

Department of Pathology, Erasmus MC Cancer Institute, Dr. Molewaterplein 40, 3015 GD Rotterdam, the Netherlands.

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February 2021

Gynecological Surveillance and Surgery Outcomes in Dutch Lynch Syndrome Carriers.

Authors:
Ellis L Eikenboom Helena C van Doorn Winand N M Dinjens Hendrikus J Dubbink Willemina R R Geurts-Giele Manon C W Spaander Carli M J Tops Anja Wagner Anne Goverde

Cancers (Basel) 2021 Jan 26;13(3). Epub 2021 Jan 26.

Department of Clinical Genetics, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.

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January 2021

Sarcoma classification by DNA methylation profiling.

Authors:
Christian Koelsche Daniel Schrimpf Damian Stichel Martin Sill Felix Sahm David E Reuss Mirjam Blattner Barbara Worst Christoph E Heilig Katja Beck Peter Horak Simon Kreutzfeldt Elke Paff Sebastian Stark Pascal Johann Florian Selt Jonas Ecker Dominik Sturm Kristian W Pajtler Annekathrin Reinhardt Annika K Wefers Philipp Sievers Azadeh Ebrahimi Abigail Suwala Francisco Fernández-Klett Belén Casalini Andrey Korshunov Volker Hovestadt Felix K F Kommoss Mark Kriegsmann Matthias Schick Melanie Bewerunge-Hudler Till Milde Olaf Witt Andreas E Kulozik Marcel Kool Laura Romero-Pérez Thomas G P Grünewald Thomas Kirchner Wolfgang Wick Michael Platten Andreas Unterberg Matthias Uhl Amir Abdollahi Jürgen Debus Burkhard Lehner Christian Thomas Martin Hasselblatt Werner Paulus Christian Hartmann Ori Staszewski Marco Prinz Jürgen Hench Stephan Frank Yvonne M H Versleijen-Jonkers Marije E Weidema Thomas Mentzel Klaus Griewank Enrique de Álava Juan Díaz Martín Miguel A Idoate Gastearena Kenneth Tou-En Chang Sharon Yin Yee Low Adrian Cuevas-Bourdier Michel Mittelbronn Martin Mynarek Stefan Rutkowski Ulrich Schüller Viktor F Mautner Jens Schittenhelm Jonathan Serrano Matija Snuderl Reinhard Büttner Thomas Klingebiel Rolf Buslei Manfred Gessler Pieter Wesseling Winand N M Dinjens Sebastian Brandner Zane Jaunmuktane Iben Lyskjær Peter Schirmacher Albrecht Stenzinger Benedikt Brors Hanno Glimm Christoph Heining Oscar M Tirado Miguel Sáinz-Jaspeado Jaume Mora Javier Alonso Xavier Garcia Del Muro Sebastian Moran Manel Esteller Jamal K Benhamida Marc Ladanyi Eva Wardelmann Cristina Antonescu Adrienne Flanagan Uta Dirksen Peter Hohenberger Daniel Baumhoer Wolfgang Hartmann Christian Vokuhl Uta Flucke Iver Petersen Gunhild Mechtersheimer David Capper David T W Jones Stefan Fröhling Stefan M Pfister Andreas von Deimling

Nat Commun 2021 01 21;12(1):498. Epub 2021 Jan 21.

Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.

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January 2021

Plasma Predictive Features in Treating EGFR-Mutated Non-Small Cell Lung Cancer.

Authors:
Christi M J Steendam G D Marijn Veerman Melinda A Pruis Peggy Atmodimedjo Marthe S Paats Cor van der Leest Jan H von der Thüsen David C Y Yick Esther Oomen-de Hoop Stijn L W Koolen Winand N M Dinjens Ron H N van Schaik Ron H J Mathijssen Joachim G J V Aerts Hendrikus Jan Dubbink Anne-Marie C Dingemans

Cancers (Basel) 2020 Oct 29;12(11). Epub 2020 Oct 29.

Department of Pulmonology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.

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October 2020

Multicenter Comparison of Molecular Tumor Boards in The Netherlands: Definition, Composition, Methods, and Targeted Therapy Recommendations.

Authors:
Bart Koopman Harry J M Groen Marjolijn J L Ligtenberg Katrien Grünberg Kim Monkhorst Adrianus J de Langen Mirjam C Boelens Marthe S Paats Jan H von der Thüsen Winand N M Dinjens Nienke Solleveld Tom van Wezel Hans Gelderblom Lizza E Hendriks Ernst-Jan M Speel Tom E Theunissen Leonie I Kroeze Niven Mehra Berber Piet Anthonie J van der Wekken Arja Ter Elst Wim Timens Stefan M Willems Ruud W J Meijers Wendy W J de Leng Anne S R van Lindert Teodora Radonic Sayed M S Hashemi Daniëlle A M Heideman Ed Schuuring Léon C van Kempen

Oncologist 2020 Oct 28. Epub 2020 Oct 28.

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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October 2020

Comparison of variant allele frequency and number of mutant molecules as units of measurement for circulating tumor DNA.

Authors:
Manouk K Bos Kazem Nasserinejad Maurice P H M Jansen Lindsay Angus Peggy N Atmodimedjo Evert de Jonge Winand N M Dinjens Ron H N van Schaik Marzia Del Re Hendrikus J Dubbink Stefan Sleijfer John W M Martens

Mol Oncol 2021 Jan 31;15(1):57-66. Epub 2020 Oct 31.

Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands.

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January 2021

The clonal relation of primary upper urinary tract urothelial carcinoma and paired urothelial carcinoma of the bladder.

Authors:
Thomas van Doeveren Jose A Nakauma-Gonzalez Andrew S Mason Geert J L H van Leenders Tahlita C M Zuiverloon Ellen C Zwarthoff Isabelle C Meijssen Angelique C van der Made Antoine G van der Heijden Kees Hendricksen Bas W G van Rhijn Charlotte S Voskuilen Job van Riet Winand N M Dinjens Hendrikus J Dubbink Harmen J G van de Werken Joost L Boormans

Int J Cancer 2021 Feb 13;148(4):981-987. Epub 2020 Oct 13.

Department of Urology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands.

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February 2021

"The leading role of pathology in assessing the somatic molecular alterations of cancer: Position Paper of the European Society of Pathology": letter to the Editor.

Authors:
Winand N M Dinjens Marjolijn J L Ligtenberg Tom van Wezel Ed Schuuring Hendrikus Jan Dubbink

Virchows Arch 2020 Aug 6. Epub 2020 Aug 6.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

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August 2020

Anisometric Cell and Dysplastic Lipomas in a Retinoblastoma Patient.

Authors:
Michael A den Bakker Dorine T den Toom Tim H C Damen Hein F B M Sleddens Isabella C Meijssen Stijn Deloose Mike Kliffen Winand N M Dinjens

Int J Surg Pathol 2020 Oct 4;28(7):793-798. Epub 2020 May 4.

Erasmus MC Cancer Institute, Rotterdam, Netherlands.

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October 2020

Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.

Authors:
Matthew Clarke Alan Mackay Britta Ismer Jessica C Pickles Ruth G Tatevossian Scott Newman Tejus A Bale Iris Stoler Elisa Izquierdo Sara Temelso Diana M Carvalho Valeria Molinari Anna Burford Louise Howell Alex Virasami Amy R Fairchild Aimee Avery Jane Chalker Mark Kristiansen Kelly Haupfear James D Dalton Wilda Orisme Ji Wen Michael Hubank Kathreena M Kurian Catherine Rowe Mellissa Maybury Stephen Crosier Jeffrey Knipstein Ulrich Schüller Uwe Kordes David E Kram Matija Snuderl Leslie Bridges Andrew J Martin Lawrence J Doey Safa Al-Sarraj Christopher Chandler Bassel Zebian Claire Cairns Rachael Natrajan Jessica K R Boult Simon P Robinson Martin Sill Ira J Dunkel Stephen W Gilheeney Marc K Rosenblum Debbie Hughes Paula Z Proszek Tobey J Macdonald Matthias Preusser Christine Haberler Irene Slavc Roger Packer Ho-Keung Ng Shani Caspi Mara Popović Barbara Faganel Kotnik Matthew D Wood Lissa Baird Monika Ashok Davare David A Solomon Thale Kristin Olsen Petter Brandal Michael Farrell Jane B Cryan Michael Capra Michael Karremann Jens Schittenhelm Martin U Schuhmann Martin Ebinger Winand N M Dinjens Kornelius Kerl Simone Hettmer Torsten Pietsch Felipe Andreiuolo Pablo Hernáiz Driever Andrey Korshunov Lotte Hiddingh Barbara C Worst Dominik Sturm Marc Zuckermann Olaf Witt Tabitha Bloom Clare Mitchell Evelina Miele Giovanna Stefania Colafati Francesca Diomedi-Camassei Simon Bailey Andrew S Moore Timothy E G Hassall Stephen P Lowis Maria Tsoli Mark J Cowley David S Ziegler Matthias A Karajannis Kristian Aquilina Darren R Hargrave Fernando Carceller Lynley V Marshall Andreas von Deimling Christof M Kramm Stefan M Pfister Felix Sahm Suzanne J Baker Angela Mastronuzzi Andrea Carai Maria Vinci David Capper Sergey Popov David W Ellison Thomas S Jacques David T W Jones Chris Jones

Cancer Discov 2020 Jul 1;10(7):942-963. Epub 2020 Apr 1.

Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.

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July 2020

Loss of Y-Chromosome during Male Breast Carcinogenesis.

Authors:
Marie Colombe Agahozo Mieke A M Timmermans Hein F B M Sleddens Renée Foekens Anita M A C Trapman-Jansen Carolien P Schröder Elise van Leeuwen-Stok John W M Martens Winand N M Dinjens Carolien H M van Deurzen

Cancers (Basel) 2020 Mar 9;12(3). Epub 2020 Mar 9.

Department of Pathology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.

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March 2020

Mutations in Serum Circulating Cell-Free Tumor DNA As Longitudinal Biomarker for High-Grade Serous Ovarian Cancer.

Authors:
Silvia R Vitale Floris H Groenendijk Ronald van Marion Corine M Beaufort Jean C Helmijr Hendrikus Jan Dubbink Winand N M Dinjens Patricia C Ewing-Graham Ramon Smolders Helena C van Doorn Ingrid A Boere Els M J J Berns Jozien Helleman Maurice P H M Jansen

Biomolecules 2020 03 7;10(3). Epub 2020 Mar 7.

Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands.

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March 2020

Explaining sudden infant death with cardiac arrhythmias: Complete exon sequencing of nine cardiac arrhythmia genes in Dutch SIDS cases highlights new and known DNA variants.

Authors:
Germaine Liebrechts-Akkerman Fan Liu Ronald van Marion Winand N M Dinjens Manfred Kayser

Forensic Sci Int Genet 2020 05 27;46:102266. Epub 2020 Feb 27.

Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands. Electronic address:

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May 2020

Impact of panel design and cut-off on tumour mutational burden assessment in metastatic solid tumour samples.

Authors:
Joanne M Mankor Marthe S Paats Floris H Groenendijk Paul Roepman Winand N M Dinjens Hendrikus J Dubbink Stefan Sleijfer Edwin Cuppen Martijn P J K Lolkema

Br J Cancer 2020 03 25;122(7):953-956. Epub 2020 Feb 25.

Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus MC, Rotterdam, The Netherlands.

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March 2020

Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification.

Authors:
Mieke R Van Bockstal Marie Colombe Agahozo Ronald van Marion Peggy N Atmodimedjo Hein F B M Sleddens Winand N M Dinjens Lindy L Visser Esther H Lips Jelle Wesseling Carolien H M van Deurzen

Mol Oncol 2020 04 5;14(4):671-685. Epub 2020 Mar 5.

Department of Pathology, Erasmus MC Cancer Institute Rotterdam, The Netherlands.

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April 2020

Implementation of Novel Molecular Biomarkers for Non-small Cell Lung Cancer in the Netherlands: How to Deal With Increasing Complexity.

Authors:
Daan van den Broek T Jeroen N Hiltermann Bonne Biesma Winand N M Dinjens Nils A 't Hart John W J Hinrichs Mathie P G Leers Kim Monkhorst Matthijs van Oosterhout Volkher Scharnhorst Ed Schuuring Ernst-Jan M Speel Michel M van den Heuvel Ron H N van Schaik Jan von der Thüsen Stefan M Willems Leonie de Visser Marjolijn J L Ligtenberg

Front Oncol 2019 22;9:1521. Epub 2020 Jan 22.

Department of Human Genetics, Radboud University Medical Center, Nijmegen, Netherlands.

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January 2020

Development of esophageal squamous cell cancer in patients with FAMMM syndrome: Two clinical reports.

Authors:
Berend J van der Wilk Bo J Noordman Peggy N Atmodimedjo Winand N M Dinjens Robert J F Laheij Anja Wagner Bas P L Wijnhoven J Jan B van Lanschot

Eur J Med Genet 2020 Mar 7;63(3):103840. Epub 2020 Jan 7.

Department of Surgery, Erasmus MC - University Medical Center, Rotterdam, the Netherlands.

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March 2020

Yield of Lynch Syndrome Surveillance for Patients With Pathogenic Variants in DNA Mismatch Repair Genes.

Authors:
Anne Goverde Ellis L Eikenboom Ellemieke L Viskil Marco J Bruno Michael Doukas Winand N M Dinjens Erik Jan Dubbink Ans M W van den Ouweland Robert M W Hofstra Anja Wagner Manon C W Spaander

Clin Gastroenterol Hepatol 2020 May 27;18(5):1112-1120.e1. Epub 2019 Aug 27.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands. Electronic address:

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May 2020

Phenotype or Genotype: Decision-Making Dilemmas in Hepatocellular Adenoma.

Authors:
Anne J Klompenhouwer Maarten G J Thomeer Winand N M Dinjens Robert A de Man Jan N M Ijzermans Michail Doukas

Hepatology 2019 11 12;70(5):1866-1868. Epub 2019 Aug 12.

Department of Pathology, Erasmus University Medical Center, Rotterdam, the Netherlands.

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November 2019

Molecular Alterations in Dog Pheochromocytomas and Paragangliomas.

Authors:
Esther Korpershoek Daphne A E R Dieduksman Guy C M Grinwis Michael J Day Claudia E Reusch Monika Hilbe Federico Fracassi Niels M G Krol André G Uitterlinden Annelies de Klein Bert Eussen Hans Stoop Ronald R de Krijger Sara Galac Winand N M Dinjens

Cancers (Basel) 2019 Apr 30;11(5). Epub 2019 Apr 30.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.

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April 2019

Correction: Functional Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects.

Authors:
Titia G Meijer Nicole S Verkaik Anieta M Sieuwerts Job van Riet Kishan A T Naipal Carolien H M van Deurzen Michael A den Bakker Hein F B M Sleddens Hendrikus-Jan Dubbink T Dorine den Toom Winand N M Dinjens Esther Lips Petra M Nederlof Marcel Smid Harmen J G van de Werken Roland Kanaar John W M Martens Agnes Jager Dik C van Gent

Clin Cancer Res 2019 May;25(9):2935

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May 2019

Estrogen receptor variants in ER-positive basal-type breast cancers responding to therapy like ER-negative breast cancers.

Authors:
Floris H Groenendijk Tina Treece Erin Yoder Paul Baron Peter Beitsch William Audeh Winand N M Dinjens Rene Bernards Pat Whitworth

NPJ Breast Cancer 2019 18;5:15. Epub 2019 Apr 18.

Nashville Breast Center, Nashville, TN USA.

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April 2019

Recommendations for the clinical interpretation and reporting of copy number gains using gene panel NGS analysis in routine diagnostics.

Authors:
Astrid Eijkelenboom Bastiaan B J Tops Anke van den Berg Adrianus J C van den Brule Winand N M Dinjens Hendrikus J Dubbink Arja Ter Elst Willemina R R Geurts-Giele Patricia J T A Groenen Floris H Groenendijk Daniëlle A M Heideman Manon M H Huibers Cornelis J J Huijsmans Judith W M Jeuken Léon C van Kempen Esther Korpershoek Leonie I Kroeze Wendy W J de Leng Carel J M van Noesel Ernst-Jan M Speel Maartje J Vogel Tom van Wezel Petra M Nederlof Ed Schuuring Marjolijn J L Ligtenberg

Virchows Arch 2019 Jun 19;474(6):673-680. Epub 2019 Mar 19.

Department of Pathology, Radboud university medical center, Nijmegen, The Netherlands.

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June 2019

PIK3CA mutations in ductal carcinoma in situ and adjacent invasive breast cancer.

Authors:
Marie Colombe Agahozo Anieta M Sieuwerts S Charlane Doebar Esther I Verhoef Corine M Beaufort Kirsten Ruigrok-Ritstier Vanja de Weerd Hein F B M Sleddens Winand N M Dinjens John W M Martens Carolien H M van Deurzen

Endocr Relat Cancer 2019 05;26(5):471-482

Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

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May 2019

Genome-wide methylation profiling and copy number analysis in atypical fibroxanthomas and pleomorphic dermal sarcomas indicate a similar molecular phenotype.

Authors:
Christian Koelsche Damian Stichel Klaus G Griewank Daniel Schrimpf David E Reuss Melanie Bewerunge-Hudler Christian Vokuhl Winand N M Dinjens Iver Petersen Michel Mittelbronn Adrian Cuevas-Bourdier Rolf Buslei Stefan M Pfister Uta Flucke Gunhild Mechtersheimer Thomas Mentzel Andreas von Deimling

Clin Sarcoma Res 2019 14;9. Epub 2019 Feb 14.

2Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120 Heidelberg, Baden-Württemberg Germany.

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February 2019

Clinical evaluation of a dedicated next generation sequencing panel for routine glioma diagnostics.

Authors:
Nathalie E Synhaeve Martin J van den Bent Pim J French Winand N M Dinjens Peggy N Atmodimedjo Johan M Kros R Verdijk Clemens M F Dirven Hendrikus J Dubbink

Acta Neuropathol Commun 2018 11 23;6(1):126. Epub 2018 Nov 23.

Department of Pathology, Brain Tumor Center at Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

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November 2018

Functional Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects.

Authors:
Titia G Meijer Nicole S Verkaik Anieta M Sieuwerts Job van Riet Kishan A T Naipal Carolien H M van Deurzen Michael A den Bakker Hein F B M Sleddens Hendrikus-Jan Dubbink T Dorine den Toom Winand N M Dinjens Esther Lips Petra M Nederlof Marcel Smid Harmen J G van de Werken Roland Kanaar John W M Martens Agnes Jager Dik C van Gent

Clin Cancer Res 2018 12 23;24(24):6277-6287. Epub 2018 Aug 23.

Department of Molecular Genetics and Oncode Institute, Erasmus MC University Medical Center Rotterdam, the Netherlands.

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December 2018

Routine Molecular Analysis for Lynch Syndrome Among Adenomas or Colorectal Cancer Within a National Screening Program.

Authors:
Anne Goverde Anja Wagner Marco J Bruno Robert M W Hofstra Michael Doukas Marcel M van der Weiden Hendrikus J Dubbink Winand N M Dinjens Manon C W Spaander

Gastroenterology 2018 11 29;155(5):1410-1415. Epub 2018 Jul 29.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, the Netherlands. Electronic address:

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November 2018

Novel V834L Germline Mutation Associated With Familial Lung Adenocarcinoma.

Authors:
Cor van der Leest Anja Wagner Rute M Pedrosa Joachim G Aerts Winand N M Dinjens Hendrikus J Dubbink

JCO Precis Oncol 2018 16;2. Epub 2018 Jul 16.

and Amphia Ziekenhuis, Breda; and and Erasmus University Medical Center, Rotterdam, Netherlands.

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July 2018

Prognostic relevance of mutations and copy number alterations assessed with targeted next generation sequencing in IDH mutant grade II glioma.

Authors:
Maarten M J Wijnenga Pim J French Hendrikus J Dubbink Winand N M Dinjens Peggy N Atmodimedjo Johan M Kros Ruth Fleischeuer Clemens M F Dirven Arnaud J P E Vincent Martin J van den Bent

J Neurooncol 2018 Sep 16;139(2):349-357. Epub 2018 Apr 16.

Department of Neurology, Brain Tumor Center at Erasmus MC Cancer Institute, PO Box 5201, 3008AE, Rotterdam, The Netherlands.

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September 2018