William U Shipley

William U Shipley

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William U Shipley

William U Shipley

Publications by authors named "William U Shipley"

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Comparative Effectiveness of Bladder-preserving Tri-modality Therapy Versus Radical Cystectomy for Muscle-invasive Bladder Cancer.

Clin Genitourin Cancer 2019 Feb 4;17(1):23-31.e3. Epub 2018 Oct 4.

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2018.09.023DOI Listing
February 2019

Molecular biomarkers in bladder preservation therapy for muscle-invasive bladder cancer.

Lancet Oncol 2018 12;19(12):e683-e695

Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(18)30693-4DOI Listing
December 2018

Clinical characteristics and outcomes of nonurothelial cell carcinoma of the bladder: Results from the National Cancer Data Base.

Urol Oncol 2018 02 20;36(2):78.e1-78.e12. Epub 2017 Nov 20.

Department of Radiation Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2017.10.013DOI Listing
February 2018

Less Is More.

Int J Radiat Oncol Biol Phys 2017 09 7;99(1):7-8. Epub 2017 Aug 7.

Department of Radiation Oncology, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.ijrobp.2017.04.012DOI Listing
September 2017

Radiation with or without Antiandrogen Therapy in Recurrent Prostate Cancer.

N Engl J Med 2017 02;376(5):417-428

From Massachusetts General Hospital and Harvard Medical School, Boston (W.U.S., N.M.H., A.L.Z.); NRG Oncology Statistics and Data Management Center (W.S., J.J.D., S.L.P.) and Einstein Medical Center (K.L.Z.), Philadelphia; Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, ON (H.R.L., P.P.M., M.P.P.), Hospital Notre-Dame du Centre Hospitalier de l'Université de Montréal (J.-P.B.) and McGill University Health Centre (L.S.), Montreal, and Tom Baker Cancer Centre, Calgary, AB (A.G.B.) - all in Canada; Indiana University, Indianapolis (D.J.G.); Tulane University, New Orleans (O.S.); Mayo Clinic, Rochester, MN (T.M.P.); Medical College of Wisconsin, Milwaukee (C.A.F.L.); University of Michigan, Ann Arbor (F.Y.F.); University of Vermont Medical Center, Burlington (R.D.L.); Radiation Oncology Center, Sacramento (S.A.R.), and Cedars-Sinai Medical Center, Los Angeles (H.M.S.) - both in California; Wayne Radiation Oncology, Goldsboro, NC (K.J.K.); and the University of Chicago, Chicago (J.J.D.).

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http://dx.doi.org/10.1056/NEJMoa1607529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444881PMC
February 2017

Quality of Life in Long-term Survivors of Muscle-Invasive Bladder Cancer.

Int J Radiat Oncol Biol Phys 2016 12 24;96(5):1028-1036. Epub 2016 Aug 24.

Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2016.08.023DOI Listing
December 2016

Words of Wisdom. Re: Radical Cystectomy vs. Chemoradiation in T2-4aN0M0 Bladder Cancer: A Case-control Study.

Eur Urol 2016 Apr 18;69(4):757-8. Epub 2016 Feb 18.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.eururo.2016.01.022DOI Listing
April 2016

Bladder preservation strategies.

Hematol Oncol Clin North Am 2015 Apr 15;29(2):289-300, ix. Epub 2014 Dec 15.

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, 100 Blossom Street, Cox 3, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.hoc.2014.10.004DOI Listing
April 2015

Duration of androgen suppression before radiotherapy for localized prostate cancer: radiation therapy oncology group randomized clinical trial 9910.

J Clin Oncol 2015 Feb 22;33(4):332-9. Epub 2014 Dec 22.

Thomas M. Pisansky, Mayo Clinic, Rochester, MN; Daniel Hunt and James J. Dignam, Radiation Therapy Oncology Group Statistical Center; Leonard G. Gomella, Thomas Jefferson University, Philadelphia, PA; Mahul B. Amin and Howard M. Sandler, Cedars-Sinai Medical Center, Los Angeles; Daniel M. Chinn, John Muir Medical Center-Concord Campus, Concord; Seth A. Rosenthal, Sutter Medical Group, Sacramento, CA; Michael J. Seider, Akron City Hospital, Akron, OH; Elizabeth M. Gore, Zablocki Veterans Administration Medical Center-Wood, Milwaukee, WI; Marvin Z. Rotman, Brooklyn Minority-Based Community Clinical Oncology Program, State University of New York Downstate, Brooklyn, NY; William U. Shipley, Massachusetts General Hospital, Boston, MA; James J. Dignam, University of Chicago, Chicago, IL; Alexander G. Balogh, Tom Baker Cancer Centre, Calgary, Alberta; Marie Duclos, McGill University, Montreal, Quebec; Glenn S. Bauman, London Regional Cancer Program, London; and Himanshu R. Lukka, McMaster University, Hamilton, Ontario, Canada.

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http://jco.ascopubs.org/content/early/2014/12/22/JCO.2014.58
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.58.0662
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http://dx.doi.org/10.1200/JCO.2014.58.0662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302214PMC
February 2015

Long-term outcomes in patients with muscle-invasive bladder cancer after selective bladder-preserving combined-modality therapy: a pooled analysis of Radiation Therapy Oncology Group protocols 8802, 8903, 9506, 9706, 9906, and 0233.

J Clin Oncol 2014 Dec 3;32(34):3801-9. Epub 2014 Nov 3.

Raymond H. Mak, Brigham and Women's Hospital/Dana-Farber Cancer Institute and Harvard Medical School; William U. Shipley, Jason A. Efstathiou, Donald S. Kaufman, Niall M. Heney, and Anthony L. Zietman, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Daniel Hunt, Radiation Therapy Oncology Group Statistical Center; William J. Tester, Albert Einstein Medical Center, Philadelphia, PA; and Michael P. Hagan, Veterans Health Administration, Richmond, VA.

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http://ascopubs.org/doi/10.1200/JCO.2014.57.5548
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http://dx.doi.org/10.1200/JCO.2014.57.5548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239302PMC
December 2014

Critical analysis of bladder sparing with trimodal therapy in muscle-invasive bladder cancer: a systematic review.

Eur Urol 2014 Jul 26;66(1):120-37. Epub 2014 Feb 26.

Department of Surgery, Division of Urology, McGill University, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2014.02.038DOI Listing
July 2014

Recent advances and the emerging role for chemoradiation in nonmuscle invasive bladder cancer.

Curr Opin Urol 2013 Sep;23(5):429-34

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1097/MOU.0b013e328363de04DOI Listing
September 2013

T1 high-grade bladder cancer recurring after BCG therapy: a curative alternative to radical cystectomy exists. Con.

Oncology (Williston Park) 2013 Sep;27(9):873, 921

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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September 2013

Trimodality bladder preservation therapy for muscle-invasive bladder cancer.

J Natl Compr Canc Netw 2013 Aug;11(8):952-60

From the aDepartment of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, and bDepartment of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.6004/jnccn.2013.0116DOI Listing
August 2013

Nomograms predicting response to therapy and outcomes after bladder-preserving trimodality therapy for muscle-invasive bladder cancer.

Int J Radiat Oncol Biol Phys 2013 Jun 6;86(2):311-6. Epub 2013 Mar 6.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2013.01.020DOI Listing
June 2013

Use of potentially curative therapies for muscle-invasive bladder cancer in the United States: results from the National Cancer Data Base.

Eur Urol 2013 May 19;63(5):823-9. Epub 2012 Nov 19.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.eururo.2012.11.015DOI Listing
May 2013

The opportunity cost of androgen suppression in locally advanced prostate cancer.

Asian J Androl 2013 May 25;15(3):356-7. Epub 2013 Feb 25.

Harvard Radiation Oncology Program, Boston, MA 02114, USA.

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http://dx.doi.org/10.1038/aja.2012.166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739662PMC
May 2013

Trimodality therapy for bladder conservation in treatment of invasive bladder cancer.

Curr Urol Rep 2013 Apr;14(2):109-15

Harvard Medical School, Massachusetts General Hospital, Department of Radiation Oncology, Boston, MA 02114, USA.

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http://dx.doi.org/10.1007/s11934-012-0301-xDOI Listing
April 2013

Words of wisdom. Re: Radiotherapy with or without chemotherapy in muscle-invasive bladder cancer.

Eur Urol 2013 Jan;63(1):181-2

Department of Radiation Oncology, Massachusetts General Hospital, Boston, USA.

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http://dx.doi.org/10.1016/j.eururo.2012.10.032DOI Listing
January 2013

Urological cancer. The benefits of intermittent androgen-deprivation therapy.

Nat Rev Clin Oncol 2012 Dec 20;9(12):672-3. Epub 2012 Nov 20.

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1038/nrclinonc.2012.201DOI Listing
December 2012

The importance of combined radiation and endocrine therapy in locally advanced prostate cancer.

Asian J Androl 2012 Mar 26;14(2):245-6. Epub 2011 Dec 26.

Harvard Radiation Oncology Program, Boston, MA 02114, USA.

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http://dx.doi.org/10.1038/aja.2011.177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735089PMC
March 2012

Long-term quality of life outcome after proton beam monotherapy for localized prostate cancer.

Int J Radiat Oncol Biol Phys 2012 Feb 27;82(2):e201-9. Epub 2011 May 27.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2011.03.048DOI Listing
February 2012

Comparison of high-dose proton radiotherapy and brachytherapy in localized prostate cancer: a case-matched analysis.

Int J Radiat Oncol Biol Phys 2012 Jan 4;82(1):e25-31. Epub 2011 Apr 4.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2011.01.039DOI Listing
January 2012

Acute and late toxicity after dose escalation to 82 GyE using conformal proton radiation for localized prostate cancer: initial report of American College of Radiology Phase II study 03-12.

Int J Radiat Oncol Biol Phys 2011 Nov 6;81(4):1005-9. Epub 2010 Oct 6.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2010.06.047DOI Listing
November 2011

Rectal dose-volume histogram parameters are associated with long-term patient-reported gastrointestinal quality of life after conventional and high-dose radiation for prostate cancer: a subgroup analysis of a randomized trial.

Int J Radiat Oncol Biol Phys 2010 Nov 6;78(4):1081-5. Epub 2010 Mar 6.

Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2009.09.015DOI Listing
November 2010

Survivin is a potential mediator of prostate cancer metastasis.

Int J Radiat Oncol Biol Phys 2010 Nov 16;78(4):1095-103. Epub 2010 Mar 16.

Arthur G. James Comprehensive Cancer Center, The Ohio State University Medical School, Columbus, OH 43210, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S03603016090310
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http://dx.doi.org/10.1016/j.ijrobp.2009.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348096PMC
November 2010

Radiation dose-volume effects of the urinary bladder.

Int J Radiat Oncol Biol Phys 2010 Mar;76(3 Suppl):S116-22

Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2009.02.090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587780PMC
March 2010

Patient-reported long-term outcomes after conventional and high-dose combined proton and photon radiation for early prostate cancer.

JAMA 2010 Mar;303(11):1046-53

Center for Outcomes Research, MGH Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1001/jama.2010.287DOI Listing
March 2010

Late pelvic toxicity after bladder-sparing therapy in patients with invasive bladder cancer: RTOG 89-03, 95-06, 97-06, 99-06.

J Clin Oncol 2009 Sep 27;27(25):4055-61. Epub 2009 Jul 27.

Department of Radiation Oncology, Massachusetts General Hospital, 100 Blossom St, Cox 3, Boston, MA 02114, USA.

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http://dx.doi.org/10.1200/JCO.2008.19.5776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734419PMC
September 2009

Bladder cancer.

Lancet 2009 Jul 10;374(9685):239-49. Epub 2009 Jun 10.

Department of Medicine, the Claire and John Bertucci Center for Genitourinary Cancers, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/S0140-6736(09)60491-8DOI Listing
July 2009

Surgery: selective bladder-preserving therapy for muscle-invasive cancer.

Nat Rev Clin Oncol 2009 04;6(4):193-4

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 0211, USA.

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http://dx.doi.org/10.1038/nrclinonc.2009.21DOI Listing
April 2009

Potential surrogate endpoints for prostate cancer survival: analysis of a phase III randomized trial.

J Natl Cancer Inst 2009 Feb 10;101(4):228-36. Epub 2009 Feb 10.

Radiology Associates of Appleton, Appleton, WI 54911, USA.

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http://dx.doi.org/10.1093/jnci/djn489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734115PMC
February 2009

Cardiovascular mortality after androgen deprivation therapy for locally advanced prostate cancer: RTOG 85-31.

J Clin Oncol 2009 Jan 1;27(1):92-9. Epub 2008 Dec 1.

Department of Radiation Oncology and Division of Hematology and Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1200/JCO.2007.12.3752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645096PMC
January 2009

Does timing of androgen deprivation influence radiation-induced toxicity? A secondary analysis of radiation therapy oncology group protocol 9413.

Urology 2008 Nov 7;72(5):1125-9. Epub 2008 Mar 7.

Department of Radiation Oncology, Montreal University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.urology.2007.11.067DOI Listing
November 2008

Bladder preservation: optimizing radiotherapy and integrated treatment strategies.

BJU Int 2008 Nov;102(9 Pt B):1345-53

Department of Radiation, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1111/j.1464-410X.2008.07981.xDOI Listing
November 2008

Cardiovascular mortality and duration of androgen deprivation for locally advanced prostate cancer: analysis of RTOG 92-02.

Eur Urol 2008 Oct 15;54(4):816-23. Epub 2008 Jan 15.

Department of Radiation Oncology, Massachusetts General Hospital, 100 Blossom Street, Boston, MA 02114, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S030228380800022
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http://dx.doi.org/10.1016/j.eururo.2008.01.021DOI Listing
October 2008

Diabetes and mortality in men with locally advanced prostate cancer: RTOG 92-02.

J Clin Oncol 2008 Sep;26(26):4333-9

Department of Radiation Oncology, Division of Hematology and Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1200/JCO.2008.16.5845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653118PMC
September 2008

Newer imaging modalities to assist with target localization in the radiation treatment of prostate cancer and possible lymph node metastases.

Int J Radiat Oncol Biol Phys 2008 ;71(1 Suppl):S43-7

Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2007.06.079DOI Listing
June 2008

Obesity and mortality in men with locally advanced prostate cancer: analysis of RTOG 85-31.

Cancer 2007 Dec;110(12):2691-9

Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1002/cncr.23093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047389PMC
December 2007

Radiotherapy treatment of early-stage prostate cancer with IMRT and protons: a treatment planning comparison.

Int J Radiat Oncol Biol Phys 2007 Oct 21;69(2):444-53. Epub 2007 May 21.

Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2007.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695934PMC
October 2007

Benchmarks achieved in the delivery of radiation therapy for muscle-invasive bladder cancer.

Urol Oncol 2007 Jan-Feb;25(1):76-84

Department of Radiation Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.urolonc.2006.05.012DOI Listing
February 2007

Radiation-sensitizing chemotherapy after transurethral resection as an alternative treatment for high-risk T1 bladder cancer.

Nat Clin Pract Urol 2007 Jan;4(1):24-5

Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/ncpuro0675DOI Listing
January 2007

Association of statin use with improved local control in patients treated with selective bladder preservation for muscle-invasive bladder cancer.

Urology 2006 Dec 4;68(6):1188-92. Epub 2006 Dec 4.

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1016/j.urology.2006.08.1078DOI Listing
December 2006

Bladder-sparing approaches to invasive disease.

World J Urol 2006 Nov;24(5):517-29

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, 100 Blossom Street, Cox 3, Boston, MA 02114, USA.

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http://dx.doi.org/10.1007/s00345-006-0114-yDOI Listing
November 2006

Increasing external beam dose for T1-T2 prostate cancer: effect on risk groups.

Int J Radiat Oncol Biol Phys 2006 Jul 5;65(4):975-81. Epub 2006 Jun 5.

Department of Biostatistics and Applied Mathematics, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, and Department of Radiation Oncology, William Beaumont Hospital, Deroit, MI, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2006.02.043DOI Listing
July 2006

Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: recommendations of the RTOG-ASTRO Phoenix Consensus Conference.

Int J Radiat Oncol Biol Phys 2006 Jul;65(4):965-74

Department of Radiation Oncology, University of California San Francisco, San Francisco, CA 94143-1708, and Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S036030160600663
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http://dx.doi.org/10.1016/j.ijrobp.2006.04.029DOI Listing
July 2006