Winand N M Dinjens

Winand N M Dinjens

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Winand N M Dinjens

Winand N M Dinjens

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Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification.

Authors:
Mieke R Van Bockstal Marie Colombe Agahozo Ronald van Marion Peggy N Atmodimedjo Hein F B M Sleddens Winand N M Dinjens Lindy L Visser Esther H Lips Jelle Wesseling Carolien H M van Deurzen

Mol Oncol 2020 Feb 14. Epub 2020 Feb 14.

Department of Pathology, Erasmus MC Cancer Institute Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/1878-0261.12650DOI Listing
February 2020

Development of esophageal squamous cell cancer in patients with FAMMM syndrome: Two clinical reports.

Authors:
Berend J van der Wilk Bo J Noordman Peggy N Atmodimedjo Winand N M Dinjens Robert J F Laheij Anja Wagner Bas P L Wijnhoven J Jan B van Lanschot

Eur J Med Genet 2020 Jan 7:103840. Epub 2020 Jan 7.

Department of Surgery, Erasmus MC - University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.ejmg.2020.103840DOI Listing
January 2020

Implementation of Novel Molecular Biomarkers for Non-small Cell Lung Cancer in the Netherlands: How to Deal With Increasing Complexity.

Authors:
Daan van den Broek T Jeroen N Hiltermann Bonne Biesma Winand N M Dinjens Nils A 't Hart John W J Hinrichs Mathie P G Leers Kim Monkhorst Matthijs van Oosterhout Volkher Scharnhorst Ed Schuuring Ernst-Jan M Speel Michel M van den Heuvel Ron H N van Schaik Jan von der Thüsen Stefan M Willems Leonie de Visser Marjolijn J L Ligtenberg

Front Oncol 2019 22;9:1521. Epub 2020 Jan 22.

Department of Human Genetics, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fonc.2019.01521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987414PMC
January 2020

Phenotype or Genotype: Decision-Making Dilemmas in Hepatocellular Adenoma.

Authors:
Anne J Klompenhouwer Maarten G J Thomeer Winand N M Dinjens Robert A de Man Jan N M Ijzermans Michail Doukas

Hepatology 2019 Nov 12;70(5):1866-1868. Epub 2019 Aug 12.

Department of Pathology, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1002/hep.30812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899780PMC
November 2019

Recommendations for the clinical interpretation and reporting of copy number gains using gene panel NGS analysis in routine diagnostics.

Authors:
Astrid Eijkelenboom Bastiaan B J Tops Anke van den Berg Adrianus J C van den Brule Winand N M Dinjens Hendrikus J Dubbink Arja Ter Elst Willemina R R Geurts-Giele Patricia J T A Groenen Floris H Groenendijk Daniëlle A M Heideman Manon M H Huibers Cornelis J J Huijsmans Judith W M Jeuken Léon C van Kempen Esther Korpershoek Leonie I Kroeze Wendy W J de Leng Carel J M van Noesel Ernst-Jan M Speel Maartje J Vogel Tom van Wezel Petra M Nederlof Ed Schuuring Marjolijn J L Ligtenberg

Virchows Arch 2019 Jun 19;474(6):673-680. Epub 2019 Mar 19.

Department of Pathology, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00428-019-02555-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581937PMC
June 2019

PIK3CA mutations in ductal carcinoma in situ and adjacent invasive breast cancer.

Authors:
Marie Colombe Agahozo Anieta M Sieuwerts S Charlane Doebar Esther I Verhoef Corine M Beaufort Kirsten Ruigrok-Ritstier Vanja de Weerd Hein F B M Sleddens Winand N M Dinjens John W M Martens Carolien H M van Deurzen

Endocr Relat Cancer 2019 May;26(5):471-482

Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1530/ERC-19-0019DOI Listing
May 2019

Correction: Functional Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects.

Authors:
Titia G Meijer Nicole S Verkaik Anieta M Sieuwerts Job van Riet Kishan A T Naipal Carolien H M van Deurzen Michael A den Bakker Hein F B M Sleddens Hendrikus-Jan Dubbink T Dorine den Toom Winand N M Dinjens Esther Lips Petra M Nederlof Marcel Smid Harmen J G van de Werken Roland Kanaar John W M Martens Agnes Jager Dik C van Gent

Clin Cancer Res 2019 May;25(9):2935

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http://dx.doi.org/10.1158/1078-0432.CCR-19-0936DOI Listing
May 2019

Estrogen receptor variants in ER-positive basal-type breast cancers responding to therapy like ER-negative breast cancers.

Authors:
Floris H Groenendijk Tina Treece Erin Yoder Paul Baron Peter Beitsch William Audeh Winand N M Dinjens Rene Bernards Pat Whitworth

NPJ Breast Cancer 2019 18;5:15. Epub 2019 Apr 18.

Nashville Breast Center, Nashville, TN USA.

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http://dx.doi.org/10.1038/s41523-019-0109-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472385PMC
April 2019

Molecular Alterations in Dog Pheochromocytomas and Paragangliomas.

Authors:
Esther Korpershoek Daphne A E R Dieduksman Guy C M Grinwis Michael J Day Claudia E Reusch Monika Hilbe Federico Fracassi Niels M G Krol André G Uitterlinden Annelies de Klein Bert Eussen Hans Stoop Ronald R de Krijger Sara Galac Winand N M Dinjens

Cancers (Basel) 2019 Apr 30;11(5). Epub 2019 Apr 30.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.

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http://dx.doi.org/10.3390/cancers11050607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563419PMC
April 2019

Genome-wide methylation profiling and copy number analysis in atypical fibroxanthomas and pleomorphic dermal sarcomas indicate a similar molecular phenotype.

Authors:
Christian Koelsche Damian Stichel Klaus G Griewank Daniel Schrimpf David E Reuss Melanie Bewerunge-Hudler Christian Vokuhl Winand N M Dinjens Iver Petersen Michel Mittelbronn Adrian Cuevas-Bourdier Rolf Buslei Stefan M Pfister Uta Flucke Gunhild Mechtersheimer Thomas Mentzel Andreas von Deimling

Clin Sarcoma Res 2019 14;9. Epub 2019 Feb 14.

2Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120 Heidelberg, Baden-Württemberg Germany.

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https://clinicalsarcomaresearch.biomedcentral.com/articles/1
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http://dx.doi.org/10.1186/s13569-019-0113-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375211PMC
February 2019

Functional Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects.

Authors:
Titia G Meijer Nicole S Verkaik Anieta M Sieuwerts Job van Riet Kishan A T Naipal Carolien H M van Deurzen Michael A den Bakker Hein F B M Sleddens Hendrikus-Jan Dubbink T Dorine den Toom Winand N M Dinjens Esther Lips Petra M Nederlof Marcel Smid Harmen J G van de Werken Roland Kanaar John W M Martens Agnes Jager Dik C van Gent

Clin Cancer Res 2018 12 23;24(24):6277-6287. Epub 2018 Aug 23.

Department of Molecular Genetics and Oncode Institute, Erasmus MC University Medical Center Rotterdam, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0063DOI Listing
December 2018

Routine Molecular Analysis for Lynch Syndrome Among Adenomas or Colorectal Cancer Within a National Screening Program.

Authors:
Anne Goverde Anja Wagner Marco J Bruno Robert M W Hofstra Michael Doukas Marcel M van der Weiden Hendrikus J Dubbink Winand N M Dinjens Manon C W Spaander

Gastroenterology 2018 11 29;155(5):1410-1415. Epub 2018 Jul 29.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183481
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http://dx.doi.org/10.1053/j.gastro.2018.07.029DOI Listing
November 2018

Clinical evaluation of a dedicated next generation sequencing panel for routine glioma diagnostics.

Authors:
Nathalie E Synhaeve Martin J van den Bent Pim J French Winand N M Dinjens Peggy N Atmodimedjo Johan M Kros R Verdijk Clemens M F Dirven Hendrikus J Dubbink

Acta Neuropathol Commun 2018 11 23;6(1):126. Epub 2018 Nov 23.

Department of Pathology, Brain Tumor Center at Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/s40478-018-0633-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251173PMC
November 2018

Prognostic relevance of mutations and copy number alterations assessed with targeted next generation sequencing in IDH mutant grade II glioma.

Authors:
Maarten M J Wijnenga Pim J French Hendrikus J Dubbink Winand N M Dinjens Peggy N Atmodimedjo Johan M Kros Ruth Fleischeuer Clemens M F Dirven Arnaud J P E Vincent Martin J van den Bent

J Neurooncol 2018 Sep 16;139(2):349-357. Epub 2018 Apr 16.

Department of Neurology, Brain Tumor Center at Erasmus MC Cancer Institute, PO Box 5201, 3008AE, Rotterdam, The Netherlands.

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http://link.springer.com/10.1007/s11060-018-2867-8
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http://dx.doi.org/10.1007/s11060-018-2867-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096891PMC
September 2018

Excluding Lynch syndrome in a female patient with metachronous DNA mismatch repair deficient colon- and ovarian cancer.

Authors:
Stijn Crobach Anne M L Jansen Marjolein J L Ligtenberg Marije Koopmans Maartje Nielsen Frederik J Hes Juul T Wijnen Winand N M Dinjens Tom van Wezel Hans Morreau

Fam Cancer 2018 07;17(3):415-420

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10689-017-0055-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999177PMC
July 2018

A novel tissue-based ß-catenin gene and immunohistochemical analysis to exclude familial adenomatous polyposis among children with hepatoblastoma tumors.

Authors:
Hendrikus J Dubbink Iris H I M Hollink Carolina Avenca Valente Wenhui Wang Pengyu Liu Michail Doukas Max M van Noesel Winand N M Dinjens Anja Wagner Ron Smits

Pediatr Blood Cancer 2018 06 15;65(6):e26991. Epub 2018 Feb 15.

Gastroenterology and Hepatology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands.

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http://doi.wiley.com/10.1002/pbc.26991
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http://dx.doi.org/10.1002/pbc.26991DOI Listing
June 2018

SNPitty: An Intuitive Web Application for Interactive B-Allele Frequency and Copy Number Visualization of Next-Generation Sequencing Data.

Authors:
Job van Riet Niels M G Krol Peggy N Atmodimedjo Erwin Brosens Wilfred F J van IJcken Maurice P H M Jansen John W M Martens Leendert H Looijenga Guido Jenster Hendrikus J Dubbink Winand N M Dinjens Harmen J G van de Werken

J Mol Diagn 2018 03 2;20(2):166-176. Epub 2018 Jan 2.

Cancer Computational Biology Center, Erasmus MC, University Medical Center, Rotterdam, the Netherlands; Department of Urology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2017.11.011DOI Listing
March 2018

Expression of Contactin 4 Is Associated With Malignant Behavior in Pheochromocytomas and Paragangliomas.

Authors:
Lucie Evenepoel Francien H van Nederveen Lindsey Oudijk Thomas G Papathomas David F Restuccia Eric J T Belt Wouter W de Herder Richard A Feelders Gaston J H Franssen Marc Hamoir Dominique Maiter Hans K Ghayee Jerry W Shay Aurel Perren Henri J L M Timmers Susanne van Eeden Laurent Vroonen Selda Aydin Mercedes Robledo Miikka Vikkula Ronald R de Krijger Winand N M Dinjens Alexandre Persu Esther Korpershoek

J Clin Endocrinol Metab 2018 01;103(1):46-55

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1210/jc.2017-01314DOI Listing
January 2018

The impact of surgery in molecularly defined low-grade glioma: an integrated clinical, radiological, and molecular analysis.

Authors:
Maarten M J Wijnenga Pim J French Hendrikus J Dubbink Winand N M Dinjens Peggy N Atmodimedjo Johan M Kros Marion Smits Renske Gahrmann Geert-Jan Rutten Jeroen B Verheul Ruth Fleischeuer Clemens M F Dirven Arnaud J P E Vincent Martin J van den Bent

Neuro Oncol 2018 01;20(1):103-112

Department of Neurology, Erasmus University Medical Center (Erasmus MC) Cancer Institute, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1093/neuonc/nox176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761503PMC
January 2018

Molecular and clinical heterogeneity of adult diffuse low-grade IDH wild-type gliomas: assessment of TERT promoter mutation and chromosome 7 and 10 copy number status allows superior prognostic stratification.

Authors:
Maarten M J Wijnenga Hendrikus J Dubbink Pim J French Nathalie E Synhaeve Winand N M Dinjens Peggy N Atmodimedjo Johan M Kros Clemens M F Dirven Arnaud J P E Vincent Martin J van den Bent

Acta Neuropathol 2017 Dec 19;134(6):957-959. Epub 2017 Oct 19.

Department of Neurology, Brain Tumor Center at Erasmus MC Cancer Institute, PO Box 5201, 3008AE, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-017-1781-zDOI Listing
December 2017

Pattern of p53 protein expression is predictive for survival in chemoradiotherapy-naive esophageal adenocarcinoma.

Authors:
Fiebo J C Ten Kate Lucia Suzuki Lambert C J Dorssers Winand N M Dinjens David T W Jones Daan Nieboer Michael Doukas J Jan B Van Lanschot Bas P L Wijnhoven Leendert H J Looijenga Katharina Biermann

Oncotarget 2017 Nov 24;8(61):104123-104135. Epub 2017 Oct 24.

Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.18632/oncotarget.22021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732792PMC
November 2017

Interim results from the CATNON trial (EORTC study 26053-22054) of treatment with concurrent and adjuvant temozolomide for 1p/19q non-co-deleted anaplastic glioma: a phase 3, randomised, open-label intergroup study.

Authors:
Martin J van den Bent Brigitta Baumert Sara C Erridge Michael A Vogelbaum Anna K Nowak Marc Sanson Alba Ariela Brandes Paul M Clement Jean Francais Baurain Warren P Mason Helen Wheeler Olivier L Chinot Sanjeev Gill Matthew Griffin David G Brachman Walter Taal Roberta Rudà Michael Weller Catherine McBain Jaap Reijneveld Roelien H Enting Damien C Weber Thierry Lesimple Susan Clenton Anja Gijtenbeek Sarah Pascoe Ulrich Herrlinger Peter Hau Frederic Dhermain Irene van Heuvel Roger Stupp Ken Aldape Robert B Jenkins Hendrikus Jan Dubbink Winand N M Dinjens Pieter Wesseling Sarah Nuyens Vassilis Golfinopoulos Thierry Gorlia Wolfgang Wick Johan M Kros

Lancet 2017 Oct 8;390(10103):1645-1653. Epub 2017 Aug 8.

Department of Pathology, Brain Tumour Centre at Erasmus MC Cancer Institute, Rotterdam, Netherlands.

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http://dx.doi.org/10.1016/S0140-6736(17)31442-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806535PMC
October 2017

Identification of Mutations in Cell-Free Circulating Tumor DNA in Adrenocortical Carcinoma: A Case Series.

Authors:
Sara G Creemers Esther Korpershoek Peggy N Atmodimedjo Winand N M Dinjens Peter M van Koetsveld Richard A Feelders Leo J Hofland

J Clin Endocrinol Metab 2017 10;102(10):3611-3615

Division of Endocrinology, Department of Internal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam 3000 CA, The Netherlands.

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http://dx.doi.org/10.1210/jc.2017-00174DOI Listing
October 2017

Somatic Tumor Mutations Detected by Targeted Next Generation Sequencing in Minute Amounts of Serum-Derived Cell-Free DNA.

Authors:
Marjolein J A Weerts Ronald van Marion Jean C A Helmijr Corine M Beaufort Niels M G Krol Anita M A C Trapman-Jansen Winand N M Dinjens Stefan Sleijfer Maurice P H M Jansen John W M Martens

Sci Rep 2017 05 18;7(1):2136. Epub 2017 May 18.

Erasmus MC Cancer Institute, Department of Medical Oncology and Cancer Genomics Netherlands, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41598-017-02388-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437051PMC
May 2017

Molecular clonality analysis of esophageal adenocarcinoma by multiregion sequencing of tumor samples.

Authors:
Anna M J van Nistelrooij Ronald van Marion Linetta B Koppert Katharina Biermann Manon C W Spaander Hugo W Tilanus J Jan B van Lanschot Bas P L Wijnhoven Winand N M Dinjens

BMC Res Notes 2017 Apr 4;10(1):144. Epub 2017 Apr 4.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13104-017-2456-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379534PMC
April 2017

Distinct Patterns of Somatic Mosaicism in the APC Gene in Neoplasms From Patients With Unexplained Adenomatous Polyposis.

Authors:
Anne M L Jansen Stijn Crobach Willemina R R Geurts-Giele Brendy E W M van den Akker Marina Ventayol Garcia Dina Ruano Maartje Nielsen Carli M J Tops Juul T Wijnen Frederik J Hes Tom van Wezel Winand N M Dinjens Hans Morreau

Gastroenterology 2017 02 2;152(3):546-549.e3. Epub 2016 Nov 2.

Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.10.040DOI Listing
February 2017

Molecular determination of the clonal relationships between multiple tumors in BRCA1/2-associated breast and/or ovarian cancer patients is clinically relevant.

Authors:
Willemina R R Geurts-Giele Victorien M T van Verschuer Carolien H M van Deurzen Paul J van Diest Rute M S M Pedrosa J Margriet Collée Linetta B Koppert Caroline Seynaeve Winand N M Dinjens

Mod Pathol 2017 01 9;30(1):15-25. Epub 2016 Sep 9.

Department of Pathology, Erasmus Medical Center Cancer Institute, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/modpathol.2016.145DOI Listing
January 2017

Sarcomatoid adrenocortical carcinoma: a comprehensive pathological, immunohistochemical, and targeted next-generation sequencing analysis.

Authors:
Thomas G Papathomas Eleonora Duregon Esther Korpershoek David F Restuccia Ronald van Marion Rocco Cappellesso Nathalie Sturm Giulio Rossi Antonella Coli Nicola Zucchini Hans Stoop Wolter Oosterhuis Laura Ventura Marco Volante Ambrogio Fassina Winand N M Dinjens Mauro Papotti Ronald R de Krijger

Hum Pathol 2016 12 31;58:113-122. Epub 2016 Aug 31.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam 3015 GE, The Netherlands; Department of Pathology, Reinier de Graaf Hospital, Delft 2625, AD, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2016.08.006DOI Listing
December 2016

IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study.

Authors:
Yunlei Li Jessica G C A M Buijs-Gladdines Kirsten Canté-Barrett Andrew P Stubbs Eric M Vroegindeweij Willem K Smits Ronald van Marion Winand N M Dinjens Martin Horstmann Roland P Kuiper Rogier C Buijsman Guido J R Zaman Peter J van der Spek Rob Pieters Jules P P Meijerink

PLoS Med 2016 Dec 20;13(12):e1002200. Epub 2016 Dec 20.

Department of Pediatric Oncology/Hematology, Erasmus Medical Center/Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1371/journal.pmed.1002200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172551PMC
December 2016

Cost-effectiveness of routine screening for Lynch syndrome in colorectal cancer patients up to 70 years of age.

Authors:
Celine H M Leenen Anne Goverde Esther W de Bekker-Grob Anja Wagner Margot G F van Lier Manon C W Spaander Marco J Bruno Carli M Tops Ans M W van den Ouweland Hendrikus J Dubbink Ernst J Kuipers Winand N M Dinjens Monique E van Leerdam Ewout W Steyerberg

Genet Med 2016 10 3;18(10):966-73. Epub 2016 Mar 3.

Department of Public Health, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/gim.2015.206DOI Listing
October 2016

Tissue inhibitor of metalloproteinase-3 (TIMP3) expression decreases during melanoma progression and inhibits melanoma cell migration.

Authors:
Asha M Das Michiel Bolkestein Thom van der Klok Charlotte M C Oude Ophuis Cindy E Vermeulen Joost A P Rens Winand N M Dinjens Peggy N Atmodimedjo Cornelis Verhoef Senada Koljenović Ron Smits Timo L M Ten Hagen Alexander M M Eggermont

Eur J Cancer 2016 10 11;66:34-46. Epub 2016 Aug 11.

Department of Surgical Oncology, Erasmus Medical Center, Rotterdam, The Netherlands; Gustave Roussy Cancer Campus Grand Paris, Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.06.020DOI Listing
October 2016

Diagnostic Detection of Allelic Losses and Imbalances by Next-Generation Sequencing: 1p/19q Co-Deletion Analysis of Gliomas.

Authors:
Hendrikus J Dubbink Peggy N Atmodimedjo Ronald van Marion Niels M G Krol Peter H J Riegman Johan M Kros Martin J van den Bent Winand N M Dinjens

J Mol Diagn 2016 09 25;18(5):775-786. Epub 2016 Jul 25.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jmoldx.2016.06.002DOI Listing
September 2016

An International Ki67 Reproducibility Study in Adrenal Cortical Carcinoma.

Authors:
Thomas G Papathomas Eugenio Pucci Thomas J Giordano Hao Lu Eleonora Duregon Marco Volante Mauro Papotti Ricardo V Lloyd Arthur S Tischler Francien H van Nederveen Vania Nose Lori Erickson Ozgur Mete Sylvia L Asa John Turchini Anthony J Gill Xavier Matias-Guiu Kassiani Skordilis Timothy J Stephenson Frédérique Tissier Richard A Feelders Marcel Smid Alex Nigg Esther Korpershoek Peter J van der Spek Winand N M Dinjens Andrew P Stubbs Ronald R de Krijger

Am J Surg Pathol 2016 Apr;40(4):569-76

Departments of *Pathology ∥Bioinformatics ¶¶¶Medical Oncology ∥∥∥Internal Medicine, Division of Endocrinology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam ††Laboratory for Pathology, PAL Dordrecht, Dordrecht ###Department of Pathology, Reinier de Graaf Hospital, Delft ****Department of Pathology, University Medical Center Utrecht, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands †Department of Histopathology, King's College Hospital, London ***Department of Pathology, University Hospitals Birmingham, Birmingham †††Department of Histopathology, Royal Hallamshire Hospital, Sheffield, UK ‡Department of Clinical and Molecular Medicine, Pathology Unit, Sant' Andrea Hospital, Sapienza University, Rome ¶Department of Oncology, University of Turin at San Luigi Hospital, Orbassano, Italy §Department of Pathology, Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, MI #Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI **Department of Pathology and Laboratory Medicine, Tufts Medical Center, Tufts University School of Medicine ‡‡Department of Pathology, Massachusetts General Hospital, Boston, MA §§Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN ∥∥Department of Pathology, University Health Network, University of Toronto, Toronto, ON, Canada ¶¶Department of Anatomical Pathology, Royal North Shore Hospital and University of Sydney, Sydney, NSW, Australia ##Department of Pathology and Molecular Genetics and Research Laboratory, Hospital Universitari Arnau de Vilanova, IRBLLEIDA, University of Lleida, Lleida, Spain ‡‡‡INSERM U1016 CNRS UMR8104, Institut Cochin, Paris Descartes University, Sorbonne Paris Cité §§§Department of Pathology, Pitié-Salpetrière Hospital, APHP, Pierre and Marie Curie Univers

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http://dx.doi.org/10.1097/PAS.0000000000000574DOI Listing
April 2016

Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial.

Authors:
Hendrikus J Dubbink Peggy N Atmodimedjo Johan M Kros Pim J French Marc Sanson Ahmed Idbaih Pieter Wesseling Roelien Enting Wim Spliet Cees Tijssen Winand N M Dinjens Thierry Gorlia Martin J van den Bent

Neuro Oncol 2016 Mar 9;18(3):388-400. Epub 2015 Sep 9.

Department of Pathology, Rotterdam, the Netherlands (H.J.D., P.N.A., J.M.K., W.N.M.D.); Department of Neurology, Erasmus Medical Center, Rotterdam, the Netherlands (P.J.F.); Groupe Hospitalier Pitie Salpetriere, Service de Neurologie Mazarin, Paris, France (M.S., A.I.); Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands (P.W.); Department of Pathology, Free University Medical Center, Amsterdam, the Netherlands (P.W.); Department of Neurology, University Medical Center Groningen, Groningen, the Netherlands (R.E.); Department of Pathology, UMCU, Utrecht, the Netherlands (W.S.); Department of Neurology, St. Elisabeth Hospital, Tilburg, the Netherlands (C.T.); European Organisation for Research and Treatment of Cancer Data Center, Brussels, Belgium (T.G.); Department of Neurology/Neuro-oncology, Erasmus MC Cancer Center, Rotterdam, the Netherlands (M.J.v.d.B.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767239PMC
March 2016

Early onset esophageal adenocarcinoma: a distinct molecular entity?

Authors:
Anna M J van Nistelrooij Ronald van Marion Katharina Biermann Manon C W Spaander J Jan B van Lanschot Bas P L Wijnhoven Winand N M Dinjens

Oncoscience 2016 1;3(1):42-8. Epub 2016 Feb 1.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, The Netherlands.

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http://dx.doi.org/10.18632/oncoscience.290DOI Listing
March 2016

Vascular pattern analysis for the prediction of clinical behaviour in pheochromocytomas and paragangliomas.

Authors:
Lindsey Oudijk Francien van Nederveen Cécile Badoual Frédérique Tissier Arthur S Tischler Marcel Smid José Gaal Charlotte Lepoutre-Lussey Anne-Paule Gimenez-Roqueplo Winand N M Dinjens Esther Korpershoek Ronald de Krijger Judith Favier

PLoS One 2015 20;10(3):e0121361. Epub 2015 Mar 20.

Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, F-75006 Paris, France; INSERM, UMR970, Paris Cardiovascular Research Center, F-75015 Paris, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368716PMC
February 2016

Complex MAX Rearrangement in a Family With Malignant Pheochromocytoma, Renal Oncocytoma, and Erythrocytosis.

Authors:
Esther Korpershoek Djamailys Koffy Bert H Eussen Lindsey Oudijk Thomas G Papathomas Francien H van Nederveen Eric J T Belt Gaston J H Franssen David F J Restuccia Niels M G Krol Rob B van der Luijt Richard A Feelders Rogier A Oldenburg Wilfred F J van Ijcken Annelies de Klein Wouter W de Herder Ronald R de Krijger Winand N M Dinjens

J Clin Endocrinol Metab 2016 Feb 15;101(2):453-60. Epub 2015 Dec 15.

Departments of Pathology (E.K., D.K., L.O., T.G.P., D.F.J.R., N.M.G.K., R.R.d.K., W.N.M.D.), Internal Medicine (R.A.F., W.W.d.H.), and Biomics (W.F.J.v.I.), Erasmus Medical Center Cancer Institute, University Medical Center, 3000 CA Rotterdam, The Netherlands; Departments of Clinical Genetics (B.H.E., R.A.O., A.d.K.), and Surgery (E.J.T.B., G.J.H.F.), Erasmus Medical Center Cancer Institute, University Medical Center, 3000 DR Rotterdam, The Netherlands; Department of Histopathology (T.G.P.), King's College Hospital, London, SE5 9RS, United Kingdom; Laboratory for Pathology (F.H.v.N.), Pathologisch Laboratorium Dordrecht, 3317 DA Dordrecht, The Netherlands; Division of Biomedical Genetics (R.B.v.d.L.), University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands; and Department of Pathology (R.R.d.K.), Reinier de Graaf Hospital, 2625 AD Delft, The Netherlands.

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http://dx.doi.org/10.1210/jc.2015-2592DOI Listing
February 2016

Association of TIMP3 expression with vessel density, macrophage infiltration and prognosis in human malignant melanoma.

Authors:
Asha M Das Senada Koljenović Charlotte M C Oude Ophuis Thom van der Klok Boris Galjart Alex L Nigg Wiggert A van Cappellen Vincent Noordhoek Hegt Winand N M Dinjens Peggy N Atmodimedjo Cindy E Vermeulen Cornelis Verhoef Alexander M M Eggermont Timo L M ten Hagen

Eur J Cancer 2016 Jan 17;53:135-43. Epub 2015 Dec 17.

Department of Surgical Oncology, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address:

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January 2016

Mitochondrial D310 mutation as clonal marker for solid tumors.

Authors:
Willemina R R Geurts-Giele Gerard H G K Gathier Peggy N Atmodimedjo Hendrikus J Dubbink Winand N M Dinjens

Virchows Arch 2015 Nov 15;467(5):595-602. Epub 2015 Aug 15.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656708PMC
November 2015

Succinate Dehydrogenase (SDH)-Deficient Pancreatic Neuroendocrine Tumor Expands the SDH-Related Tumor Spectrum.

Authors:
Nicolasine D Niemeijer Thomas G Papathomas Esther Korpershoek Ronald R de Krijger Lindsey Oudijk Hans Morreau Jean-Pierre Bayley Frederik J Hes Jeroen C Jansen Winand N M Dinjens Eleonora P M Corssmit

J Clin Endocrinol Metab 2015 Oct 10;100(10):E1386-93. Epub 2015 Aug 10.

Department of Endocrinology and Metabolic Diseases (N.D.N., E.P.M.C.), Leiden University Medical Center, 2300 RC Leiden, The Netherlands; Department of Pathology (T.G.P., E.K., L.O., W.N.M.D., R.R.d.K.) Erasmus Medical Center, 3015 CE Rotterdam, The Netherlands; Department of Pathology (R.R.d.K.), Reinier de Graaf Hospital, 2625 AD Delft, The Netherlands; and Departments of Pathology (H.M.), Human Genetics (J.P.B.), Clinical Genetics (F.J.H.), and Otorhinolaryngology (J.C.J.), Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1210/jc.2015-2689DOI Listing
October 2015

Toward an improved definition of the genetic and tumor spectrum associated with SDH germ-line mutations.

Authors:
Lucie Evenepoel Thomas G Papathomas Niels Krol Esther Korpershoek Ronald R de Krijger Alexandre Persu Winand N M Dinjens

Genet Med 2015 Aug 13;17(8):610-20. Epub 2014 Nov 13.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/gim.2014.162DOI Listing
August 2015

Single nucleotide polymorphisms in CRTC1 and BARX1 are associated with esophageal adenocarcinoma.

Authors:
Anna M J van Nistelrooij Hetty A G M van der Korput Linda Broer Ronald van Marion Mark I van Berge Henegouwen Carel J van Noesel Katharina Biermann Manon C W Spaander Hugo W Tilanus J Jan B van Lanschot Albert Hofman André G Uitterlinden Bas P L Wijnhoven Winand N M Dinjens

J Carcinog 2015 21;14. Epub 2015 May 21.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.4103/1477-3163.157441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453126PMC
June 2015

Treatment of large low-grade oligodendroglial tumors with upfront procarbazine, lomustine, and vincristine chemotherapy with long follow-up: a retrospective cohort study with growth kinetics.

Authors:
Walter Taal Carin C D van der Rijt Winand N M Dinjens Peter A E Sillevis Smitt Agnes A A C M Wertenbroek Jacoline E C Bromberg Irene van Heuvel Johan M Kros Martin J van den Bent

J Neurooncol 2015 Jan 26;121(2):365-72. Epub 2014 Oct 26.

Department of Neuro-Oncology/Neurology, Erasmus MC Cancer Institute, Erasmus MC University Medical Center, Groene Hilledijk 301, 3075 EA, Rotterdam, The Netherlands,

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http://dx.doi.org/10.1007/s11060-014-1641-9DOI Listing
January 2015

Guidelines on genetic evaluation and management of Lynch syndrome.

Authors:
Winand N M Dinjens Hendrikus J Dubbink Anja Wagner

Gastrointest Endosc 2015 Jan;81(1):243-4

Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.gie.2014.10.014DOI Listing
January 2015

Guidelines on genetic evaluation and management of Lynch syndrome.

Authors:
Winand N M Dinjens Hendrikus J Dubbink Anja Wagner

Am J Gastroenterol 2015 Jan;110(1):192-3

Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ajg.2014.329DOI Listing
January 2015

Somatic aberrations of mismatch repair genes as a cause of microsatellite-unstable cancers.

Authors:
Willemina R R Geurts-Giele Celine H M Leenen Hendrikus J Dubbink Isabelle C Meijssen Edward Post Hein F B M Sleddens Ernst J Kuipers Anne Goverde Ans M W van den Ouweland Margot G F van Lier Ewout W Steyerberg Monique E van Leerdam Anja Wagner Winand N M Dinjens

J Pathol 2014 Dec 30;234(4):548-59. Epub 2014 Sep 30.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Centre, Rotterdam, The Netherlands.

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http://doi.wiley.com/10.1002/path.4419
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December 2014

Automated Selection of Hotspots (ASH): enhanced automated segmentation and adaptive step finding for Ki67 hotspot detection in adrenal cortical cancer.

Authors:
Hao Lu Thomas G Papathomas David van Zessen Ivo Palli Ronald R de Krijger Peter J van der Spek Winand N M Dinjens Andrew P Stubbs

Diagn Pathol 2014 Nov 25;9:216. Epub 2014 Nov 25.

Department of Bioinformatics, Erasmus MC, University Medical Center, PO Box 2040, 3000, CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13000-014-0216-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261753PMC
November 2014

Aberrant SOX2 expression in colorectal cancers does not correlate with mucinous differentiation and gastric mucin MUC5AC expression.

Authors:
Lalini Raghoebir Katharina Biermann Marjon Buscop-van Kempen Hendrikus J Dubbink Winand N M Dinjens Remko Hersmus Leendert H J Looijenga Marco J Bruno Dick Tibboel Robbert J Rottier Ron Smits

Virchows Arch 2014 Oct 10;465(4):395-400. Epub 2014 Aug 10.

Department of Pediatric Surgery, Erasmus Medical Centre, Rotterdam, The Netherlands.

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October 2014

Paraganglioma and pheochromocytoma upon maternal transmission of SDHD mutations.

Authors:
Jean-Pierre Bayley Rogier A Oldenburg Jennifer Nuk Attje S Hoekstra Conny A van der Meer Esther Korpershoek Barbara McGillivray Eleonora P M Corssmit Winand N M Dinjens Ronald R de Krijger Peter Devilee Jeroen C Jansen Frederik J Hes

BMC Med Genet 2014 Oct 10;15:111. Epub 2014 Oct 10.

Department of Human Genetics, Leiden University Medical Center, PZ S-04, Leiden, 2300, RC, the Netherlands.

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http://dx.doi.org/10.1186/s12881-014-0111-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259087PMC
October 2014

Adrenal medullary hyperplasia is a precursor lesion for pheochromocytoma in MEN2 syndrome.

Authors:
Esther Korpershoek Bart-Jeroen Petri Edward Post Casper H J van Eijck Rogier A Oldenburg Eric J T Belt Wouter W de Herder Ronald R de Krijger Winand N M Dinjens

Neoplasia 2014 Oct 23;16(10):868-73. Epub 2014 Oct 23.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.neo.2014.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212248PMC
October 2014

Limited diagnostic value of microsatellite instability associated pathology features in colorectal cancer.

Authors:
Paul G van Putten Margot G F van Lier Mariska Hage Katharina Biermann Reinier H van Rijssel Pieter J Westenend Hans Morreau Ewout W Steyerberg Winand N M Dinjens Ernst J Kuipers Monique E van Leerdam J Han van Krieken

Fam Cancer 2014 Sep;13(3):351-9

Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, Room Ba-3, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands,

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September 2014

Telomerase reverse transcriptase promoter mutations in tumors originating from the adrenal gland and extra-adrenal paraganglia.

Authors:
Thomas G Papathomas Lindsey Oudijk Ellen C Zwarthoff Edward Post Floor A Duijkers Max M van Noesel Leo J Hofland Patrick J Pollard Eamonn R Maher David F Restuccia Richard A Feelders Gaston J H Franssen Henri J Timmers Stefan Sleijfer Wouter W de Herder Ronald R de Krijger Winand N M Dinjens Esther Korpershoek

Endocr Relat Cancer 2014 Aug 20;21(4):653-61. Epub 2014 Jun 20.

Department of PathologyJosephine Nefkens Institute, Erasmus MC, Rotterdam, The NetherlandsDepartment of Pediatric Oncology-HematologyErasmus MC-Sophia Children's Hospital, Rotterdam, The NetherlandsSector of EndocrinologyDepartment of Internal Medicine, Erasmus MC, Rotterdam, The NetherlandsCancer Biology and Metabolism GroupInstitute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UKDepartment of Medical GeneticsUniversity of Cambridge, Cambridge, UKDepartment of SurgeryErasmus MC, Rotterdam, The NetherlandsDivision of EndocrinologyDepartment of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The NetherlandsDepartment of Medical OncologyErasmus MC, Rotterdam, The NetherlandsDepartment of PathologyReinier de Graaf Hospital, Delft, The Netherlands

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http://erc.endocrinology-journals.org/content/early/2014/06/
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http://erc.endocrinology-journals.org/cgi/doi/10.1530/ERC-13
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http://dx.doi.org/10.1530/ERC-13-0429DOI Listing
August 2014

Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial.

Authors:
Walter Taal Hendrika M Oosterkamp Annemiek M E Walenkamp Hendrikus J Dubbink Laurens V Beerepoot Monique C J Hanse Jan Buter Aafke H Honkoop Dolf Boerman Filip Y F de Vos Winand N M Dinjens Roelien H Enting Martin J B Taphoorn Franchette W P J van den Berkmortel Rob L H Jansen Dieta Brandsma Jacoline E C Bromberg Irene van Heuvel René M Vernhout Bronno van der Holt Martin J van den Bent

Lancet Oncol 2014 Aug 15;15(9):943-53. Epub 2014 Jul 15.

Department of Neuro-oncology, Erasmus MC Cancer Institute, Rotterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(14)70314-6DOI Listing
August 2014

H-RAS mutations are restricted to sporadic pheochromocytomas lacking specific clinical or pathological features: data from a multi-institutional series.

Authors:
Lindsey Oudijk Ronald R de Krijger Ida Rapa Felix Beuschlein Aguirre A de Cubas Angelo P Dei Tos Winand N M Dinjens Esther Korpershoek Veronika Mancikova Massimo Mannelli Mauro Papotti Simona Vatrano Mercedes Robledo Marco Volante

J Clin Endocrinol Metab 2014 Jul 31;99(7):E1376-80. Epub 2014 Mar 31.

Department of Pathology (L.O., R.R.d.K., W.N.M.D., E.K.), Erasmus MC University Medical Center, 3015 CN Rotterdam, The Netherlands; Department of Pathology (R.R.d.K.), Reinier de Graaf Hospital, 2625 AD Delft, The Netherlands; Department of Oncology (I.R., M.P., S.V., M.V.), University of Turin at San Luigi Hospital, 10043 Orbassano, Turin, Italy; Endocrine Research Unit (F.B), Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, D-81675 Munich, Germany; Hereditary Endocrine Cancer Group (A.A.d.C., V.M., M.R.), Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain; Department of Pathology and Molecular Genetics (A.P.D.T.), General Hospital, 31100 Treviso, Italy; Department of Clinical Pathophysiology (M.M.), University of Florence, 50121 Florence Italy; and Centre for Biomedical Network Research on Rare Diseases (CIBERER) (M.R.), 28029 Madrid, Spain.

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http://dx.doi.org/10.1210/jc.2013-3879DOI Listing
July 2014

Next generation diagnostic molecular pathology: critical appraisal of quality assurance in Europe.

Authors:
Hendrikus J Dubbink Zandra C Deans Bastiaan B J Tops Folkert J van Kemenade S Koljenović Han J M van Krieken Willeke A M Blokx Winand N M Dinjens Patricia J T A Groenen

Mol Oncol 2014 Jun 18;8(4):830-9. Epub 2014 Mar 18.

Department of Pathology, Radboud University Medical Center, PO Box 9101, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2014.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528536PMC
June 2014

Hereditary Factors in Esophageal Adenocarcinoma.

Authors:
Anna M J van Nistelrooij Winand N M Dinjens Anja Wagner Manon C W Spaander J Jan B van Lanschot Bas P L Wijnhoven

Gastrointest Tumors 2014 Jun 9;1(2):93-8. Epub 2014 May 9.

Department of Surgery, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1159/000362575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645576PMC
June 2014

Functional analysis of MSH2 unclassified variants found in suspected Lynch syndrome patients reveals pathogenicity due to attenuated mismatch repair.

Authors:
Eva A L Wielders Jan Hettinger Rob Dekker C Marleen Kets Marjolijn J Ligtenberg Arjen R Mensenkamp Ans M W van den Ouweland Judith Prins Anja Wagner Winand N M Dinjens Hendrikus Jan Dubbink Liselotte P van Hest Fred Menko Frans Hogervorst Senno Verhoef Hein te Riele

J Med Genet 2014 Apr 5;51(4):245-53. Epub 2014 Feb 5.

Division of Biological Stress Response, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/jmedgenet-2013-101987DOI Listing
April 2014

Non-pheochromocytoma (PCC)/paraganglioma (PGL) tumors in patients with succinate dehydrogenase-related PCC-PGL syndromes: a clinicopathological and molecular analysis.

Authors:
Thomas G Papathomas Jose Gaal Eleonora P M Corssmit Lindsey Oudijk Esther Korpershoek Ketil Heimdal Jean-Pierre Bayley Hans Morreau Marieke van Dooren Konstantinos Papaspyrou Thomas Schreiner Torsten Hansen Per Arne Andresen David F Restuccia Ingrid van Kessel Geert J L H van Leenders Johan M Kros Leendert H J Looijenga Leo J Hofland Wolf Mann Francien H van Nederveen Ozgur Mete Sylvia L Asa Ronald R de Krijger Winand N M Dinjens

Eur J Endocrinol 2014 Jan 22;170(1):1-12. Epub 2013 Nov 22.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1530/EJE-13-0623DOI Listing
January 2014

Detection of spontaneous tumorigenic transformation during culture expansion of human mesenchymal stromal cells.

Authors:
Qiuwei Pan Suomi M G Fouraschen Petra E de Ruiter Winand N M Dinjens Jaap Kwekkeboom Hugo W Tilanus Luc J W van der Laan

Exp Biol Med (Maywood) 2014 Jan 13;239(1):105-15. Epub 2013 Nov 13.

Department of Gastroenterology & Hepatology, Erasmus MC-University Medical Center and Postgraduate School Molecular Medicine, Rotterdam NL-3015 CE, The Netherlands.

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http://dx.doi.org/10.1177/1535370213506802DOI Listing
January 2014

Successive B-cell lymphomas mostly reflect recurrences rather than unrelated primary lymphomas.

Authors:
Willemina R R Geurts-Giele Ingrid L M Wolvers-Tettero Winand N M Dinjens King H Lam Anton W Langerak

Am J Clin Pathol 2013 Jul;140(1):114-26

Dept. of Pathology, Josephine Nefkens Institute, Erasmus Medical Center, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1309/AJCPI14GXNWASVUZDOI Listing
July 2013

Defects in the DNA mismatch repair system do not contribute to the development of childhood wilms tumors.

Authors:
Heidi Segers Marry M van den Heuvel-Eibrink Ronald R de Krijger Rob Pieters Anja Wagner Winand N M Dinjens

Pediatr Dev Pathol 2013 Jan-Feb;16(1):14-9

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Dr. Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands.

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http://dx.doi.org/10.2350/12-09-1249-OADOI Listing
June 2013

CD44 and OTP are strong prognostic markers for pulmonary carcinoids.

Authors:
Dorian R A Swarts Mieke E R Henfling Leander Van Neste Robert-Jan van Suylen Anne-Marie C Dingemans Winand N M Dinjens Annick Haesevoets Martina Rudelius Erik Thunnissen Marco Volante Wim Van Criekinge Manon van Engeland Frans C S Ramaekers Ernst-Jan M Speel

Clin Cancer Res 2013 Apr 26;19(8):2197-207. Epub 2013 Feb 26.

Department of Molecular Cell Biology, GROW-School for Oncology & Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.

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April 2013

Three-gene immunohistochemical panel adds to clinical staging algorithms to predict prognosis for patients with esophageal adenocarcinoma.

Authors:
Chin-Ann J Ong Joel Shapiro Katie S Nason Jon M Davison Xinxue Liu Caryn Ross-Innes Maria O'Donovan Winand N M Dinjens Katharina Biermann Nicholas Shannon Susannah Worster Laura K E Schulz James D Luketich Bas P L Wijnhoven Richard H Hardwick Rebecca C Fitzgerald

J Clin Oncol 2013 Apr 18;31(12):1576-82. Epub 2013 Mar 18.

Hutchison/MRC Research Centre, Cambridge, UK.

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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2012.45.9636
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625712PMC
April 2013

SDHA mutations in adult and pediatric wild-type gastrointestinal stromal tumors.

Authors:
Lindsey Oudijk José Gaal Esther Korpershoek Francien H van Nederveen Lorna Kelly Gaia Schiavon Jaap Verweij Ron H J Mathijssen Michael A den Bakker Rogier A Oldenburg Rosa L E van Loon Maureen J O'Sullivan Ronald R de Krijger Winand N M Dinjens

Mod Pathol 2013 Mar 23;26(3):456-63. Epub 2012 Nov 23.

Department of Pathology, Erasmus MC, University Medical Center Rotterdam, Josephine Nefkens Institute, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/modpathol.2012.186DOI Listing
March 2013

Prevalence of c-KIT mutations in gonadoblastoma and dysgerminomas of patients with disorders of sex development (DSD) and ovarian dysgerminomas.

Authors:
Remko Hersmus Hans Stoop Gert Jan van de Geijn Ronak Eini Katharina Biermann J Wolter Oosterhuis Catharina Dhooge Dominik T Schneider Isabelle C Meijssen Winand N M Dinjens Hendrikus Jan Dubbink Stenvert L S Drop Leendert H J Looijenga

PLoS One 2012 28;7(8):e43952. Epub 2012 Aug 28.

Department of Pathology, Erasmus MC - University Medical Center Rotterdam, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429439PMC
February 2013

Molecular diagnostics of a single multifocal non-small cell lung cancer case using targeted next generation sequencing.

Authors:
Willemina R R Geurts-Giele Albertina W Dirkx-van der Velden Natascha M M T Bartalits Leon C Verhoog Wessel E J J Hanselaar Winand N M Dinjens

Virchows Arch 2013 Feb 22;462(2):249-54. Epub 2012 Dec 22.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00428-012-1346-4DOI Listing
February 2013

Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951.

Authors:
Martin J van den Bent Alba A Brandes Martin J B Taphoorn Johan M Kros Mathilde C M Kouwenhoven Jean-Yves Delattre Hans J J A Bernsen Marc Frenay Cees C Tijssen Wolfgang Grisold László Sipos Roelien H Enting Pim J French Winand N M Dinjens Charles J Vecht Anouk Allgeier Denis Lacombe Thierry Gorlia Khê Hoang-Xuan

J Clin Oncol 2013 Jan 15;31(3):344-50. Epub 2012 Oct 15.

Neuro-Oncology Unit, Erasmus MC-Daniel den Hoed Cancer Center, PO Box 5201, 3008AE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1200/JCO.2012.43.2229DOI Listing
January 2013

Trp53 inactivation leads to earlier phaeochromocytoma formation in pten knockout mice.

Authors:
Esther Korpershoek Nanne K Kloosterhof Angelique Ziel-van der Made Hanneke Korsten Lindsey Oudijk Jan Trapman Winand N M Dinjens Ronald R de Krijger

Endocr Relat Cancer 2012 Dec 30;19(6):731-40. Epub 2012 Oct 30.

Department of Pathology, Josephine Nefkens Institute, Erasmus Medical Centre, CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1530/ERC-12-0088DOI Listing
December 2012

Identification of Familial Adenomatous Polyposis carriers among children with desmoid tumours.

Authors:
Anna A Kattentidt Mouravieva Ina R R Geurts-Giele Ronald R de Krijger Max M van Noesel Cees P van de Ven Ans M W van den Ouweland Joan N R Kromosoeto Winand N M Dinjens Hendrikus J Dubbink Ron Smits Anja Wagner

Eur J Cancer 2012 Aug 2;48(12):1867-74. Epub 2012 Feb 2.

Department of Clinical Genetics, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ejca.2012.01.004DOI Listing
August 2012

Prospective evaluation of molecular screening for Lynch syndrome in patients with endometrial cancer ≤ 70 years.

Authors:
Celine H M Leenen Margot G F van Lier Helena C van Doorn Monique E van Leerdam Sjarlot G Kooi Judith de Waard Robert F Hoedemaeker Ans M W van den Ouweland Sanne M Hulspas Hendrikus J Dubbink Ernst J Kuipers Anja Wagner Winand N M Dinjens Ewout W Steyerberg

Gynecol Oncol 2012 May 1;125(2):414-20. Epub 2012 Feb 1.

Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ygyno.2012.01.049DOI Listing
May 2012

Yield of routine molecular analyses in colorectal cancer patients ≤70 years to detect underlying Lynch syndrome.

Authors:
Margot G F van Lier Celine H M Leenen Anja Wagner Dewkoemar Ramsoekh Hendrikus J Dubbink Ans M W van den Ouweland Pieter J Westenend Eelco J R de Graaf Leonieke M M Wolters Wietske W Vrijland Ernst J Kuipers Monique E van Leerdam Ewout W Steyerberg Winand N M Dinjens

J Pathol 2012 Apr 17;226(5):764-74. Epub 2012 Jan 17.

Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/path.3963DOI Listing
April 2012

Mapping of homozygous deletions in verified esophageal adenocarcinoma cell lines and xenografts.

Authors:
Jurjen J Boonstra Ronald van Marion Hannie J C W Douben Jerry S Lanchbury Kirsten M Timms Victor Abkevich Hugo W Tilanus Annelies de Klein Winand N M Dinjens

Genes Chromosomes Cancer 2012 Mar 12;51(3):272-82. Epub 2011 Nov 12.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/gcc.20952DOI Listing
March 2012

SDHA immunohistochemistry detects germline SDHA gene mutations in apparently sporadic paragangliomas and pheochromocytomas.

Authors:
Esther Korpershoek Judith Favier José Gaal Nelly Burnichon Bram van Gessel Lindsey Oudijk Cécile Badoual Noémie Gadessaud Annabelle Venisse Jean-Pierre Bayley Marieke F van Dooren Wouter W de Herder Frédérique Tissier Pierre-François Plouin Francien H van Nederveen Winand N M Dinjens Anne-Paule Gimenez-Roqueplo Ronald R de Krijger

J Clin Endocrinol Metab 2011 Sep 13;96(9):E1472-6. Epub 2011 Jul 13.

Department of Pathology, Erasmus MC-University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2011-1043DOI Listing
September 2011

MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation.

Authors:
Floris H Groenendijk Walter Taal Hendrikus J Dubbink Cathleen R Haarloo Mathilde C Kouwenhoven Martin J van den Bent Johan M Kros Winand N M Dinjens

J Neurooncol 2011 Feb 1;101(3):405-17. Epub 2010 Jul 1.

Department of Pathology, Josephine Nefkens Institute, Be320a, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11060-010-0274-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024495PMC
February 2011

First-line temozolomide chemotherapy in progressive low-grade astrocytomas after radiotherapy: molecular characteristics in relation to response.

Authors:
Walter Taal Hendrikus J Dubbink Chris B L Zonnenberg Bernard A Zonnenberg Tjeerd J Postma Johanna M M Gijtenbeek Willem Boogerd Floris H Groenendijk Johan M Kros Mathilde C M Kouwenhoven Ronald van Marion Irene van Heuvel Bronno van der Holt Jacoline E C Bromberg Peter A E Sillevis Smitt Winand N M Dinjens Martin J van den Bent

Neuro Oncol 2011 Feb 21;13(2):235-41. Epub 2010 Dec 21.

Department of Neuro-oncology/Neurology, Erasmus MC, Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/neuonc/noq177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064627PMC
February 2011

SDHB immunohistochemistry: a useful tool in the diagnosis of Carney-Stratakis and Carney triad gastrointestinal stromal tumors.

Authors:
José Gaal Constantine A Stratakis J Aidan Carney Evan R Ball Esther Korpershoek Maya B Lodish Isaac Levy Paraskevi Xekouki Francien H van Nederveen Michael A den Bakker Maureen O'Sullivan Winand N M Dinjens Ronald R de Krijger

Mod Pathol 2011 Jan 1;24(1):147-51. Epub 2010 Oct 1.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://www.nature.com/doifinder/10.1038/modpathol.2010.185
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http://dx.doi.org/10.1038/modpathol.2010.185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415983PMC
January 2011

Functional polymorphisms associated with disease-free survival in resected carcinoma of the esophagus.

Authors:
Jurjen J Boonstra Ronald van Marion Hugo W Tilanus Winand N M Dinjens

J Gastrointest Surg 2011 Jan 5;15(1):48-56. Epub 2010 Oct 5.

Department of Surgery, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11605-010-1358-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023032PMC
January 2011

Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations.

Authors:
Katherine A Janeway Su Young Kim Maya Lodish Vânia Nosé Pierre Rustin José Gaal Patricia L M Dahia Bernadette Liegl Evan R Ball Margarita Raygada Angela H Lai Lorna Kelly Jason L Hornick Maureen O'Sullivan Ronald R de Krijger Winand N M Dinjens George D Demetri Cristina R Antonescu Jonathan A Fletcher Lee Helman Constantine A Stratakis

Proc Natl Acad Sci U S A 2011 Jan 20;108(1):314-8. Epub 2010 Dec 20.

Department of Pediatric Hematology-Oncology, Dana Farber Cancer Institute and Children's Hospital, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017134PMC
January 2011

Lymphatic micrometastases in patients with early esophageal adenocarcinoma.

Authors:
Brechtje A Grotenhuis Mark van Heijl Bas P L Wijnhoven Mark I van Berge Henegouwen Katharina Biermann Fiebo J W ten Kate Olivier R C Busch Winand N M Dinjens Hugo W Tilanus J Jan B van Lanschot

J Surg Oncol 2010 Dec;102(7):863-7

Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/jso.21719DOI Listing
December 2010

The pathogenesis of Barrett's metaplasia and the progression to esophageal adenocarcinoma.

Authors:
Brechtje A Grotenhuis J Jan B van Lanschot Winand N M Dinjens Bas P L Wijnhoven

Recent Results Cancer Res 2010 ;182:39-63

Department of Surgery, Erasmus MC, University Medical Center, 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/978-3-540-70579-6_4DOI Listing
October 2010

Intra-tumoral molecular heterogeneity in benign and malignant pheochromocytomas and extra-adrenal sympathetic paragangliomas.

Authors:
Esther Korpershoek Claudia K Stobbe Francien H van Nederveen Ronald R de Krijger Winand N M Dinjens

Endocr Relat Cancer 2010 Sep 25;17(3):653-62. Epub 2010 Jun 25.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1677/ERC-10-0072DOI Listing
September 2010

Mucinous carcinoid of the ovary: report of a case with metastasis in the contralateral ovary after ten years.

Authors:
Christien C M Buis Helena C van Doorn Winand N M Dinjens Patricia C Ewing

Rare Tumors 2010 Sep 30;2(3):e39. Epub 2010 Sep 30.

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http://dx.doi.org/10.4081/rt.2010.e39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994532PMC
September 2010

Barrett's oesophageal adenocarcinoma encompasses tumour-initiating cells that do not express common cancer stem cell markers.

Authors:
Brechtje A Grotenhuis Winand N M Dinjens Bas P L Wijnhoven Petra Sonneveld Andrea Sacchetti Patrick F Franken Herman van Dekken Hugo W Tilanus J Jan B van Lanschot Riccardo Fodde

J Pathol 2010 Aug;221(4):379-89

Department of Surgery, Josephine Nefkens Institute, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/path.2733DOI Listing
August 2010

Mutation of SDHB is a cause of hypoxia-related high-altitude paraganglioma.

Authors:
Nidia Y Cerecer-Gil Luis E Figuera Francisco J Llamas Mauricio Lara José G Escamilla Ruben Ramos Gerardo Estrada A Karim Hussain José Gaal Esther Korpershoek Ronald R de Krijger Winand N M Dinjens Peter Devilee Jean Pierre Bayley

Clin Cancer Res 2010 Aug 30;16(16):4148-54. Epub 2010 Jun 30.

Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Mexico.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-0637DOI Listing
August 2010

Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines.

Authors:
Antoinette Hollestelle Jord H A Nagel Marcel Smid Suzanne Lam Fons Elstrodt Marijke Wasielewski Ser Sue Ng Pim J French Justine K Peeters Marieke J Rozendaal Muhammad Riaz Daphne G Koopman Timo L M Ten Hagen Bertie H C G M de Leeuw Ellen C Zwarthoff Amina Teunisse Peter J van der Spek Jan G M Klijn Winand N M Dinjens Stephen P Ethier Hans Clevers Aart G Jochemsen Michael A den Bakker John A Foekens John W M Martens Mieke Schutte

Breast Cancer Res Treat 2010 May 11;121(1):53-64. Epub 2009 Jul 11.

Department of Medical Oncology, Josephine Nefkens Institute, Erasmus, The Netherlands.

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http://dx.doi.org/10.1007/s10549-009-0460-8DOI Listing
May 2010

On the advent of MSI testing of all colorectal cancers and a substantial part of other Lynch syndrome-related neoplasms.

Authors:
Winand N M Dinjens Monique E van Leerdam Anja Wagner

Expert Rev Mol Diagn 2010 May;10(4):381-4

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http://dx.doi.org/10.1586/erm.10.37DOI Listing
May 2010

SDHAF2 mutations in familial and sporadic paraganglioma and phaeochromocytoma.

Authors:
Jean-Pierre Bayley Henricus P M Kunst Alberto Cascon Maria Lourdes Sampietro José Gaal Esther Korpershoek Adolfo Hinojar-Gutierrez Henri J L M Timmers Lies H Hoefsloot Mario A Hermsen Carlos Suárez A Karim Hussain Annette H J T Vriends Frederik J Hes Jeroen C Jansen Carli M Tops Eleonora P Corssmit Peter de Knijff Jacques W M Lenders Cor W R J Cremers Peter Devilee Winand N M Dinjens Ronald R de Krijger Mercedes Robledo

Lancet Oncol 2010 Apr 11;11(4):366-72. Epub 2010 Jan 11.

Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/S1470-2045(10)70007-3DOI Listing
April 2010

Isocitrate dehydrogenase mutations are rare in pheochromocytomas and paragangliomas.

Authors:
José Gaal Nelly Burnichon Esther Korpershoek Isabelle Roncelin Jérôme Bertherat Pierre-François Plouin Ronald R de Krijger Anne-Paule Gimenez-Roqueplo Winand N M Dinjens

J Clin Endocrinol Metab 2010 Mar 13;95(3):1274-8. Epub 2009 Nov 13.

Department of Pathology, Josephine Nefkens Institute, Room Ae304, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2009-2170DOI Listing
March 2010

IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group.

Authors:
Martin J van den Bent Hendrikus J Dubbink Yannick Marie Alba A Brandes Martin J B Taphoorn Pieter Wesseling Marc Frenay Cees C Tijssen Denis Lacombe Ahmed Idbaih Ronald van Marion Johan M Kros Winand N M Dinjens Thierry Gorlia Marc Sanson

Clin Cancer Res 2010 Mar 16;16(5):1597-604. Epub 2010 Feb 16.

Dept Neuro-Oncology and Pathology, Daniel den Hoed Cancer Center and Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-2902DOI Listing
March 2010

Verification and unmasking of widely used human esophageal adenocarcinoma cell lines.

Authors:
Jurjen J Boonstra Ronald van Marion David G Beer Lin Lin Paula Chaves Catarina Ribeiro A Dias Pereira Lúcia Roque S Jane Darnton Nasser K Altorki David S Schrump David S Klimstra Laura H Tang James R Eshleman Hector Alvarez Yutaka Shimada Herman van Dekken Hugo W Tilanus Winand N M Dinjens

J Natl Cancer Inst 2010 Feb 14;102(4):271-4. Epub 2010 Jan 14.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/jnci/djp499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902814PMC
February 2010

A review on the molecular diagnostics of Lynch syndrome: a central role for the pathology laboratory.

Authors:
Margot G F van Lier Anja Wagner Monique E van Leerdam Katharina Biermann Ernst J Kuipers Ewout W Steyerberg Hendrikus Jan Dubbink Winand N M Dinjens

J Cell Mol Med 2010 Jan 19;14(1-2):181-97. Epub 2009 Nov 19.

Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1582-4934.2009.00977.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837620PMC
January 2010

TP53 mutation analysis of malignant peripheral nerve sheath tumors.

Authors:
Robert M Verdijk Michael A den Bakker Hendrikus J Dubbink Wim C J Hop Winand N M Dinjens Johan M Kros

J Neuropathol Exp Neurol 2010 Jan;69(1):16-26

Department of Pathology, Erasmus MC, University, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/NEN.0b013e3181c55d55DOI Listing
January 2010

MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951.

Authors:
Martin J van den Bent Hendrikus J Dubbink Marc Sanson Cathleen R van der Lee-Haarloo Monika Hegi Judith W M Jeuken Ahmed Ibdaih Alba A Brandes Martin J B Taphoorn Marc Frenay Denis Lacombe Thierry Gorlia Winand N M Dinjens Johan M Kros

J Clin Oncol 2009 Dec 9;27(35):5881-6. Epub 2009 Nov 9.

Department of Neuro-Oncology and Pathology, Daniel den Hoed Cancer Center and Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2009.24.1034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793037PMC
December 2009

Parasympathetic paragangliomas are part of the Von Hippel-Lindau syndrome.

Authors:
José Gaal Francien H van Nederveen Zoran Erlic Esther Korpershoek Rogier Oldenburg Carsten C Boedeker Udo Kontny Hartmut P Neumann Winand N M Dinjens Ronald R de Krijger

J Clin Endocrinol Metab 2009 Nov 6;94(11):4367-71. Epub 2009 Oct 6.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2009-1479DOI Listing
November 2009

An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis.

Authors:
Francien H van Nederveen José Gaal Judith Favier Esther Korpershoek Rogier A Oldenburg Elly M C A de Bruyn Hein F B M Sleddens Pieter Derkx Julie Rivière Hilde Dannenberg Bart-Jeroen Petri Paul Komminoth Karel Pacak Wim C J Hop Patrick J Pollard Massimo Mannelli Jean-Pierre Bayley Aurel Perren Stephan Niemann Albert A Verhofstad Adriaan P de Bruïne Eamonn R Maher Frédérique Tissier Tchao Méatchi Cécile Badoual Jérôme Bertherat Laurence Amar Despoina Alataki Eric Van Marck Francesco Ferrau Jerney François Wouter W de Herder Mark-Paul F M Vrancken Peeters Anne van Linge Jacques W M Lenders Anne-Paule Gimenez-Roqueplo Ronald R de Krijger Winand N M Dinjens

Lancet Oncol 2009 Aug 1;10(8):764-71. Epub 2009 Jul 1.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1016/S1470-2045(09)70164-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718191PMC
August 2009

Underutilization of microsatellite instability analysis in colorectal cancer patients at high risk for Lynch syndrome.

Authors:
Margot G F Van Lier Johannes H W De Wilt Jessie J M F Wagemakers Winand N M Dinjens Ronald A M Damhuis Anja Wagner Ernst J Kuipers Monique E Van Leerdam

Scand J Gastroenterol 2009 ;44(5):600-4

Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1080/00365520802706008DOI Listing
July 2009

Introduction of epithelial cells in the flap-graft interface during descemet stripping automated endothelial keratoplasty.

Authors:
Isabelle E Y Saelens Marjolijn C Bartels Gabriel Van Rij Winand N M Dinjens Cornelia M Mooy

Arch Ophthalmol 2009 Jul;127(7):936-7

Department of Ophthalmology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, the Netherlands.

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http://dx.doi.org/10.1001/archophthalmol.2009.143DOI Listing
July 2009

Deletion of exons 1a-2 of BRCA1: a rather frequent pathogenic abnormality.

Authors:
Ans M W van den Ouweland Winand N M Dinjens Lambert C J Dorssers Monique M van Veghel-Plandsoen Hennie T Brüggenwirth Caroline J Withagen-Hermans Johanna Margriet Collée Simon A Joosse Joan N R Terlouw-Kromosoeto Petra M Nederlof

Genet Test Mol Biomarkers 2009 Jun;13(3):399-406

Department of Clinical Genetics, Josephine Nefkens Institute, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1089/gtmb.2008.0155DOI Listing
June 2009

Microsatellite instability, mismatch repair deficiency, and BRAF mutation in treatment-resistant germ cell tumors.

Authors:
Friedemann Honecker Hendrik Wermann Frank Mayer Ad J M Gillis Hans Stoop Ruud J L M van Gurp Karin Oechsle Ewout Steyerberg Jörg Th Hartmann Winand N M Dinjens J Wolter Oosterhuis Carsten Bokemeyer Leendert H J Looijenga

J Clin Oncol 2009 May 16;27(13):2129-36. Epub 2009 Mar 16.

Department of Oncology, University Medical Center Hamburg- Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1200/JCO.2008.18.8623DOI Listing
May 2009

Array comparative genomic hybridization, expression array, and protein analysis of critical regions on chromosome arms 1q, 7q, and 8p in adenocarcinomas of the gastroesophageal junction.

Authors:
Herman van Dekken Hugo W Tilanus Wim C J Hop Winand N M Dinjens Josiane C Wink Kees J Vissers Ronald van Marion

Cancer Genet Cytogenet 2009 Feb;189(1):37-42

Department of Pathology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.cancergencyto.2008.08.018DOI Listing
February 2009