William Whiteley

William Whiteley

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William Whiteley

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Inspiring New Researchers in Stroke: The ESO Edinburgh Stroke Research Workshop.

Stroke 2019 Oct 15:STROKEAHA119026936. Epub 2019 Oct 15.

Centre for Clinical Brain Sciences, University of Edinburgh (T.J.M., F.D., W.W.).

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http://dx.doi.org/10.1161/STROKEAHA.119.026936DOI Listing
October 2019

A validated natural language processing algorithm for brain imaging phenotypes from radiology reports in UK electronic health records.

BMC Med Inform Decis Mak 2019 Sep 9;19(1):184. Epub 2019 Sep 9.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1186/s12911-019-0908-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734359PMC
September 2019

CNN-based PET sinogram repair to mitigate defective block detectors.

Phys Med Biol 2019 Sep 30. Epub 2019 Sep 30.

Electrical Engineering and Computer Science, University of Tennessee, Knoxville, Tennessee, UNITED STATES.

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http://dx.doi.org/10.1088/1361-6560/ab4919DOI Listing
September 2019

Intensive Blood Pressure Lowering in Patients With Renal Impairment and Lacunar Stroke.

J Am Heart Assoc 2019 Aug 19;8(16):e013637. Epub 2019 Aug 19.

Centre for Clinical Brain Sciences University of Edinburgh United Kingdom.

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http://dx.doi.org/10.1161/JAHA.119.013637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759888PMC
August 2019

Reproducibility of Transcranial Doppler ultrasound in the middle cerebral artery.

Cardiovasc Ultrasound 2018 Sep 11;16(1):15. Epub 2018 Sep 11.

British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SA, UK.

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http://dx.doi.org/10.1186/s12947-018-0133-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131943PMC
September 2018

Treating anxiety after stroke (TASK): the feasibility phase of a novel web-enabled randomised controlled trial.

Pilot Feasibility Stud 2018 14;4:139. Epub 2018 Aug 14.

Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, Midlothian, EH16 4SB UK.

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http://dx.doi.org/10.1186/s40814-018-0329-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092858PMC
August 2018

Anxiety After Stroke: The Importance of Subtyping.

Stroke 2018 03 6;49(3):556-564. Epub 2018 Feb 6.

From the Stroke Research Group, Centre for Clinical Brain Sciences, University of Edinburgh, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.117.020078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839706PMC
March 2018

How to do high-quality clinical research 1: First steps.

Int J Stroke 2018 02 4;13(2):121-128. Epub 2018 Jan 4.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1177/1747493017750923DOI Listing
February 2018

Routinely collected data for randomized trials: promises, barriers, and implications.

Trials 2018 Jan 11;19(1):29. Epub 2018 Jan 11.

Basel Institute for Clinical Epidemiology and Biostatistics (CEB), Department of Clinical Research, University Hospital Basel, University of Basel, Spitalstrasse 12, 4031, Basel, Switzerland.

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http://dx.doi.org/10.1186/s13063-017-2394-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765645PMC
January 2018

Shared decision making after severe stroke-How can we improve patient and family involvement in treatment decisions?

Int J Stroke 2017 12 12;12(9):920-922. Epub 2017 Sep 12.

1 Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://journals.sagepub.com/doi/full/10.1177/174749301773074
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http://dx.doi.org/10.1177/1747493017730746DOI Listing
December 2017

Anticoagulation Timing for Atrial Fibrillation in Acute Ischemic Stroke: Time to Reopen Pandora's Box?

JAMA Neurol 2017 10;74(10):1174-1175

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, Scotland.

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http://dx.doi.org/10.1001/jamaneurol.2017.1919DOI Listing
October 2017

F-Fluoride and F-Fluorodeoxyglucose Positron Emission Tomography After Transient Ischemic Attack or Minor Ischemic Stroke: Case-Control Study.

Circ Cardiovasc Imaging 2017 Mar;10(3)

From the BHF Centre for Cardiovascular Science, University of Edinburgh, United Kingdom (A.T.V., W.S.A.J., A.M., G.S., R.O.F., N.L.M., E.J.R.v.B., M.R.D., D.E.N.); Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, United Kingdom (A.I., J.R., A.P.D.); and Clinical Research Imaging Centre (T.C., G.R., A.F., C.L., E.J.R.v.B., M.R.D., D.E.N.) and Centre for Clinical Brain Sciences (R.A.-S.S., M.D., W.W.), University of Edinburgh, United Kingdom.

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http://dx.doi.org/10.1161/CIRCIMAGING.116.004976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367506PMC
March 2017

Mortality after thrombolysis - Authors' reply.

Lancet Neurol 2016 12;15(13):1305

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/S1474-4422(16)30280-0DOI Listing
December 2016

Cognition in chronic kidney disease: a systematic review and meta-analysis.

BMC Med 2016 Dec 14;14(1):206. Epub 2016 Dec 14.

Sydney School of Public Health, Sydney Medical School, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1186/s12916-016-0745-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155375PMC
December 2016

Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes: A Pooled Analysis of 9 Trials.

Stroke 2016 09 9;47(9):2373-9. Epub 2016 Aug 9.

From the Institute of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom (K.R.L.); Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, United Kingdom (J.E., L.B., C.B.); Statistics Department, Boehringer Ingelheim, Germany (E.B.); Melbourne Brain Centre, The Royal Melbourne Hospital and University of Melbourne, Australia (S.M.D.); Stroke Division, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Australia (G.A.D.); Mobile Stroke Unit and Stroke Research Program, Memorial Hermann Hospital, Houston, TX (J.C.G.); Department of Neurology, Helsinki University Hospital and Clinical Neurosciences, University of Helsinki, Finland (M.K.); Department of Neuroradiology, Technische Universität, Dresden, Germany (R.v.K.); Stanford Stroke Center, Palo Alto, CA (M.G.L.); Discipline of Medicine, Westmead Hospital Clinical School, George Institute for Global Health, University of Sydney, NSW, Australia (R.I.L.); Department of Neurology, Cedars-Sinai, Los Angeles, CA (P.L.); Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, United Kingdom (G.D.M.); Centre for Clinical Brain Sciences, University of Edinburgh, United Kingdom (P.A.G.S., J.M.W., W.N.W.); Department of Neurology and Psychiatry, Sapienza University of Rome, Italy (D.T.); Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.T.); Department of Neurology, University of Heidelberg, Im Neuenheimer Feld, Germany (W.H.); and Department of Biostatistics, UAB School of Public Health, Birmingham, AL (G.H.).

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http://dx.doi.org/10.1161/STROKEAHA.116.013644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024752PMC
September 2016

Cognition in People With End-Stage Kidney Disease Treated With Hemodialysis: A Systematic Review and Meta-analysis.

Am J Kidney Dis 2016 Jun 23;67(6):925-35. Epub 2016 Feb 23.

Sydney School of Public Health, Sydney Medical School, University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia; Centre for Transplant and Renal Research, Westmead Millennium Institute, University of Sydney at Westmead, Sydney, Australia.

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http://dx.doi.org/10.1053/j.ajkd.2015.12.028DOI Listing
June 2016

IST-3 stroke trial data available.

Lancet 2016 May;387(10031):1904

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, UK.

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http://dx.doi.org/10.1016/S0140-6736(16)30414-7DOI Listing
May 2016

Effects of Blood Pressure and Blood Pressure-Lowering Treatment During the First 24 Hours Among Patients in the Third International Stroke Trial of Thrombolytic Treatment for Acute Ischemic Stroke.

Stroke 2015 Dec 20;46(12):3362-9. Epub 2015 Oct 20.

From the Departments of Internal Medicine (E.B.) and Neurology (E.C.S.), Oslo University Hospital, Oslo, Norway; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, Scotland (G.C., P.S., J.M.W., W.W.); and George Institute for Global Health and Discipline of Medicine, University of Sydney, Sydney, New South Wales, Australia (R.I.L.).

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http://dx.doi.org/10.1161/STROKEAHA.115.010319DOI Listing
December 2015

Targeting aspirin in acute disabling ischemic stroke: an individual patient data meta-analysis of three large randomized trials.

Int J Stroke 2015 Oct 12;10(7):1024-30. Epub 2015 Apr 12.

Edinburgh MRC Hub for Trials Methodology Research, Centre for Population Health Sciences, University of Edinburgh Medical School, Edinburgh, UK.

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http://dx.doi.org/10.1111/ijs.12487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973666PMC
October 2015

The Heidelberg Bleeding Classification: Classification of Bleeding Events After Ischemic Stroke and Reperfusion Therapy.

Stroke 2015 Oct 1;46(10):2981-6. Epub 2015 Sep 1.

From the Institut und Poliklinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum Carl Gustav Carus, Dresden, Germany (R.v.K.); Departments of Neurology and Rehabilitation Medicine and Radiology, University of Cincinnati, OH (J.P.B.); Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia (B.C.V.C.); Department of Radiology and Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada (A.D., M.G., M.D.H.); Department of Radiology (K.M.T., C.B.L.M.M.) and Department of Biomedical Engineering and Physics, Academic Medical Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands (H.A.M.); Department of Neurology, Karolinska University Hospital and Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden (M.V.M.); Department of Radiology, Hospital Clínic, Barcelona, Spain (L.S.R.); Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine; Los Angeles, CA (J.L.S.); Department of Neurology, Helsinki University Central Hospital and Department of Neurological Sciences, University of Helsinki, Helsinki, Finland (D.S.); University of Edinburgh, Edinburgh, United Kingdom (W.W.); and Department of Neurology, University of Heidelberg, Heidelberg, Germany (W.H.).

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http://dx.doi.org/10.1161/STROKEAHA.115.010049DOI Listing
October 2015

Covariate adjustment had similar benefits in small and large randomized controlled trials.

J Clin Epidemiol 2015 Sep 13;68(9):1068-75. Epub 2014 Nov 13.

Department of Public Health, Centre for Medical Decision Sciences, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jclinepi.2014.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708297PMC
September 2015

Parenteral fluid regimens for improving functional outcome in people with acute stroke.

Cochrane Database Syst Rev 2015 Sep 1(9):CD011138. Epub 2015 Sep 1.

Medicine of the Elderly, NHS Lothian, Royal Victoria Building, Western General Hospital, Edinburgh, UK, EH4 2XU.

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http://dx.doi.org/10.1002/14651858.CD011138.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464870PMC
September 2015

Functional status three months after the first ischemic stroke is associated with long-term outcome: data from a community-based cohort.

Cerebrovasc Dis 2014 16;38(1):46-54. Epub 2014 Sep 16.

Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1159/000364938DOI Listing
July 2015

Anxiety after stroke: time for an intervention.

Int J Stroke 2015 Jul;10(5):655-6

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/ijs.12493DOI Listing
July 2015

Alteplase for acute ischemic stroke: outcomes by clinically important subgroups in the Third International Stroke Trial.

Stroke 2015 Mar 22;46(3):746-56. Epub 2015 Jan 22.

From the University of Sydney, Sydney, Australia (R.I.L.); University of Edinburgh, Edinburgh, UK (J.M.W., W.N.W., G.C., G.D.M., P.A.G.S.); and University of Oxford, Oxford, UK (L.B.).

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http://dx.doi.org/10.1161/STROKEAHA.114.006573DOI Listing
March 2015

Short term exposure to air pollution and stroke: systematic review and meta-analysis.

BMJ 2015 Mar 24;350:h1295. Epub 2015 Mar 24.

BHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4SB, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373601PMC
http://dx.doi.org/10.1136/bmj.h1295DOI Listing
March 2015

Effect of alteplase within 6 hours of acute ischemic stroke on all-cause mortality (third International Stroke Trial).

Stroke 2014 Dec 4;45(12):3612-7. Epub 2014 Nov 4.

From the Centre for Clinical Brain Sciences (W.N.W., G.C., J.W., P.S.) and Centre for Population Health Sciences (D.T., G.M.), University of Edinburgh, United Kingdom; Neurological & Mental Health Division, George Institute for Global Health, University of Sydney, Australia (R.I.L.); and Neuroimaging Sciences, Edinburgh, United Kingdom (J.W.).

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http://dx.doi.org/10.1161/STROKEAHA.114.006890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282176PMC
December 2014

Targeting recombinant tissue-type plasminogen activator in acute ischemic stroke based on risk of intracranial hemorrhage or poor functional outcome: an analysis of the third international stroke trial.

Stroke 2014 Apr 6;45(4):1000-6. Epub 2014 Mar 6.

From the Divisions of Clinical Neurosciences (W.N.W., G.C., P.S.) and Neuroimaging Sciences (J.W.), University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom; Edinburgh MRC Hub for Trials Methodology Research, Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom (D.T., G.M.); and Neurological and Mental Health Division, The George Institute for Global Health, University of Sydney, Sydney, Australia (R.I.L.).

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http://stroke.ahajournals.org/content/45/4/1000.full.pdf
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http://stroke.ahajournals.org/cgi/doi/10.1161/STROKEAHA.113.
Publisher Site
http://dx.doi.org/10.1161/STROKEAHA.113.004362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282175PMC
April 2014

Formal and informal prediction of recurrent stroke and myocardial infarction after stroke: a systematic review and evaluation of clinical prediction models in a new cohort.

BMC Med 2014 Apr 4;12:58. Epub 2014 Apr 4.

Edinburgh MRC Hub for Trials Methodology Research, Centre for Population Health Sciences, University of Edinburgh Medical School, Teviot Place, Edinburgh EH8 9AG, UK.

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http://dx.doi.org/10.1186/1741-7015-12-58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022243PMC
April 2014

B-type natriuretic peptides and mortality after stroke: a systematic review and meta-analysis.

Neurology 2013 Dec 1;81(23):1976-85. Epub 2013 Nov 1.

From the Neurovascular Research Laboratory (T.G.-B., D.G., A.B., J.M.), Vall d'Hebron Institute of Research, Universitat Autònoma de Barcelona, Spain; Department of Neurology (T.E.), Kliniken Südostbayern-Klinikum Traunstein, Germany; Department of Psychiatry and Psychotherapy (T.E.), Technische Universität München, Germany; Department of Cardiology (J.K.J.), Odense University, Denmark; Stroke Medicine (J.C.S.), Lincoln County Hospital, University of Nottingham, UK; Department of Stroke Medicine (K.S.), Kawasaki Medical School, Kurashiki City, Okayama, Japan; Department of Emergency Medicine (A.S.), School of Medicine, Duzce University, Turkey; Department of Neurology (X.C.), Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China; and Centre for Clinical Brain Sciences (W.N.W.), University of Edinburgh, UK.

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http://www.neurology.org/cgi/doi/10.1212/01.wnl.0000436937.3
Publisher Site
http://dx.doi.org/10.1212/01.wnl.0000436937.32410.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854833PMC
December 2013

Strokes: mimics and chameleons.

Pract Neurol 2013 Feb;13(1):21-8

Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1136/practneurol-2012-000465DOI Listing
February 2013

Blood biomarkers in stroke: research and clinical practice.

Int J Stroke 2012 Jul 30;7(5):435-9. Epub 2012 Mar 30.

Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/j.1747-4949.2012.00784.xDOI Listing
July 2012

Correlation of levels of neuronal and glial markers with radiological measures of infarct volume in ischaemic stroke: a systematic review.

Cerebrovasc Dis 2012 1;33(1):47-54. Epub 2011 Dec 1.

Division of Clinical Neurosciences, Bramwell Dott Building, Western General Hospital, Edinburgh, UK.

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https://www.karger.com/Article/FullText/332810
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http://dx.doi.org/10.1159/000332810DOI Listing
May 2012

Blood biomarkers for the diagnosis of acute cerebrovascular diseases: a prospective cohort study.

Cerebrovasc Dis 2011 19;32(2):141-7. Epub 2011 Jul 19.

Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh, UK. william.whiteley @ ed.ac.uk

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http://dx.doi.org/10.1159/000328517DOI Listing
January 2012

The use of blood biomarkers to predict poor outcome after acute transient ischemic attack or ischemic stroke.

Stroke 2012 Jan 20;43(1):86-91. Epub 2011 Oct 20.

Division of Clinical Neurosciences, General Hospital, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1161/STROKEAHA.111.634089DOI Listing
January 2012

Hoover's sign for the diagnosis of functional weakness: a prospective unblinded cohort study in patients with suspected stroke.

J Psychosom Res 2011 Dec 6;71(6):384-6. Epub 2011 Oct 6.

Division of Clinical Neurosciences, Bramwell Dott Building, Western General Hospital, Edinburgh EH4 2XU, United Kingdom.

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http://dx.doi.org/10.1016/j.jpsychores.2011.09.003DOI Listing
December 2011

Clinical scores for the identification of stroke and transient ischaemic attack in the emergency department: a cross-sectional study.

J Neurol Neurosurg Psychiatry 2011 Sep 14;82(9):1006-10. Epub 2011 Mar 14.

Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

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http://jnnp.bmj.com/cgi/doi/10.1136/jnnp.2010.235010
Publisher Site
http://dx.doi.org/10.1136/jnnp.2010.235010DOI Listing
September 2011

Inflammatory markers and poor outcome after stroke: a prospective cohort study and systematic review of interleukin-6.

PLoS Med 2009 Sep 8;6(9):e1000145. Epub 2009 Sep 8.

Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1000145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730573PMC
September 2009

Blood markers for the prognosis of ischemic stroke: a systematic review.

Stroke 2009 May 12;40(5):e380-9. Epub 2009 Mar 12.

Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1161/STROKEAHA.108.528752DOI Listing
May 2009

Blood biomarkers in the diagnosis of ischemic stroke: a systematic review.

Stroke 2008 Oct 24;39(10):2902-9. Epub 2008 Jul 24.

Division of Clinical Neurosciences, University of Edinburgh, UK.

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http://dx.doi.org/10.1161/STROKEAHA.107.511261DOI Listing
October 2008

Ward round: A patient with blurred vision and leg weakness.

Malawi Med J 2007 Jun;19(2):87-93

Registrar in Medicine ; Professor of Medicine ; Department of Medicine, College of Medicine, Private Bag 360, Chichiri, Blantyre, Malawi.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345640PMC
June 2007

Screening using whole-body magnetic resonance imaging scanning: who wants an incidentaloma?

J Med Screen 2007 ;14(1):2-4

Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1258/096914107780154530DOI Listing
May 2007

Cerebral aneurysms.

N Engl J Med 2006 Dec;355(25):2704-5; author reply 2705

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December 2006

Fridtjof Nansen (1861-1930).

Authors:
William Whiteley

J Neurol 2006 Dec;253(12):1653-4

Department of Clinical Neurosciences, Western General Hospital, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1007/s00415-006-0418-2DOI Listing
December 2006

Third international stroke trial.

Int J Stroke 2006 Aug;1(3):172-6

Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1111/j.1747-4949.2006.00043.xDOI Listing
August 2006