Publications by authors named "William R Drobyski"

56Publications

Ixazomib for Chronic Graft-versus-Host Disease Prophylaxis following Allogeneic Hematopoietic Cell Transplantation.

Biol Blood Marrow Transplant 2020 Oct 9;26(10):1876-1885. Epub 2020 Jul 9.

Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin; Blood and Marrow Transplant & Cellular Therapy Program, Froedtert & Medical College of Wisconsin, Milwaukee, Wisconsin; Center for International Blood and Marrow Transplant Research, Milwaukee Campus, Milwaukee, Wisconsin. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2020.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571859PMC
October 2020

Fludarabine/Busulfan Conditioning-Based Allogeneic Hematopoietic Cell Transplantation for Myelofibrosis: Role of Ruxolitinib in Improving Survival Outcomes.

Biol Blood Marrow Transplant 2020 May 23;26(5):893-901. Epub 2020 Jan 23.

Blood and Marrow Transplant & Cellular Therapy Program, Medical College of Wisconsin, Milwaukee, Wisconsin; Division of Hematology/Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2020.01.010DOI Listing
May 2020

Inflammatory Cytokine Networks in Gastrointestinal Tract Graft vs. Host Disease.

Front Immunol 2019 22;10:163. Epub 2019 Feb 22.

Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.00163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395399PMC
January 2020

Impact of Obesity on Clinical Outcomes of Elderly Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Myeloid Malignancies.

Biol Blood Marrow Transplant 2019 01 19;25(1):e33-e38. Epub 2018 Sep 19.

Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee Wisconsin. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2018.08.031DOI Listing
January 2019

Tocilizumab for the treatment of severe steroid-refractory acute graft-versus-host disease of the lower gastrointestinal tract.

Bone Marrow Transplant 2019 02 24;54(2):212-217. Epub 2018 May 24.

Blood and Marrow Transplantation Program, Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41409-018-0236-z
Publisher Site
http://dx.doi.org/10.1038/s41409-018-0236-zDOI Listing
February 2019

Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors.

Int J Cancer 2018 08 30;143(4):886-896. Epub 2018 Mar 30.

Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, RM C4930, 8701 Watertown Plank Rd, Milwaukee, WI, 53226.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.31366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041131PMC
August 2018

Etanercept and Corticosteroid Therapy for the Treatment of Late-Onset Idiopathic Pneumonia Syndrome.

Biol Blood Marrow Transplant 2017 Nov 27;23(11):1955-1960. Epub 2017 Jul 27.

Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2017.07.019DOI Listing
November 2017

Alpha-1-antitrypsin for the treatment of steroid-refractory acute gastrointestinal graft-versus-host disease.

Am J Hematol 2017 Oct 29;92(10):E610-E611. Epub 2017 Jul 29.

Medical College of Wisconsin, Blood and Marrow Transplant Program, Milwaukee, Wisconsin.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajh.24850DOI Listing
October 2017

Effects of Donor Vitamin A Deficiency and Pharmacologic Modulation of Donor T Cell Retinoic Acid Pathway on the Severity of Experimental Graft-versus-Host Disease.

Biol Blood Marrow Transplant 2016 12 3;22(12):2141-2148. Epub 2016 Sep 3.

Division of Hematology & Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin; Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2016.09.001DOI Listing
December 2016

Engraftment Syndrome after Autologous Stem Cell Transplantation: An Update Unifying the Definition and Management Approach.

Biol Blood Marrow Transplant 2015 Dec 29;21(12):2061-2068. Epub 2015 Aug 29.

Division of Hematology and Oncology, Department of Internal Medicine, The Medical College of Wisconsin, Milwaukee, Wisconsin.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2015.08.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639405PMC
December 2015

The role of regulatory T cells in the biology of graft versus host disease.

Front Immunol 2013 24;4:163. Epub 2013 Jun 24.

Department of Microbiology, Medical College of Wisconsin , Milwaukee, WI , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2013.00163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690651PMC
July 2013

CD8+ Foxp3+ regulatory T cells are induced during graft-versus-host disease and mitigate disease severity.

J Immunol 2012 Jul 30;189(1):464-74. Epub 2012 May 30.

Bone Marrow Transplant Program, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1200886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381996PMC
July 2012

Emergence of T cells that recognize nonpolymorphic antigens during graft-versus- host disease.

Blood 2012 Jun 10;119(26):6354-64. Epub 2012 Apr 10.

Bone Marrow Transplant Program, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2012-01-401596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383195PMC
June 2012

Tocilizumab for the treatment of steroid refractory graft-versus-host disease.

Biol Blood Marrow Transplant 2011 Dec 13;17(12):1862-8. Epub 2011 Jul 13.

Bone Marrow Transplant Program, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2011.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716013PMC
December 2011

Instability of Foxp3 expression limits the ability of induced regulatory T cells to mitigate graft versus host disease.

Clin Cancer Res 2011 Jun 10;17(12):3969-83. Epub 2011 May 10.

Bone Marrow Transplant Program and the Departments of Microbiology, Pathology, and Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-10-3347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117905PMC
June 2011

Immunosuppressive effects of multiple myeloma are overcome by PD-L1 blockade.

Biol Blood Marrow Transplant 2011 Aug 12;17(8):1133-45. Epub 2011 Apr 12.

Department of Pediatrics, Division of Hematology/Oncology, Milwaukee, Wisconsin, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10838791110016
Publisher Site
http://dx.doi.org/10.1016/j.bbmt.2011.03.011DOI Listing
August 2011

Gastrointestinal pathology of autologous graft-versus-host disease following hematopoietic stem cell transplantation: a clinicopathological study of 17 cases.

Mod Pathol 2011 Jan 15;24(1):117-25. Epub 2010 Oct 15.

Department of Pathology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2010.163DOI Listing
January 2011

Immune reconstitution: how it should work, what's broken, and why it matters.

Biol Blood Marrow Transplant 2010 Jan 9;16(1 Suppl):S133-7. Epub 2009 Oct 9.

Experimental Transplantation and Immunology Branch, CCR, NCI, Bethesda, Maryland 20892-1907, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2009.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832716PMC
January 2010

Interleukin 17 is not required for autoimmune-mediated pathologic damage during chronic graft-versus-host disease.

Biol Blood Marrow Transplant 2010 Jan 17;16(1):123-8. Epub 2009 Sep 17.

Bone Marrow Transplant Program, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10838791090041
Publisher Site
http://dx.doi.org/10.1016/j.bbmt.2009.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804961PMC
January 2010

Captopril to mitigate chronic renal failure after hematopoietic stem cell transplantation: a randomized controlled trial.

Int J Radiat Oncol Biol Phys 2008 Apr 29;70(5):1546-51. Epub 2007 Oct 29.

Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2007.08.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386758PMC
April 2008

Gammadelta T cells do not require fully functional cytotoxic pathways or the ability to recognize recipient alloantigens to prevent graft rejection.

Biol Blood Marrow Transplant 2006 Nov;12(11):1125-34

Bone Marrow Transplant Program, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10838791060052
Publisher Site
http://dx.doi.org/10.1016/j.bbmt.2006.08.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1679815PMC
November 2006

NF-kappaB as a target for the prevention of graft-versus-host disease: comparative efficacy of bortezomib and PS-1145.

Blood 2006 Jan 20;107(2):827-34. Epub 2005 Sep 20.

Bone Marrow Transplant Program and the Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2005-05-1820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895627PMC
January 2006

Emergent autoimmunity in graft-versus-host disease.

Blood 2005 Jun 3;105(12):4885-91. Epub 2005 Mar 3.

Bone Marrow Transplant Program, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2004-12-49
Publisher Site
http://dx.doi.org/10.1182/blood-2004-12-4980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894995PMC
June 2005

Temporal discordance between graft-versus-leukemia and graft-versus-host responses: a strategy for the separation of graft-versus-leukemia/graft-versus-host reactivity?

Biol Blood Marrow Transplant 2004 Nov;10(11):743-7

Bone Marrow Transplant Program, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2004.07.006DOI Listing
November 2004

Host conditioning is a primary determinant in modulating the effect of IL-7 on murine graft-versus-host disease.

J Immunol 2004 Mar;172(5):3328-36

Bone Marrow Transplant Program, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.172.5.3328DOI Listing
March 2004

Host conditioning is a primary determinant in modulating the effect of IL-7 on murine graft-versus-host disease.

J Immunol 2004 Mar;172(5):3328-36

Bone Marrow Transplant Program, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.172.5.3328DOI Listing
March 2004

Herpes simplex thymidine kinase gene-transduced donor lymphocyte infusions.

Exp Hematol 2003 Oct;31(10):903-10

Northwestern University School of Medicine, Division of Immunotherapy, Chicago, Illinois 60611, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0301-472x(03)00226-1DOI Listing
October 2003

Herpes simplex thymidine kinase gene-transduced donor lymphocyte infusions.

Exp Hematol 2003 Oct;31(10):903-10

Northwestern University School of Medicine, Division of Immunotherapy, Chicago, Illinois 60611, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0301-472x(03)00226-1DOI Listing
October 2003

Herpes simplex thymidine kinase gene-transduced donor lymphocyte infusions.

Exp Hematol 2003 Oct;31(10):903-10

Northwestern University School of Medicine, Division of Immunotherapy, Chicago, Illinois 60611, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0301-472x(03)00226-1DOI Listing
October 2003

Role of the passive apoptotic pathway in graft-versus-host disease.

J Immunol 2002 Aug;169(3):1626-33

Department of Medicine and Bone Marrow Transplant Program, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.169.3.1626DOI Listing
August 2002