William Singer

William Singer

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William Singer

William Singer

Publications by authors named "William Singer"

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25Publications

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Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors.

Bioorg Med Chem 2017 02 7;25(4):1320-1328. Epub 2016 Dec 7.

Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.11.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484535PMC
February 2017

Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine.

J Biol Chem 2017 Jan 21;292(1):112-120. Epub 2016 Nov 21.

From the Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 and

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http://dx.doi.org/10.1074/jbc.M116.750299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217671PMC
January 2017

Increased dietary cholesterol promotes enhanced mutagenesis in DNA polymerase kappa-deficient mice.

DNA Repair (Amst) 2013 Oct 13;12(10):817-23. Epub 2013 Aug 13.

Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9072, United States.

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http://dx.doi.org/10.1016/j.dnarep.2013.07.010DOI Listing
October 2013

Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF.

Structure 2008 Oct;16(10):1532-43

Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S096921260800299
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http://dx.doi.org/10.1016/j.str.2008.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586972PMC
October 2008

Regulation of Rho guanine nucleotide exchange factors by G proteins.

Adv Protein Chem 2007 ;74:189-228

Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1016/S0065-3233(07)74006-8DOI Listing
June 2008

Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.

Nat Struct Mol Biol 2005 Feb 16;12(2):191-7. Epub 2005 Jan 16.

Department of Biochemistry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1038/nsmb888DOI Listing
February 2005

Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF.

J Biol Chem 2003 Mar 13;278(11):9912-9. Epub 2003 Jan 13.

Department of Biochemistry, the University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1074/jbc.M212695200DOI Listing
March 2003

Brown tumors of the skull base. Case report and review of the literature.

J Neurosurg 2003 Feb;98(2):417-20

Department of Neurosurgery, St. Michael's Hospital and University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.3171/jns.2003.98.2.0417DOI Listing
February 2003

Assays and characterization of mammalian phosphatidylinositol 4,5-bisphosphate-sensitive phospholipase D.

Methods Enzymol 2002 ;345:328-34

Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)45026-4DOI Listing
April 2002

The effect of somatostatin on growth hormone synthesis or release.

Authors:
Singer William

Endocr Pathol 1990 Dec;1(4):196

Associate Professor of Medicine and Clinical Biochemistry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/BF02915413DOI Listing
December 1990

The adrenal cortex in ectopic adrenocorticotropic hormone syndrome: A morphological study with histology, transmission and scanning electron microscopy, flow cytometry, and image analysis.

Endocr Pathol 1990 Sep;1(3):183-191

Departments of Pathology and Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/BF02915393DOI Listing
September 1990