William S Bush

William S Bush

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Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development.

Oncotarget 2019 Mar 5;10(19):1760-1774. Epub 2019 Mar 5.

Biomedical Data Science Department, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.18632/oncotarget.26678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442994PMC
March 2019

Racial Disparities in Lung Cancer Survival: The Contribution of Stage, Treatment, and Ancestry.

J Thorac Oncol 2018 10 6;13(10):1464-1473. Epub 2018 Jun 6.

Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.05.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153049PMC
October 2018

Local ancestry transitions modify snp-trait associations.

Pac Symp Biocomput 2018 ;23:424-435

Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN 37235, USA, ²Departments of Biological Sciences, Biomedical Informatics, and Computer Science, Vanderbilt University, Nashville, TN 37235, USA,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728664PMC
August 2018

INTEGRATING COMMUNITY-LEVEL DATA RESOURCES FOR PRECISION MEDICINE RESEARCH.

Pac Symp Biocomput 2018 ;23:618-622

Department of Population and Quantitative Health Sciences, Case Western Reserve University Cleveland, OH, 44106, USA,

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August 2018

Functional annotation of genomic variants in studies of late-onset Alzheimer's disease.

Bioinformatics 2018 08;34(16):2724-2731

Department of Population and Quantitative Health Sciences, Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1093/bioinformatics/bty177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084586PMC
August 2018

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk.

Authors:
Xuemei Ji Yohan Bossé Maria Teresa Landi Jiang Gui Xiangjun Xiao David Qian Philippe Joubert Maxime Lamontagne Yafang Li Ivan Gorlov Mariella de Biasi Younghun Han Olga Gorlova Rayjean J Hung Xifeng Wu James McKay Xuchen Zong Robert Carreras-Torres David C Christiani Neil Caporaso Mattias Johansson Geoffrey Liu Stig E Bojesen Loic Le Marchand Demetrios Albanes Heike Bickeböller Melinda C Aldrich William S Bush Adonina Tardon Gad Rennert Chu Chen M Dawn Teare John K Field Lambertus A Kiemeney Philip Lazarus Aage Haugen Stephen Lam Matthew B Schabath Angeline S Andrew Hongbing Shen Yun-Chul Hong Jian-Min Yuan Pier A Bertazzi Angela C Pesatori Yuanqing Ye Nancy Diao Li Su Ruyang Zhang Yonathan Brhane Natasha Leighl Jakob S Johansen Anders Mellemgaard Walid Saliba Christopher Haiman Lynne Wilkens Ana Fernandez-Somoano Guillermo Fernandez-Tardon Erik H F M van der Heijden Jin Hee Kim Juncheng Dai Zhibin Hu Michael P A Davies Michael W Marcus Hans Brunnström Jonas Manjer Olle Melander David C Muller Kim Overvad Antonia Trichopoulou Rosario Tumino Jennifer Doherty Gary E Goodman Angela Cox Fiona Taylor Penella Woll Irene Brüske Judith Manz Thomas Muley Angela Risch Albert Rosenberger Kjell Grankvist Mikael Johansson Frances Shepherd Ming-Sound Tsao Susanne M Arnold Eric B Haura Ciprian Bolca Ivana Holcatova Vladimir Janout Milica Kontic Jolanta Lissowska Anush Mukeria Simona Ognjanovic Tadeusz M Orlowski Ghislaine Scelo Beata Swiatkowska David Zaridze Per Bakke Vidar Skaug Shanbeh Zienolddiny Eric J Duell Lesley M Butler Woon-Puay Koh Yu-Tang Gao Richard Houlston John McLaughlin Victoria Stevens David C Nickle Ma'en Obeidat Wim Timens Bin Zhu Lei Song María Soler Artigas Martin D Tobin Louise V Wain Fangyi Gu Jinyoung Byun Ahsan Kamal Dakai Zhu Rachel F Tyndale Wei-Qi Wei Stephen Chanock Paul Brennan Christopher I Amos

Nat Commun 2018 08 13;9(1):3221. Epub 2018 Aug 13.

Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, 03750, NH, USA.

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http://dx.doi.org/10.1038/s41467-018-05074-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089967PMC
August 2018

Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.

Authors:
Joshua C Bis Xueqiu Jian Brian W Kunkle Yuning Chen Kara L Hamilton-Nelson William S Bush William J Salerno Daniel Lancour Yiyi Ma Alan E Renton Edoardo Marcora John J Farrell Yi Zhao Liming Qu Shahzad Ahmad Najaf Amin Philippe Amouyel Gary W Beecham Jennifer E Below Dominique Campion Camille Charbonnier Jaeyoon Chung Paul K Crane Carlos Cruchaga L Adrienne Cupples Jean-François Dartigues Stéphanie Debette Jean-François Deleuze Lucinda Fulton Stacey B Gabriel Emmanuelle Genin Richard A Gibbs Alison Goate Benjamin Grenier-Boley Namrata Gupta Jonathan L Haines Aki S Havulinna Seppo Helisalmi Mikko Hiltunen Daniel P Howrigan M Arfan Ikram Jaakko Kaprio Jan Konrad Amanda Kuzma Eric S Lander Mark Lathrop Terho Lehtimäki Honghuang Lin Kari Mattila Richard Mayeux Donna M Muzny Waleed Nasser Benjamin Neale Kwangsik Nho Gaël Nicolas Devanshi Patel Margaret A Pericak-Vance Markus Perola Bruce M Psaty Olivier Quenez Farid Rajabli Richard Redon Christiane Reitz Anne M Remes Veikko Salomaa Chloe Sarnowski Helena Schmidt Michael Schmidt Reinhold Schmidt Hilkka Soininen Timothy A Thornton Giuseppe Tosto Christophe Tzourio Sven J van der Lee Cornelia M van Duijn Badri Vardarajan Weixin Wang Ellen Wijsman Richard K Wilson Daniela Witten Kim C Worley Xiaoling Zhang Celine Bellenguez Jean-Charles Lambert Mitja I Kurki Aarno Palotie Mark Daly Eric Boerwinkle Kathryn L Lunetta Anita L Destefano Josée Dupuis Eden R Martin Gerard D Schellenberg Sudha Seshadri Adam C Naj Myriam Fornage Lindsay A Farrer

Mol Psychiatry 2018 Aug 14. Epub 2018 Aug 14.

Departments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41380-018-0112-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375806PMC
August 2018

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population.

Carcinogenesis 2018 03;39(3):336-346

Biomedical Data Science Department, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.1093/carcin/bgx113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248554PMC
March 2018

Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures.

Am J Hum Genet 2018 03 15;102(3):415-426. Epub 2018 Feb 15.

Department of Biomedical Informatics, Vanderbilt University, Nashville, TN 37232, USA; Department of Computer Science, Vanderbilt University, Nashville, TN 37212, USA; Center for Structural Biology, Vanderbilt University, Nashville, TN 37212, USA; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985282PMC
March 2018

Three-dimensional spatial analysis of missense variants in RTEL1 identifies pathogenic variants in patients with Familial Interstitial Pneumonia.

BMC Bioinformatics 2018 01 23;19(1):18. Epub 2018 Jan 23.

Department of Biological Sciences, Vanderbilt Genetics Institute, and Center for Structural Biology, Vanderbilt University, Nashville, USA.

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http://dx.doi.org/10.1186/s12859-018-2010-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781290PMC
January 2018

Germline Genetic Variants and Lung Cancer Survival in African Americans.

Cancer Epidemiol Biomarkers Prev 2017 08 15;26(8):1288-1295. Epub 2017 Jun 15.

Department of Thoracic Surgery, Vanderbilt University Medical School, Nashville, Tennessee.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-0998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540773PMC
August 2017

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.

J Natl Cancer Inst 2017 08;109(8)

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1093/jnci/djx084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448553PMC
August 2017

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

Authors:
James D McKay Rayjean J Hung Younghun Han Xuchen Zong Robert Carreras-Torres David C Christiani Neil E Caporaso Mattias Johansson Xiangjun Xiao Yafang Li Jinyoung Byun Alison Dunning Karen A Pooley David C Qian Xuemei Ji Geoffrey Liu Maria N Timofeeva Stig E Bojesen Xifeng Wu Loic Le Marchand Demetrios Albanes Heike Bickeböller Melinda C Aldrich William S Bush Adonina Tardon Gad Rennert M Dawn Teare John K Field Lambertus A Kiemeney Philip Lazarus Aage Haugen Stephen Lam Matthew B Schabath Angeline S Andrew Hongbing Shen Yun-Chul Hong Jian-Min Yuan Pier Alberto Bertazzi Angela C Pesatori Yuanqing Ye Nancy Diao Li Su Ruyang Zhang Yonathan Brhane Natasha Leighl Jakob S Johansen Anders Mellemgaard Walid Saliba Christopher A Haiman Lynne R Wilkens Ana Fernandez-Somoano Guillermo Fernandez-Tardon Henricus F M van der Heijden Jin Hee Kim Juncheng Dai Zhibin Hu Michael P A Davies Michael W Marcus Hans Brunnström Jonas Manjer Olle Melander David C Muller Kim Overvad Antonia Trichopoulou Rosario Tumino Jennifer A Doherty Matt P Barnett Chu Chen Gary E Goodman Angela Cox Fiona Taylor Penella Woll Irene Brüske H-Erich Wichmann Judith Manz Thomas R Muley Angela Risch Albert Rosenberger Kjell Grankvist Mikael Johansson Frances A Shepherd Ming-Sound Tsao Susanne M Arnold Eric B Haura Ciprian Bolca Ivana Holcatova Vladimir Janout Milica Kontic Jolanta Lissowska Anush Mukeria Simona Ognjanovic Tadeusz M Orlowski Ghislaine Scelo Beata Swiatkowska David Zaridze Per Bakke Vidar Skaug Shanbeh Zienolddiny Eric J Duell Lesley M Butler Woon-Puay Koh Yu-Tang Gao Richard S Houlston John McLaughlin Victoria L Stevens Philippe Joubert Maxime Lamontagne David C Nickle Ma'en Obeidat Wim Timens Bin Zhu Lei Song Linda Kachuri María Soler Artigas Martin D Tobin Louise V Wain Thorunn Rafnar Thorgeir E Thorgeirsson Gunnar W Reginsson Kari Stefansson Dana B Hancock Laura J Bierut Margaret R Spitz Nathan C Gaddis Sharon M Lutz Fangyi Gu Eric O Johnson Ahsan Kamal Claudio Pikielny Dakai Zhu Sara Lindströem Xia Jiang Rachel F Tyndale Georgia Chenevix-Trench Jonathan Beesley Yohan Bossé Stephen Chanock Paul Brennan Maria Teresa Landi Christopher I Amos

Nat Genet 2017 Jul 12;49(7):1126-1132. Epub 2017 Jun 12.

Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

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http://dx.doi.org/10.1038/ng.3892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510465PMC
July 2017

Extracting Country-of-Origin from Electronic Health Records for Gene- Environment Studies as Part of the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) Study.

AMIA Jt Summits Transl Sci Proc 2017 26;2017:50-57. Epub 2017 Jul 26.

Department of Epidemiology and Biostatistics, Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543359PMC
July 2017

Reducing Clinical Noise for Body Mass Index Measures Due to Unit and Transcription Errors in the Electronic Health Record.

AMIA Jt Summits Transl Sci Proc 2017 26;2017:102-111. Epub 2017 Jul 26.

Institute for Computational Biology, Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543370PMC
July 2017

Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci.

Hum Genet 2017 06 8;136(6):771-800. Epub 2017 Apr 8.

Department of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1007/s00439-017-1787-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485655PMC
June 2017

Introducing COCOS: codon consequence scanner for annotating reading frame changes induced by stop-lost and frame shift variants.

Bioinformatics 2017 May;33(10):1561-1562

Department of Epidemiology and Biostatistics, Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423451PMC
May 2017

Predicting Incident Coronary Heart Disease Many Markers at a Time.

Circ Cardiovasc Genet 2016 12;9(6):472-473

From the Department of Epidemiology and Biostatistics, Institute for Computational Biology, Case Western Reserve University, Cleveland, OH.

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001645DOI Listing
December 2016

Are Interactions between cis-Regulatory Variants Evidence for Biological Epistasis or Statistical Artifacts?

Am J Hum Genet 2016 Oct 15;99(4):817-830. Epub 2016 Sep 15.

Institute for Computational Biology, Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 44106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065654PMC
October 2016

Analysis of Heritability Using Genome-Wide Data.

Curr Protoc Hum Genet 2016 10 11;91:1.30.1-1.30.10. Epub 2016 Oct 11.

Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio.

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http://dx.doi.org/10.1002/cphg.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127448PMC
October 2016

eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants.

BMC Med Genomics 2016 08 12;9 Suppl 1:32. Epub 2016 Aug 12.

Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, South Africa.

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http://dx.doi.org/10.1186/s12920-016-0191-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989894PMC
August 2016

Evidence for extensive pleiotropy among pharmacogenes.

Pharmacogenomics 2016 06 1;17(8):853-66. Epub 2016 Jun 1.

Department of Epidemiology & Biostatistics, Institute for Computational Biology, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.2217/pgs-2015-0007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352965PMC
June 2016

Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits.

Hum Hered 2015 28;79(3-4):137-46. Epub 2015 Jul 28.

Department of Epidemiology and Biostatistics, Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1159/000381805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528966PMC
April 2016

Unravelling the human genome-phenome relationship using phenome-wide association studies.

Nat Rev Genet 2016 Mar 15;17(3):129-45. Epub 2016 Feb 15.

Department of Epidemiology and Biostatistics, Institute for Computational Biology, Case Western Reserve University, Wolstein Research Building, 2103 Cornell Road, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1038/nrg.2015.36DOI Listing
March 2016

Hand position biases processing toward task irrelevant flankers.

J Exp Psychol Hum Percept Perform 2016 Feb 21;42(2):151-7. Epub 2015 Sep 21.

Department of Psychology, University of Iowa.

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http://dx.doi.org/10.1037/xhp0000104DOI Listing
February 2016

The phenotypic legacy of admixture between modern humans and Neandertals.

Science 2016 Feb;351(6274):737-41

Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA. Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA. Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA. Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1126/science.aad2149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849557PMC
February 2016

In Silico Functional Annotation of Genomic Variation.

Curr Protoc Hum Genet 2016 Jan 1;88:Unit 6.15. Epub 2016 Jan 1.

Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio.

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http://dx.doi.org/10.1002/0471142905.hg0615s88DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722816PMC
January 2016

Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry.

BioData Min 2015 11;8:35. Epub 2015 Nov 11.

Institute for Computational Biology, Department of Epidemiology and Biostatistics, Case Western Reserve University, Wolstein Research Building, 2103 Cornell Road, Suite 2527, Cleveland, OH 44106 USA.

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http://dx.doi.org/10.1186/s13040-015-0068-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642611PMC
November 2015

Accuracy of administratively-assigned ancestry for diverse populations in an electronic medical record-linked biobank.

PLoS One 2014 4;9(6):e99161. Epub 2014 Jun 4.

Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099161PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045967PMC
October 2015

GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension.

Neurotox Res 2015 Oct 21;28(3):232-8. Epub 2015 Jul 21.

Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Vanderbilt University Medical Center, 2525 West End Ave, 12th Floor, Suite 1200, Nashville, TN, 37203, USA,

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http://link.springer.com/10.1007/s12640-015-9541-0
Publisher Site
http://dx.doi.org/10.1007/s12640-015-9541-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625986PMC
October 2015

Estimating cumulative pathway effects on risk for age-related macular degeneration using mixed linear models.

BMC Bioinformatics 2015 Oct 14;16:329. Epub 2015 Oct 14.

Institute for Computational Biology, Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1186/s12859-015-0760-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606903PMC
October 2015

Gene expression in cell lines from propionic acidemia patients, carrier parents, and controls.

Mol Genet Metab 2015 Aug 8;115(4):174-9. Epub 2015 May 8.

Center for Biomedical Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2015.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522369PMC
August 2015

Phenotyping Adverse Drug Reactions: Statin-Related Myotoxicity.

AMIA Jt Summits Transl Sci Proc 2015 25;2015:466-70. Epub 2015 Mar 25.

Department of Epidemiology & Biostatistics, Case Western Reserve University, Cleveland, OH.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525276PMC
August 2015

Sex-Specific Parental Effects on Offspring Lipid Levels.

J Am Heart Assoc 2015 Jun 30;4(7). Epub 2015 Jun 30.

Department of Genetics, Geisel School of Medicine, Dartmouth College, Hanover, NH (R.S.S., J.B., S.M.W.).

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http://dx.doi.org/10.1161/JAHA.115.001951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608079PMC
June 2015

Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles.

Am J Physiol Endocrinol Metab 2015 Apr 3;308(7):E592-602. Epub 2015 Feb 3.

Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee

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http://dx.doi.org/10.1152/ajpendo.00437.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385877PMC
April 2015

Bioinformatics challenges in genome-wide association studies (GWAS).

Methods Mol Biol 2014 ;1168:63-81

Department of Genetics, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.1007/978-1-4939-0847-9_5DOI Listing
January 2015

SecureMA: protecting participant privacy in genetic association meta-analysis.

Bioinformatics 2014 Dec 21;30(23):3334-41. Epub 2014 Aug 21.

Department of Electrical Engineering & Computer Science, Vanderbilt University, Nashville, TN 37232, USA, Department of Computer Science, University of Texas at Dallas, Richardson, TX 75080, USA, Department of Biomedical Informatics, Center for Human Genetics Research, Department of Molecular Physiology and Biophysics and Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA Department of Electrical Engineering & Computer Science, Vanderbilt University, Nashville, TN 37232, USA, Department of Computer Science, University of Texas at Dallas, Richardson, TX 75080, USA, Department of Biomedical Informatics, Center for Human Genetics Research, Department of Molecular Physiology and Biophysics and Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296153PMC
December 2014

Differential effect of one versus two hands on visual processing.

Cognition 2014 Oct 21;133(1):232-7. Epub 2014 Jul 21.

Department of Psychology, University of Iowa, Iowa City, United States.

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http://dx.doi.org/10.1016/j.cognition.2014.06.014DOI Listing
October 2014

eMERGEing progress in genomics-the first seven years.

Front Genet 2014 17;5:184. Epub 2014 Jun 17.

Department of Biochemistry and Molecular Biology, Pennsylvania State University University Park, PA, USA ; Center for Systems Genomics, Pennsylvania State University University Park, PA, USA.

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http://journal.frontiersin.org/article/10.3389/fgene.2014.00
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http://dx.doi.org/10.3389/fgene.2014.00184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060012PMC
July 2014

Automated quantification of pancreatic β-cell mass.

Am J Physiol Endocrinol Metab 2014 Jun 22;306(12):E1460-7. Epub 2014 Apr 22.

Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; and

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http://dx.doi.org/10.1152/ajpendo.00591.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059986PMC
June 2014

Genotype Correlation Analysis Reveals Pathway-Based Functional Disequilibrium and Potential Epistasis in the Human Interactome.

Appl Evol Comput (2014) 2014 Apr 29;8602:890-901. Epub 2014 Nov 29.

Institute for Computational Biology, Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1007/978-3-662-45523-4_72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382931PMC
April 2014

Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia.

J Natl Cancer Inst 2014 Apr 28;106(4):dju061. Epub 2014 Mar 28.

Affiliations of authors: Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (SLP, FRS, CAH); Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA (MDF, JMK, AY, YL, UP, CC, CK); Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and Medical Research Council Human Genetics Unit, Edinburgh, UK (MT); Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI (CPC, LRW, LL); Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH (YH, CIA); Department of Epidemiology (S-AL, AB, KEN, GH) and Carolina Center for Genome Sciences (KEN), University of North Carolina, Chapel Hill, NC; Molecular Physiology and Biophysics (LD, DCC), Center for Human Genetics Research (LD, RG, HD, DCC, WSB), Vanderbilt Epidemiology Center (JHF), and Biomedical Informatics (WSB), Vanderbilt University, Nashville, TN; Division of Genomic Medicine, National Human Genome Research Institute (LH), and Division of Cancer Epidemiology and Genetics, National Cancer Institute (DA, NC, MTL), National Institutes of Health, Bethesda, MD; Department of Statistics and Biostatistics, Rutgers University, Piscataway, NJ (SB); Information Sciences Institute, University of Southern California, Marina del Rey, CA (ED); Department of Oncology, School of Medicine, Wayne State University, Detroit, Michigan (MLC); M.D. Anderson Cancer Center, Houston, TX (WC, MP); Harvard University School of Public Health, Boston, MA (DCC); Roy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, The University of Liverpool Cancer Research Centre, Institute of Translational Medicine, The University of Liverpool, Liverpool, UK (JKF); Department of Genetic Epidemiology, University Medical Centre Göttingen, Göttingen, Germany (HB); DKFZ-German Cancer Research Center and Translatio

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982896PMC
April 2014

Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes.

Pain 2013 Dec 28;154(12):2853-9. Epub 2013 Aug 28.

Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN, USA. Electronic address:

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December 2013

Automated extraction of clinical traits of multiple sclerosis in electronic medical records.

J Am Med Inform Assoc 2013 Dec 22;20(e2):e334-40. Epub 2013 Oct 22.

Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861927PMC
December 2013

Multivariate analysis of regulatory SNPs: empowering personal genomics by considering cis-epistasis and heterogeneity.

Pac Symp Biocomput 2011 :276-87

Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN 37232, United States.

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November 2013

Rapid storage and retrieval of genomic intervals from a relational database system using nested containment lists.

Database (Oxford) 2013 26;2013:bat056. Epub 2013 Jul 26.

Department of Biomedical Informatics, Center for Human Genetics Research, Vanderbilt University, 2215 Garland Ave, Nashville, TN 37232, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724366PMC
October 2013

ICD-9 tobacco use codes are effective identifiers of smoking status.

J Am Med Inform Assoc 2013 Jul-Aug;20(4):652-8. Epub 2013 Feb 9.

Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721171PMC
September 2013

Putting pleiotropy and selection into context defines a new paradigm for interpreting genetic data.

Circ Cardiovasc Genet 2013 Jun 24;6(3):299-307. Epub 2013 Apr 24.

Division of Cardiovascular Medicine, Section of Cardiovascular Disease Prevention, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889706PMC
June 2013

Chapter 11: Genome-wide association studies.

PLoS Comput Biol 2012 27;8(12):e1002822. Epub 2012 Dec 27.

Department of Biomedical Informatics, Center for Human Genetics Research, Vanderbilt University Medical School, Nashville, Tennessee, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531285PMC
May 2013

Knowledge-constrained K-medoids Clustering of Regulatory Rare Alleles for Burden Tests.

Evol Comput Mach Learn Data Min Bioinform 2013 ;7833:35-42

Center for Human Genetics Research, Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274942PMC
January 2013

A comparison of cataloged variation between International HapMap Consortium and 1000 Genomes Project data.

J Am Med Inform Assoc 2012 Mar-Apr;19(2):289-94

Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277631PMC
May 2012

Genetic analysis of biological pathway data through genomic randomization.

Hum Genet 2011 May 30;129(5):563-71. Epub 2011 Jan 30.

Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107984PMC
May 2011

Genome simulation approaches for synthesizing in silico datasets for human genomics.

Adv Genet 2010 ;72:1-24

Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, USA.

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November 2010

Split attention as part of a flexible attentional system for complex scenes: comment on Jans, Peters, and De Weerd (2010).

Psychol Rev 2010 Apr;117(2):685-96

Department of Psychology, University of Massachusetts, Amherst, MA 01003, USA.

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April 2010

Visualizing SNP statistics in the context of linkage disequilibrium using LD-Plus.

Bioinformatics 2010 Feb 3;26(4):578-9. Epub 2010 Feb 3.

Department of Molecular Physiology, Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820673PMC
February 2010

Overview of linkage analysis in complex traits.

Curr Protoc Hum Genet 2010 Jan;Chapter 1:Unit 1.9.1-18

Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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January 2010

Exploring epistasis in candidate genes for rheumatoid arthritis.

BMC Proc 2007 18;1 Suppl 1:S70. Epub 2007 Dec 18.

Department of Molecular Physiology and Biophysics, Center for Human Genetics Research, Vanderbilt University Medical Center, 21st Avenue South and Garland Avenue, Nashville, Tennessee 37232, USA.

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http://dx.doi.org/10.1186/1753-6561-1-s1-s70DOI Listing
December 2009

LD-spline: mapping SNPs on genotyping platforms to genomic regions using patterns of linkage disequilibrium.

BioData Min 2009 Dec 3;2(1). Epub 2009 Dec 3.

Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795743PMC
December 2009

Genetic variation in the rhythmonome: ethnic variation and haplotype structure in candidate genes for arrhythmias.

Pharmacogenomics 2009 Jun;10(6):1043-53

Center for Human Genetics Research & Department of Molecular Physiology & Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.2217/pgs.09.67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746955PMC
June 2009

Biofilter: a knowledge-integration system for the multi-locus analysis of genome-wide association studies.

Pac Symp Biocomput 2009 :368-79

Center for Human Genetics Research, Vanderbilt University, Nashville, TN 37232, USA.

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March 2009

Alternative contingency table measures improve the power and detection of multifactor dimensionality reduction.

BMC Bioinformatics 2008 May 16;9:238. Epub 2008 May 16.

Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2412877PMC
May 2008

A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction.

Genet Epidemiol 2007 May;31(4):306-15

Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee.

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May 2007

Genetic Programming Neural Networks: A Powerful Bioinformatics Tool for Human Genetics.

Appl Soft Comput 2007 Jan;7(1):471-479

Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, 519 Light Hall, Nashville, TN 37232.

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http://dx.doi.org/10.1016/j.asoc.2006.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952963PMC
January 2007

Parallel multifactor dimensionality reduction: a tool for the large-scale analysis of gene-gene interactions.

Bioinformatics 2006 Sep 29;22(17):2173-4. Epub 2006 Jun 29.

Center for Human Genetics Research, Vanderbilt University, Nashville, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939609PMC
September 2006

Antibody-specific detection of caveolin-1 in subapical compartments of MDCK cells.

Histochem Cell Biol 2006 Jul 28;126(1):27-34. Epub 2006 Jan 28.

Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, 718 Light Hall, Nashville, TN 37232, USA.

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July 2006