Publications by authors named "Wim Wuyts"

98Publications

Pathology of Idiopathic Pulmonary Fibrosis Assessed by a Combination of Microcomputed Tomography, Histology, and Immunohistochemistry.

Am J Pathol 2020 Dec 11;190(12):2427-2435. Epub 2020 Sep 11.

Centre for Heart and Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.ajpath.2020.09.001DOI Listing
December 2020

A New Pathogenic Variant in the TRIOBP Associated with Profound Deafness Is Remediable with Cochlear Implantation.

Audiol Neurootol 2020 Sep 2:1-9. Epub 2020 Sep 2.

Department of Otolaryngology and Head and Neck Surgery, University of Antwerp/Antwerp University Hospital, Antwerp, Belgium,

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http://dx.doi.org/10.1159/000508434DOI Listing
September 2020

Etiological Work-up in Referrals From Neonatal Hearing Screening: 20 Years of Experience.

Otol Neurotol 2020 Aug 5. Epub 2020 Aug 5.

Department of Medical Genetics, University of Antwerp.

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http://dx.doi.org/10.1097/MAO.0000000000002758DOI Listing
August 2020

Desquamative interstitial pneumonia: a systematic review of its features and outcomes.

Eur Respir Rev 2020 Jun 23;29(156). Epub 2020 Jun 23.

Dept of Respiratory Diseases and Allergy, Center for Rare Lung Diseases, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1183/16000617.0181-2019DOI Listing
June 2020

Towards the Essence of Progressiveness: Bringing Progressive Fibrosing Interstitial Lung Disease (PF-ILD) to the Next Stage.

J Clin Med 2020 Jun 3;9(6). Epub 2020 Jun 3.

Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.3390/jcm9061722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355916PMC
June 2020

Progressive lung fibrosis and mortality can occur in early systemic sclerosis patients without pulmonary abnormalities at baseline assessment.

Clin Rheumatol 2020 Nov 8;39(11):3393-3400. Epub 2020 May 8.

Division of Rheumatology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1007/s10067-020-05105-4DOI Listing
November 2020

Prognostic value of cardiovascular magnetic resonance in patients with biopsy-proven systemic sarcoidosis.

Eur Radiol 2020 Jul 12;30(7):3702-3710. Epub 2020 Mar 12.

Department of Radiology, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1007/s00330-020-06765-1DOI Listing
July 2020

Natural evolution of cardiac sarcoidosis in an asymptomatic patient: a case report.

Eur Heart J Case Rep 2019 Sep 5;3(3):ytz099. Epub 2019 Jul 5.

Department of Radiology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1093/ehjcr/ytz099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764548PMC
September 2019

Adams-Oliver syndrome caused by mutations of the EOGT gene.

Am J Med Genet A 2019 11 31;179(11):2246-2251. Epub 2019 Jul 31.

Institute of Human Genetics, University Hospital Magdeburg, Magdeburg, Germany.

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http://dx.doi.org/10.1002/ajmg.a.61313DOI Listing
November 2019

Granulomatous lung disease in two workers making light bulbs.

Am J Ind Med 2019 10 26;62(10):908-913. Epub 2019 Jul 26.

Department of Pulmonary Medicine, Clinic of Occupational and Environmental Medicine, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1002/ajim.23030DOI Listing
October 2019

Outcome of lung transplantation in non-idiopathic pulmonary fibrosis interstitial lung disease.

Clin Transplant 2019 10 6;33(10):e13661. Epub 2019 Aug 6.

Department of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/ctr.13661DOI Listing
October 2019

Pirfenidone in patients with idiopathic pulmonary fibrosis and more advanced lung function impairment.

Respir Med 2019 07 24;153:44-51. Epub 2019 Apr 24.

Department of Medicine, Cedars-Sinai Medical Center, 87000 Beverly Boulevard, Los Angeles, CA, 90048, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2019.04.016DOI Listing
July 2019

The Ariane-IPF ERS Clinical Research Collaboration: seeking collaboration through launch of a federation of European registries on idiopathic pulmonary fibrosis.

Eur Respir J 2019 05 23;53(5). Epub 2019 May 23.

Reference Centre for Rare Pulmonary Diseases, Université Paris Diderot, Inserm U1152, Laboratoire d'Excellence Inflamex, Assistance Publique-Hôpitaux de Paris, Hôpital Bichat, Service de Pneumologie A, Département Hospitalo-Universitaire FIRE, Paris, France.

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http://dx.doi.org/10.1183/13993003.00539-2019DOI Listing
May 2019

Management of Fibrosing Interstitial Lung Diseases.

Adv Ther 2019 07 22;36(7):1518-1531. Epub 2019 May 22.

Unit for Interstitial Lung Diseases, Department of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1007/s12325-019-00992-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824393PMC
July 2019

Effect of pirfenidone in patients with more advanced idiopathic pulmonary fibrosis.

Respir Res 2019 Mar 12;20(1):55. Epub 2019 Mar 12.

Department of Medicine, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA, 90048, USA.

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http://dx.doi.org/10.1186/s12931-019-1021-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416878PMC
March 2019

Effects of Corticosteroid Treatment and Antigen Avoidance in a Large Hypersensitivity Pneumonitis Cohort: A Single-Centre Cohort Study.

J Clin Med 2018 Dec 21;8(1). Epub 2018 Dec 21.

Department of Respiratory Diseases, Unit for interstitial lung diseases, University Hospitals Leuven, Leuven B-3000, Belgium.

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http://dx.doi.org/10.3390/jcm8010014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352061PMC
December 2018

Idiopathic Pulmonary Fibrosis for Cardiologists: Differential Diagnosis, Cardiovascular Comorbidities, and Patient Management.

Adv Ther 2019 02 15;36(2):298-317. Epub 2018 Dec 15.

U.O. di Pneumologia e Terapia Semi-Intensiva Respiratoria - Servizio di Fisiopatologia Respiratoria ed Emodinamica Polmonare, Ospedale San Giuseppe - MultiMedica IRCCS, Milan, Italy.

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http://dx.doi.org/10.1007/s12325-018-0857-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824347PMC
February 2019

Nintedanib in Idiopathic Pulmonary Fibrosis: Practical Management Recommendations for Potential Adverse Events.

Respiration 2019;97(2):173-184. Epub 2018 Dec 13.

Department of Pulmonary Disease, Erasmus Medical Centre, University Hospital Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1159/000495046DOI Listing
April 2020

Determinants of survival in lung transplantation patients with idiopathic pulmonary fibrosis: a retrospective cohort study.

Transpl Int 2019 04 21;32(4):399-409. Epub 2018 Dec 21.

Department of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/tri.13382DOI Listing
April 2019

Gene correlation network analysis to identify regulatory factors in idiopathic pulmonary fibrosis.

Thorax 2019 02 26;74(2):132-140. Epub 2018 Oct 26.

Laboratory of Respiratory Diseases, Department of Chronic Diseases, Metabolism, and Ageing, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1136/thoraxjnl-2018-211929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467239PMC
February 2019

Short and long-term effects of pulmonary rehabilitation in interstitial lung diseases: a randomised controlled trial.

Respir Res 2018 Sep 20;19(1):182. Epub 2018 Sep 20.

University Hospitals Leuven, Department of Respiratory Diseases, B-3000, Leuven, Belgium.

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http://dx.doi.org/10.1186/s12931-018-0884-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149060PMC
September 2018

Response.

Chest 2018 09;154(3):714-715

Department of Pneumology, Unit for Interstitial Lung Diseases, University Hospitals Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2018.06.020DOI Listing
September 2018

Idiopathic pulmonary fibrosis: time for greater expectations?

Eur Respir J 2018 08 2;52(2). Epub 2018 Aug 2.

Hospices Civils de Lyon, Dept of Respiratory Medicine, National Reference Center for Rare Pulmonary Diseases, Lyon, France.

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http://dx.doi.org/10.1183/13993003.01312-2018DOI Listing
August 2018

Metformin Does Not Affect Clinically Relevant Outcomes in Patients with Idiopathic Pulmonary Fibrosis.

Respiration 2018;96(4):314-322. Epub 2018 Jul 19.

Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1159/000489668DOI Listing
October 2019

Reply to Rajchgot et al.: Combination Nintedanib and Pirfenidone for Treatment of Idiopathic Pulmonary Fibrosis.

Am J Respir Crit Care Med 2018 10;198(8):1105-1106

5 University Hospitals Leuven Leuven, Belgium.

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http://dx.doi.org/10.1164/rccm.201806-1116LEDOI Listing
October 2018

The R178Q mutation is a recurrent cause of hemochromatosis and is associated with a novel pathogenic mechanism.

Haematologica 2018 11 12;103(11):1796-1805. Epub 2018 Jul 12.

UMR1078, INSERM, Université Bretagne Loire - Université de Bretagne Occidentale, Etablissement Français du Sang - Bretagne, Institut Brestois Santé-Agro-Matière, Brest, France

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http://dx.doi.org/10.3324/haematol.2018.189845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278975PMC
November 2018

A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis.

Respir Res 2018 07 9;19(1):132. Epub 2018 Jul 9.

Laboratory of Respiratory Diseases, Department of Chronic Diseases, Metabolism, and Ageing, KU Leuven, Herestraat 49, O&N I, box 706, B-3000, Leuven, Belgium.

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http://dx.doi.org/10.1186/s12931-018-0838-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038197PMC
July 2018

Clinical behaviour of patients exposed to organic dust and diagnosed with idiopathic pulmonary fibrosis.

Respirology 2018 12 13;23(12):1160-1165. Epub 2018 Jun 13.

Laboratory of Pneumology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/resp.13342DOI Listing
December 2018

Role of Targeted Next Generation Sequencing in the Etiological Work-Up of Congenitally Deaf Children.

Otol Neurotol 2018 07;39(6):732-738

Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem.

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http://dx.doi.org/10.1097/MAO.0000000000001847DOI Listing
July 2018

Prevalence of Myositis-Specific Antibodies in Idiopathic Interstitial Pneumonias.

Lung 2018 06 12;196(3):329-333. Epub 2018 Mar 12.

Department of Pneumology, University Hospitals Leuven (UZ Leuven), Herestraat 49, 3000, Louvain, Belgium.

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http://dx.doi.org/10.1007/s00408-018-0108-8DOI Listing
June 2018

Fluxomic assay-assisted diagnosis orientation in a cohort of 11 patients with myopathic form of CPT2 deficiency.

Mol Genet Metab 2018 04 12;123(4):441-448. Epub 2018 Feb 12.

Department of Biochemistry and Molecular Biology, Laboratory of Endocrinology, Metabolism-Nutrition, Oncology, Biology Pathology Center, CHRU Lille, 59037 Lille, France; Univ. Lille, RADEME - Maladies RAres du Développement et du Métabolisme: du phénotype au génotype et à la Fonction, Lille, EA 7364, France; Inserm, Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2018.02.005DOI Listing
April 2018

Unfavourable outcome of glucocorticoid treatment in suspected idiopathic pulmonary fibrosis.

Respirology 2018 03 5;23(3):311-317. Epub 2017 Dec 5.

Interstitial Lung Diseases Center of Excellence, Department of Pulmonology, St Antonius Hospital, Nieuwegein, The Netherlands.

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http://dx.doi.org/10.1111/resp.13230DOI Listing
March 2018

Nintedanib with Add-on Pirfenidone in Idiopathic Pulmonary Fibrosis. Results of the INJOURNEY Trial.

Am J Respir Crit Care Med 2018 02;197(3):356-363

10 Unit for Interstitial Lung Diseases, Department of Respiratory Medicine, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1164/rccm.201706-1301OCDOI Listing
February 2018

Molecular diagnostics for hereditary hearing loss in children.

Expert Rev Mol Diagn 2017 08 19;17(8):751-760. Epub 2017 Jun 19.

a Center of Medical Genetics , University of Antwerp & Antwerp University Hospital , Antwerp , Belgium.

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http://dx.doi.org/10.1080/14737159.2017.1340834DOI Listing
August 2017

Acute exacerbations of interstitial lung disease: lessons from idiopathic pulmonary fibrosis.

Curr Opin Pulm Med 2017 09;23(5):411-417

aSection of Respiratory Diseases, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy bUnit for Interstitial Lung Diseases, Department of Respiratory Medicine, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1097/MCP.0000000000000405DOI Listing
September 2017

Antacid Therapy and Disease Progression in Patients with Idiopathic Pulmonary Fibrosis Who Received Pirfenidone.

Respiration 2017 12;93(6):415-423. Epub 2017 Apr 12.

Center for Interstitial and Rare Lung Diseases, Pneumology and Respiratory Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000468546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452370PMC
March 2018

Targeted Next-Generation Sequencing of 51 Genes Involved in Primary Electrical Disease.

J Mol Diagn 2017 05 22;19(3):445-459. Epub 2017 Mar 22.

Center of Medical Genetics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2017.01.010DOI Listing
May 2017

Connective tissue disease associated interstitial pneumonia: a challenge for both rheumatologists and pulmonologists.

Sarcoidosis Vasc Diffuse Lung Dis 2017 28;34(4):326-335. Epub 2017 Apr 28.

Department of Pneumology, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.36141/svdld.v34i4.5894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170069PMC
April 2017

Trichorhinophalangeal syndrome type II presenting with short stature in a child.

Arch Argent Pediatr 2016 Dec;114(6):e403-e407

Ankara University Faculty of Medicine, Department of Medical Genetics, Ankara, Turkey.

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http://dx.doi.org/10.5546/aap.2016.eng.e403DOI Listing
December 2016

Safety and efficacy of bridging to lung transplantation with antifibrotic drugs in idiopathic pulmonary fibrosis: a case series.

BMC Pulm Med 2016 11 18;16(1):156. Epub 2016 Nov 18.

Department of Respiratory Diseases, Interstitial Lung Disease and Lung Transplant Unit, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1186/s12890-016-0308-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116160PMC
November 2016

Daily Home Spirometry: A New Milestone in the Field of Pulmonary Fibrosis.

Am J Respir Crit Care Med 2016 10;194(8):1033-1034

1 University Hospitals Leuven Leuven, Belgium.

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http://dx.doi.org/10.1164/rccm.201605-1090LEDOI Listing
October 2016

Thin-Section CT Features of Idiopathic Pulmonary Fibrosis Correlated with Micro-CT and Histologic Analysis.

Radiology 2017 04 6;283(1):252-263. Epub 2016 Oct 6.

From the Department of Radiology (C.M., W.D.W., J.C., A.D., J.A.V.), Leuven Lung Transplant Unit (S.E.V., J.E.M., S.W., D.E.V.R., G.M.V., B.M.V., W.A.W.), and Department of Pathology (E.K.V.), UZ Leuven, Herestraat 49, 3000 Leuven, Belgium; and University of British Columbia James Hogg Research Centre, St Paul's Hospital, Vancouver, British Columbia, Canada (J.E.M., J.C.H.).

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http://dx.doi.org/10.1148/radiol.2016152362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375628PMC
April 2017

Sarcoidosis-Like Lesions: Another Paradoxical Reaction to Anti-TNF Therapy?

J Crohns Colitis 2017 Mar;11(3):378-383

Department of Gastroenterology and Hepatology, UZ Leuven, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1093/ecco-jcc/jjw155DOI Listing
March 2017

Gastro-oesophageal reflux and idiopathic pulmonary fibrosis: in search of evidence.

Eur Respir J 2016 09;48(3):623-5

Assistance Publique-Hôpitaux de Paris, Hôpital Bichat, Centre de compétence des maladies pulmonaires rares, INSERM U1152, Université Paris Diderot, LABEX Inflamex, DHU FIRE, Paris, France

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http://dx.doi.org/10.1183/13993003.01444-2016DOI Listing
September 2016

European idiopathic pulmonary fibrosis Patient Charter: a missed opportunity.

Eur Respir J 2016 07;48(1):283-4

Dept of Respiratory Medicine, Unit for ILD, University Hospital Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1183/13993003.00604-2016DOI Listing
July 2016

Novel mutations cause an aggressive atypical neonatal progeria without progerin accumulation.

J Med Genet 2016 Nov 22;53(11):776-785. Epub 2016 Jun 22.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1136/jmedgenet-2015-103695DOI Listing
November 2016

Medical Therapy in Idiopathic Pulmonary Fibrosis.

Semin Respir Crit Care Med 2016 06 27;37(3):368-77. Epub 2016 May 27.

Interstitial Lung Disease Unit, Royal Brompton Hospital, London, United Kingdom.

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http://dx.doi.org/10.1055/s-0036-1582010DOI Listing
June 2016

Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis.

Lancet Respir Med 2016 05 31;4(5):381-9. Epub 2016 Mar 31.

Interstitial and Rare Lung Disease Unit, Ruhrlandklinik, University Hospital, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1016/S2213-2600(16)00067-9DOI Listing
May 2016

An Important Step Forward, but Still a Way to Go.

Am J Respir Crit Care Med 2016 Feb;193(3):340-1

6 Canton Hospital Baselland Basel, Switzerland and.

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http://dx.doi.org/10.1164/rccm.201509-1763LEDOI Listing
February 2016

Gastroesophageal Reflux in Idiopathic Pulmonary Fibrosis: More than a Gut Feeling?

Respiration 2016 5;91(1):1-2. Epub 2016 Jan 5.

Department of Respiratory Medicine, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1159/000443183DOI Listing
August 2016