Publications by authors named "William S James"

20Publications

Honing the Double-Edged Sword: Improving Human iPSC-Microglia Models.

Front Immunol 2020 8;11:614972. Epub 2020 Dec 8.

Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.

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December 2020

Interferon-stimulated gene products as regulators of central carbon metabolism.

FEBS J 2020 Nov 13. Epub 2020 Nov 13.

Chemistry Research Laboratory, Department of Chemistry, University of Oxford, UK.

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November 2020

LRRK2 Is Recruited to Phagosomes and Co-recruits RAB8 and RAB10 in Human Pluripotent Stem Cell-Derived Macrophages.

Stem Cell Reports 2020 05 30;14(5):940-955. Epub 2020 Apr 30.

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK; Oxford Parkinson's Disease Centre, University of Oxford, South Parks Road, Oxford OX1 3QX, UK. Electronic address:

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May 2020

Mechanism of Diol Dehydration by a Promiscuous Radical-SAM Enzyme Homologue of the Antiviral Enzyme Viperin (RSAD2).

Chembiochem 2020 06 27;21(11):1605-1612. Epub 2020 Feb 27.

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, OX1 3RE, Oxford, UK.

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June 2020

Lentiviral gene therapy vector with UCOE stably restores function in iPSC-derived neutrophils of a CDG patient.

Matters (Zur) 2018 23;2018. Epub 2018 May 23.

Systems and Cell Biology of Neurodegeneration, University of Zurich, James Martin Stem Cell Facility, University of Oxford, Division of Immunology, University Children's Hospital Zurich, Div. of Immunology, University Children's Hospital Zurich, Children's Research Center, Associated Group Institute for Regenerative Medicine, Department of Psychiatry, Sir William Dunn School of Pathology, University of Oxford, Icahn School of Medicine at Mount Sinai, HIV-Specific Immunity Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA, James Martin Stem Cell Facility, Sir William Dunn School of Pathology, University of Oxford, Professor emeritus University Children's Hospital Zürich, Division of Immunology, Professor emeritus Children's Research Center, Div. of Immunology, University Children's Hospital Zurich, Children's Research Center, Associated Group Institute for Regenerative Medicine, University of Zürich, Center for Applied Biotechnology and Molecular Medicine, University of Zürich, Div. of Immunology, University Children's Hospital Zürich, Children's Research Center, Associated Group Institute for Regenerative Medicine, University of Zürich.

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May 2018

Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages.

Sci Rep 2017 08 21;7(1):9003. Epub 2017 Aug 21.

James Martin Stem Cell Facility, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.

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August 2017

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response.

Stem Cell Reports 2017 06;8(6):1727-1742

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK; Oxford Parkinson's Disease Centre, University of Oxford, South Parks Road, Oxford OX1 3QX, UK. Electronic address:

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June 2017

LRRK2 in peripheral and central nervous system innate immunity: its link to Parkinson's disease.

Biochem Soc Trans 2017 Feb;45(1):131-139

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, U.K.

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February 2017

A novel real time imaging platform to quantify macrophage phagocytosis.

Biochem Pharmacol 2016 Sep 27;116:107-19. Epub 2016 Jul 27.

Sir William Dunn School of Pathology, South Parks Road, OX1 3RE Oxford, UK. Electronic address:

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September 2016

CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells.

Exp Hematol 2015 Oct 19;43(10):838-848.e3. Epub 2015 Jun 19.

Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom. Electronic address:

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October 2015

Physiological characterisation of human iPS-derived dopaminergic neurons.

PLoS One 2014 21;9(2):e87388. Epub 2014 Feb 21.

Oxford Parkinson's Disease Centre, University of Oxford, Oxford, United Kingdom ; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.

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January 2015

The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4.

PLoS One 2014 22;9(1):e86071. Epub 2014 Jan 22.

Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.

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November 2014

Differentially expressed, variant U1 snRNAs regulate gene expression in human cells.

Genome Res 2013 Feb 15;23(2):281-91. Epub 2012 Oct 15.

Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.

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February 2013

Episomal transgene expression in pluripotent stem cells.

Methods Mol Biol 2011 ;767:369-87

Molecular Neurodegeneration and Gene Therapy Research Group, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

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November 2011

Derivation and characterisation of the human embryonic stem cell line, OxF1.

In Vitro Cell Dev Biol Anim 2010 Apr 24;46(3-4):173-7. Epub 2010 Mar 24.

Nuffield Department of Obstetrics & Gynaecology, University of Oxford, The Womens Centre, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK.

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April 2010