William R Swindell

William R Swindell

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William R Swindell

William R Swindell

Publications by authors named "William R Swindell"

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Correction to: GM6 Attenuates Alzheimer's Disease Pathology in APP Mice.

Mol Neurobiol 2019 Sep;56(9):6397

Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA.

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http://dx.doi.org/10.1007/s12035-019-1558-6DOI Listing
September 2019

ALS blood expression profiling identifies new biomarkers, patient subgroups, and evidence for neutrophilia and hypoxia.

J Transl Med 2019 May 22;17(1):170. Epub 2019 May 22.

Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, 45701, USA.

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http://dx.doi.org/10.1186/s12967-019-1909-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530130PMC
May 2019

Putting a strain on diversity.

EMBO J 2018 Nov 2;37(22). Epub 2018 Nov 2.

Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, USA.

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http://dx.doi.org/10.15252/embj.2018100862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236330PMC
November 2018

Rapamycin in mice.

Aging (Albany NY) 2017 Sep;9(9):1941-1942

Ohio University Heritage College of Osteopathic Medicine, Athens, OH 45701, USA.

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http://dx.doi.org/10.18632/aging.101289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636660PMC
September 2017

Meta-Analysis of 29 Experiments Evaluating the Effects of Rapamycin on Life Span in the Laboratory Mouse.

J Gerontol A Biol Sci Med Sci 2017 Aug;72(8):1024-1032

Heritage College of Osteopathic Medicine, Ohio University, Athens.

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https://academic.oup.com/biomedgerontology/article-lookup/do
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http://dx.doi.org/10.1093/gerona/glw153DOI Listing
August 2017

Dual Role of Act1 in Keratinocyte Differentiation and Host Defense: TRAF3IP2 Silencing Alters Keratinocyte Differentiation and Inhibits IL-17 Responses.

J Invest Dermatol 2017 07 6;137(7):1501-1511. Epub 2017 Mar 6.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Ann Arbor Veterans Affairs Health System, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.12.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554967PMC
July 2017

Induction of Alternative Proinflammatory Cytokines Accounts for Sustained Psoriasiform Skin Inflammation in IL-17C+IL-6KO Mice.

J Invest Dermatol 2017 03 27;137(3):696-705. Epub 2016 Oct 27.

Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA; Murdough Family Center for Psoriasis, Cleveland, Ohio, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326585PMC
March 2017

Cross-Disease Transcriptomics: Unique IL-17A Signaling in Psoriasis Lesions and an Autoimmune PBMC Signature.

J Invest Dermatol 2016 09 17;136(9):1820-1830. Epub 2016 May 17.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1016/j.jid.2016.04.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234565PMC
September 2016

Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia?

J Invest Dermatol 2016 09 14;136(9):1792-1800. Epub 2016 Jun 14.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Ann Arbor Veterans Affairs Hospital, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.05.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112032PMC
September 2016

Nuclear respiratory factor 2 induces SIRT3 expression.

Aging Cell 2015 Oct 24;14(5):818-25. Epub 2015 Jun 24.

Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1111/acel.12360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568969PMC
October 2015

Comparison of molecular signatures from multiple skin diseases identifies mechanisms of immunopathogenesis.

J Invest Dermatol 2015 Jan 11;135(1):151-159. Epub 2014 Aug 11.

Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, California, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268388PMC
January 2015

Integrative RNA-seq and microarray data analysis reveals GC content and gene length biases in the psoriasis transcriptome.

Physiol Genomics 2014 Aug 20;46(15):533-46. Epub 2014 May 20.

Department of Dermatology, University of Michigan School of Medicine, Ann Arbor, Michigan.

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http://dx.doi.org/10.1152/physiolgenomics.00022.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121624PMC
August 2014

IL-32 is a molecular marker of a host defense network in human tuberculosis.

Sci Transl Med 2014 Aug;6(250):250ra114

Division of Dermatology, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, CA 90095, USA. Department of Microbiology, Immunology and Molecular Genetics, UCLA, Los Angeles, CA 90095 USA.

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http://dx.doi.org/10.1126/scitranslmed.3009546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175914PMC
August 2014

Modulation of epidermal transcription circuits in psoriasis: new links between inflammation and hyperproliferation.

PLoS One 2013 15;8(11):e79253. Epub 2013 Nov 15.

Department of Dermatology, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079253PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829857PMC
July 2014

Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms.

J Invest Dermatol 2014 Jul 17;134(7):1828-1838. Epub 2014 Jan 17.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Ann Arbor Veterans Affairs Hospital, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057954PMC
July 2014

Intertissue control of the nucleolus via a myokine-dependent longevity pathway.

Cell Rep 2014 Jun 29;7(5):1481-1494. Epub 2014 May 29.

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.celrep.2014.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125979PMC
June 2014

Cellular dissection of psoriasis for transcriptome analyses and the post-GWAS era.

BMC Med Genomics 2014 May 22;7:27. Epub 2014 May 22.

Department of Dermatology, University of Michigan School of Medicine, Ann Arbor, MI 48109-2200, USA.

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http://dx.doi.org/10.1186/1755-8794-7-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060870PMC
May 2014

Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice.

Elife 2013 Oct 29;2:e01098. Epub 2013 Oct 29.

Department of Internal Medicine , Southern Illinois University School of Medicine , Springfield , United States.

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http://dx.doi.org/10.7554/eLife.01098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810783PMC
October 2013

Robust shifts in S100a9 expression with aging: a novel mechanism for chronic inflammation.

Sci Rep 2013 5;3:1215. Epub 2013 Feb 5.

Department of Dermatology, University of Michigan School of Medicine, Ann Arbor, MI 48109-2200, USA.

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http://dx.doi.org/10.1038/srep01215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564041PMC
August 2013

Dissecting the psoriasis transcriptome: inflammatory- and cytokine-driven gene expression in lesions from 163 patients.

BMC Genomics 2013 Aug 1;14:527. Epub 2013 Aug 1.

Department of Dermatology, University of Michigan School of Medicine, Ann Arbor, MI 48109-2200, USA.

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http://dx.doi.org/10.1186/1471-2164-14-527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751090PMC
August 2013

Alteration of the EphA2/Ephrin-A signaling axis in psoriatic epidermis.

J Invest Dermatol 2013 Mar 29;133(3):712-722. Epub 2012 Nov 29.

Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; Department of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2012.391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570705PMC
March 2013

Dietary restriction in rats and mice: a meta-analysis and review of the evidence for genotype-dependent effects on lifespan.

Ageing Res Rev 2012 Apr 23;11(2):254-70. Epub 2011 Dec 23.

Department of Genetics, Harvard Medical School, Boston, MA 02115, United States.

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http://dx.doi.org/10.1016/j.arr.2011.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299887PMC
April 2012

Metallothionein and the biology of aging.

Ageing Res Rev 2011 Jan 8;10(1):132-45. Epub 2010 Oct 8.

Department of Genetics, Harvard Medical School New Research Building, Room 0464, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15681637100008
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http://dx.doi.org/10.1016/j.arr.2010.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386784PMC
January 2011

In vivo analysis of gene expression in long-lived mice lacking the pregnancy-associated plasma protein A (PappA) gene.

Exp Gerontol 2010 May 1;45(5):366-74. Epub 2010 Mar 1.

University of Michigan, Department of Pathology and Geriatrics Center, Ann Arbor, MI 48109-2200, USA.

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http://dx.doi.org/10.1016/j.exger.2010.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860881PMC
May 2010

Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse.

BMC Genomics 2009 Dec 7;10:585. Epub 2009 Dec 7.

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.

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http://dx.doi.org/10.1186/1471-2164-10-585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795771PMC
December 2009

Endocrine regulation of heat shock protein mRNA levels in long-lived dwarf mice.

Mech Ageing Dev 2009 Jun 8;130(6):393-400. Epub 2009 Apr 8.

University of Michigan, Department of Pathology and Geriatrics Center, Ann Arbor, MI 48109-2200, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S004763740900051
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http://dx.doi.org/10.1016/j.mad.2009.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718793PMC
June 2009

Heat shock proteins in long-lived worms and mice with insulin/insulin-like signaling mutations.

Aging (Albany NY) 2009 Jun 15;1(6):573-7. Epub 2009 Jun 15.

University of Michigan, Departments of Pathology and Geriatrics, Ann Arbor MI 48109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806032PMC
http://dx.doi.org/10.18632/aging.100058DOI Listing
June 2009

Accelerated failure time models provide a useful statistical framework for aging research.

Exp Gerontol 2009 Mar 25;44(3):190-200. Epub 2008 Oct 25.

Departments of Pathology and Geriatrics, University of Michigan, Ann Arbor, MI 48109-2200, USA.

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http://dx.doi.org/10.1016/j.exger.2008.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718836PMC
March 2009

Genes regulated by caloric restriction have unique roles within transcriptional networks.

Mech Ageing Dev 2008 Oct 27;129(10):580-92. Epub 2008 Jun 27.

Department of Pathology, University of Michigan, Ann Arbor, MI 48109-2200, USA.

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http://dx.doi.org/10.1016/j.mad.2008.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688445PMC
October 2008

How long will my mouse live? Machine learning approaches for prediction of mouse life span.

J Gerontol A Biol Sci Med Sci 2008 Sep;63(9):895-906

Department of Pathology and Geriatrics Center, University of Michigan, Ann Arbor, MI 48109-2200, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693389PMC
http://dx.doi.org/10.1093/gerona/63.9.895DOI Listing
September 2008

Comparative analysis of microarray data identifies common responses to caloric restriction among mouse tissues.

Mech Ageing Dev 2008 Mar 21;129(3):138-53. Epub 2007 Nov 21.

Department of Pathology, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI 48103, United States.

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http://dx.doi.org/10.1016/j.mad.2007.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702675PMC
March 2008

Gene expression profiling of long-lived dwarf mice: longevity-associated genes and relationships with diet, gender and aging.

BMC Genomics 2007 Oct 3;8:353. Epub 2007 Oct 3.

Department of Pathology, University of Michigan, 3118 BSRB, Ann Arbor, MI, USA.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-8-353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094713PMC
October 2007

Genotype-by-age interaction and identification of longevity-associated genes from microarray data.

Age (Dordr) 2007 Sep 21;29(2-3):97-102. Epub 2007 Jun 21.

Department of Statistics and Probability, Michigan State University, A-413 Wells Hall, East Lansing, MI 48824, USA.

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http://link.springer.com/10.1007/s11357-007-9033-0
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http://dx.doi.org/10.1007/s11357-007-9033-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267658PMC
September 2007

The association among gene expression responses to nine abiotic stress treatments in Arabidopsis thaliana.

Genetics 2006 Dec 8;174(4):1811-24. Epub 2006 Oct 8.

Department of Probability and Statistics, Michigan State University, East Lansing, Michigan 48824, USA.

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http://www.genetics.org/cgi/doi/10.1534/genetics.106.061374
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http://dx.doi.org/10.1534/genetics.106.061374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698639PMC
December 2006

Selection and inbreeding depression: effects of inbreeding rate and inbreeding environment.

Evolution 2006 May;60(5):1014-22

Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio 43403, USA.

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May 2006

Associations between environmental stress, selection history, and quantitative genetic variation in Drosophila melanogaster.

Genetica 2006 May;127(1-3):311-20

Department of Biological Sciences, Bowling Green State University, Bowling Green, OH 43403-0212, USA.

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http://link.springer.com/10.1007/s10709-005-5240-8
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http://dx.doi.org/10.1007/s10709-005-5240-8DOI Listing
May 2006

Ancestral inbreeding reduces the magnitude of inbreeding depression in Drosophila melanogaster.

Evolution 2006 Apr;60(4):762-7

Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio 43403-0212, USA.

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April 2006

Inbreeding depression and male survivorship in Drosophila: implications for senescence theory.

Genetics 2006 Jan 3;172(1):317-27. Epub 2005 Oct 3.

Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio 43403, USA.

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http://dx.doi.org/10.1534/genetics.105.045740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456160PMC
January 2006

Modeling the adaptive potential of isolated populations: experimental simulations using Drosophila.

Evolution 2005 Oct;59(10):2159-69

Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio 43403, USA.

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October 2005